3euh - Revision history

OCA at 00:24, 28 December 2023

OCA — Thu, 28 Dec 2023 00:24:31 GMT

←Older revision		Revision as of 00:24, 28 December 2023
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	<StructureSection load='3euh' size='340' side='right'caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3euh' size='340' side='right'caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~] and [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EUH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EUH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GLY:GLYCINE'>GLY</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3euj\|3euj]], [[3euk\|3euk]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [https://pdbe.org/3euh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [https://www.ebi.ac.uk/pdbsum/3euh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3euh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [https://pdbe.org/3euh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [https://www.ebi.ac.uk/pdbsum/3euh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3euh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> [[https://www.uniprot.org/uniprot/Q6ITT5_ECOLX Q6ITT5_ECOLX]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.[HAMAP-Rule:MF_01802]	+	[https://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ha~~, N C~~]]	+	[[Category: Ha NC]]
-	[[Category: Ku, B]]	+	[[Category: Ku B]]
-	[[Category: Oh~~, B H~~]]	+	[[Category: Oh BH]]
-	[[Category: Suh~~, M K~~]]	+	[[Category: Suh MK]]
-	[[Category: Woo~~, J S]]~~	+	[[Category: Woo JS]]
-	~~[[Category: Calcium]]~~	+
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Cell division]]~~	+
-	~~[[Category: Chromosome condensation]]~~	+
-	~~[[Category: Chromosome partition]]~~	+
-	~~[[Category: Condensin]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Dna condensation]]~~	+
-	~~[[Category: Kleisin]]~~	+
-	~~[[Category: Muke]]~~	+
-	~~[[Category: Mukf]]~~	+
-	~~[[Category: Non-smc subunit~~]]	+

OCA at 09:16, 23 February 2022

OCA — Wed, 23 Feb 2022 09:16:38 GMT

←Older revision		Revision as of 09:16, 23 February 2022
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	<StructureSection load='3euh' size='340' side='right'caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3euh' size='340' side='right'caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EUH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EUH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3euj\|3euj]], [[3euk\|3euk]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [~~http~~://pdbe.org/3euh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3euh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3euh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [https://pdbe.org/3euh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [https://www.ebi.ac.uk/pdbsum/3euh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3euh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> [[~~http~~://www.uniprot.org/uniprot/Q6ITT5_ECOLX Q6ITT5_ECOLX]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.[HAMAP-Rule:MF_01802]	+	[[https://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> [[https://www.uniprot.org/uniprot/Q6ITT5_ECOLX Q6ITT5_ECOLX]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.[HAMAP-Rule:MF_01802]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:36, 7 August 2019

OCA — Wed, 07 Aug 2019 06:36:50 GMT

←Older revision		Revision as of 06:36, 7 August 2019
Line 1:		Line 1:

	==Crystal Structure of the MukE-MukF Complex==		==Crystal Structure of the MukE-MukF Complex==
-	<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='3euh' size='340' side='right'caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EUH FirstGlance]. <br>		<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EUH FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/3euh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/3euh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Ha, N C]]		[[Category: Ha, N C]]
	[[Category: Ku, B]]		[[Category: Ku, B]]

OCA at 09:20, 25 October 2017

OCA — Wed, 25 Oct 2017 09:20:06 GMT

←Older revision		Revision as of 09:20, 25 October 2017
Line 1:		Line 1:
		+
	==Crystal Structure of the MukE-MukF Complex==		==Crystal Structure of the MukE-MukF Complex==
	<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://pdbe.org/3euh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://pdbe.org/3euh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3euh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	[[Category: Suh, M K]]		[[Category: Suh, M K]]
	[[Category: Woo, J S]]		[[Category: Woo, J S]]
		+	[[Category: Calcium]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Cell division]]		[[Category: Cell division]]
Line 44:		Line 46:
	[[Category: Chromosome partition]]		[[Category: Chromosome partition]]
	[[Category: Condensin]]		[[Category: Condensin]]
		+	[[Category: Cytoplasm]]
	[[Category: Dna condensation]]		[[Category: Dna condensation]]
	[[Category: Kleisin]]		[[Category: Kleisin]]

OCA at 16:10, 7 February 2016

OCA — Sun, 07 Feb 2016 16:10:52 GMT

←Older revision		Revision as of 16:10, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EUH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EUH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://pdbe.org/3euh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3euh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3euh" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
		+	[[Category: Ecoli]]
	[[Category: Ha, N C]]		[[Category: Ha, N C]]
	[[Category: Ku, B]]		[[Category: Ku, B]]

OCA at 16:34, 24 December 2014

OCA — Wed, 24 Dec 2014 16:34:18 GMT

←Older revision		Revision as of 16:34, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> [[http://www.uniprot.org/uniprot/Q6ITT5_ECOLX Q6ITT5_ECOLX]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.[HAMAP-Rule:MF_01802]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:37, 26 November 2014

