3bqk - Revision history

OCA at 08:22, 19 January 2022

OCA — Wed, 19 Jan 2022 08:22:25 GMT

←Older revision		Revision as of 08:22, 19 January 2022
Line 1:		Line 1:

	==Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate==		==Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate==
-	<StructureSection load='3bqk' size='340' side='right' caption='[[3bqk]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3bqk' size='340' side='right'caption='[[3bqk]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3bqk]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BQK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3bqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BQK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bqi\|3bqi]], [[3bql\|3bql]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [~~http~~://pdbe.org/3bqk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3bqk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3bqk ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [https://pdbe.org/3bqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [https://www.ebi.ac.uk/pdbsum/3bqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bqk ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Plafa]]		[[Category: Plafa]]
	[[Category: Higgins, M K]]		[[Category: Higgins, M K]]

OCA at 07:46, 31 October 2018

OCA — Wed, 31 Oct 2018 07:46:31 GMT

←Older revision		Revision as of 07:46, 31 October 2018
Line 1:		Line 1:
		+
	==Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate==		==Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate==
	<StructureSection load='3bqk' size='340' side='right' caption='[[3bqk]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3bqk' size='340' side='right' caption='[[3bqk]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [http://pdbe.org/3bqk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [http://www.ebi.ac.uk/pdbsum/3bqk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [http://pdbe.org/3bqk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [http://www.ebi.ac.uk/pdbsum/3bqk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bqk ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/3bqk_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/3bqk_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:09, 8 February 2016

OCA — Mon, 08 Feb 2016 11:09:46 GMT

←Older revision		Revision as of 11:09, 8 February 2016
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [http://www.ebi.ac.uk/pdbsum/3bqk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [http://pdbe.org/3bqk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [http://www.ebi.ac.uk/pdbsum/3bqk PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bqk ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3bqk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:09, 20 January 2015

OCA — Tue, 20 Jan 2015 09:09:00 GMT

←Older revision		Revision as of 09:09, 20 January 2015
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Plafa]]		[[Category: Plafa]]
-	[[Category: Higgins, M K.]]	+	[[Category: Higgins, M K]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Chondroitin sulphate some]]		[[Category: Chondroitin sulphate some]]

OCA at 06:31, 10 October 2014

OCA — Fri, 10 Oct 2014 06:31:11 GMT

←Older revision		Revision as of 06:31, 10 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}~~	+	==Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate==
-	===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===	+	<StructureSection load='3bqk' size='340' side='right' caption='[[3bqk]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_18550531}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3bqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BQK FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bqi\|3bqi]], [[3bql\|3bql]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">var ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bqk RCSB], [http://www.ebi.ac.uk/pdbsum/3bqk PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/3bqk_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Adhesive PfEMP1 proteins are displayed on the surface of malaria-infected red blood cells. They play a critical role in the disease, tethering infected cells away from destruction by the spleen and causing many severe symptoms. A molecular understanding of how these domains maintain their binding properties while evading immune detection will be important in developing therapeutics. In malaria of pregnancy, domains from the var2csa-encoded PfEMP1 protein interact with chondroitin sulfate on the placenta surface. This causes accumulation of infected red blood cells, leading to placental inflammation and block of blood flow to the developing fetus. This is associated with maternal anemia, low birth weight, and premature delivery and can lead to the death of mother and child. Here I present the structure of the chondroitin sulfate-binding DBL3X domain from a var2csa-encoded PfEMP1 protein. The domain adopts a fold similar to malarial invasion proteins, with extensive loop insertions. One loop is flexible in the unliganded structure but observed in the presence of sulfate or disaccharide, where it completes a sulfate-binding site. This loop, and others surrounding this putative carbohydrate-binding site, are flexible and polymorphic, perhaps protecting the binding site from immune detection. This suggests a model for how the domain maintains ligand binding while evading the immune response and will guide future drug and vaccine development.

