3cqj - Revision history

OCA at 12:32, 30 August 2023

OCA — Wed, 30 Aug 2023 12:32:13 GMT

←Older revision		Revision as of 12:32, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='3cqj' size='340' side='right'caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3cqj' size='340' side='right'caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.04Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[3cqh\|3cqh]]~~, [[~~3cqi~~\|~~3cqi]], [[3cqk\|3cqk~~]]~~</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>ulaE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~562~~ "~~Bacillus coli~~" ~~Migula 1895])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [https://pdbe.org/3cqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [https://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqj ProSAT], [https://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [https://pdbe.org/3cqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [https://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqj ProSAT], [https://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ULAE_ECO57 ULAE_ECO57]] Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity).	+	[https://www.uniprot.org/uniprot/ULAE_ECO57 ULAE_ECO57] Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895]]~~	+	[[Category: Escherichia coli]]
-	~~[[Category: L-ribulose-5-phosphate 3-epimerase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Structural genomic]]~~	+	[[Category: Cygler M]]
-	[[Category: Cygler, M]]	+	[[Category: Matte A]]
-	[[Category: Matte, A]]	+	[[Category: Shi R]]
-	[[Category: Shi, R]]	+
-	~~[[Category: Bsgi]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Phosphate-binding motif]]~~	+
-	~~[[Category: Tim-barrel~~]]	+

OCA at 07:42, 2 February 2022

OCA — Wed, 02 Feb 2022 07:42:09 GMT

OCA at 19:19, 11 August 2016

OCA — Thu, 11 Aug 2016 19:19:16 GMT

←Older revision		Revision as of 19:19, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+==		==Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+==
	<StructureSection load='3cqj' size='340' side='right' caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3cqj' size='340' side='right' caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqh\|3cqh]], [[3cqi\|3cqi]], [[3cqk\|3cqk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqh\|3cqh]], [[3cqi\|3cqi]], [[3cqk\|3cqk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [http://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [http://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [http://pdbe.org/3cqj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [http://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqj ProSAT], [http://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ULAE_ECO57 ULAE_ECO57]] Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cqj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 30:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3cqj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 09:41, 20 January 2015

OCA — Tue, 20 Jan 2015 09:41:21 GMT

←Older revision		Revision as of 09:41, 20 January 2015
Line 33:		Line 33:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]
-	[[Category: ~~BSGI, Montreal-Kingston Bacterial~~ Structural ~~Genomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Cygler, M.]]	+	[[Category: Cygler, M]]
-	[[Category: Matte, A.]]	+	[[Category: Matte, A]]
-	[[Category: Shi, R.]]	+	[[Category: Shi, R]]
	[[Category: Bsgi]]		[[Category: Bsgi]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
-	[[Category: Montreal-kingston bacterial structural genomics initiative]]
	[[Category: Phosphate-binding motif]]		[[Category: Phosphate-binding motif]]
-	[[Category: Structural genomic]]
	[[Category: Tim-barrel]]		[[Category: Tim-barrel]]

OCA at 06:48, 10 October 2014

OCA — Fri, 10 Oct 2014 06:48:27 GMT

←Older revision		Revision as of 06:48, 10 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}~~	+	==Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+==
-	===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===	+	<StructureSection load='3cqj' size='340' side='right' caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>
-	~~{{ABSTRACT_PUBMED_18849419}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqh\|3cqh]], [[3cqi\|3cqi]], [[3cqk\|3cqk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [http://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [http://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Three catabolic enzymes, UlaD, UlaE, and UlaF, are involved in a pathway leading to fermentation of l-ascorbate under anaerobic conditions. UlaD catalyzes a beta-keto acid decarboxylation reaction to produce l-xylulose-5-phosphate, which undergoes successive epimerization reactions with UlaE (l-xylulose-5-phosphate 3-epimerase) and UlaF (l-ribulose-5-phosphate 4-epimerase), yielding d-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway. We describe here crystallographic studies of UlaE from Escherichia coli O157:H7 that complete the structural characterization of this pathway. UlaE has a triosephosphate isomerase (TIM) barrel fold and forms dimers. The active site is located at the C-terminal ends of the parallel beta-strands. The enzyme binds Zn(2+), which is coordinated by Glu155, Asp185, His211, and Glu251. We identified a phosphate-binding site formed by residues from the beta1/alpha1 loop and alpha3' helix in the N-terminal region. This site differs from the well-characterized phosphate-binding motif found in several TIM barrel superfamilies that is located at strands beta7 and beta8. The intrinsic flexibility of the active site region is reflected by two different conformations of loops forming part of the substrate-binding site. Based on computational docking of the l-xylulose 5-phosphate substrate to UlaE and structural similarities of the active site of this enzyme to the active sites of other epimerases, a metal-dependent epimerization mechanism for UlaE is proposed, and Glu155 and Glu251 are implicated as catalytic residues. Mutation and activity measurements for structurally equivalent residues in related epimerases supported this mechanistic proposal.

