3esa - Revision history

OCA at 15:23, 1 November 2023

OCA — Wed, 01 Nov 2023 15:23:05 GMT

←Older revision		Revision as of 15:23, 1 November 2023
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	<StructureSection load='3esa' size='340' side='right'caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3esa' size='340' side='right'caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ESA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_vanettenii Fusarium vanettenii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ESA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ef3\|3ef3]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [https://pdbe.org/3esa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [https://www.ebi.ac.uk/pdbsum/3esa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [https://pdbe.org/3esa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [https://www.ebi.ac.uk/pdbsum/3esa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CUTI1_FUSSO CUTI1_FUSSO]~~] Catalyzes the hydrolysis of cutin, a ~~polyester~~ that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of ~~the~~ fungal infection.	+	[https://www.uniprot.org/uniprot/CUTI1_FUSVN CUTI1_FUSVN] Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:18658138, PubMed:8286366, PubMed:8555209, PubMed:19810726). Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (Ref.4).<ref>PMID:18658138</ref> <ref>PMID:19810726</ref> <ref>PMID:8286366</ref> <ref>PMID:8555209</ref> [PROSITE-ProRule:PRU10109]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cutinase~~]]	+	[[Category: Fusarium vanettenii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gros, P]]	+	[[Category: Gros P]]
-	[[Category: Lutz, M]]	+	[[Category: Lutz M]]
-	[[Category: Mannie~~, J P.B A~~]]	+	[[Category: Mannie JPBA]]
-	[[Category: Rutten, L]]	+	[[Category: Rutten L]]
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Protein-metallopincer complex]]~~	+
-	~~[[Category: Secreted]]~~	+
-	~~[[Category: Serine esterase~~]]	+

OCA at 07:36, 10 November 2021

OCA — Wed, 10 Nov 2021 07:36:22 GMT

←Older revision		Revision as of 07:36, 10 November 2021
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	<StructureSection load='3esa' size='340' side='right'caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3esa' size='340' side='right'caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3ESA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ESA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ef3\|3ef3]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [~~http~~://pdbe.org/3esa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3esa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [https://pdbe.org/3esa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [https://www.ebi.ac.uk/pdbsum/3esa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.	+	[[https://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Cutinase]]		[[Category: Cutinase]]
-	[[Category: Fusso]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gros, P]]		[[Category: Gros, P]]

OCA at 10:24, 9 September 2020

OCA — Wed, 09 Sep 2020 10:24:52 GMT

←Older revision		Revision as of 10:24, 9 September 2020
Line 1:		Line 1:

	==cut-1b; NCN-Pt-Pincer-Cutinase Hybrid==		==cut-1b; NCN-Pt-Pincer-Cutinase Hybrid==
-	<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3esa' size='340' side='right'caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ESA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3ESA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://pdbe.org/3esa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://pdbe.org/3esa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Cutinase\|Cutinase]]	+	*[[Cutinase 3D structures\|Cutinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Cutinase]]		[[Category: Cutinase]]
	[[Category: Fusso]]		[[Category: Fusso]]
		+	[[Category: Large Structures]]
	[[Category: Gros, P]]		[[Category: Gros, P]]
	[[Category: Lutz, M]]		[[Category: Lutz, M]]

OCA at 21:59, 2 December 2018

OCA — Sun, 02 Dec 2018 21:59:00 GMT

←Older revision		Revision as of 21:59, 2 December 2018
Line 1:		Line 1:
		+
	==cut-1b; NCN-Pt-Pincer-Cutinase Hybrid==		==cut-1b; NCN-Pt-Pincer-Cutinase Hybrid==
	<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://pdbe.org/3esa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://pdbe.org/3esa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3esa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/3esa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/3esa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:57, 9 February 2016

OCA — Tue, 09 Feb 2016 11:57:26 GMT

←Older revision		Revision as of 11:57, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nectria_haematococca_mpvi Nectria haematococca mpvi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ESA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusso Fusso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ESA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://pdbe.org/3esa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3esa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3esa" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Cutinase]]		[[Category: Cutinase]]
-	[[Category: ~~Nectria haematococca mpvi~~]]	+	[[Category: Fusso]]
	[[Category: Gros, P]]		[[Category: Gros, P]]
	[[Category: Lutz, M]]		[[Category: Lutz, M]]

OCA at 06:39, 25 December 2014

OCA — Thu, 25 Dec 2014 06:39:44 GMT

←Older revision		Revision as of 06:39, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CUTI1_FUSSO CUTI1_FUSSO]] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infection.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 14:04, 18 December 2014