-	~~==About this Structure==~~	+	The structure of a chondroitin sulfate-binding domain important in placental malaria.,Higgins MK J Biol Chem. 2008 Aug 8;283(32):21842-6. Epub 2008 Jun 11. PMID:18550531<ref>PMID:18550531</ref>
-	~~[[3bqk]] is~~ a ~~1 chain structure~~. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3BQK OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:018550531</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Plafa]]
	[[Category: Higgins, M K.]]		[[Category: Higgins, M K.]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 09:46, 19 March 2014

OCA — Wed, 19 Mar 2014 09:46:43 GMT

←Older revision		Revision as of 09:46, 19 March 2014
Line 1:		Line 1:
-	[[Image:3bqk.png\|left\|200px]]
-
	{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}		{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}
-
	===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===		===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===
-
	{{ABSTRACT_PUBMED_18550531}}		{{ABSTRACT_PUBMED_18550531}}

	==About this Structure==		==About this Structure==
-	[[3bqk]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].	+	[[3bqk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:018550531</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018550531</ref><references group="xtra"/><references/>
-	~~[[Category: Plasmodium falciparum]]~~	+
	[[Category: Higgins, M K.]]		[[Category: Higgins, M K.]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA: Protected "3bqk" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 18:39:27 GMT

Protected "3bqk" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:39, 7 January 2013

OCA at 18:39, 7 January 2013

OCA — Mon, 07 Jan 2013 18:39:24 GMT

←Older revision		Revision as of 18:39, 7 January 2013
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-	{{Seed}}
	[[Image:3bqk.png\|left\|200px]]		[[Image:3bqk.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3bqk", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}		{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}

	===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===		===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18550531}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18550531 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18550531}}		{{ABSTRACT_PUBMED_18550531}}

	==About this Structure==		==About this Structure==
-	~~3BQK~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].	+	[[3bqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18550531~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018550531</ref><references group="xtra"/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Higgins, M K.]]		[[Category: Higgins, M K.]]
Line 32:		Line 20:
	[[Category: Pregnancy]]		[[Category: Pregnancy]]
	[[Category: Var2csa encoded pfemp1 protein]]		[[Category: Var2csa encoded pfemp1 protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:33:15 2009''

OCA at 19:33, 16 February 2009

OCA — Mon, 16 Feb 2009 19:33:17 GMT

←Older revision		Revision as of 19:33, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3BQK is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].	+	3BQK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].

	==Reference==		==Reference==
-	~~The structure of a chondroitin sulphate-binding domain important in placental malaria., Higgins MK, J Biol Chem. 2008 Jun 11;.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18550531 18550531]~~	+	<ref group="xtra">PMID:18550531</ref><references group="xtra"/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
-	[[Category: Single protein]]
	[[Category: Higgins, M K.]]		[[Category: Higgins, M K.]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
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	[[Category: Var2csa encoded pfemp1 protein]]		[[Category: Var2csa encoded pfemp1 protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon ~~Jul 28 02~~:26:~~50 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:33:15 2009''

OCA at 23:26, 27 July 2008

OCA — Sun, 27 Jul 2008 23:26:53 GMT

←Older revision		Revision as of 23:26, 27 July 2008
Line 1:		Line 1:
-	[[Image:3bqk.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:3bqk.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}		{{STRUCTURE_3bqk\| PDB=3bqk \| SCENE= }}

-	~~'''~~Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate~~'''~~	+	===Structure of a chondroitin sulphate binding DBL3X from a var2csa encoded PfEMP1 protein in complex with sulphate===


-	{{~~ABSTRACT_18550531~~}}	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18550531}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18550531 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18550531}}

	==About this Structure==		==About this Structure==
	3BQK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].		3BQK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BQK OCA].
		+
		+	==Reference==
		+	The structure of a chondroitin sulphate-binding domain important in placental malaria., Higgins MK, J Biol Chem. 2008 Jun 11;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18550531 18550531]
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Single protein]]		[[Category: Single protein]]
Line 26:		Line 34:
	[[Category: Var2csa encoded pfemp1 protein]]		[[Category: Var2csa encoded pfemp1 protein]]

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