3ews - Revision history

OCA at 00:25, 28 December 2023

OCA — Thu, 28 Dec 2023 00:25:34 GMT

←Older revision		Revision as of 00:25, 28 December 2023
Line 3:		Line 3:
	<StructureSection load='3ews' size='340' side='right'caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3ews' size='340' side='right'caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWS FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADP:ADENOSINE~~-~~5-DIPHOSPHATE'>ADP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~DBP5, DDX19, DDX19B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=5~~&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [https://pdbe.org/3ews PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [https://www.ebi.ac.uk/pdbsum/3ews PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ews ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [https://pdbe.org/3ews PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [https://www.ebi.ac.uk/pdbsum/3ews PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ews ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN]] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.	+	[https://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Andersson, j]]	+	[[Category: Andersson j]]
-	[[Category: Arrowsmith~~, c h~~]]	+	[[Category: Arrowsmith ch]]
-	[[Category: Berglund, h]]	+	[[Category: Berglund h]]
-	[[Category: Bountra, c]]	+	[[Category: Bountra c]]
-	[[Category: Collins, r]]	+	[[Category: Collins r]]
-	[[Category: Dahlgren~~, l g~~]]	+	[[Category: Dahlgren lg]]
-	[[Category: Edwards~~, a m~~]]	+	[[Category: Edwards am]]
-	[[Category: Flodin, s]]	+	[[Category: Flodin s]]
-	[[Category: Flores, a]]	+	[[Category: Flores a]]
-	[[Category: Graslund, s]]	+	[[Category: Graslund s]]
-	[[Category: Hammarstrom, m]]	+	[[Category: Hammarstrom m]]
-	[[Category: Johansson, a]]	+	[[Category: Johansson a]]
-	[[Category: Johansson, i]]	+	[[Category: Johansson i]]
-	[[Category: Karlberg, t]]	+	[[Category: Karlberg t]]
-	[[Category: Kotenyova, t]]	+	[[Category: Kotenyova t]]
-	[[Category: Lehtio, l]]	+	[[Category: Lehtio l]]
-	[[Category: Moche, m]]	+	[[Category: Moche m]]
-	[[Category: Nilsson~~, m e~~]]	+	[[Category: Nilsson me]]
-	[[Category: Nordlund, p]]	+	[[Category: Nordlund p]]
-	[[Category: Nyman, t]]	+	[[Category: Nyman t]]
-	[[Category: Olesen, k]]	+	[[Category: Olesen k]]
-	[[Category: Persson, c]]	+	[[Category: Persson c]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Sagemark j]]
-	[[Category: Sagemark, j]]	+	[[Category: Schueler h]]
-	[[Category: Schueler, h]]	+	[[Category: Thorsell ag]]
-	[[Category: Thorsell~~, a g~~]]	+	[[Category: Tresaugues l]]
-	[[Category: Tresaugues, l]]	+	[[Category: Van den berg s]]
-	[[Category: ~~Weigelt, j~~]]	+	[[Category: Weigelt j]]
-	[[Category: ~~Welin, m~~]]	+	[[Category: Welin m]]
-	[[Category: ~~Wikstrom,~~ m]]	+	[[Category: Wikstrom m]]
-	[[Category: ~~Wisniewska,~~ m]]	+	[[Category: Wisniewska m]]
-	[[Category: ~~Berg, s Van den]]~~	+
-	~~[[Category: Adp]]~~	+
-	~~[[Category: Alternative splicing]]~~	+
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Dead]]~~	+
-	~~[[Category: Helicase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Membrane]]~~	+
-	~~[[Category: Mrna]]~~	+
-	~~[[Category: Mrna transport]]~~	+
-	~~[[Category: Nuclear pore complex]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Rna helicase]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rrna]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Translocation]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 09:18, 23 February 2022

OCA — Wed, 23 Feb 2022 09:18:18 GMT

←Older revision		Revision as of 09:18, 23 February 2022
Line 1:		Line 1:

