3fo8 - Revision history

OCA at 09:50, 21 February 2024

OCA — Wed, 21 Feb 2024 09:50:04 GMT

←Older revision		Revision as of 09:50, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3fo8' size='340' side='right'caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fo8' size='340' side='right'caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">18, GB AAA32541.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [https://pdbe.org/3fo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fo8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [https://pdbe.org/3fo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fo8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~VG18_BPT4 VG18_BPT4~~]~~] The contractile tail~~ of bacteriophage T4 consists of a contractile sheath, a tube and a baseplate. ~~144 protomers~~ of ~~Gp18~~, ~~arranged in 24 annuli~~, ~~form~~ the contractile ~~tail~~ sheath ~~which participates in viral~~ DNA ~~injection~~ into host ~~cytoplasm~~.	+	[https://www.uniprot.org/uniprot/TSP_BPT4 TSP_BPT4] Structural component of the bacteriophage tail which consists of a contractile sheath, a tube and a baseplate. The central cylindrical segment of the tail consists of a rigid tube, composed of multiple copies of gp19, surrounded by the outer contractile sheath assembled from gp18 subunits. A total of 138 copies of gp18 arranged into 23 hexameric rings constitutes the sheath. During infection, contraction of the sheath drives the central tube through the host outer membrane, creating a channel for DNA ejection from the capsid into the host cell.<ref>PMID:14625682</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fo8 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fo8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The contractile tail of bacteriophage T4 is a molecular machine that facilitates very high viral infection efficiency. Its major component is a tail sheath, which contracts during infection to less than half of its initial length. The sheath consists of 138 copies of the tail sheath protein, gene product (gp) 18, which surrounds the central non-contractile tail tube. The contraction of the sheath drives the tail tube through the outer membrane, creating a channel for the viral genome delivery. A crystal structure of about three quarters of gp18 has been determined and was fitted into cryo-electron microscopy reconstructions of the tail sheath before and after contraction. It was shown that during contraction, gp18 subunits slide over each other with no apparent change in their structure.
-
-	The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.,Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296<ref>PMID:19229296</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3fo8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aksyuk~~, A A~~]]	+	[[Category: Aksyuk AA]]
-	[[Category: Kostyuchenko~~, V A~~]]	+	[[Category: Kostyuchenko VA]]
-	[[Category: Kurochkina~~, L P~~]]	+	[[Category: Kurochkina LP]]
-	[[Category: Leiman~~, P G~~]]	+	[[Category: Leiman PG]]
-	[[Category: Mesyanzhinov~~, V V~~]]	+	[[Category: Mesyanzhinov VV]]
-	[[Category: Rossmann~~, M G~~]]	+	[[Category: Rossmann MG]]
-	[[Category: Shneider~~, M M]]~~	+	[[Category: Shneider MM]]
-	~~[[Category: Bacteriophage t4]]~~	+
-	~~[[Category: Mostly beta]]~~	+
-	~~[[Category: Tail sheath]]~~	+
-	~~[[Category: Viral protein]]~~	+
-	~~[[Category: Viral structural protein~~]]	+

OCA at 08:06, 2 March 2022

OCA — Wed, 02 Mar 2022 08:06:21 GMT

←Older revision		Revision as of 08:06, 2 March 2022
Line 1:		Line 1:

	==Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR==		==Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR==
-	<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3fo8' size='340' side='right'caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [~~http~~://pdbe.org/3fo8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fo8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fo8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [https://pdbe.org/3fo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [https://www.ebi.ac.uk/pdbsum/3fo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fo8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/VG18_BPT4 VG18_BPT4]] The contractile tail of bacteriophage T4 consists of a contractile sheath, a tube and a baseplate. 144 protomers of Gp18, arranged in 24 annuli, form the contractile tail sheath which participates in viral DNA injection into host cytoplasm.	+	[[https://www.uniprot.org/uniprot/VG18_BPT4 VG18_BPT4]] The contractile tail of bacteriophage T4 consists of a contractile sheath, a tube and a baseplate. 144 protomers of Gp18, arranged in 24 annuli, form the contractile tail sheath which participates in viral DNA injection into host cytoplasm.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/3fo8_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/3fo8_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bpt4]]		[[Category: Bpt4]]
		+	[[Category: Large Structures]]
	[[Category: Aksyuk, A A]]		[[Category: Aksyuk, A A]]
	[[Category: Kostyuchenko, V A]]		[[Category: Kostyuchenko, V A]]

