3auj - Revision history

OCA at 15:56, 4 October 2023

OCA — Wed, 04 Oct 2023 15:56:22 GMT

←Older revision		Revision as of 15:56, 4 October 2023
Line 3:		Line 3:
	<StructureSection load='3auj' size='340' side='right'caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3auj' size='340' side='right'caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_oxytocus_perniciosus"_flugge_1886 "bacillus oxytocus perniciosus" flugge 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=B12:COBALAMIN'>B12</scene>~~, ~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>pddA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~571~~ "~~Bacillus oxytocus perniciosus~~" ~~Flugge 1886]), pddB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddC ([https~~:~~//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886])</td~~></tr>	+
-	<~~tr id~~='~~activity~~'><~~td class="sblockLbl"~~><~~b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [https://pdbe.org/3auj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [https://www.ebi.ac.uk/pdbsum/3auj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3auj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [https://pdbe.org/3auj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [https://www.ebi.ac.uk/pdbsum/3auj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3auj ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q59470_KLEOX Q59470_KLEOX]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus oxytocus perniciosus flugge 1886~~]]	+	[[Category: Klebsiella oxytoca]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Propanediol dehydratase]]~~	+	[[Category: Fukuoka M]]
-	[[Category: Fukuoka, M]]	+	[[Category: Kinoshita K]]
-	[[Category: Kinoshita, K]]	+	[[Category: Shibata T]]
-	[[Category: Shibata, T]]	+	[[Category: Tobimatsu T]]
-	[[Category: Tobimatsu, T]]	+	[[Category: Toraya T]]
-	[[Category: Toraya, T]]	+	[[Category: Yamanishi M]]
-	[[Category: Yamanishi, M]]	+
-	~~[[Category: Alpha/beta barrel]]~~	+
-	~~[[Category: Lyase~~]]	+

OCA at 15:04, 29 December 2021

OCA — Wed, 29 Dec 2021 15:04:52 GMT

←Older revision		Revision as of 15:04, 29 December 2021
Line 1:		Line 1:

	==Structure of diol dehydratase complexed with glycerol==		==Structure of diol dehydratase complexed with glycerol==
-	<StructureSection load='3auj' size='340' side='right' caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3auj' size='340' side='right'caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_oxytocus_perniciosus"_flugge_1886 "bacillus oxytocus perniciosus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_oxytocus_perniciosus"_flugge_1886 "bacillus oxytocus perniciosus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pddA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddC ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pddA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [~~http~~://pdbe.org/3auj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3auj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3auj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [https://pdbe.org/3auj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [https://www.ebi.ac.uk/pdbsum/3auj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3auj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus oxytocus perniciosus flugge 1886]]		[[Category: Bacillus oxytocus perniciosus flugge 1886]]
		+	[[Category: Large Structures]]
	[[Category: Propanediol dehydratase]]		[[Category: Propanediol dehydratase]]
	[[Category: Fukuoka, M]]		[[Category: Fukuoka, M]]

OCA at 09:47, 4 August 2016

OCA — Thu, 04 Aug 2016 09:47:56 GMT

←Older revision		Revision as of 09:47, 4 August 2016
Line 1:		Line 1:
		+
	==Structure of diol dehydratase complexed with glycerol==		==Structure of diol dehydratase complexed with glycerol==
	<StructureSection load='3auj' size='340' side='right' caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3auj' size='340' side='right' caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Klebsiella_oxytoca Klebsiella oxytoca~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_oxytocus_perniciosus"_flugge_1886 "bacillus oxytocus perniciosus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pddA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 ~~Klebsiella oxytoca~~]), pddB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 ~~Klebsiella oxytoca~~]), pddC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 ~~Klebsiella oxytoca~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pddA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886]), pddC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 "Bacillus oxytocus perniciosus" Flugge 1886])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [http://www.ebi.ac.uk/pdbsum/3auj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [http://pdbe.org/3auj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [http://www.ebi.ac.uk/pdbsum/3auj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3auj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3auj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Klebsiella oxytoca~~]]	+	[[Category: Bacillus oxytocus perniciosus flugge 1886]]
	[[Category: Propanediol dehydratase]]		[[Category: Propanediol dehydratase]]
	[[Category: Fukuoka, M]]		[[Category: Fukuoka, M]]