	==Human DEAD-box RNA-helicase DDX19 in complex with ADP==		==Human DEAD-box RNA-helicase DDX19 in complex with ADP==
-	<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='3ews' size='340' side='right'caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [~~http~~://pdbe.org/3ews PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ews PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ews ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [https://pdbe.org/3ews PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [https://www.ebi.ac.uk/pdbsum/3ews PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ews ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN]] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.	+	[[https://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN]] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[DEAD-box RNA-helicase DDX19 in complex with ADP\|DEAD-box RNA-helicase DDX19 in complex with ADP]]	+	*[[Helicase 3D structures\|Helicase 3D structures]]
-	*[[Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA\|Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA]]	+
-	*[[Helicase\|Helicase]]	+
	== References ==		== References ==
	<references/>		<references/>
Line 39:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Andersson, j]]		[[Category: Andersson, j]]
	[[Category: Arrowsmith, c h]]		[[Category: Arrowsmith, c h]]

OCA at 21:27, 2 December 2018

OCA — Sun, 02 Dec 2018 21:27:06 GMT

←Older revision		Revision as of 21:27, 2 December 2018
Line 1:		Line 1:
		+
	==Human DEAD-box RNA-helicase DDX19 in complex with ADP==		==Human DEAD-box RNA-helicase DDX19 in complex with ADP==
	<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://pdbe.org/3ews PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://pdbe.org/3ews PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ews ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ews_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ews_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 38:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
-	[[Category: Andersson,j]]	+	[[Category: Andersson, j]]
-	[[Category: Arrowsmith,c h]]	+	[[Category: Arrowsmith, c h]]
-	[[Category: Berglund,h]]	+	[[Category: Berglund, h]]
	[[Category: Bountra, c]]		[[Category: Bountra, c]]
-	[[Category: Collins,r]]	+	[[Category: Collins, r]]
-	[[Category: Dahlgren,l g]]	+	[[Category: Dahlgren, l g]]
-	[[Category: Edwards,a m]]	+	[[Category: Edwards, a m]]
-	[[Category: Flodin,s]]	+	[[Category: Flodin, s]]
-	[[Category: Flores,a]]	+	[[Category: Flores, a]]
-	[[Category: Graslund,s]]	+	[[Category: Graslund, s]]
-	[[Category: Hammarstrom,m]]	+	[[Category: Hammarstrom, m]]
-	[[Category: Johansson,a]]	+	[[Category: Johansson, a]]
-	[[Category: Johansson,i]]	+	[[Category: Johansson, i]]
-	[[Category: Karlberg,t]]	+	[[Category: Karlberg, t]]
-	[[Category: Kotenyova,t]]	+	[[Category: Kotenyova, t]]
-	[[Category: Lehtio,l]]	+	[[Category: Lehtio, l]]
-	[[Category: Moche,m]]	+	[[Category: Moche, m]]
-	[[Category: Nilsson,m e]]	+	[[Category: Nilsson, m e]]
-	[[Category: Nordlund,p]]	+	[[Category: Nordlund, p]]
-	[[Category: Nyman,t]]	+	[[Category: Nyman, t]]
-	[[Category: Olesen,k]]	+	[[Category: Olesen, k]]
-	[[Category: Persson,c]]	+	[[Category: Persson, c]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-	[[Category: Sagemark,j]]	+	[[Category: Sagemark, j]]
-	[[Category: Schueler,h]]	+	[[Category: Schueler, h]]
-	[[Category: Thorsell,a g]]	+	[[Category: Thorsell, a g]]
-	[[Category: Tresaugues,l]]	+	[[Category: Tresaugues, l]]
	[[Category: Weigelt, j]]		[[Category: Weigelt, j]]
-	[[Category: Welin,m]]	+	[[Category: Welin, m]]
-	[[Category: Wikstrom,m]]	+	[[Category: Wikstrom, m]]
-	[[Category: Wisniewska,m]]	+	[[Category: Wisniewska, m]]
	[[Category: Berg, s Van den]]		[[Category: Berg, s Van den]]
	[[Category: Adp]]		[[Category: Adp]]
		+	[[Category: Alternative splicing]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
		+	[[Category: Cytoplasm]]
	[[Category: Dead]]		[[Category: Dead]]
	[[Category: Helicase]]		[[Category: Helicase]]

