3ejw - Revision history

OCA at 13:05, 30 August 2023

OCA — Wed, 30 Aug 2023 13:05:54 GMT

←Older revision		Revision as of 13:05, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='3ejw' size='340' side='right'caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3ejw' size='340' side='right'caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_9930 Atcc 9930~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EJW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PAV:(2R,4S)~~-~~2-METHYL-2~~,~~3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;'>[[1tjy\|1tjy]]~~, ~~[[1jx6\|1jx6]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [https://pdbe.org/3ejw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [https://www.ebi.ac.uk/pdbsum/3ejw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [https://pdbe.org/3ejw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [https://www.ebi.ac.uk/pdbsum/3ejw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejw ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q926H7_RHIME Q926H7_RHIME]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 9930]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~McAuley, J R~~]]	+	[[Category: Sinorhizobium meliloti]]
-	[[Category: ~~Miller, S T~~]]	+	[[Category: McAuley JR]]
-	[[Category: ~~Pereira, C~~]]	+	[[Category: Miller ST]]
-	[[Category: ~~Taga, M E~~]]	+	[[Category: Pereira C]]
-	[[Category: ~~Xavier, K B~~]]	+	[[Category: Taga ME]]
-	[[Category: ~~Periplasmic binding protein]]~~	+	[[Category: Xavier KB]]
-	~~[[Category: Plasmid]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 11:51, 16 February 2022

OCA — Wed, 16 Feb 2022 11:51:36 GMT

←Older revision		Revision as of 11:51, 16 February 2022
Line 1:		Line 1:

	==Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB==		==Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB==
-	<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3ejw' size='340' side='right'caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_9930 Atcc 9930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_9930 Atcc 9930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EJW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tjy\|1tjy]], [[1jx6\|1jx6]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [~~http~~://pdbe.org/3ejw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ejw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [https://pdbe.org/3ejw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [https://www.ebi.ac.uk/pdbsum/3ejw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 9930]]		[[Category: Atcc 9930]]
		+	[[Category: Large Structures]]
	[[Category: McAuley, J R]]		[[Category: McAuley, J R]]
	[[Category: Miller, S T]]		[[Category: Miller, S T]]

OCA at 06:31, 4 April 2018

OCA — Wed, 04 Apr 2018 06:31:14 GMT

←Older revision		Revision as of 06:31, 4 April 2018
Line 1:		Line 1:
		+
	==Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB==		==Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB==
	<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [http://pdbe.org/3ejw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [http://www.ebi.ac.uk/pdbsum/3ejw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [http://pdbe.org/3ejw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [http://www.ebi.ac.uk/pdbsum/3ejw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ejw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/3ejw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/3ejw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 38:		Line 39:
	[[Category: Xavier, K B]]		[[Category: Xavier, K B]]
	[[Category: Periplasmic binding protein]]		[[Category: Periplasmic binding protein]]
		+	[[Category: Plasmid]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 09:46, 7 February 2016

OCA — Sun, 07 Feb 2016 09:46:33 GMT

←Older revision		Revision as of 09:46, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sinorhizobium_meliloti Sinorhizobium meliloti~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_9930 Atcc 9930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EJW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ~~Sinorhizobium meliloti~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ATCC 9930])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [http://www.ebi.ac.uk/pdbsum/3ejw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [http://pdbe.org/3ejw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [http://www.ebi.ac.uk/pdbsum/3ejw PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ejw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ejw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sinorhizobium meliloti~~]]	+	[[Category: Atcc 9930]]
	[[Category: McAuley, J R]]		[[Category: McAuley, J R]]
	[[Category: Miller, S T]]		[[Category: Miller, S T]]

OCA at 13:33, 19 November 2014

OCA — Wed, 19 Nov 2014 13:33:42 GMT

←Older revision		Revision as of 13:33, 19 November 2014
Line 1:		Line 1:
-	[[~~Image:~~3ejw.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB==
		+	<StructureSection load='3ejw' size='340' side='right' caption='[[3ejw]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ejw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EJW FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[1jx6\|1jx6]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AitB, RB0590, SM_b21016, SMb21016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ejw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ejw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ejw RCSB], [http://www.ebi.ac.uk/pdbsum/3ejw PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/3ejw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Many bacterial species respond to the quorum-sensing signal autoinducer-2 (AI-2) by regulating different niche-specific genes. Here, we show that Sinorhizobium meliloti, a plant symbiont lacking the gene for the AI-2 synthase, while not capable of producing AI-2 can nonetheless respond to AI-2 produced by other species. We demonstrate that S. meliloti has a periplasmic binding protein that binds AI-2. The crystal structure of this protein (here named SmlsrB) with its ligand reveals that it binds (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (R-THMF), the identical AI-2 isomer recognized by LsrB of Salmonella typhimurium. The gene encoding SmlsrB is in an operon with orthologues of the lsr genes required for AI-2 internalization in enteric bacteria. Accordingly, S. meliloti internalizes exogenous AI-2, and mutants in this operon are defective in AI-2 internalization. S. meliloti does not gain a metabolic benefit from internalizing AI-2, suggesting that AI-2 functions as a signal in S. meliloti. Furthermore, S. meliloti can completely eliminate the AI-2 secreted by Erwinia carotovora, a plant pathogen shown to use AI-2 to regulate virulence. Our findings suggest that S. meliloti is capable of 'eavesdropping' on the AI-2 signalling of other species and interfering with AI-2-regulated behaviours such as virulence.

