3a16 - Revision history

OCA at 14:06, 1 November 2023

OCA — Wed, 01 Nov 2023 14:06:29 GMT

←Older revision		Revision as of 14:06, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3a16' size='340' side='right'caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3a16' size='340' side='right'caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium~~ erythropolis~~" gray and thornton 1928~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A16 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A16 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>oxd ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1833~~ "~~Mycobacterium erythropolis~~" ~~Gray and Thornton 1928])~~<~~/td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [https://pdbe.org/3a16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [https://www.ebi.ac.uk/pdbsum/3a16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a16 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [https://pdbe.org/3a16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [https://www.ebi.ac.uk/pdbsum/3a16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a16 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/OXD_RHOER OXD_RHOER] Catalyzes the dehydration of aldoximes to their corresponding nitrile (PubMed:16233624, PubMed:19740758). Is active toward various arylalkyl- and alkyl-aldoximes, and to a lesser extent toward aryl-aldoximes (PubMed:16233624).<ref>PMID:16233624</ref> <ref>PMID:19740758</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
-	[[Category: Aliphatic aldoxime dehydratase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aono, S]]	+	[[Category: Rhodococcus erythropolis]]
-	[[Category: Asano, Y]]	+	[[Category: Aono S]]
-	[[Category: Kato, Y]]	+	[[Category: Asano Y]]
-	[[Category: Sawai, H]]	+	[[Category: Kato Y]]
-	[[Category: Shiro, Y]]	+	[[Category: Sawai H]]
-	[[Category: Sugimoto, H]]	+	[[Category: Shiro Y]]
-	~~[[Category: Beta barrel]]~~	+	[[Category: Sugimoto H]]
-	~~[[Category: Heme protein]]~~	+
-	~~[[Category: Lyase~~]]	+

OCA at 16:14, 22 December 2021

OCA — Wed, 22 Dec 2021 16:14:13 GMT

←Older revision		Revision as of 16:14, 22 December 2021
Line 1:		Line 1:

	==Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime==		==Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime==
-	<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='3a16' size='340' side='right'caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3A16 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A16 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [~~http~~://pdbe.org/3a16 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3a16 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3a16 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [https://pdbe.org/3a16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [https://www.ebi.ac.uk/pdbsum/3a16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a16 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 35:		Line 35:
	[[Category: Mycobacterium erythropolis gray and thornton 1928]]		[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
		+	[[Category: Large Structures]]
	[[Category: Aono, S]]		[[Category: Aono, S]]
	[[Category: Asano, Y]]		[[Category: Asano, Y]]

OCA at 07:26, 18 October 2018

OCA — Thu, 18 Oct 2018 07:26:58 GMT

←Older revision		Revision as of 07:26, 18 October 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime==		==Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime==
	<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://pdbe.org/3a16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://pdbe.org/3a16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a16 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a16_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a16_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:20, 8 February 2016

OCA — Mon, 08 Feb 2016 17:20:24 GMT

←Older revision		Revision as of 17:20, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodococcus_erythropolis Rhodococcus~~ erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A16 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A16 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 ~~Rhodococcus~~ erythropolis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://pdbe.org/3a16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a16 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3a16" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
-	[[Category: Rhodococcus erythropolis]]
	[[Category: Aono, S]]		[[Category: Aono, S]]
	[[Category: Asano, Y]]		[[Category: Asano, Y]]

OCA at 08:31, 20 January 2015

OCA — Tue, 20 Jan 2015 08:31:17 GMT

←Older revision		Revision as of 08:31, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A16 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A16 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 Rhodococcus erythropolis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 Rhodococcus erythropolis])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
-	[[Category: Aono, S.]]	+	[[Category: Aono, S]]
-	[[Category: Asano, Y.]]	+	[[Category: Asano, Y]]
-	[[Category: Kato, Y.]]	+	[[Category: Kato, Y]]
-	[[Category: Sawai, H.]]	+	[[Category: Sawai, H]]
-	[[Category: Shiro, Y.]]	+	[[Category: Shiro, Y]]
-	[[Category: Sugimoto, H.]]	+	[[Category: Sugimoto, H]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Heme protein]]		[[Category: Heme protein]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 05:08, 2 October 2014