OCA at 03:45, 8 February 2016

OCA — Mon, 08 Feb 2016 03:45:55 GMT

←Older revision		Revision as of 03:45, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://pdbe.org/3ews PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ews ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ews" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Andersson,j]]		[[Category: Andersson,j]]
	[[Category: Arrowsmith,c h]]		[[Category: Arrowsmith,c h]]

OCA at 20:21, 24 December 2014

OCA — Wed, 24 Dec 2014 20:21:06 GMT

←Older revision		Revision as of 20:21, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DD19B_HUMAN DD19B_HUMAN]] ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:51, 17 December 2014

OCA — Wed, 17 Dec 2014 13:51:37 GMT

←Older revision		Revision as of 13:51, 17 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3ews\| PDB=3ews \| SCENE= }}~~	+	==Human DEAD-box RNA-helicase DDX19 in complex with ADP==
-	===Human DEAD-box RNA-helicase DDX19 in complex with ADP===	+	<StructureSection load='3ews' size='340' side='right' caption='[[3ews]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19244245}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ews]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EWS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DBP5, DDX19, DDX19B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ews FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ews OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ews RCSB], [http://www.ebi.ac.uk/pdbsum/3ews PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ews_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DEXD/H-box RNA helicases couple ATP hydrolysis to RNA remodeling by an unknown mechanism. We used x-ray crystallography and biochemical analysis of the human DEXD/H-box protein DDX19 to investigate its regulatory mechanism. The crystal structures of DDX19, in its RNA-bound prehydrolysis and free posthydrolysis state, reveal an alpha-helix that inserts between the conserved domains of the free protein to negatively regulate ATPase activity. This finding was corroborated by biochemical data that confirm an autoregulatory function of the N-terminal region of the protein. This is the first study describing crystal structures of a DEXD/H-box protein in its open and closed cleft conformations.

-	~~==About this Structure==~~	+	The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch.,Collins R, Karlberg T, Lehtio L, Schutz P, van den Berg S, Dahlgren LG, Hammarstrom M, Weigelt J, Schuler H J Biol Chem. 2009 Apr 17;284(16):10296-300. Epub 2009 Feb 25. PMID:19244245<ref>PMID:19244245</ref>
-	~~[[3ews]] is a 2 chain structure with sequence from [http:/~~/en.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3EWS OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
Line 10:		Line 30:
	*[[Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA\|Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA]]		*[[Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA\|Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA]]
	*[[Helicase\|Helicase]]		*[[Helicase\|Helicase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019244245<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Andersson,j.]]	+	[[Category: Andersson,j]]
-	[[Category: Arrowsmith,c h.]]	+	[[Category: Arrowsmith,c h]]
-	[[Category: Berglund,h.]]	+	[[Category: Berglund,h]]
-	[[Category: Bountra, c.]]	+	[[Category: Bountra, c]]
-	[[Category: Collins,r.]]	+	[[Category: Collins,r]]
-	[[Category: Dahlgren,l g.]]	+	[[Category: Dahlgren,l g]]
-	[[Category: Edwards,a m.]]	+	[[Category: Edwards,a m]]
-	[[Category: Flodin,s.]]	+	[[Category: Flodin,s]]
-	[[Category: Flores,a.]]	+	[[Category: Flores,a]]
-	[[Category: Graslund,s.]]	+	[[Category: Graslund,s]]
-	[[Category: Hammarstrom,m.]]	+	[[Category: Hammarstrom,m]]
-	[[Category: Johansson,a.]]	+	[[Category: Johansson,a]]
-	[[Category: Johansson,i.]]	+	[[Category: Johansson,i]]
-	[[Category: Karlberg,t.]]	+	[[Category: Karlberg,t]]
-	[[Category: Kotenyova,t.]]	+	[[Category: Kotenyova,t]]
-	[[Category: Lehtio,l.]]	+	[[Category: Lehtio,l]]
-	[[Category: Moche,m.]]	+	[[Category: Moche,m]]
-	[[Category: Nilsson,m e.]]	+	[[Category: Nilsson,m e]]
-	[[Category: Nordlund,p.]]	+	[[Category: Nordlund,p]]
-	[[Category: Nyman,t.]]	+	[[Category: Nyman,t]]
-	[[Category: Olesen,k.]]	+	[[Category: Olesen,k]]
-	[[Category: Persson,c.]]	+	[[Category: Persson,c]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Sagemark,j.]]	+	[[Category: Sagemark,j]]
-	[[Category: Schueler,h.]]	+	[[Category: Schueler,h]]
-	[[Category: Thorsell,a g.]]	+	[[Category: Thorsell,a g]]
-	[[Category: Tresaugues,l.]]	+	[[Category: Tresaugues,l]]
-	[[Category: Weigelt, j.]]	+	[[Category: Weigelt, j]]
-	[[Category: Welin,m.]]	+	[[Category: Welin,m]]
-	[[Category: Wikstrom,m.]]	+	[[Category: Wikstrom,m]]
-	[[Category: Wisniewska,m.]]	+	[[Category: Wisniewska,m]]
-	[[Category: Berg, s Van den.]]	+	[[Category: Berg, s Van den]]
	[[Category: Adp]]		[[Category: Adp]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
Line 62:		Line 83:
	[[Category: Rrna]]		[[Category: Rrna]]
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomic]]
-	[[Category: Structural genomics consortium]]
	[[Category: Translocation]]		[[Category: Translocation]]
	[[Category: Transport]]		[[Category: Transport]]

