3aiv - Revision history

OCA at 15:47, 4 October 2023

OCA — Wed, 04 Oct 2023 15:47:08 GMT

←Older revision		Revision as of 15:47, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='3aiv' size='340' side='right'caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3aiv' size='340' side='right'caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Rye Rye~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AIV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HBO:2,4~~-~~DIHYDROXY-7-(METHYLOXY)-2H-1~~,~~4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>ScGlu ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id~~=4550 Rye])</td></tr>~~	+
-	~~<tr id='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Beta~~-~~glucosidase Beta~~-~~glucosidase]~~, ~~with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=~~3~~.2.1.21 3.2.1.21]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [https://pdbe.org/3aiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [https://www.ebi.ac.uk/pdbsum/3aiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiv ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [https://pdbe.org/3aiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [https://www.ebi.ac.uk/pdbsum/3aiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HGGL_SECCE HGGL_SECCE]] Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides. The preferred substrate is DIBOA-beta-D-glucoside. Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.<ref>PMID:10773341</ref> [PDB:3AIU]	+	[https://www.uniprot.org/uniprot/HGGL_SECCE HGGL_SECCE] Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides. The preferred substrate is DIBOA-beta-D-glucoside. Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.<ref>PMID:10773341</ref> [PDB:3AIU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Beta-glucosidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Rye~~]]	+	[[Category: Secale cereale]]
-	[[Category: Miyamoto, T]]	+	[[Category: Miyamoto T]]
-	[[Category: Nakamura, C]]	+	[[Category: Nakamura C]]
-	[[Category: Sue, M]]	+	[[Category: Sue M]]
-	[[Category: Yajima, S]]	+	[[Category: Yajima S]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Tim barrel~~]]	+

OCA at 14:54, 29 December 2021

OCA — Wed, 29 Dec 2021 14:54:27 GMT

←Older revision		Revision as of 14:54, 29 December 2021
Line 1:		Line 1:

	==Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA==		==Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA==
-	<StructureSection load='3aiv' size='340' side='right' caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3aiv' size='340' side='right'caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rye Rye]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3AIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rye Rye]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AIV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ScGlu ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4550 Rye])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ScGlu ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4550 Rye])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [~~http~~://pdbe.org/3aiv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3aiv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [https://pdbe.org/3aiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [https://www.ebi.ac.uk/pdbsum/3aiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HGGL_SECCE HGGL_SECCE]] Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides. The preferred substrate is DIBOA-beta-D-glucoside. Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.<ref>PMID:10773341</ref> [PDB:3AIU]	+	[[https://www.uniprot.org/uniprot/HGGL_SECCE HGGL_SECCE]] Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides. The preferred substrate is DIBOA-beta-D-glucoside. Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.<ref>PMID:10773341</ref> [PDB:3AIU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[Beta-glucosidase\|Beta-glucosidase]]	+	*[[Beta-glucosidase 3D structures\|Beta-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
		+	[[Category: Large Structures]]
	[[Category: Rye]]		[[Category: Rye]]
	[[Category: Miyamoto, T]]		[[Category: Miyamoto, T]]

OCA at 11:14, 11 August 2016

OCA — Thu, 11 Aug 2016 11:14:57 GMT

←Older revision		Revision as of 11:14, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA==		==Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA==
	<StructureSection load='3aiv' size='340' side='right' caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3aiv' size='340' side='right' caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Secale_cereale Secale cereale~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AIV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rye Rye]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AIV FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ScGlu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4550 ~~Secale cereale~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ScGlu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4550 Rye])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [http://www.ebi.ac.uk/pdbsum/3aiv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [http://pdbe.org/3aiv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [http://www.ebi.ac.uk/pdbsum/3aiv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3aiv ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HGGL_SECCE HGGL_SECCE]] Involved in defense of young plant parts against pests via the production of benzoxazolinones (hydroxamic acids) from hydroxamic acid glucosides. The preferred substrate is DIBOA-beta-D-glucoside. Can also use esculin and genistein glucoside as substrates, but no activity with salicin, p-nitrophenyl-alpha-glucoside or substrates related to cell wall components.<ref>PMID:10773341</ref> [PDB:3AIU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3aiv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
-	[[Category: ~~Secale cereale~~]]	+	[[Category: Rye]]
	[[Category: Miyamoto, T]]		[[Category: Miyamoto, T]]
	[[Category: Nakamura, C]]		[[Category: Nakamura, C]]

OCA at 09:17, 25 January 2015

OCA — Sun, 25 Jan 2015 09:17:56 GMT

←Older revision		Revision as of 09:17, 25 January 2015
Line 26:		Line 26:
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
	[[Category: Secale cereale]]		[[Category: Secale cereale]]
-	[[Category: Miyamoto, T.]]	+	[[Category: Miyamoto, T]]
-	[[Category: Nakamura, C.]]	+	[[Category: Nakamura, C]]
-	[[Category: Sue, M.]]	+	[[Category: Sue, M]]
-	[[Category: Yajima, S.]]	+	[[Category: Yajima, S]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Tim barrel]]		[[Category: Tim barrel]]