OCA at 06:46, 1 November 2017

OCA — Wed, 01 Nov 2017 06:46:20 GMT

←Older revision		Revision as of 06:46, 1 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR==		==Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR==
	<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://pdbe.org/3fo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://pdbe.org/3fo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fo8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:14, 8 February 2016

OCA — Mon, 08 Feb 2016 06:14:42 GMT

←Older revision		Revision as of 06:14, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 ~~Enterobacteria phage T4~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://pdbe.org/3fo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fo8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3fo8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Aksyuk, A A]]		[[Category: Aksyuk, A A]]
	[[Category: Kostyuchenko, V A]]		[[Category: Kostyuchenko, V A]]

OCA at 21:13, 24 December 2014

OCA — Wed, 24 Dec 2014 21:13:58 GMT

←Older revision		Revision as of 21:13, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VG18_BPT4 VG18_BPT4]] The contractile tail of bacteriophage T4 consists of a contractile sheath, a tube and a baseplate. 144 protomers of Gp18, arranged in 24 annuli, form the contractile tail sheath which participates in viral DNA injection into host cytoplasm.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.,Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296<ref>PMID:19229296</ref>		The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.,Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296<ref>PMID:19229296</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
-	[[Category: Aksyuk, A A.]]	+	[[Category: Aksyuk, A A]]
-	[[Category: Kostyuchenko, V A.]]	+	[[Category: Kostyuchenko, V A]]
-	[[Category: Kurochkina, L P.]]	+	[[Category: Kurochkina, L P]]
-	[[Category: Leiman, P G.]]	+	[[Category: Leiman, P G]]
-	[[Category: Mesyanzhinov, V V.]]	+	[[Category: Mesyanzhinov, V V]]
-	[[Category: Rossmann, M G.]]	+	[[Category: Rossmann, M G]]
-	[[Category: Shneider, M M.]]	+	[[Category: Shneider, M M]]
	[[Category: Bacteriophage t4]]		[[Category: Bacteriophage t4]]
	[[Category: Mostly beta]]		[[Category: Mostly beta]]

OCA: Protected "3fo8" [edit=sysop:move=sysop]

OCA — Wed, 21 May 2014 09:39:49 GMT

Protected "3fo8" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:39, 21 May 2014

OCA at 09:39, 21 May 2014

OCA — Wed, 21 May 2014 09:39:47 GMT

←Older revision		Revision as of 09:39, 21 May 2014
Line 1:		Line 1:
-	~~{{Seed}}~~	+	==Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR==
-	[[~~Image:~~3fo8.~~png~~\|~~left~~\|200px]]	+	<StructureSection load='3fo8' size='340' side='right' caption='[[3fo8]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3fo8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FO8 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3foa\|3foa]], [[3foh\|3foh]], [[3foi\|3foi]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">18, GB AAA32541.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fo8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fo8 RCSB], [http://www.ebi.ac.uk/pdbsum/3fo8 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/3fo8_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The contractile tail of bacteriophage T4 is a molecular machine that facilitates very high viral infection efficiency. Its major component is a tail sheath, which contracts during infection to less than half of its initial length. The sheath consists of 138 copies of the tail sheath protein, gene product (gp) 18, which surrounds the central non-contractile tail tube. The contraction of the sheath drives the tail tube through the outer membrane, creating a channel for the viral genome delivery. A crystal structure of about three quarters of gp18 has been determined and was fitted into cryo-electron microscopy reconstructions of the tail sheath before and after contraction. It was shown that during contraction, gp18 subunits slide over each other with no apparent change in their structure.

