3g1b - Revision history

OCA at 06:55, 6 September 2023

OCA — Wed, 06 Sep 2023 06:55:56 GMT

←Older revision		Revision as of 06:55, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3g1b' size='340' side='right'caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3g1b' size='340' side='right'caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_15252_[[caulobacter_crescentus_poindexter_1964]] Atcc 15252 [[caulobacter crescentus poindexter 1964]]~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1B FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.448Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3dnj\|3dnj]], [[3g19\|3g19]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">CC_2467, clpS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ATCC 15252 [[Caulobacter crescentus Poindexter 1964]]])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [https://pdbe.org/3g1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [https://www.ebi.ac.uk/pdbsum/3g1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [https://pdbe.org/3g1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [https://www.ebi.ac.uk/pdbsum/3g1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CLPS_CAUCR CLPS_CAUCR]~~] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/CLPS_CAUVC CLPS_CAUVC] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.[HAMAP-Rule:MF_00302]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Caulobacter vibrioides]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baker~~, T A~~]]	+	[[Category: Baker TA]]
-	[[Category: Grant~~, R A~~]]	+	[[Category: Grant RA]]
-	[[Category: Roman-Hernandez, G]]	+	[[Category: Roman-Hernandez G]]
-	[[Category: Sauer~~, R T]]~~	+	[[Category: Sauer RT]]
-	~~[[Category: Adaptor]]~~	+
-	~~[[Category: Peptide binding protein]]~~	+
-	~~[[Category: Peptide-binding protein]]~~	+
-	~~[[Category: Protein-peptide complex~~]]	+

OCA at 20:00, 20 October 2021

OCA — Wed, 20 Oct 2021 20:00:41 GMT

←Older revision		Revision as of 20:00, 20 October 2021
Line 1:		Line 1:

	==The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide==		==The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide==
-	<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='3g1b' size='340' side='right'caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cauvi Cauvi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3G1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_15252_[[caulobacter_crescentus_poindexter_1964]] Atcc 15252 [[caulobacter crescentus poindexter 1964]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dnj\|3dnj]], [[3g19\|3g19]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ~~CAUVI~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ATCC 15252 [[Caulobacter crescentus Poindexter 1964]]])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [~~http~~://pdbe.org/3g1b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3g1b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [https://pdbe.org/3g1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [https://www.ebi.ac.uk/pdbsum/3g1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CLPS_CAUCR CLPS_CAUCR]] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity).	+	[[https://www.uniprot.org/uniprot/CLPS_CAUCR CLPS_CAUCR]] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1b_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1b_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 3g1b" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3g1b" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATP-dependent Clp protease adaptor protein 3D structures\|ATP-dependent Clp protease adaptor protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cauvi~~]]	+	[[Category: Large Structures]]
	[[Category: Baker, T A]]		[[Category: Baker, T A]]
	[[Category: Grant, R A]]		[[Category: Grant, R A]]

OCA at 06:54, 1 November 2017

OCA — Wed, 01 Nov 2017 06:54:35 GMT

←Older revision		Revision as of 06:54, 1 November 2017
Line 1:		Line 1:
		+
	==The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide==		==The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide==
	<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cauce Cauce~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cauvi Cauvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ~~CAUCE~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 CAUVI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://pdbe.org/3g1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://pdbe.org/3g1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1b ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cauce~~]]	+	[[Category: Cauvi]]
	[[Category: Baker, T A]]		[[Category: Baker, T A]]
	[[Category: Grant, R A]]		[[Category: Grant, R A]]

OCA at 13:04, 9 February 2016

OCA — Tue, 09 Feb 2016 13:04:16 GMT

←Older revision		Revision as of 13:04, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Caulobacter_vibrioides Caulobacter vibrioides~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Cauce Cauce]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 ~~Caulobacter vibrioides~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 CAUCE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://pdbe.org/3g1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g1b ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3g1b" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caulobacter vibrioides~~]]	+	[[Category: Cauce]]
	[[Category: Baker, T A]]		[[Category: Baker, T A]]
	[[Category: Grant, R A]]		[[Category: Grant, R A]]

OCA at 06:59, 25 December 2014

OCA — Thu, 25 Dec 2014 06:59:52 GMT

←Older revision		Revision as of 06:59, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CLPS_CAUCR CLPS_CAUCR]] Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:22, 3 December 2014

