3ewa - Revision history

OCA at 06:36, 6 September 2023

OCA — Wed, 06 Sep 2023 06:36:47 GMT

←Older revision		Revision as of 06:36, 6 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [https://pdbe.org/3ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [https://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [https://pdbe.org/3ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [https://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:34, 30 September 2022

OCA — Fri, 30 Sep 2022 04:34:52 GMT

←Older revision		Revision as of 04:34, 30 September 2022
Line 3:		Line 3:
	<StructureSection load='3ewa' size='340' side='right'caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ewa' size='340' side='right'caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35294_[[methanococcus_deltae_corder_et_al._1988]] Atcc 35294 [[methanococcus deltae corder et al. 1988]]~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2etl\|2etl]], [[3ew9\|3ew9]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC 35294 [[Methanococcus deltae Corder et al. 1988]]])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [https://pdbe.org/3ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [https://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [https://pdbe.org/3ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [https://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~RADA_METMP RADA_METMP]~~] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/RADA_METMI RADA_METMI] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.[HAMAP-Rule:MF_00348]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~He, Y~~]]	+	[[Category: Methanococcus maripaludis]]
-	[[Category: ~~Li,~~ Y]]	+	[[Category: He Y]]
-	[[Category: ~~Luo,~~ Y]]	+	[[Category: Li Y]]
-	[[Category: ~~Atp analogue]]~~	+	[[Category: Luo Y]]
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Dna damage]]~~	+
-	~~[[Category: Dna recombination]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Rada]]~~	+
-	~~[[Category: Recombinase]]~~	+
-	~~[[Category: Recombination]]~~	+
-	~~[[Category: Strand exchange protein~~]]	+

OCA at 19:46, 20 October 2021

OCA — Wed, 20 Oct 2021 19:46:50 GMT

←Older revision		Revision as of 19:46, 20 October 2021
Line 1:		Line 1:

	==RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions==		==RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions==
-	<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3ewa' size='340' side='right'caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43000~~ Atcc ~~43000~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35294_[[methanococcus_deltae_corder_et_al._1988]] Atcc 35294 [[methanococcus deltae corder et al. 1988]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2etl\|2etl]], [[3ew9\|3ew9]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC ~~43000~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC 35294 [[Methanococcus deltae Corder et al. 1988]]])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [~~http~~://pdbe.org/3ewa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [https://pdbe.org/3ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [https://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RADA_METMP RADA_METMP]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).	+	[[https://www.uniprot.org/uniprot/RADA_METMP RADA_METMP]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Resolvase\|Resolvase]]	+	*[[Resolvase 3D structures\|Resolvase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 43000~~]]	+	[[Category: Large Structures]]
	[[Category: He, Y]]		[[Category: He, Y]]
	[[Category: Li, Y]]		[[Category: Li, Y]]

OCA at 21:59, 2 December 2018

OCA — Sun, 02 Dec 2018 21:59:07 GMT

←Older revision		Revision as of 21:59, 2 December 2018
Line 1:		Line 1:
		+
	==RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions==		==RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions==
	<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC 43000])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC 43000])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://pdbe.org/3ewa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://pdbe.org/3ewa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:52, 10 February 2016

OCA — Wed, 10 Feb 2016 01:52:31 GMT

←Older revision		Revision as of 01:52, 10 February 2016
Line 2:		Line 2:
	<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanococcus_maripaludis Methanococcus maripaludis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43000 Atcc 43000]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ~~Methanococcus maripaludis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 ATCC 43000])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://pdbe.org/3ewa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ewa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ewa" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanococcus maripaludis~~]]	+	[[Category: Atcc 43000]]
	[[Category: He, Y]]		[[Category: He, Y]]
	[[Category: Li, Y]]		[[Category: Li, Y]]

OCA at 10:58, 25 December 2014

OCA — Thu, 25 Dec 2014 10:58:39 GMT

←Older revision		Revision as of 10:58, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 Methanococcus maripaludis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 Methanococcus maripaludis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RADA_METMP RADA_METMP]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Methanococcus maripaludis]]		[[Category: Methanococcus maripaludis]]
-	[[Category: He, Y.]]	+	[[Category: He, Y]]
-	[[Category: Li, Y.]]	+	[[Category: Li, Y]]
-	[[Category: Luo, Y.]]	+	[[Category: Luo, Y]]
	[[Category: Atp analogue]]		[[Category: Atp analogue]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]