-	~~==About this~~ Structure==	+	Structure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel Fold.,Shi R, Pineda M, Ajamian E, Cui Q, Matte A, Cygler M J Bacteriol. 2008 Dec;190(24):8137-44. Epub 2008 Oct 10. PMID:18849419<ref>PMID:18849419</ref>
-	~~[[3cqj]] is a 2 chain structure with sequence~~ from ~~[http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3CQJ OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:018849419</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]

OCA at 09:14, 19 June 2013

OCA — Wed, 19 Jun 2013 09:14:21 GMT

←Older revision		Revision as of 09:14, 19 June 2013
Line 1:		Line 1:
-	[[Image:3cqj.png\|left\|200px]]
-
	{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}		{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}
-
	===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===		===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===
-
	{{ABSTRACT_PUBMED_18849419}}		{{ABSTRACT_PUBMED_18849419}}

	==About this Structure==		==About this Structure==
	[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA].		[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:018849419</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]

OCA: Protected "3cqj" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:41:24 GMT

Protected "3cqj" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:41, 7 January 2013

OCA at 21:41, 7 January 2013

OCA — Mon, 07 Jan 2013 21:41:22 GMT

←Older revision		Revision as of 21:41, 7 January 2013
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-	{{Seed}}
	[[Image:3cqj.png\|left\|200px]]		[[Image:3cqj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3cqj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}		{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}

	===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===		===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18849419}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18849419 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18849419}}		{{ABSTRACT_PUBMED_18849419}}

	==About this Structure==		==About this Structure==
-	~~3CQJ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA].	+	[[3cqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA].
-		+
-	~~==Reference==~~	+
-	Structure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel Fold., Shi R, Pineda M, Ajamian E, Cui Q, Matte A, Cygler M, J Bacteriol. 2008 Dec;190(24):8137-44. Epub 2008 Oct 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18849419 18849419]	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]
Line 36:		Line 21:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Tim-barrel]]		[[Category: Tim-barrel]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:50:54 2008''

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OCA — Fri, 05 Dec 2008 07:50:55 GMT

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	{{Seed}}		{{Seed}}
-	[[Image:3cqj.~~jpg~~\|left\|200px]]	+	[[Image:3cqj.png\|left\|200px]]

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	[[Category: Tim-barrel]]		[[Category: Tim-barrel]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Nov 27 13~~:35:14 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:50:54 2008''

OCA at 11:35, 27 November 2008

OCA — Thu, 27 Nov 2008 11:35:17 GMT

←Older revision		Revision as of 11:35, 27 November 2008
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3cqj.jpg\|left\|200px]]

-	The ~~entry 3cqj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3cqj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3cqj\| PDB=3cqj \| SCENE= }}

-	~~Authors: Shi, R., Matte, A., Cygler, M., Montreal~~-~~Kingston Bacterial Structural Genomics Initiative~~ (~~BSGI~~)	+	===Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+===

-	Description: Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug~~ 27 10:56:28 2008''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18849419}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18849419 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18849419}}
		+
		+	==About this Structure==
		+	3CQJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA].
		+
		+	==Reference==
		+	Structure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel Fold., Shi R, Pineda M, Ajamian E, Cui Q, Matte A, Cygler M, J Bacteriol. 2008 Dec;190(24):8137-44. Epub 2008 Oct 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18849419 18849419]
		+	[[Category: Escherichia coli]]
		+	[[Category: L-ribulose-5-phosphate 3-epimerase]]
		+	[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
		+	[[Category: Cygler, M.]]
		+	[[Category: Matte, A.]]
		+	[[Category: Shi, R.]]
		+	[[Category: Bsgi]]
		+	[[Category: Isomerase]]
		+	[[Category: Montreal-kingston bacterial structural genomics initiative]]
		+	[[Category: Phosphate-binding motif]]
		+	[[Category: Structural genomic]]
		+	[[Category: Tim-barrel]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 27 13:35:14 2008''

←Older revision		Revision as of 07:42, 2 February 2022
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	==Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+==		==Crystal Structure of L-xylulose-5-phosphate 3-epimerase UlaE (form B) complex with Zn2+==
-	<StructureSection load='3cqj' size='340' side='right' caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>	+	<StructureSection load='3cqj' size='340' side='right'caption='[[3cqj]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3cqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CQJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3cqh\|3cqh]], [[3cqi\|3cqi]], [[3cqk\|3cqk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3cqh\|3cqh]], [[3cqi\|3cqi]], [[3cqk\|3cqk]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaE ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-ribulose-5-phosphate_3-epimerase L-ribulose-5-phosphate 3-epimerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.22 5.1.3.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [~~http~~://pdbe.org/3cqj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqj ProSAT], [~~http~~://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cqj OCA], [https://pdbe.org/3cqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cqj RCSB], [https://www.ebi.ac.uk/pdbsum/3cqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cqj ProSAT], [https://www.topsan.org/Proteins/BSGI/3cqj TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ULAE_ECO57 ULAE_ECO57]] Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity).	+	[[https://www.uniprot.org/uniprot/ULAE_ECO57 ULAE_ECO57]] Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/3cqj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: L-ribulose-5-phosphate 3-epimerase]]		[[Category: L-ribulose-5-phosphate 3-epimerase]]
		+	[[Category: Large Structures]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Cygler, M]]		[[Category: Cygler, M]]