OCA — Wed, 03 Dec 2014 10:22:41 GMT

←Older revision		Revision as of 10:22, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3g1b.~~png~~\|~~left~~\|200px]]	+	==The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide==
		+	<StructureSection load='3g1b' size='340' side='right' caption='[[3g1b]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G1B FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnj\|3dnj]], [[3g19\|3g19]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CC_2467, clpS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 Caulobacter vibrioides])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g1b RCSB], [http://www.ebi.ac.uk/pdbsum/3g1b PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1b_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The N-end rule is a conserved degradation pathway that relates the stability of a protein to its N-terminal amino acid. Here, we present crystal structures of ClpS, the bacterial N-end rule adaptor, alone and engaged with peptides containing N-terminal phenylalanine, leucine, and tryptophan. These structures, together with a previous structure of ClpS bound to an N-terminal tyrosine, illustrate the molecular basis of recognition of the complete set of primary N-end rule amino acids. In each case, the alpha-amino group and side chain of the N-terminal residue are the major determinants of recognition. The binding pocket for the N-end residue is preformed in the free adaptor, and only small adjustments are needed to accommodate N-end rule residues having substantially different sizes and shapes. M53A ClpS is known to mediate degradation of an expanded repertoire of substrates, including those with N-terminal valine or isoleucine. A structure of Met53A ClpS engaged with an N-end rule tryptophan reveals an essentially wild-type mechanism of recognition, indicating that the Met(53) side chain directly enforces specificity by clashing with and excluding beta-branched side chains. Finally, experimental and structural data suggest mechanisms that make proteins with N-terminal methionine bind very poorly to ClpS, explaining why these high-abundance proteins are not degraded via the N-end rule pathway in the cell.

-	~~{{STRUCTURE_3g1b\| PDB=3g1b \| SCENE= }}~~	+	Molecular basis of substrate selection by the N-end rule adaptor protein ClpS.,Roman-Hernandez G, Grant RA, Sauer RT, Baker TA Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8888-93. Epub 2009 May 18. PMID:19451643<ref>PMID:19451643</ref>

-	~~===The structure~~ of the ~~M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19451643}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3g1b]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019451643<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
-	[[Category: Baker, T A.]]	+	[[Category: Baker, T A]]
-	[[Category: Grant, R A.]]	+	[[Category: Grant, R A]]
-	[[Category: Roman-Hernandez, G.]]	+	[[Category: Roman-Hernandez, G]]
-	[[Category: Sauer, R T.]]	+	[[Category: Sauer, R T]]
	[[Category: Adaptor]]		[[Category: Adaptor]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Peptide-binding protein]]		[[Category: Peptide-binding protein]]
	[[Category: Protein-peptide complex]]		[[Category: Protein-peptide complex]]

OCA: Protected "3g1b" [edit=sysop:move=sysop]

OCA — Wed, 20 Feb 2013 14:40:34 GMT

Protected "3g1b" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:40, 20 February 2013

OCA at 14:40, 20 February 2013

OCA — Wed, 20 Feb 2013 14:40:30 GMT

←Older revision		Revision as of 14:40, 20 February 2013
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-	{{Seed}}
	[[Image:3g1b.png\|left\|200px]]		[[Image:3g1b.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3g1b\| PDB=3g1b \| SCENE= }}		{{STRUCTURE_3g1b\| PDB=3g1b \| SCENE= }}

	===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===		===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===

-
-	<!--
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	{{ABSTRACT_PUBMED_19451643}}		{{ABSTRACT_PUBMED_19451643}}

	==About this Structure==		==About this Structure==
-	~~3G1B~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].	+	[[3g1b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19451643~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019451643</ref><references group="xtra"/>
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
	[[Category: Baker, T A.]]		[[Category: Baker, T A.]]
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	[[Category: Peptide-binding protein]]		[[Category: Peptide-binding protein]]
	[[Category: Protein-peptide complex]]		[[Category: Protein-peptide complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 4 18:10:15 2009''

OCA at 15:10, 4 July 2009

OCA — Sat, 04 Jul 2009 15:10:15 GMT

←Older revision		Revision as of 15:10, 4 July 2009
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	===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===		===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19451643}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19451643 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19451643}}

	==About this Structure==		==About this Structure==
	3G1B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].		3G1B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19451643</ref><references group="xtra"/>
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
	[[Category: Baker, T A.]]		[[Category: Baker, T A.]]
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	[[Category: Protein-peptide complex]]		[[Category: Protein-peptide complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Jul ~~1 20~~:19:31 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 4 18:10:15 2009''

OCA at 17:14, 1 July 2009

OCA — Wed, 01 Jul 2009 17:14:41 GMT

←Older revision		Revision as of 17:14, 1 July 2009
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	===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===		===The structure of the M53A mutant of Caulobacter crescentus clpS protease adaptor protein in complex with WLFVQRDSKE peptide===

-
-	<!--
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-	(as it appears on PubMed at http://www.pubmed.gov), where 19451643 is the PubMed ID number.
-	-->
-	{{ABSTRACT_PUBMED_19451643}}

	==About this Structure==		==About this Structure==
	3G1B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].		3G1B is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1B OCA].
-
-	==Reference==
-	<ref group="xtra">PMID:19451643</ref><references group="xtra"/>
	[[Category: Caulobacter vibrioides]]		[[Category: Caulobacter vibrioides]]
	[[Category: Baker, T A.]]		[[Category: Baker, T A.]]
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	[[Category: Protein-peptide complex]]		[[Category: Protein-peptide complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 09:11:58 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 20:19:31 2009''