3fri - Revision history

OCA at 15:31, 1 November 2023

OCA — Wed, 01 Nov 2023 15:31:56 GMT

←Older revision		Revision as of 15:31, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3fri' size='340' side='right'caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fri' size='340' side='right'caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FRI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FRI FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SAH:S~~-~~ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3frh\|3frh]], [[3fzg\|3fzg]]~~</~~div~~>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [https://pdbe.org/3fri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [https://www.ebi.ac.uk/pdbsum/3fri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fri ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [https://pdbe.org/3fri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [https://www.ebi.ac.uk/pdbsum/3fri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fri ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q763K9_ECOLX Q763K9_ECOLX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Courvalin, P]]	+	[[Category: Courvalin P]]
-	[[Category: Dupechez, M]]	+	[[Category: Dupechez M]]
-	[[Category: Galimand, M]]	+	[[Category: Galimand M]]
-	[[Category: Mechulam, Y]]	+	[[Category: Mechulam Y]]
-	[[Category: Panvert, M]]	+	[[Category: Panvert M]]
-	[[Category: Schmitt, E]]	+	[[Category: Schmitt E]]
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Methyltransferase domain]]~~	+
-	~~[[Category: N-terminal helical domain]]~~	+
-	~~[[Category: Plasmid]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:08, 2 March 2022

OCA — Wed, 02 Mar 2022 08:08:50 GMT

←Older revision		Revision as of 08:08, 2 March 2022
Line 1:		Line 1:

	==Structure of the 16S rRNA methylase RmtB, I222==		==Structure of the 16S rRNA methylase RmtB, I222==
-	<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3fri' size='340' side='right'caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FRI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FRI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3frh\|3frh]], [[3fzg\|3fzg]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [~~http~~://pdbe.org/3fri PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fri PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fri ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [https://pdbe.org/3fri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [https://www.ebi.ac.uk/pdbsum/3fri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fri ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Courvalin, P]]		[[Category: Courvalin, P]]
	[[Category: Dupechez, M]]		[[Category: Dupechez, M]]

OCA at 07:20, 5 December 2018

OCA — Wed, 05 Dec 2018 07:20:11 GMT

←Older revision		Revision as of 07:20, 5 December 2018
Line 1:		Line 1:
		+
	==Structure of the 16S rRNA methylase RmtB, I222==		==Structure of the 16S rRNA methylase RmtB, I222==
	<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [http://pdbe.org/3fri PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [http://www.ebi.ac.uk/pdbsum/3fri PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [http://pdbe.org/3fri PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [http://www.ebi.ac.uk/pdbsum/3fri PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fri ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/3fri_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/3fri_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 41:		Line 42:
	[[Category: Methyltransferase domain]]		[[Category: Methyltransferase domain]]
	[[Category: N-terminal helical domain]]		[[Category: N-terminal helical domain]]
		+	[[Category: Plasmid]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 00:56, 10 February 2016

OCA — Wed, 10 Feb 2016 00:56:07 GMT

←Older revision		Revision as of 00:56, 10 February 2016
Line 2:		Line 2:
	<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FRI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FRI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [http://www.ebi.ac.uk/pdbsum/3fri PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [http://pdbe.org/3fri PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [http://www.ebi.ac.uk/pdbsum/3fri PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fri ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3fri" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Courvalin, P]]		[[Category: Courvalin, P]]
	[[Category: Dupechez, M]]		[[Category: Dupechez, M]]

OCA at 10:09, 3 December 2014

OCA — Wed, 03 Dec 2014 10:09:10 GMT

←Older revision		Revision as of 10:09, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3fri.~~png~~\|~~left~~\|200px]]	+	==Structure of the 16S rRNA methylase RmtB, I222==
		+	<StructureSection load='3fri' size='340' side='right' caption='[[3fri]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3fri]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FRI FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3frh\|3frh]], [[3fzg\|3fzg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RmtB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fri OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fri RCSB], [http://www.ebi.ac.uk/pdbsum/3fri PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fr/3fri_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aminoglycosides are used extensively for the treatment of severe infections due to Gram-negative bacteria. However, certain species have become highly resistant after acquisition of genes for methyltransferases which catalyze post-transcriptional methylation of N7-G1405 in 16 S rRNA of 30 S ribosomal subunits. Inactivation of this enzymatic activity is therefore an important challenge for development of an effective therapy. The present work describes the crystallographic structures of methyltransferases RmtB and ArmA from clinical isolates. Together with biochemical experiments, the 3D structures indicate that the N-terminal domain specific for this family of methyltransferases is required for enzymatic activity. Site-directed mutagenesis has enabled important residues for catalysis and RNA binding to be identified. These high-resolution structures should underpin the design of potential inhibitors of these enzymes, which could be used to restore the activity of aminoglycosides against resistant pathogens.