OCA at 09:24, 5 November 2014

OCA — Wed, 05 Nov 2014 09:24:23 GMT

←Older revision		Revision as of 09:24, 5 November 2014
Line 1:		Line 1:
-	[[~~Image:~~3aiv.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA==
		+	<StructureSection load='3aiv' size='340' side='right' caption='[[3aiv]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AIV FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBO:2,4-DIHYDROXY-7-(METHYLOXY)-2H-1,4-BENZOXAZIN-3(4H)-ONE'>HBO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2dga\|2dga]], [[3aiq\|3aiq]], [[3air\|3air]], [[3ais\|3ais]], [[3aiu\|3aiu]], [[3aiw\|3aiw]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ScGlu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4550 Secale cereale])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3aiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aiv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3aiv RCSB], [http://www.ebi.ac.uk/pdbsum/3aiv PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The beta-D-glucosidases from wheat (Triticum aestivum) and rye (Secale cereale) hydrolyze benzoxazinone-glucose conjugates. Although wheat and rye glucosidases have high sequence identity, they have different substrate preferences; the wheat enzyme favors DIMBOA-Glc (2-O-beta-D-glucopyranosyl-4-hydroxy-7-methoxy-1,4-benzoxazin-3-one) over DIBOA-Glc (7-demethoxy-DIMBOA-Glc), whereas the rye enzyme preference is the opposite. To investigate the mechanism of substrate binding, we analyzed crystal structures of an inactive mutant of the wheat glucosidase complexed with the natural substrate DIMBOA-Glc, wheat and rye glucosidases complexed with an aglycone DIMBOA, and wheat and rye glucosidases complexed with an inhibitor 2-fluoro-2-deoxy-beta-D-glucose. The binding position of substrate in the active site was determined but interaction between the substrate and Ser-464 or Leu-465 was not observed, although amino acid residues at these two positions are the only structural distinctions between wheat and rye glucosidase catalytic pockets. Variation at these two positions alters the width of the pocket entrance, which may relate to observed differences in substrate specificity. The side chain of Glu-462 that forms hydrogen bonds with the glucose moiety of DIMBOA-Glc moved deeper into the pocket upon substrate binding, and mutation of this residue dramatically decreased enzyme activity.

-	~~{{STRUCTURE_3aiv\| PDB=3aiv \| SCENE= }}~~	+	Active-site architecture of benzoxazinone-glucoside beta-D-glucosidases in Triticeae.,Sue M, Nakamura C, Miyamoto T, Yajima S Plant Sci. 2011 Feb;180(2):268-75. Epub 2010 Sep 19. PMID:21421370<ref>PMID:21421370</ref>

-	~~===Crystal structure~~ of ~~beta-glucosidase in rye complexed with an aglycone DIMBOA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21421370}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3aiv]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Secale_cereale Secale cereale]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].~~	+

	==See Also==		==See Also==
	*[[Beta-glucosidase\|Beta-glucosidase]]		*[[Beta-glucosidase\|Beta-glucosidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021421370<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
	[[Category: Secale cereale]]		[[Category: Secale cereale]]

OCA at 10:51, 20 October 2012

OCA — Sat, 20 Oct 2012 10:51:28 GMT

←Older revision		Revision as of 10:51, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3aiv]] is a 1 chain structure ~~of [[Beta-glucosidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].	+	[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].

	==See Also==		==See Also==

OCA at 03:29, 26 July 2012

OCA — Thu, 26 Jul 2012 03:29:23 GMT

←Older revision		Revision as of 03:29, 26 July 2012
Line 1:		Line 1:
	[[Image:3aiv.png\|left\|200px]]		[[Image:3aiv.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3aiv", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3aiv\| PDB=3aiv \| SCENE= }}		{{STRUCTURE_3aiv\| PDB=3aiv \| SCENE= }}

	===Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA===		===Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21421370}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21421370 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21421370}}		{{ABSTRACT_PUBMED_21421370}}

OCA at 05:21, 4 April 2012

OCA — Wed, 04 Apr 2012 05:21:59 GMT

←Older revision		Revision as of 05:21, 4 April 2012
Line 1:		Line 1:
-	[[Image:3aiv.~~jpg~~\|left\|200px]]	+	[[Image:3aiv.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA===		===Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21421370}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21421370 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21421370}}

	==About this Structure==		==About this Structure==
-	[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermomicrobium_roseum Thermomicrobium roseum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].	+	[[3aiv]] is a 1 chain structure of [[Beta-glucosidase]] with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].
		+
		+	==See Also==
		+	*[[Beta-glucosidase\|Beta-glucosidase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021421370</ref><references group="xtra"/>
	[[Category: Beta-glucosidase]]		[[Category: Beta-glucosidase]]
-	[[Category: ~~Thermomicrobium roseum~~]]	+	[[Category: Secale cereale]]
	[[Category: Miyamoto, T.]]		[[Category: Miyamoto, T.]]
	[[Category: Nakamura, C.]]		[[Category: Nakamura, C.]]
	[[Category: Sue, M.]]		[[Category: Sue, M.]]
	[[Category: Yajima, S.]]		[[Category: Yajima, S.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Tim barrel]]

OCA: Protected "3aiv" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2011 09:56:02 GMT

Protected "3aiv" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:56, 23 February 2011

OCA at 09:55, 23 February 2011

OCA — Wed, 23 Feb 2011 09:55:59 GMT

←Older revision		Revision as of 09:55, 23 February 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3aiv.jpg\|left\|200px]]

-	The ~~entry 3aiv~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3aiv", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3aiv\| PDB=3aiv \| SCENE= }}

-	~~Authors: Sue, M., Nakamura, C., Miyamoto, T., Yajima, S.~~	+	===Crystal structure of beta-glucosidase in rye complexed with an aglycone DIMBOA===

-	Description: Crystal structure of beta-glucosidase in rye complexed with a substrate aglycone

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Jul 7 08~~:23:~~32 2010''~~	+	==About this Structure==
		+	[[3aiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermomicrobium_roseum Thermomicrobium roseum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AIV OCA].
		+	[[Category: Beta-glucosidase]]
		+	[[Category: Thermomicrobium roseum]]
		+	[[Category: Miyamoto, T.]]
		+	[[Category: Nakamura, C.]]
		+	[[Category: Sue, M.]]
		+	[[Category: Yajima, S.]]