OCA — Thu, 18 Dec 2014 14:04:10 GMT

←Older revision		Revision as of 14:04, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3esa\| PDB=3esa \| SCENE= }}~~	+	==cut-1b; NCN-Pt-Pincer-Cutinase Hybrid==
-	===cut-1b; NCN-Pt-Pincer-Cutinase Hybrid===	+	<StructureSection load='3esa' size='340' side='right' caption='[[3esa]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	{~~{ABSTRACT_PUBMED_19219875}~~}	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ESA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NXC:(2,6-BIS[(DIMETHYLAMINO-KAPPAN)METHYL]-4-{3-[(S)-ETHOXY(4-NITROPHENOXY)PHOSPHORYL]PROPYL}PHENYL-KAPPAC~1~)(CHLORO)PLATINUM(2+)'>NXC</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ef3\|3ef3]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cutinase Cutinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.74 3.1.1.74] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3esa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3esa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3esa RCSB], [http://www.ebi.ac.uk/pdbsum/3esa PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/3esa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The first crystal structures of lipases that have been covalently modified through site-selective inhibition by different organometallic phosphonate-pincer-metal complexes are described. Two ECE-pincer-type d(8)-metal complexes, that is, platinum (1) or palladium (2) with phosphonate esters (ECE = [(EtO)-(O=)P(-O-C(6)H(4)-(NO(2))-4)(-C(3)H(6)-4-(C(6)H(2)-(CH(2)E)(2))](-) ; E = NMe(2) or SMe) were introduced prior to crystallization and have been shown to bind selectively to the Ser(120) residue in the active site of the lipase cutinase to give cut-1 (platinum) or cut-2 (palladium) hybrids. For all five presented crystal structures, the ECE-pincer-platinum or -palladium head group sticks out of the cutinase molecule and is exposed to the solvent. Depending on the nature of the ECE-pincer-metal head group, the ECE-pincer-platinum and -palladium guests occupy different pockets in the active site of cutinase, with concomitant different stereochemistries on the phosphorous atom for the cut-1 (S(P)) and cut-2 (R(P)) structures. When cut-1 was crystallized under halide-poor conditions, a novel metal-induced dimeric structure was formed between two cutinase-bound pincer-platinum head groups, which are interconnected through a single mu-Cl bridge. This halide-bridged metal dimer shows that coordination chemistry is possible with protein-modified pincer-metal complexes. Furthermore, we could use NCN-pincer-platinum complex 1 as site-selective tool for the phasing of raw protein diffraction data, which shows the potential use of pincer-platinum complex 1 as a heavy-atom derivative in protein crystallography.

-	~~==About this Structure==~~	+	Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids.,Rutten L, Wieczorek B, Mannie JP, Kruithof CA, Dijkstra HP, Egmond MR, Lutz M, Klein Gebbink RJ, Gros P, van Koten G Chemistry. 2009;15(17):4270-80. PMID:19219875<ref>PMID:19219875</ref>
-	~~[[3esa]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:019219875</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Cutinase\|Cutinase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cutinase]]		[[Category: Cutinase]]
	[[Category: Nectria haematococca mpvi]]		[[Category: Nectria haematococca mpvi]]
-	[[Category: Gros, P.]]	+	[[Category: Gros, P]]
-	[[Category: Lutz, M.]]	+	[[Category: Lutz, M]]
-	[[Category: Mannie, J P.B A.]]	+	[[Category: Mannie, J P.B A]]
-	[[Category: Rutten, L.]]	+	[[Category: Rutten, L]]
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 09:23, 27 March 2013

OCA — Wed, 27 Mar 2013 09:23:18 GMT

←Older revision		Revision as of 09:23, 27 March 2013
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-	[[Image:3esa.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3esa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3esa\| PDB=3esa \| SCENE= }}		{{STRUCTURE_3esa\| PDB=3esa \| SCENE= }}
-
	===cut-1b; NCN-Pt-Pincer-Cutinase Hybrid===		===cut-1b; NCN-Pt-Pincer-Cutinase Hybrid===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19219875}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19219875 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19219875}}		{{ABSTRACT_PUBMED_19219875}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019219875</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019219875</ref><references group="xtra"/><references/>
	[[Category: Cutinase]]		[[Category: Cutinase]]
	[[Category: Nectria haematococca mpvi]]		[[Category: Nectria haematococca mpvi]]

OCA: Protected "3esa" [edit=sysop:move=sysop]

OCA — Thu, 26 May 2011 11:46:01 GMT

Protected "3esa" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:46, 26 May 2011

OCA at 11:45, 26 May 2011

OCA — Thu, 26 May 2011 11:45:58 GMT

←Older revision		Revision as of 11:45, 26 May 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3esa.png\|left\|200px]]

-	The ~~entry 3esa~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3esa", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3esa\| PDB=3esa \| SCENE= }}

-	~~Authors: Rutten, L., Wieczorek, B., Mannie, J.P.B.A., Kruithof, C.A., Dijkstra, H.P., Egmond, M.R., Lutz, M., van Koten, G., Gros, P., Klein Gebbink, R.J.M.~~	+	===cut-1b; NCN-Pt-Pincer-Cutinase Hybrid===

-	Description: cut-1b; NCN-Pt-Pincer-Cutinase Hybrid

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Oct 15 14~~:06:~~42 2008''~~	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19219875}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19219875 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19219875}}
		+
		+	==About this Structure==
		+	[[3esa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nectria_haematococca_mpvi Nectria haematococca mpvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ESA OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:019219875</ref><references group="xtra"/>
		+	[[Category: Cutinase]]
		+	[[Category: Nectria haematococca mpvi]]
		+	[[Category: Gros, P.]]
		+	[[Category: Lutz, M.]]
		+	[[Category: Mannie, J P.B A.]]
		+	[[Category: Rutten, L.]]
		+	[[Category: Glycoprotein]]
		+	[[Category: Hydrolase]]
		+	[[Category: Protein-metallopincer complex]]
		+	[[Category: Secreted]]
		+	[[Category: Serine esterase]]