3eqq - Revision history

OCA at 00:23, 28 December 2023

OCA — Thu, 28 Dec 2023 00:23:39 GMT

←Older revision		Revision as of 00:23, 28 December 2023
Line 3:		Line 3:
	<StructureSection load='3eqq' size='340' side='right'caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3eqq' size='340' side='right'caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>~~, ~~<scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>bnzA, todC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~303~~ "~~Bacillus fluorescens putidus~~" ~~Flugge 1886]), bnzB, todC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=303 "Bacillus fluorescens putidus" Flugge 1886]~~)~~</td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:</~~b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [https://pdbe.org/3eqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [https://www.ebi.ac.uk/pdbsum/3eqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eqq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [https://pdbe.org/3eqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [https://www.ebi.ac.uk/pdbsum/3eqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eqq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~BNZA_PSEPU BNZA_PSEPU]~~] Catalyzes both the oxidation of benzene and toluene~~. [[https://www.uniprot.org/uniprot/BNZB_PSEPU BNZB_PSEPU]] Catalyzes both the oxidation of benzene and toluene. The beta subunit may be responsible for the substrate specificity of the enzyme~~.	+	[https://www.uniprot.org/uniprot/BNZA_PSEP1 BNZA_PSEP1] Catalyzes both the oxidation of benzene and toluene.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus fluorescens putidus flugge 1886]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Toluene dioxygenase~~]]	+	[[Category: Pseudomonas putida]]
-	[[Category: Brown~~, E N~~]]	+	[[Category: Brown EN]]
-	[[Category: Eklund, H]]	+	[[Category: Eklund H]]
-	[[Category: Friemann, R]]	+	[[Category: Friemann R]]
-	[[Category: Gibson~~, D T~~]]	+	[[Category: Gibson DT]]
-	[[Category: Lee, K]]	+	[[Category: Lee K]]
-	[[Category: Ramaswamy, S]]	+	[[Category: Ramaswamy S]]
-	~~[[Category: 2fe-2]]~~	+
-	~~[[Category: Apo-structure]]~~	+
-	~~[[Category: Aromatic hydrocarbons catabolism]]~~	+
-	~~[[Category: Dioxygenase]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Iron-sulfur]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Rieske iron sulfur binding protein~~]]	+

OCA at 09:13, 23 February 2022

OCA — Wed, 23 Feb 2022 09:13:52 GMT

←Older revision		Revision as of 09:13, 23 February 2022
Line 1:		Line 1:

	==Apo Toluene 2,3-Dioxygenase==		==Apo Toluene 2,3-Dioxygenase==
-	<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='3eqq' size='340' side='right'caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886]), bnzB, todC2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886]), bnzB, todC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [~~http~~://pdbe.org/3eqq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3eqq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3eqq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [https://pdbe.org/3eqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [https://www.ebi.ac.uk/pdbsum/3eqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eqq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BNZA_PSEPU BNZA_PSEPU]] Catalyzes both the oxidation of benzene and toluene. [[~~http~~://www.uniprot.org/uniprot/BNZB_PSEPU BNZB_PSEPU]] Catalyzes both the oxidation of benzene and toluene. The beta subunit may be responsible for the substrate specificity of the enzyme.	+	[[https://www.uniprot.org/uniprot/BNZA_PSEPU BNZA_PSEPU]] Catalyzes both the oxidation of benzene and toluene. [[https://www.uniprot.org/uniprot/BNZB_PSEPU BNZB_PSEPU]] Catalyzes both the oxidation of benzene and toluene. The beta subunit may be responsible for the substrate specificity of the enzyme.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus fluorescens putidus flugge 1886]]		[[Category: Bacillus fluorescens putidus flugge 1886]]
		+	[[Category: Large Structures]]
	[[Category: Toluene dioxygenase]]		[[Category: Toluene dioxygenase]]
	[[Category: Brown, E N]]		[[Category: Brown, E N]]