OCA — Wed, 26 Nov 2014 08:37:28 GMT

←Older revision		Revision as of 08:37, 26 November 2014
Line 1:		Line 1:
-	[[~~Image:~~3euh.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the MukE-MukF Complex==
		+	<StructureSection load='3euh' size='340' side='right' caption='[[3euh]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EUH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3euj\|3euj]], [[3euk\|3euk]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3euh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3euh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3euh RCSB], [http://www.ebi.ac.uk/pdbsum/3euh PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/3euh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Condensins are key mediators of chromosome condensation across organisms. Like other condensins, the bacterial MukBEF condensin complex consists of an SMC family protein dimer containing two ATPase head domains, MukB, and two interacting subunits, MukE and MukF. We report complete structural views of the intersubunit interactions of this condensin along with ensuing studies that reveal a role for the ATPase activity of MukB. MukE and MukF together form an elongated dimeric frame, and MukF's C-terminal winged-helix domains (C-WHDs) bind MukB heads to constitute closed ring-like structures. Surprisingly, one of the two bound C-WHDs is forced to detach upon ATP-mediated engagement of MukB heads. This detachment reaction depends on the linker segment preceding the C-WHD, and mutations on the linker restrict cell growth. Thus ATP-dependent transient disruption of the MukB-MukF interaction, which creates openings in condensin ring structures, is likely to be a critical feature of the functional mechanism of condensins.

-	~~{{STRUCTURE_3euh\| PDB=3euh \| SCENE= }}~~	+	Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.,Woo JS, Lim JH, Shin HC, Suh MK, Ku B, Lee KH, Joo K, Robinson H, Lee J, Park SY, Ha NC, Oh BH Cell. 2009 Jan 9;136(1):85-96. PMID:19135891<ref>PMID:19135891</ref>

-	~~===Crystal Structure~~ of the ~~MukE-MukF Complex===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19135891}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3euh]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019135891<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Ha, N C.]]	+	[[Category: Ha, N C]]
-	[[Category: Ku, B.]]	+	[[Category: Ku, B]]
-	[[Category: Oh, B H.]]	+	[[Category: Oh, B H]]
-	[[Category: Suh, M K.]]	+	[[Category: Suh, M K]]
-	[[Category: Woo, J S.]]	+	[[Category: Woo, J S]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Cell division]]		[[Category: Cell division]]

OCA: Protected "3euh" [edit=sysop:move=sysop]

OCA — Wed, 06 Feb 2013 13:20:35 GMT

Protected "3euh" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:20, 6 February 2013

OCA at 13:20, 6 February 2013

OCA — Wed, 06 Feb 2013 13:20:30 GMT

←Older revision		Revision as of 13:20, 6 February 2013
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-	{{Seed}}
	[[Image:3euh.png\|left\|200px]]		[[Image:3euh.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3euh\| PDB=3euh \| SCENE= }}		{{STRUCTURE_3euh\| PDB=3euh \| SCENE= }}

	===Crystal Structure of the MukE-MukF Complex===		===Crystal Structure of the MukE-MukF Complex===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19135891}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19135891 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19135891}}		{{ABSTRACT_PUBMED_19135891}}

	==About this Structure==		==About this Structure==
-	~~3EUH~~ is a 6 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA].	+	[[3euh]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19135891~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019135891</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ha, N C.]]		[[Category: Ha, N C.]]
Line 30:		Line 18:
	[[Category: Suh, M K.]]		[[Category: Suh, M K.]]
	[[Category: Woo, J S.]]		[[Category: Woo, J S.]]
-	[[Category: Calcium]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Cell division]]		[[Category: Cell division]]
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	[[Category: Chromosome partition]]		[[Category: Chromosome partition]]
	[[Category: Condensin]]		[[Category: Condensin]]
-	[[Category: Cytoplasm]]
	[[Category: Dna condensation]]		[[Category: Dna condensation]]
	[[Category: Kleisin]]		[[Category: Kleisin]]
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	[[Category: Mukf]]		[[Category: Mukf]]
	[[Category: Non-smc subunit]]		[[Category: Non-smc subunit]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 09:04:27 2010''

OCA at 07:04, 6 January 2010

OCA — Wed, 06 Jan 2010 07:04:28 GMT

←Older revision		Revision as of 07:04, 6 January 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3euh.~~jpg~~\|left\|200px]]	+	[[Image:3euh.png\|left\|200px]]

	<!--		<!--
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	===Crystal Structure of the MukE-MukF Complex===		===Crystal Structure of the MukE-MukF Complex===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19135891}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19135891 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19135891}}

	==About this Structure==		==About this Structure==
	3EUH is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA].		3EUH is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EUH OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19135891</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ha, N C.]]		[[Category: Ha, N C.]]
Line 34:		Line 43:
	[[Category: Non-smc subunit]]		[[Category: Non-smc subunit]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan ~~21 10~~:47:~~23 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 09:04:27 2010''