OCA at 09:42, 11 March 2013

OCA — Mon, 11 Mar 2013 09:42:52 GMT

←Older revision		Revision as of 09:42, 11 March 2013
Line 1:		Line 1:
-	[[Image:3ews.png\|left\|200px]]
-
	{{STRUCTURE_3ews\| PDB=3ews \| SCENE= }}		{{STRUCTURE_3ews\| PDB=3ews \| SCENE= }}
-
	===Human DEAD-box RNA-helicase DDX19 in complex with ADP===		===Human DEAD-box RNA-helicase DDX19 in complex with ADP===
-
	{{ABSTRACT_PUBMED_19244245}}		{{ABSTRACT_PUBMED_19244245}}

OCA at 08:47, 20 October 2012

OCA — Sat, 20 Oct 2012 08:47:48 GMT

←Older revision		Revision as of 08:47, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3ews]] is a 2 chain structure ~~of [[Helicase]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA].	+	[[3ews]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWS OCA].

	==See Also==		==See Also==

OCA at 20:46, 25 July 2012

OCA — Wed, 25 Jul 2012 20:46:32 GMT

←Older revision		Revision as of 20:46, 25 July 2012
Line 1:		Line 1:
	[[Image:3ews.png\|left\|200px]]		[[Image:3ews.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ews", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ews\| PDB=3ews \| SCENE= }}		{{STRUCTURE_3ews\| PDB=3ews \| SCENE= }}

	===Human DEAD-box RNA-helicase DDX19 in complex with ADP===		===Human DEAD-box RNA-helicase DDX19 in complex with ADP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19244245}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19244245 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19244245}}		{{ABSTRACT_PUBMED_19244245}}

Line 25:		Line 14:
	*[[Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA\|Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA]]		*[[Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA\|Dead-box RNA helicase DDX19%2C in complex with an ATP-analogue and RNA]]
	*[[Helicase\|Helicase]]		*[[Helicase\|Helicase]]
-	*[[Morphs\|Morphs]]
-	*[[User:Wayne Decatur\|User:Wayne Decatur]]
-	*[[User:Wayne Decatur/3ewsSLASH3g0h Morph methods\|User:Wayne Decatur/3ewsSLASH3g0h Morph methods]]
-	*[[User:Wayne Decatur/3fpn Morph methods\|User:Wayne Decatur/3fpn Morph methods]]

	==Reference==		==Reference==

OCA: Protected "3ews" [edit=sysop:move=sysop]

OCA — Wed, 13 Jun 2012 10:42:24 GMT

Protected "3ews" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:42, 13 June 2012