-	~~{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}~~	+	Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases.,Schmitt E, Galimand M, Panvert M, Courvalin P, Mechulam Y J Mol Biol. 2009 May 8;388(3):570-82. Epub 2009 Mar 20. PMID:19303884<ref>PMID:19303884</ref>

-	~~===Structure~~ of the ~~16S rRNA methylase RmtB, I222===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19303884}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3fri]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019303884<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Courvalin, P.]]	+	[[Category: Courvalin, P]]
-	[[Category: Dupechez, M.]]	+	[[Category: Dupechez, M]]
-	[[Category: Galimand, M.]]	+	[[Category: Galimand, M]]
-	[[Category: Mechulam, Y.]]	+	[[Category: Mechulam, Y]]
-	[[Category: Panvert, M.]]	+	[[Category: Panvert, M]]
-	[[Category: Schmitt, E.]]	+	[[Category: Schmitt, E]]
	[[Category: Methyltransferase]]		[[Category: Methyltransferase]]
	[[Category: Methyltransferase domain]]		[[Category: Methyltransferase domain]]
	[[Category: N-terminal helical domain]]		[[Category: N-terminal helical domain]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA: Protected "3fri" [edit=sysop:move=sysop]

OCA — Wed, 20 Feb 2013 14:23:52 GMT

Protected "3fri" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:23, 20 February 2013

OCA at 14:23, 20 February 2013

OCA — Wed, 20 Feb 2013 14:23:48 GMT

←Older revision		Revision as of 14:23, 20 February 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3fri.png\|left\|200px]]		[[Image:3fri.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3fri", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}		{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}

	===Structure of the 16S rRNA methylase RmtB, I222===		===Structure of the 16S rRNA methylase RmtB, I222===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19303884}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19303884 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19303884}}		{{ABSTRACT_PUBMED_19303884}}

	==About this Structure==		==About this Structure==
-	~~3FRI~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].	+	[[3fri]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19303884~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019303884</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Courvalin, P.]]		[[Category: Courvalin, P.]]
Line 34:		Line 22:
	[[Category: Methyltransferase domain]]		[[Category: Methyltransferase domain]]
	[[Category: N-terminal helical domain]]		[[Category: N-terminal helical domain]]
-	[[Category: Plasmid]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 13:57:21 2010''

OCA at 11:57, 3 March 2010

OCA — Wed, 03 Mar 2010 11:57:22 GMT

←Older revision		Revision as of 11:57, 3 March 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3fri.~~jpg~~\|left\|200px]]	+	[[Image:3fri.png\|left\|200px]]

	<!--		<!--
Line 10:		Line 10:
	{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}		{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}

-	===Structure of ~~an escherichia coli methyltransferase~~, ~~I 2 2 2~~===	+	===Structure of the 16S rRNA methylase RmtB, I222===


Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3FRI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].	+	3FRI is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].

	==Reference==		==Reference==
Line 35:		Line 35:
	[[Category: N-terminal helical domain]]		[[Category: N-terminal helical domain]]
	[[Category: Plasmid]]		[[Category: Plasmid]]
		+	[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 12~~ 13:43:~~46 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 13:57:21 2010''

OCA at 10:43, 12 August 2009

OCA — Wed, 12 Aug 2009 10:43:47 GMT

←Older revision		Revision as of 10:43, 12 August 2009
Line 12:		Line 12:
	===Structure of an escherichia coli methyltransferase, I 2 2 2===		===Structure of an escherichia coli methyltransferase, I 2 2 2===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19303884}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19303884 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19303884}}

	==About this Structure==		==About this Structure==
Line 30:		Line 36:
	[[Category: Plasmid]]		[[Category: Plasmid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:40:27 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 13:43:46 2009''

OCA at 09:40, 12 August 2009

OCA — Wed, 12 Aug 2009 09:40:29 GMT

←Older revision		Revision as of 09:40, 12 August 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3fri.jpg\|left\|200px]]

-	The ~~entry 3fri~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3fri", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3fri\| PDB=3fri \| SCENE= }}

-	~~Authors: Schmitt~~, ~~E., Galimand, M., Panvert, M., Dupechez, M., Courvalin, P., Mechulam, Y.~~	+	===Structure of an escherichia coli methyltransferase, I 2 2 2===

-	Description: Structure of an escherichia coli methyltransferase, I 2 2 2

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 4 11~~:23:51 2009''	+	==About this Structure==
		+	3FRI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19303884</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Courvalin, P.]]
		+	[[Category: Dupechez, M.]]
		+	[[Category: Galimand, M.]]
		+	[[Category: Mechulam, Y.]]
		+	[[Category: Panvert, M.]]
		+	[[Category: Schmitt, E.]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Methyltransferase domain]]
		+	[[Category: N-terminal helical domain]]
		+	[[Category: Plasmid]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:40:27 2009''