OCA at 13:22, 29 September 2014

OCA — Mon, 29 Sep 2014 13:22:09 GMT

←Older revision		Revision as of 13:22, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3ewa.~~png~~\|~~left~~\|200px]]	+	==RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions==
		+	<StructureSection load='3ewa' size='340' side='right' caption='[[3ewa]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2etl\|2etl]], [[3ew9\|3ew9]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MMP1222, radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39152 Methanococcus maripaludis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ewa RCSB], [http://www.ebi.ac.uk/pdbsum/3ewa PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Archaeal RadAs are close homologues of eukaryal Rad51s ( approximately 40% sequence identity). These recombinases promote ATP hydrolysis and a hallmark strand-exchange reaction between homologous single-stranded and double-stranded DNA substrates. Pairing of the 3'-overhangs located at the damaged DNA with a homologous double-stranded DNA enables the re-synthesis of the damaged region using the homologous DNA as the template. In recent studies, conformational changes in the DNA-interacting regions of Methanococcus voltae RadA have been correlated with the presence of activity-stimulating potassium or calcium ions in the ATPase centre. The series of crystal structures of M. maripaludis RadA presented here further suggest the conservation of an allosteric switch in the ATPase centre which controls the conformational status of DNA-interacting loops. Structural comparison with the distant Escherichia coli RecA homologue supports the notion that the conserved Lys248 and Lys250 residues in RecA play a role similar to that of cations in RadA. The conservation of a cationic bridge between the DNA-interacting L2 region and the terminal phosphate of ATP, together with the apparent stability of the nucleoprotein filament, suggests a gap-displacement model which may explain the advantage of ATP hydrolysis for DNA-strand exchange.

-	~~{{STRUCTURE_3ewa\| PDB=3ewa \| SCENE= }}~~	+	Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis.,Li Y, He Y, Luo Y Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):602-10. Epub 2009, May 15. PMID:19465774<ref>PMID:19465774</ref>

-	~~===RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19465774}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3ewa]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA].~~	+

	==See Also==		==See Also==
	*[[Resolvase\|Resolvase]]		*[[Resolvase\|Resolvase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019465774<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Methanococcus maripaludis]]		[[Category: Methanococcus maripaludis]]
	[[Category: He, Y.]]		[[Category: He, Y.]]

OCA at 15:54, 20 October 2012

OCA — Sat, 20 Oct 2012 15:54:19 GMT

←Older revision		Revision as of 15:54, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3ewa]] is a 1 chain structure ~~of [[Resolvase]]~~ with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA].	+	[[3ewa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA].

	==See Also==		==See Also==

OCA: Protected "3ewa" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 19:52:03 GMT

Protected "3ewa" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:52, 26 July 2012

OCA at 19:52, 26 July 2012

OCA — Thu, 26 Jul 2012 19:52:01 GMT

←Older revision		Revision as of 19:52, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3ewa.png\|left\|200px]]		[[Image:3ewa.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ewa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ewa\| PDB=3ewa \| SCENE= }}		{{STRUCTURE_3ewa\| PDB=3ewa \| SCENE= }}

	===RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions===		===RADA recombinase from METHANOCOCCUS MARIPALUDIS in complex with AMPPNP and ammonium ions===

		+	{{ABSTRACT_PUBMED_19465774}}

	==About this Structure==		==About this Structure==
-	~~3EWA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA].	+	[[3ewa]] is a 1 chain structure of [[Resolvase]] with sequence from [http://en.wikipedia.org/wiki/Methanococcus_maripaludis Methanococcus maripaludis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWA OCA].
		+
		+	==See Also==
		+	*[[Resolvase\|Resolvase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:019465774</ref><references group="xtra"/>
	[[Category: Methanococcus maripaludis]]		[[Category: Methanococcus maripaludis]]
	[[Category: He, Y.]]		[[Category: He, Y.]]
Line 31:		Line 31:
	[[Category: Recombination]]		[[Category: Recombination]]
	[[Category: Strand exchange protein]]		[[Category: Strand exchange protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 20:10:44 2009''