OCA at 13:16, 18 December 2014

OCA — Thu, 18 Dec 2014 13:16:31 GMT

←Older revision		Revision as of 13:16, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3auj~~\| ~~PDB~~=3auj \| ~~SCENE~~= }}	+	==Structure of diol dehydratase complexed with glycerol==
-	===~~Structure of diol~~ dehydratase ~~complexed~~ with ~~glycerol~~===	+	<StructureSection load='3auj' size='340' side='right' caption='[[3auj]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22221669}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3auj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AUJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dio\|1dio]], [[1egm\|1egm]], [[1egv\|1egv]], [[1eex\|1eex]], [[1iwb\|1iwb]], [[1uc4\|1uc4]], [[1uc5\|1uc5]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pddA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 Klebsiella oxytoca]), pddB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 Klebsiella oxytoca]), pddC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=571 Klebsiella oxytoca])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Propanediol_dehydratase Propanediol dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.28 4.2.1.28] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3auj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3auj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3auj RCSB], [http://www.ebi.ac.uk/pdbsum/3auj PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Coenzyme B(12) dependent diol dehydratase undergoes mechanism-based inactivation by glycerol, accompanying the irreversible cleavage of the coenzyme Co-C bond. Bachovchin et al. [Biochemistry16, 1082-1092 (1977)] reported that glycerol bound in the G(S) conformation, in which the pro-S-CH(2) OH group is oriented to the hydrogen-abstracting site, primarily contributes to the inactivation reaction. To understand the mechanism of inactivation by glycerol, we analyzed the X-ray structure of diol dehydratase complexed with cyanocobalamin and glycerol. Glycerol is bound to the active site preferentially in the same conformation as that of (S)-1,2-propanediol, i.e. in the G(S) conformation, with its 3-OH group hydrogen bonded to Seralpha301, but not to nearby Glnalpha336. k(inact) of the Salpha301A, Qalpha336A and Salpha301A/Qalpha336A mutants with glycerol was much smaller than that of the wild-type enzyme. k(cat) /k(inact) showed that the Salpha301A and Qalpha336A mutants are substantially more resistant to glycerol inactivation than the wild-type enzyme, suggesting that Seralpha301 and Glnalpha336 are directly or indirectly involved in the inactivation. The degree of preference for (S)-1,2-propanediol decreased on these mutations. The substrate activities towards longer chain 1,2-diols significantly increased on the Salpha301A/Qalpha336A double mutation, probably because these amino acid substitutions yield more space for accommodating a longer alkyl group on C3 of 1,2-diols. Database Structural data are available in the Protein Data Bank under the accession number 3AUJ. Structured digital abstract * Diol dehydrase gamma subunit, Diol dehydrase beta subunit and Diol dehydrase alpha subunit physically interact by X-ray crystallography (View interaction).

-	~~==About this Structure==~~	+	Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols.,Yamanishi M, Kinoshita K, Fukuoka M, Saito T, Tanokuchi A, Ikeda Y, Obayashi H, Mori K, Shibata N, Tobimatsu T, Toraya T FEBS J. 2012 Mar;279(5):793-804. doi: 10.1111/j.1742-4658.2012.08470.x. Epub 2012, Jan 30. PMID:22221669<ref>PMID:22221669</ref>
-	~~[[3auj]] is a 6~~ chain ~~structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=3AUJ OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:022221669</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Klebsiella oxytoca]]		[[Category: Klebsiella oxytoca]]
	[[Category: Propanediol dehydratase]]		[[Category: Propanediol dehydratase]]
-	[[Category: Fukuoka, M.]]	+	[[Category: Fukuoka, M]]
-	[[Category: Kinoshita, K.]]	+	[[Category: Kinoshita, K]]
-	[[Category: Shibata, T.]]	+	[[Category: Shibata, T]]
-	[[Category: Tobimatsu, T.]]	+	[[Category: Tobimatsu, T]]
-	[[Category: Toraya, T.]]	+	[[Category: Toraya, T]]
-	[[Category: Yamanishi, M.]]	+	[[Category: Yamanishi, M]]
	[[Category: Alpha/beta barrel]]		[[Category: Alpha/beta barrel]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 07:31, 20 June 2013

