3bo0 - Revision history

OCA at 09:30, 21 February 2024

OCA — Wed, 21 Feb 2024 09:30:11 GMT

←Older revision		Revision as of 09:30, 21 February 2024
Line 3:		Line 3:
	<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>		<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from ~~[https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and~~ [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>[[~~3bo1~~\|~~3bo1~~]]~~</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 9.6Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [https://pdbe.org/3bo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [https://pdbe.org/3bo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo0 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The SecY complex associates with the ribosome to form a protein translocation channel in the bacterial plasma membrane. We have used cryo-electron microscopy and quantitative mass spectrometry to show that a nontranslating E. coli ribosome binds to a single SecY complex. The crystal structure of an archaeal SecY complex was then docked into the electron density maps. In the resulting model, two cytoplasmic loops of SecY extend into the exit tunnel near proteins L23, L29, and L24. The loop between transmembrane helices 8 and 9 interacts with helices H59 and H50 in the large subunit RNA, while the 6/7 loop interacts with H7. We also show that point mutations of basic residues within either loop abolish ribosome binding. We suggest that SecY binds to this primary site on the ribosome and subsequently captures and translocates the nascent chain.
-
-	Ribosome binding of a single copy of the SecY complex: implications for protein translocation.,Menetret JF, Schaletzky J, Clemons WM Jr, Osborne AR, Skanland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW Mol Cell. 2007 Dec 28;28(6):1083-92. PMID:18158904<ref>PMID:18158904</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3bo0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[Preprotein translocase\|Preprotein translocase]]	+	*[[Preprotein translocase 3D structures\|Preprotein translocase 3D structures]]
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: Bacillus coli migula 1895]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Akey~~, C W~~]]	+	[[Category: Akey CW]]
-	[[Category: Menetret~~, J F]]~~	+	[[Category: Menetret JF]]
-	~~[[Category: Protein translocation]]~~	+
-	~~[[Category: Ribosome]]~~	+
-	~~[[Category: Ribosome-secy complex~~]]	+

OCA at 08:20, 19 January 2022

OCA — Wed, 19 Jan 2022 08:20:14 GMT

←Older revision		Revision as of 08:20, 19 January 2022
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	<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>		<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [~~http~~://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bo1\|3bo1]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [~~http~~://pdbe.org/3bo0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [https://pdbe.org/3bo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:13, 10 April 2020

OCA — Fri, 10 Apr 2020 17:13:27 GMT

←Older revision		Revision as of 17:13, 10 April 2020
Line 3:		Line 3:
	<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>		<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://pdbe.org/3bo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://pdbe.org/3bo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 17:04, 6 March 2020

OCA — Fri, 06 Mar 2020 17:04:47 GMT

←Older revision		Revision as of 17:04, 6 March 2020
Line 1:		Line 1:

	==Ribosome-SecY complex==		==Ribosome-SecY complex==
-	<~~StructureSection~~ load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>	+	<SX load='3bo0' size='340' side='right' viewer='molstar' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
Line 32:		Line 32:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
	[[Category: Akey, C W]]		[[Category: Akey, C W]]
	[[Category: Menetret, J F]]		[[Category: Menetret, J F]]

OCA at 07:58, 31 October 2018

OCA — Wed, 31 Oct 2018 07:58:49 GMT

←Older revision		Revision as of 07:58, 31 October 2018
Line 1:		Line 1:
		+
	==Ribosome-SecY complex==		==Ribosome-SecY complex==
	<StructureSection load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>		<StructureSection load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://pdbe.org/3bo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://pdbe.org/3bo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:05, 7 February 2016

OCA — Sun, 07 Feb 2016 09:05:06 GMT

←Older revision		Revision as of 09:05, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>		<StructureSection load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://pdbe.org/3bo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3bo0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Akey, C W]]		[[Category: Akey, C W]]

OCA at 11:29, 20 January 2015

OCA — Tue, 20 Jan 2015 11:29:45 GMT

←Older revision		Revision as of 11:29, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Akey, C W.]]	+	[[Category: Akey, C W]]
-	[[Category: Menetret, J F.]]	+	[[Category: Menetret, J F]]
	[[Category: Protein translocation]]		[[Category: Protein translocation]]
	[[Category: Ribosome]]		[[Category: Ribosome]]
	[[Category: Ribosome-secy complex]]		[[Category: Ribosome-secy complex]]

OCA at 21:14, 2 October 2014

OCA — Thu, 02 Oct 2014 21:14:05 GMT

←Older revision		Revision as of 21:14, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~3bo0.~~png~~\|~~left~~\|200px]]	+	==Ribosome-SecY complex==
		+	<StructureSection load='3bo0' size='340' side='right' caption='[[3bo0]], [[Resolution\|resolution]] 9.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BO0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bo1\|3bo1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bo0 RCSB], [http://www.ebi.ac.uk/pdbsum/3bo0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The SecY complex associates with the ribosome to form a protein translocation channel in the bacterial plasma membrane. We have used cryo-electron microscopy and quantitative mass spectrometry to show that a nontranslating E. coli ribosome binds to a single SecY complex. The crystal structure of an archaeal SecY complex was then docked into the electron density maps. In the resulting model, two cytoplasmic loops of SecY extend into the exit tunnel near proteins L23, L29, and L24. The loop between transmembrane helices 8 and 9 interacts with helices H59 and H50 in the large subunit RNA, while the 6/7 loop interacts with H7. We also show that point mutations of basic residues within either loop abolish ribosome binding. We suggest that SecY binds to this primary site on the ribosome and subsequently captures and translocates the nascent chain.

-	~~{{STRUCTURE_3bo0\| PDB=3bo0 \| SCENE= }}~~	+	Ribosome binding of a single copy of the SecY complex: implications for protein translocation.,Menetret JF, Schaletzky J, Clemons WM Jr, Osborne AR, Skanland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW Mol Cell. 2007 Dec 28;28(6):1083-92. PMID:18158904<ref>PMID:18158904</ref>

-	~~===Ribosome-SecY complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_18158904}}~~	+	==See Also==
-		+	*[[Preprotein translocase\|Preprotein translocase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~3bo0~~]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:018158904<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Akey, C W.]]		[[Category: Akey, C W.]]

OCA: Protected "3bo0" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:12:35 GMT

Protected "3bo0" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:12, 7 January 2013

OCA at 20:12, 7 January 2013

OCA — Mon, 07 Jan 2013 20:12:31 GMT

←Older revision		Revision as of 20:12, 7 January 2013
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-	{{Seed}}
	[[Image:3bo0.png\|left\|200px]]		[[Image:3bo0.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3bo0", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3bo0\| PDB=3bo0 \| SCENE= }}		{{STRUCTURE_3bo0\| PDB=3bo0 \| SCENE= }}

	===Ribosome-SecY complex===		===Ribosome-SecY complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18158904}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18158904 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18158904}}		{{ABSTRACT_PUBMED_18158904}}

	==About this Structure==		==About this Structure==
-	~~3BO0~~ is a 7 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA].	+	[[3bo0]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO0 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18158904~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018158904</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Akey, C W.]]		[[Category: Akey, C W.]]
	[[Category: Menetret, J F.]]		[[Category: Menetret, J F.]]
	[[Category: Protein translocation]]		[[Category: Protein translocation]]
		+	[[Category: Ribosome]]
	[[Category: Ribosome-secy complex]]		[[Category: Ribosome-secy complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 08:50:46 2010''