3ahm - Revision history

OCA at 09:26, 21 February 2024

OCA — Wed, 21 Feb 2024 09:26:45 GMT

←Older revision		Revision as of 09:26, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3ahm' size='340' side='right'caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ahm' size='340' side='right'caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ahm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Geobacillus_sp.~~_mo~~-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3AHM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ahm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_sp._MO-1 Geobacillus sp. MO-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AHM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[3ahn\|3ahn]]~~, ~~[[3aho\|3aho]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [~~http~~://pdbe.org/3ahm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ahm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [https://pdbe.org/3ahm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [https://www.ebi.ac.uk/pdbsum/3ahm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q4W803_9BACI Q4W803_9BACI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ahm ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ahm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Pz-peptidase A, from the thermophilic bacterium Geobacillus collagenovorans MO-1, hydrolyzes a synthetic peptide substrate, 4-phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg (Pz-PLGPR), which contains a collagen-specific tripeptide sequence, -Gly-Pro-X-, but does not act on collagen proteins themselves. The mammalian enzyme, thimet oligopeptidase (TOP), which has comparable functions with bacterial Pz-peptidases but limited identity at the primary sequence level, has recently been subjected to x-ray crystallographic analysis; however, no crystal structure has yet been reported for complexes of TOP with substrate analogues. Here, we report crystallization of recombinant Pz-peptidase A in complex with two phosphinic peptide inhibitors (PPIs) that also function as inhibitors of TOP and determination of the crystal structure of these complexes at 1.80-2.00 A resolution. The most striking difference between Pz-peptidase A and TOP is that there is no channel running the length of bacterial protein. Whereas the structure of TOP resembles an open bivalve, that of Pz-peptidase A is closed and globular. This suggests that collagenous peptide substrates enter the tunnel at the top gateway of the closed Pz-peptidase A molecule, and reactant peptides are released from the bottom gateway after cleavage at the active site located in the center of the tunnel. One of the two PPIs, PPI-2, which contains the collagen-specific sequence, helped to clarify the exquisite structure and reaction mechanism of Pz-peptidase A toward collagenous peptides. This study describes the mode of substrate binding and its implication for the mammalian enzymes.
-
-	The exquisite structure and reaction mechanism of bacterial Pz-peptidase A toward collagenous peptides: X-ray crystallographic structure analysis of PZ-peptidase a reveals differences from mammalian thimet oligopeptidase.,Kawasaki A, Nakano H, Hosokawa A, Nakatsu T, Kato H, Watanabe K J Biol Chem. 2010 Nov 5;285(45):34972-80. Epub 2010 Sep 3. PMID:20817732<ref>PMID:20817732</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3ahm" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Geobacillus sp. mo-1]]	+	[[Category: Geobacillus sp. MO-1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Nakano, H]]	+	[[Category: Nakano H]]
-	~~[[Category: Hydrolase~~]]	+

OCA at 12:22, 29 July 2020

OCA — Wed, 29 Jul 2020 12:22:27 GMT

←Older revision		Revision as of 12:22, 29 July 2020
Line 1:		Line 1:

	==Pz peptidase a==		==Pz peptidase a==
-	<StructureSection load='3ahm' size='340' side='right' caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3ahm' size='340' side='right'caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ahm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_sp._mo-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3AHM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ahm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_sp._mo-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3AHM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://pdbe.org/3ahm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://pdbe.org/3ahm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Geobacillus sp. mo-1]]		[[Category: Geobacillus sp. mo-1]]
		+	[[Category: Large Structures]]
	[[Category: Nakano, H]]		[[Category: Nakano, H]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 08:03, 24 October 2018

OCA — Wed, 24 Oct 2018 08:03:54 GMT

←Older revision		Revision as of 08:03, 24 October 2018
Line 1:		Line 1:
		+
	==Pz peptidase a==		==Pz peptidase a==
	<StructureSection load='3ahm' size='340' side='right' caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ahm' size='340' side='right' caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://pdbe.org/3ahm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://pdbe.org/3ahm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ahm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ah/3ahm_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ah/3ahm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ahm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:48, 16 December 2015

OCA — Wed, 16 Dec 2015 07:48:41 GMT

←Older revision		Revision as of 07:48, 16 December 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://pdbe.org/3ahm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pz-peptidase A, from the thermophilic bacterium Geobacillus collagenovorans MO-1, hydrolyzes a synthetic peptide substrate, 4-phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg (Pz-PLGPR), which contains a collagen-specific tripeptide sequence, -Gly-Pro-X-, but does not act on collagen proteins themselves. The mammalian enzyme, thimet oligopeptidase (TOP), which has comparable functions with bacterial Pz-peptidases but limited identity at the primary sequence level, has recently been subjected to x-ray crystallographic analysis; however, no crystal structure has yet been reported for complexes of TOP with substrate analogues. Here, we report crystallization of recombinant Pz-peptidase A in complex with two phosphinic peptide inhibitors (PPIs) that also function as inhibitors of TOP and determination of the crystal structure of these complexes at 1.80-2.00 A resolution. The most striking difference between Pz-peptidase A and TOP is that there is no channel running the length of bacterial protein. Whereas the structure of TOP resembles an open bivalve, that of Pz-peptidase A is closed and globular. This suggests that collagenous peptide substrates enter the tunnel at the top gateway of the closed Pz-peptidase A molecule, and reactant peptides are released from the bottom gateway after cleavage at the active site located in the center of the tunnel. One of the two PPIs, PPI-2, which contains the collagen-specific sequence, helped to clarify the exquisite structure and reaction mechanism of Pz-peptidase A toward collagenous peptides. This study describes the mode of substrate binding and its implication for the mammalian enzymes.
		+
		+	The exquisite structure and reaction mechanism of bacterial Pz-peptidase A toward collagenous peptides: X-ray crystallographic structure analysis of PZ-peptidase a reveals differences from mammalian thimet oligopeptidase.,Kawasaki A, Nakano H, Hosokawa A, Nakatsu T, Kato H, Watanabe K J Biol Chem. 2010 Nov 5;285(45):34972-80. Epub 2010 Sep 3. PMID:20817732<ref>PMID:20817732</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3ahm" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:58, 25 January 2015