OCA at 19:15, 24 January 2018

OCA — Wed, 24 Jan 2018 19:15:54 GMT

←Older revision		Revision as of 19:15, 24 January 2018
Line 1:		Line 1:
		+
	==Apo Toluene 2,3-Dioxygenase==		==Apo Toluene 2,3-Dioxygenase==
	<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://pdbe.org/3eqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://pdbe.org/3eqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3eqq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/3eqq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/3eqq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 42:		Line 43:
	[[Category: Lee, K]]		[[Category: Lee, K]]
	[[Category: Ramaswamy, S]]		[[Category: Ramaswamy, S]]
		+	[[Category: 2fe-2]]
	[[Category: Apo-structure]]		[[Category: Apo-structure]]
	[[Category: Aromatic hydrocarbons catabolism]]		[[Category: Aromatic hydrocarbons catabolism]]

OCA at 14:25, 7 February 2016

OCA — Sun, 07 Feb 2016 14:25:55 GMT

←Older revision		Revision as of 14:25, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_putida Pseudomonas putida~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 ~~Pseudomonas putida~~]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 ~~Pseudomonas putida~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://pdbe.org/3eqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BNZA_PSEPU BNZA_PSEPU]] Catalyzes both the oxidation of benzene and toluene. [[http://www.uniprot.org/uniprot/BNZB_PSEPU BNZB_PSEPU]] Catalyzes both the oxidation of benzene and toluene. The beta subunit may be responsible for the substrate specificity of the enzyme.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eqq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3eqq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas putida~~]]	+	[[Category: Bacillus fluorescens putidus flugge 1886]]
	[[Category: Toluene dioxygenase]]		[[Category: Toluene dioxygenase]]
	[[Category: Brown, E N]]		[[Category: Brown, E N]]

OCA at 10:05, 20 January 2015

OCA — Tue, 20 Jan 2015 10:05:24 GMT

←Older revision		Revision as of 10:05, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Toluene dioxygenase]]		[[Category: Toluene dioxygenase]]
-	[[Category: Brown, E N.]]	+	[[Category: Brown, E N]]
-	[[Category: Eklund, H.]]	+	[[Category: Eklund, H]]
-	[[Category: Friemann, R.]]	+	[[Category: Friemann, R]]
-	[[Category: Gibson, D T.]]	+	[[Category: Gibson, D T]]
	[[Category: Lee, K]]		[[Category: Lee, K]]
-	[[Category: Ramaswamy, S.]]	+	[[Category: Ramaswamy, S]]
	[[Category: Apo-structure]]		[[Category: Apo-structure]]
	[[Category: Aromatic hydrocarbons catabolism]]		[[Category: Aromatic hydrocarbons catabolism]]

OCA at 12:13, 29 September 2014

OCA — Mon, 29 Sep 2014 12:13:59 GMT

←Older revision		Revision as of 12:13, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3eqq.~~png~~\|~~left~~\|200px]]	+	==Apo Toluene 2,3-Dioxygenase==
		+	<StructureSection load='3eqq' size='340' side='right' caption='[[3eqq]], [[Resolution\|resolution]] 3.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EQQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef6\|3ef6]], [[3dqy\|3dqy]], [[3en1\|3en1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">bnzA, todC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida]), bnzB, todC2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Toluene_dioxygenase Toluene dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.11 1.14.12.11] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eqq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3eqq RCSB], [http://www.ebi.ac.uk/pdbsum/3eqq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/3eqq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial Rieske non-heme iron oxygenases catalyze the initial hydroxylation of aromatic hydrocarbon substrates. The structures of all three components of one such system, the toluene 2,3-dioxygenase system, have now been determined. This system consists of a reductase, a ferredoxin and a terminal dioxygenase. The dioxygenase, which was cocrystallized with toluene, is a heterohexamer containing a catalytic and a structural subunit. The catalytic subunit contains a Rieske [2Fe-2S] cluster and mononuclear iron at the active site. This iron is not strongly bound and is easily removed during enzyme purification. The structures of the enzyme with and without mononuclear iron demonstrate that part of the structure is flexible in the absence of iron. The orientation of the toluene substrate in the active site is consistent with the regiospecificity of oxygen incorporation seen in the product formed. The ferredoxin is Rieske type and contains a [2Fe-2S] cluster close to the protein surface. The reductase belongs to the glutathione reductase family of flavoenzymes and consists of three domains: an FAD-binding domain, an NADH-binding domain and a C-terminal domain. A model for electron transfer from NADH via FAD in the reductase and the ferredoxin to the terminal active-site mononuclear iron of the dioxygenase is proposed.