-	~~{{STRUCTURE_3ejw\| PDB=3ejw \| SCENE= }}~~	+	Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria.,Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST Mol Microbiol. 2008 Dec;70(5):1223-35. PMID:18990189<ref>PMID:18990189</ref>

-	~~===Crystal Structure~~ of the ~~Sinorhizobium meliloti AI-2 receptor, SmLsrB===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18990189}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3ejw]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA].~~	+	</StructureSection>
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
-	[[Category: McAuley, J R.]]	+	[[Category: McAuley, J R]]
-	[[Category: Miller, S T.]]	+	[[Category: Miller, S T]]
-	[[Category: Pereira, C.]]	+	[[Category: Pereira, C]]
-	[[Category: Taga, M E.]]	+	[[Category: Taga, M E]]
-	[[Category: Xavier, K B.]]	+	[[Category: Xavier, K B]]
	[[Category: Periplasmic binding protein]]		[[Category: Periplasmic binding protein]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA: Protected "3ejw" [edit=sysop:move=sysop]

OCA — Wed, 09 Jan 2013 09:01:42 GMT

Protected "3ejw" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:01, 9 January 2013

OCA at 09:01, 9 January 2013

OCA — Wed, 09 Jan 2013 09:01:40 GMT

←Older revision		Revision as of 09:01, 9 January 2013
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-	{{Seed}}
	[[Image:3ejw.png\|left\|200px]]		[[Image:3ejw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ejw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ejw\| PDB=3ejw \| SCENE= }}		{{STRUCTURE_3ejw\| PDB=3ejw \| SCENE= }}

	===Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB===		===Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18990189}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18990189 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18990189}}		{{ABSTRACT_PUBMED_18990189}}

	==About this Structure==		==About this Structure==
-	~~3EJW~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA].	+	[[3ejw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA].
-		+
-	~~==Reference==~~	+
-	Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria., Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST, Mol Microbiol. 2008 Dec;70(5):1223-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18990189 18990189]	+
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
	[[Category: McAuley, J R.]]		[[Category: McAuley, J R.]]
Line 31:		Line 16:
	[[Category: Xavier, K B.]]		[[Category: Xavier, K B.]]
	[[Category: Periplasmic binding protein]]		[[Category: Periplasmic binding protein]]
-	[[Category: Plasmid]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:47:13 2008''

OCA at 13:47, 10 December 2008

OCA — Wed, 10 Dec 2008 13:47:13 GMT

←Older revision		Revision as of 13:47, 10 December 2008
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	{{Seed}}		{{Seed}}
-	[[Image:3ejw.~~jpg~~\|left\|200px]]	+	[[Image:3ejw.png\|left\|200px]]

	<!--		<!--
Line 25:		Line 25:
	Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria., Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST, Mol Microbiol. 2008 Dec;70(5):1223-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18990189 18990189]		Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria., Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST, Mol Microbiol. 2008 Dec;70(5):1223-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18990189 18990189]
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
-	[[Category: ~~Pdbx_ordinal=~~, ~~<PDBx~~:~~audit_author~~.]]	+	[[Category: McAuley, J R.]]
		+	[[Category: Miller, S T.]]
		+	[[Category: Pereira, C.]]
		+	[[Category: Taga, M E.]]
		+	[[Category: Xavier, K B.]]
	[[Category: Periplasmic binding protein]]		[[Category: Periplasmic binding protein]]
	[[Category: Plasmid]]		[[Category: Plasmid]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri~~ Dec ~~5 09~~:40:46 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:47:13 2008''

OCA at 07:40, 5 December 2008

OCA — Fri, 05 Dec 2008 07:40:47 GMT

←Older revision		Revision as of 07:40, 5 December 2008
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ejw.jpg\|left\|200px]]

-	The ~~entry 3ejw~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ejw", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ejw\| PDB=3ejw \| SCENE= }}

-	~~Authors: Miller~~, ~~S.T., McAuley, J.R., Pereira, C., Xavier, K.B., Taga, M.E.~~	+	===Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB===

-	Description: Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, AitB

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 15 14~~:05:38 2008''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18990189}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18990189 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18990189}}
		+
		+	==About this Structure==
		+	3EJW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EJW OCA].
		+
		+	==Reference==
		+	Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria., Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST, Mol Microbiol. 2008 Dec;70(5):1223-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18990189 18990189]
		+	[[Category: Sinorhizobium meliloti]]
		+	[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
		+	[[Category: Periplasmic binding protein]]
		+	[[Category: Plasmid]]
		+	[[Category: Signaling protein]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:40:46 2008''

OCA at 12:05, 15 October 2008

OCA — Wed, 15 Oct 2008 12:05:39 GMT

←Older revision		Revision as of 12:05, 15 October 2008
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3ejw is ON HOLD	+	The entry 3ejw is ON HOLD until Paper Publication

	Authors: Miller, S.T., McAuley, J.R., Pereira, C., Xavier, K.B., Taga, M.E.		Authors: Miller, S.T., McAuley, J.R., Pereira, C., Xavier, K.B., Taga, M.E.
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	Description: Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, AitB		Description: Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, AitB

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~8 09~~:19:57 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 14:05:38 2008''