OCA — Thu, 20 Jun 2013 07:31:33 GMT

←Older revision		Revision as of 07:31, 20 June 2013
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-	[[Image:3auj.png\|left\|200px]]
-
	{{STRUCTURE_3auj\| PDB=3auj \| SCENE= }}		{{STRUCTURE_3auj\| PDB=3auj \| SCENE= }}
-
	===Structure of diol dehydratase complexed with glycerol===		===Structure of diol dehydratase complexed with glycerol===
-
	{{ABSTRACT_PUBMED_22221669}}		{{ABSTRACT_PUBMED_22221669}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:022221669</ref><references group="xtra"/>	+	<ref group="xtra">PMID:022221669</ref><references group="xtra"/><references/>
	[[Category: Klebsiella oxytoca]]		[[Category: Klebsiella oxytoca]]
	[[Category: Propanediol dehydratase]]		[[Category: Propanediol dehydratase]]

OCA at 06:27, 24 October 2012

OCA — Wed, 24 Oct 2012 06:27:14 GMT

←Older revision		Revision as of 06:27, 24 October 2012
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	[[Image:3auj.png\|left\|200px]]		[[Image:3auj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3auj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3auj\| PDB=3auj \| SCENE= }}		{{STRUCTURE_3auj\| PDB=3auj \| SCENE= }}

	===Structure of diol dehydratase complexed with glycerol===		===Structure of diol dehydratase complexed with glycerol===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22221669}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22221669 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_22221669}}		{{ABSTRACT_PUBMED_22221669}}

OCA at 08:45, 29 February 2012

OCA — Wed, 29 Feb 2012 08:45:46 GMT

←Older revision		Revision as of 08:45, 29 February 2012
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-	[[Image:3auj.~~jpg~~\|left\|200px]]	+	[[Image:3auj.png\|left\|200px]]

	<!--		<!--
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	===Structure of diol dehydratase complexed with glycerol===		===Structure of diol dehydratase complexed with glycerol===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22221669}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22221669 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22221669}}

	==About this Structure==		==About this Structure==

OCA at 07:47, 22 February 2012

OCA — Wed, 22 Feb 2012 07:47:31 GMT

←Older revision		Revision as of 07:47, 22 February 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3auj.jpg\|left\|200px]]

-	The ~~entry 3auj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3auj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3auj\| PDB=3auj \| SCENE= }}

-	~~Authors: Yamanishi, M., Kinoshita, K., Fukuoka, M., Shibata, T., Tobimatsu, T., Toraya, T.~~	+	===Structure of diol dehydratase complexed with glycerol===

-	~~Description:~~ Structure ~~of diol dehydratase complexed~~ with ~~glycerol~~	+
		+	==About this Structure==
		+	[[3auj]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AUJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022221669</ref><references group="xtra"/>
		+	[[Category: Klebsiella oxytoca]]
		+	[[Category: Propanediol dehydratase]]
		+	[[Category: Fukuoka, M.]]
		+	[[Category: Kinoshita, K.]]
		+	[[Category: Shibata, T.]]
		+	[[Category: Tobimatsu, T.]]
		+	[[Category: Toraya, T.]]
		+	[[Category: Yamanishi, M.]]
		+	[[Category: Alpha/beta barrel]]
		+	[[Category: Lyase]]

OCA at 05:04, 18 May 2011

OCA — Wed, 18 May 2011 05:04:36 GMT

←Older revision		Revision as of 05:04, 18 May 2011
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3auj is ON HOLD	+	The entry 3auj is ON HOLD until Paper Publication

	Authors: Yamanishi, M., Kinoshita, K., Fukuoka, M., Shibata, T., Tobimatsu, T., Toraya, T.		Authors: Yamanishi, M., Kinoshita, K., Fukuoka, M., Shibata, T., Tobimatsu, T., Toraya, T.

	Description: Structure of diol dehydratase complexed with glycerol		Description: Structure of diol dehydratase complexed with glycerol

OCA at 06:36, 23 March 2011

OCA — Wed, 23 Mar 2011 06:36:48 GMT

←Older revision		Revision as of 06:36, 23 March 2011
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	Authors: Yamanishi, M., Kinoshita, K., Fukuoka, M., Shibata, T., Tobimatsu, T., Toraya, T.		Authors: Yamanishi, M., Kinoshita, K., Fukuoka, M., Shibata, T., Tobimatsu, T., Toraya, T.

-	Description: ~~STRUCTURE OF DIOL DEHYDRATASE COMPLEXED WITH GLYCEROL~~	+	Description: Structure of diol dehydratase complexed with glycerol