3a3f - Revision history

OCA at 16:16, 22 December 2021

OCA — Wed, 22 Dec 2021 16:16:12 GMT

←Older revision		Revision as of 16:16, 22 December 2021
Line 1:		Line 1:

	==Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)==		==Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)==
-	<StructureSection load='3a3f' size='340' side='right' caption='[[3a3f]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3a3f' size='340' side='right'caption='[[3a3f]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3a3f]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3A3F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3a3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A3F FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMZ:(2R,4S)-5,5-DIMETHYL-2-[(1R)-2-OXO-1-({(2R)-2-[(2-OXOIMIDAZOLIDIN-1-YL)AMINO]-2-PHENYLACETYL}AMINO)ETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>FMZ</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMZ:(2R,4S)-5,5-DIMETHYL-2-[(1R)-2-OXO-1-({(2R)-2-[(2-OXOIMIDAZOLIDIN-1-YL)AMINO]-2-PHENYLACETYL}AMINO)ETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>FMZ</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a3d\|3a3d]], [[3a3e\|3a3e]], [[3a3i\|3a3i]], [[3a3j\|3a3j]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3a3d\|3a3d]], [[3a3e\|3a3e]], [[3a3i\|3a3i]], [[3a3j\|3a3j]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dacB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dacB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3a3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a3f OCA], [~~http~~://pdbe.org/3a3f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3a3f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3a3f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3a3f ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a3f OCA], [https://pdbe.org/3a3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a3f RCSB], [https://www.ebi.ac.uk/pdbsum/3a3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a3f ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Penicillin-binding protein\|Penicillin-binding protein]]	+	*[[Penicillin-binding protein 3D structures\|Penicillin-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium influenzae lehmann and neumann 1896]]		[[Category: Bacterium influenzae lehmann and neumann 1896]]
		+	[[Category: Large Structures]]
	[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]		[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
	[[Category: Kawai, F]]		[[Category: Kawai, F]]

OCA at 06:56, 18 October 2018

OCA — Thu, 18 Oct 2018 06:56:40 GMT

←Older revision		Revision as of 06:56, 18 October 2018
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/3a3f_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/3a3f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:20, 11 August 2016

OCA — Thu, 11 Aug 2016 07:20:40 GMT

←Older revision		Revision as of 07:20, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)==		==Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)==
	<StructureSection load='3a3f' size='340' side='right' caption='[[3a3f]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3a3f' size='340' side='right' caption='[[3a3f]], [[Resolution\|resolution]] 2.10Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dacB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dacB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a3f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a3f RCSB], [http://www.ebi.ac.uk/pdbsum/3a3f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a3f OCA], [http://pdbe.org/3a3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a3f RCSB], [http://www.ebi.ac.uk/pdbsum/3a3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a3f ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a3f ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3a3f" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 07:49, 20 January 2015

OCA — Tue, 20 Jan 2015 07:49:39 GMT

←Older revision		Revision as of 07:49, 20 January 2015
Line 36:		Line 36:
	[[Category: Bacterium influenzae lehmann and neumann 1896]]		[[Category: Bacterium influenzae lehmann and neumann 1896]]
	[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]		[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
-	[[Category: Kawai, F.]]	+	[[Category: Kawai, F]]
-	[[Category: Park, S Y.]]	+	[[Category: Park, S Y]]
-	[[Category: Roper, D I.]]	+	[[Category: Roper, D I]]
-	[[Category: Tame, J R.H.]]	+	[[Category: Tame, J R.H]]
	[[Category: Dacb]]		[[Category: Dacb]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Pbp4]]		[[Category: Pbp4]]
	[[Category: Penicillin binding protein 4]]		[[Category: Penicillin binding protein 4]]

OCA at 05:53, 10 October 2014

OCA — Fri, 10 Oct 2014 05:53:11 GMT

←Older revision		Revision as of 05:53, 10 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3a3f\| PDB=3a3f \| SCENE= }}~~	+	==Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)==
-	===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===	+	<StructureSection load='3a3f' size='340' side='right' caption='[[3a3f]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	{~~{ABSTRACT_PUBMED_19958776}~~}	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3a3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A3F FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMZ:(2R,4S)-5,5-DIMETHYL-2-[(1R)-2-OXO-1-({(2R)-2-[(2-OXOIMIDAZOLIDIN-1-YL)AMINO]-2-PHENYLACETYL}AMINO)ETHYL]-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>FMZ</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3a3d\|3a3d]], [[3a3e\|3a3e]], [[3a3i\|3a3i]], [[3a3j\|3a3j]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dacB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 "Bacterium influenzae" Lehmann and Neumann 1896])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a3f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a3f RCSB], [http://www.ebi.ac.uk/pdbsum/3a3f PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/3a3f_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined high-resolution apo crystal structures of two low molecular weight penicillin-binding proteins (PBPs), PBP4 and PBP5, from Haemophilus influenzae, one of the most frequently found pathogens in the upper respiratory tract of children. Novel beta-lactams with notable antimicrobial activity have been designed, and crystal structures of PBP4 complexed with ampicillin and two of the novel molecules have also been determined. Comparing the apo form with those of the complexes, we find that the drugs disturb the PBP4 structure and weaken X-ray diffraction, to very different extents. PBP4 has recently been shown to act as a sensor of the presence of penicillins in Pseudomonas aeruginosa, and our models offer a clue to the structural basis for this effect. Covalently attached penicillins press against a phenylalanine residue near the active site and disturb the deacylation step. The ready inhibition of PBP4 by beta-lactams compared to PBP5 also appears to be related to the weaker interactions holding key residues in a catalytically competent position.