OCA — Thu, 02 Oct 2014 05:08:30 GMT

←Older revision		Revision as of 05:08, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~3a16.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime==
		+	<StructureSection load='3a16' size='340' side='right' caption='[[3a16]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A16 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PXO:(1Z)-PROPANAL+OXIME'>PXO</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a15\|3a15]], [[3a17\|3a17]], [[3a18\|3a18]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oxd ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 Rhodococcus erythropolis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aliphatic_aldoxime_dehydratase Aliphatic aldoxime dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.5 4.99.1.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a16 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a16 RCSB], [http://www.ebi.ac.uk/pdbsum/3a16 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/3a16_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aldoxime dehydratase (Oxd) catalyzes the dehydration of aldoximes (R-CH=N-OH) to their corresponding nitrile (R-C triple bond N). Oxd is a heme-containing enzyme that catalyzes the dehydration reaction as its physiological function. We have determined the first two structures of Oxd: the substrate-free OxdRE at 1.8 A resolution and the n-butyraldoxime- and propionaldoxime-bound OxdREs at 1.8 and 1.6 A resolutions, respectively. Unlike other heme enzymes, the organic substrate is directly bound to the heme iron in OxdRE. We determined the structure of the Michaelis complex of OxdRE by using the unique substrate binding and activity regulation properties of Oxd. The Michaelis complex was prepared by x-ray cryoradiolytic reduction of the ferric dead-end complex in which Oxd contains a Fe(3+) heme form. The crystal structures reveal the mechanism of substrate recognition and the catalysis of OxdRE.

-	~~{{STRUCTURE_3a16\| PDB=3a16 \| SCENE= }}~~	+	X-ray crystal structure of michaelis complex of aldoxime dehydratase.,Sawai H, Sugimoto H, Kato Y, Asano Y, Shiro Y, Aono S J Biol Chem. 2009 Nov 13;284(46):32089-96. Epub 2009 Sep 8. PMID:19740758<ref>PMID:19740758</ref>

-	~~===Crystal Structure~~ of ~~Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19740758}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3a16]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019740758<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]

OCA: Protected "3a16" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:02:30 GMT

Protected "3a16" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:02, 7 January 2013

OCA at 21:02, 7 January 2013

OCA — Mon, 07 Jan 2013 21:02:27 GMT

←Older revision		Revision as of 21:02, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3a16.png\|left\|200px]]		[[Image:3a16.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3a16", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3a16\| PDB=3a16 \| SCENE= }}		{{STRUCTURE_3a16\| PDB=3a16 \| SCENE= }}

	===Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===		===Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19740758}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19740758 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19740758}}		{{ABSTRACT_PUBMED_19740758}}

	==About this Structure==		==About this Structure==
-	~~3A16~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].	+	[[3a16]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19740758~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019740758</ref><references group="xtra"/>
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
Line 35:		Line 23:
	[[Category: Heme protein]]		[[Category: Heme protein]]
	[[Category: Lyase]]		[[Category: Lyase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 16:37:04 2009''

OCA at 14:37, 18 November 2009

OCA — Wed, 18 Nov 2009 14:37:05 GMT

←Older revision		Revision as of 14:37, 18 November 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3a16.~~jpg~~\|left\|200px]]	+	[[Image:3a16.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===		===Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19740758}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19740758 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19740758}}

	==About this Structure==		==About this Structure==
	3A16 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].		3A16 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19740758</ref><references group="xtra"/>
	[[Category: Aliphatic aldoxime dehydratase]]		[[Category: Aliphatic aldoxime dehydratase]]
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
Line 27:		Line 36:
	[[Category: Lyase]]		[[Category: Lyase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 9 09~~:42:45 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 16:37:04 2009''

OCA at 06:42, 9 September 2009

OCA — Wed, 09 Sep 2009 06:42:47 GMT

←Older revision		Revision as of 06:42, 9 September 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3a16.jpg\|left\|200px]]

-	The ~~entry 3a16~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3a16", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3a16\| PDB=3a16 \| SCENE= }}

-	~~Authors: Sawai, H., Sugimoto, H., Kato, Y., Asano, Y., Shiro, Y., Aono, S.~~	+	===Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime===

-	Description: Crystal Structure of Aldoxime Dehydratase (OxdRE) in Complex with Propionaldoxime

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Apr 15~~ 09:45:27 2009''	+	==About this Structure==
		+	3A16 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A16 OCA].
		+	[[Category: Aliphatic aldoxime dehydratase]]
		+	[[Category: Rhodococcus erythropolis]]
		+	[[Category: Aono, S.]]
		+	[[Category: Asano, Y.]]
		+	[[Category: Kato, Y.]]
		+	[[Category: Sawai, H.]]
		+	[[Category: Shiro, Y.]]
		+	[[Category: Sugimoto, H.]]
		+	[[Category: Beta barrel]]
		+	[[Category: Heme protein]]
		+	[[Category: Lyase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 9 09:42:45 2009''