-	~~{{STRUCTURE_3eqq\| PDB=3eqq \| SCENE= }}~~	+	Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.,Friemann R, Lee K, Brown EN, Gibson DT, Eklund H, Ramaswamy S Acta Crystallogr D Biol Crystallogr. 2009 Jan;65(Pt 1):24-33. Epub 2008, Dec 18. PMID:19153463<ref>PMID:19153463</ref>

-	~~===Apo Toluene 2~~,~~3-Dioxygenase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19153463}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3eqq]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_putida Pseudomonas putida]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019153463<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pseudomonas putida]]		[[Category: Pseudomonas putida]]
	[[Category: Toluene dioxygenase]]		[[Category: Toluene dioxygenase]]

OCA: Protected "3eqq" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 11:27:45 GMT

Protected "3eqq" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:27, 21 October 2012

OCA at 11:27, 21 October 2012

OCA — Sun, 21 Oct 2012 11:27:42 GMT

←Older revision		Revision as of 11:27, 21 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3eqq.png\|left\|200px]]

-	~~The entry~~ 3eqq ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3eqq\| PDB=3eqq \| SCENE= }}

-	~~Authors: Friemann~~, ~~R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S.~~	+	===Apo Toluene 2,3-Dioxygenase===

-	~~Description: Apo Toluene 2,3-Dioxygenase~~	+	{{ABSTRACT_PUBMED_19153463}}

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Oct 15 14~~:06:~~28 2008''~~	+	==About this Structure==
		+	[[3eqq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQQ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:019153463</ref><references group="xtra"/>
		+	[[Category: Pseudomonas putida]]
		+	[[Category: Toluene dioxygenase]]
		+	[[Category: Brown, E N.]]
		+	[[Category: Eklund, H.]]
		+	[[Category: Friemann, R.]]
		+	[[Category: Gibson, D T.]]
		+	[[Category: Lee, K]]
		+	[[Category: Ramaswamy, S.]]
		+	[[Category: Apo-structure]]
		+	[[Category: Aromatic hydrocarbons catabolism]]
		+	[[Category: Dioxygenase]]
		+	[[Category: Iron]]
		+	[[Category: Iron-sulfur]]
		+	[[Category: Metal-binding]]
		+	[[Category: Nad]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Rieske iron sulfur binding protein]]

OCA at 12:06, 15 October 2008

OCA — Wed, 15 Oct 2008 12:06:29 GMT

←Older revision		Revision as of 12:06, 15 October 2008
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3eqq is ON HOLD	+	The entry 3eqq is ON HOLD until Paper Publication

	Authors: Friemann, R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S.		Authors: Friemann, R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S.
Line 7:		Line 7:
	Description: Apo Toluene 2,3-Dioxygenase		Description: Apo Toluene 2,3-Dioxygenase

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~8 09~~:21:37 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 14:06:28 2008''

OCA: New page: '''Unreleased structure''' The entry 3eqq is ON HOLD Authors: Friemann, R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S. Description: Apo Toluene 2,3-Dioxygenase ''Pag...

OCA — Wed, 08 Oct 2008 07:21:37 GMT

New page: '''Unreleased structure''' The entry 3eqq is ON HOLD Authors: Friemann, R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S. Description: Apo Toluene 2,3-Dioxygenase ''Pag...

New page

'''Unreleased structure'''

The entry 3eqq is ON HOLD

Authors: Friemann, R., Lee, K, Brown, E.N., Gibson, D.T., Eklund, H., Ramaswamy, S.

Description: Apo Toluene 2,3-Dioxygenase

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:21:37 2008''