-	~~<!--~~	+	The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.,Aksyuk AA, Leiman PG, Kurochkina LP, Shneider MM, Kostyuchenko VA, Mesyanzhinov VV, Rossmann MG EMBO J. 2009 Apr 8;28(7):821-9. Epub 2009 Feb 19. PMID:19229296<ref>PMID:19229296</ref>
-	The ~~line below this paragraph~~, ~~containing "STRUCTURE_3fo8"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3fo8\| PDB=3fo8 \| SCENE= }}~~	+

-	~~===Crystal structure~~ of the ~~bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_19229296}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 19229296 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_19229296}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~3FO8 is a 1 chain structure of sequence from [http:~~/~~/en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:19229296<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Aksyuk, A A.]]		[[Category: Aksyuk, A A.]]
Line 37:		Line 43:
	[[Category: Viral protein]]		[[Category: Viral protein]]
	[[Category: Viral structural protein]]		[[Category: Viral structural protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 10:42:04 2009''

OCA at 07:42, 22 April 2009

OCA — Wed, 22 Apr 2009 07:42:05 GMT

←Older revision		Revision as of 07:42, 22 April 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3fo8.~~jpg~~\|left\|200px]]	+	[[Image:3fo8.png\|left\|200px]]

	<!--		<!--
Line 38:		Line 38:
	[[Category: Viral structural protein]]		[[Category: Viral structural protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 11 11~~:17:15 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 10:42:04 2009''

OCA at 09:17, 11 March 2009

OCA — Wed, 11 Mar 2009 09:17:16 GMT

←Older revision		Revision as of 09:17, 11 March 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fo8.jpg\|left\|200px]]

-	The ~~entry 3fo8~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fo8", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fo8\| PDB=3fo8 \| SCENE= }}

-	~~Authors: Aksyuk~~, ~~A.A., Leiman, P.G., Kurochkina, L.P., Shneider, M.M., Kostyuchenko, V.A., Mesyanzhinov, V.V., Rossmann, M.G.~~	+	===Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR===

-	Description: Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 14 12~~:55:12 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19229296}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19229296 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19229296}}
		+
		+	==About this Structure==
		+	3FO8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FO8 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19229296</ref><references group="xtra"/>
		+	[[Category: Enterobacteria phage t4]]
		+	[[Category: Aksyuk, A A.]]
		+	[[Category: Kostyuchenko, V A.]]
		+	[[Category: Kurochkina, L P.]]
		+	[[Category: Leiman, P G.]]
		+	[[Category: Mesyanzhinov, V V.]]
		+	[[Category: Rossmann, M G.]]
		+	[[Category: Shneider, M M.]]
		+	[[Category: Bacteriophage t4]]
		+	[[Category: Mostly beta]]
		+	[[Category: Tail sheath]]
		+	[[Category: Viral protein]]
		+	[[Category: Viral structural protein]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 11:17:15 2009''

OCA: New page: '''Unreleased structure''' The entry 3fo8 is ON HOLD until Paper Publication Authors: Aksyuk, A.A., Leiman, P.G., Kurochkina, L.P., Shneider, M.M., Kostyuchenko, V.A., Mesyanzhinov, V.V...

OCA — Wed, 14 Jan 2009 10:55:13 GMT

New page: '''Unreleased structure''' The entry 3fo8 is ON HOLD until Paper Publication Authors: Aksyuk, A.A., Leiman, P.G., Kurochkina, L.P., Shneider, M.M., Kostyuchenko, V.A., Mesyanzhinov, V.V...

New page

'''Unreleased structure'''

The entry 3fo8 is ON HOLD until Paper Publication

Authors: Aksyuk, A.A., Leiman, P.G., Kurochkina, L.P., Shneider, M.M., Kostyuchenko, V.A., Mesyanzhinov, V.V., Rossmann, M.G.

Description: Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 12:55:12 2009''