-	~~==About this Structure==~~	+	Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae.,Kawai F, Clarke TB, Roper DI, Han GJ, Hwang KY, Unzai S, Obayashi E, Park SY, Tame JR J Mol Biol. 2010 Feb 26;396(3):634-45. Epub 2009 Dec 1. PMID:19958776<ref>PMID:19958776</ref>
-	~~[[3a3f]] is a 2 chain structure with sequence~~ from ~~[http~~:~~//en~~.~~wikipedia~~.~~org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3A3F OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Penicillin-binding protein\|Penicillin-binding protein]]		*[[Penicillin-binding protein\|Penicillin-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:019958776</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacterium influenzae lehmann and neumann 1896]]		[[Category: Bacterium influenzae lehmann and neumann 1896]]
	[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]		[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]

OCA at 11:52, 20 November 2013

OCA — Wed, 20 Nov 2013 11:52:44 GMT

←Older revision		Revision as of 11:52, 20 November 2013
Line 1:		Line 1:
-	[[Image:3a3f.png\|left\|200px]]
-
	{{STRUCTURE_3a3f\| PDB=3a3f \| SCENE= }}		{{STRUCTURE_3a3f\| PDB=3a3f \| SCENE= }}
-
	===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===		===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===
-
	{{ABSTRACT_PUBMED_19958776}}		{{ABSTRACT_PUBMED_19958776}}

	==About this Structure==		==About this Structure==
-	[[3a3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Haemophilus_influenzae Haemophilus~~ influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].	+	[[3a3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].

	==See Also==		==See Also==
Line 14:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019958776</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019958776</ref><references group="xtra"/><references/>
-	[[Category: ~~Haemophilus~~ influenzae]]	+	[[Category: Bacterium influenzae lehmann and neumann 1896]]
	[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]		[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
	[[Category: Kawai, F.]]		[[Category: Kawai, F.]]

OCA at 18:12, 20 October 2012

OCA — Sat, 20 Oct 2012 18:12:08 GMT

←Older revision		Revision as of 18:12, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3a3f]] is a 2 chain structure ~~of [[Penicillin-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].	+	[[3a3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].

	==See Also==		==See Also==

OCA: Protected "3a3f" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 03:20:19 GMT

Protected "3a3f" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:20, 27 July 2012

OCA at 03:20, 27 July 2012

OCA — Fri, 27 Jul 2012 03:20:17 GMT

←Older revision		Revision as of 03:20, 27 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3a3f.png\|left\|200px]]
-	[[Image:3a3f.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3a3f", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3a3f\| PDB=3a3f \| SCENE= }}		{{STRUCTURE_3a3f\| PDB=3a3f \| SCENE= }}

	===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===		===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19958776}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19958776 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19958776}}		{{ABSTRACT_PUBMED_19958776}}

	==About this Structure==		==About this Structure==
-	~~3A3F~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].	+	[[3a3f]] is a 2 chain structure of [[Penicillin-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A3F OCA].
		+
		+	==See Also==
		+	*[[Penicillin-binding protein\|Penicillin-binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19958776~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019958776</ref><references group="xtra"/>
	[[Category: Haemophilus influenzae]]		[[Category: Haemophilus influenzae]]
	[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]		[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
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	[[Category: Pbp4]]		[[Category: Pbp4]]
	[[Category: Penicillin binding protein 4]]		[[Category: Penicillin binding protein 4]]
-
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OCA at 05:37, 24 December 2009

OCA — Thu, 24 Dec 2009 05:37:57 GMT

←Older revision		Revision as of 05:37, 24 December 2009
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	===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===		===Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae,complexed with novel beta-lactam (FMZ)===

		+
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		+	The line below this paragraph, {{ABSTRACT_PUBMED_19958776}}, adds the Publication Abstract to the page
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		+	-->
		+	{{ABSTRACT_PUBMED_19958776}}

	==About this Structure==		==About this Structure==
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	[[Category: Penicillin binding protein 4]]		[[Category: Penicillin binding protein 4]]

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