OCA — Sun, 25 Jan 2015 09:58:20 GMT

←Older revision		Revision as of 09:58, 25 January 2015
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Geobacillus sp. mo-1]]		[[Category: Geobacillus sp. mo-1]]
-	[[Category: Nakano, H.]]	+	[[Category: Nakano, H]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 09:25, 5 November 2014

OCA — Wed, 05 Nov 2014 09:25:55 GMT

←Older revision		Revision as of 09:25, 5 November 2014
Line 1:		Line 1:
-	~~[[Image:3ahm.png\|left\|200px]]~~	+	==Pz peptidase a==
-		+	<StructureSection load='3ahm' size='340' side='right' caption='[[3ahm]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~{{STRUCTURE_3ahm\| PDB=3ahm \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3ahm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_sp._mo-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AHM FirstGlance]. <br>
-	===Pz peptidase a===	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ahn\|3ahn]], [[3aho\|3aho]]</td></tr>
-	~~{{ABSTRACT_PUBMED_020817732}}~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ahm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ahm RCSB], [http://www.ebi.ac.uk/pdbsum/3ahm PDBsum]</span></td></tr>
-		+	</table>
-	==~~About this Structure~~==	+	== Evolutionary Conservation ==
-	[[3ahm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_sp._mo-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA].	+	[[Image:Consurf_key_small.gif\|200px\|right]]
-		+	Check<jmol>
-	==~~Reference~~==	+	<jmolCheckbox>
-	<~~ref group~~="~~xtra~~">~~PMID~~:~~020817732~~</~~ref~~><~~references group~~="~~xtra~~"/>	+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ah/3ahm_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Geobacillus sp. mo-1]]		[[Category: Geobacillus sp. mo-1]]
	[[Category: Nakano, H.]]		[[Category: Nakano, H.]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA: Protected "3ahm" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:40:10 GMT

Protected "3ahm" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:40, 7 January 2013

OCA at 21:40, 7 January 2013

OCA — Mon, 07 Jan 2013 21:40:05 GMT

←Older revision		Revision as of 21:40, 7 January 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3ahm.png\|left\|200px]]
-	[[Image:3ahm.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ahm", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ahm\| PDB=3ahm \| SCENE= }}		{{STRUCTURE_3ahm\| PDB=3ahm \| SCENE= }}

	===Pz peptidase a===		===Pz peptidase a===

		+	{{ABSTRACT_PUBMED_020817732}}

	==About this Structure==		==About this Structure==
-	~~3AHM~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/~~Bacteria Bacteria~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA].	+	[[3ahm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_sp._mo-1 Geobacillus sp. mo-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA].
-	[[Category: ~~Bacteria~~]]	+
		+	==Reference==
		+	<ref group="xtra">PMID:020817732</ref><references group="xtra"/>
		+	[[Category: Geobacillus sp. mo-1]]
	[[Category: Nakano, H.]]		[[Category: Nakano, H.]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:53:36 2010''

OCA at 04:45, 25 August 2010

OCA — Wed, 25 Aug 2010 04:45:46 GMT

←Older revision		Revision as of 04:45, 25 August 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ahm.jpg\|left\|200px]]

-	The ~~entry 3ahm~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ahm", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ahm\| PDB=3ahm \| SCENE= }}

-	~~Authors: Hiroaki Nakano~~	+	===Pz peptidase a===

-	Description: PZ PEPTIDASE A

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 5 11~~:33:58 2010''	+	==About this Structure==
		+	3AHM is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AHM OCA].
		+	[[Category: Bacteria]]
		+	[[Category: Nakano, H.]]
		+	[[Category: Hydrolase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:53:36 2010''

OCA: New page: '''Unreleased structure''' The entry 3ahm is ON HOLD Authors: Hiroaki Nakano Description: PZ PEPTIDASE A ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:33:58 2...

OCA — Wed, 05 May 2010 08:33:59 GMT

New page: '''Unreleased structure''' The entry 3ahm is ON HOLD Authors: Hiroaki Nakano Description: PZ PEPTIDASE A ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:33:58 2...

New page

'''Unreleased structure'''

The entry 3ahm is ON HOLD

Authors: Hiroaki Nakano

Description: PZ PEPTIDASE A

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:33:58 2010''