3g28 - Revision history

OCA at 15:35, 1 November 2023

OCA — Wed, 01 Nov 2023 15:35:12 GMT

←Older revision		Revision as of 15:35, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3g28' size='340' side='right'caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>		<StructureSection load='3g28' size='340' side='right'caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Rsv~~-~~prc Rsv~~-~~prc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G28 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus_-_Prague_C Rous sarcoma virus - Prague C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G28 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.64Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">gag ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11888 RSV-PrC])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [https://pdbe.org/3g28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [https://www.ebi.ac.uk/pdbsum/3g28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g28 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [https://pdbe.org/3g28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [https://www.ebi.ac.uk/pdbsum/3g28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g28 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).	+	[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 39:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Rsv~~-~~prc~~]]	+	[[Category: Rous sarcoma virus - Prague C]]
-	[[Category: Kingston~~, R L]]~~	+	[[Category: Kingston RL]]
-	~~[[Category: Alpha-helical bundle]]~~	+
-	~~[[Category: Capsid protein]]~~	+
-	~~[[Category: Retrovirus]]~~	+
-	~~[[Category: Viral protein]]~~	+
-	~~[[Category: Virion~~]]	+

OCA at 07:40, 10 November 2021

OCA — Wed, 10 Nov 2021 07:40:54 GMT

←Older revision		Revision as of 07:40, 10 November 2021
Line 1:		Line 1:

	==Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH==		==Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH==
-	<StructureSection load='3g28' size='340' side='right' caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>	+	<StructureSection load='3g28' size='340' side='right'caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rsv-prc Rsv-prc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3G28 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rsv-prc Rsv-prc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G28 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11888 RSV-PrC])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11888 RSV-PrC])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [~~http~~://pdbe.org/3g28 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3g28 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3g28 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [https://pdbe.org/3g28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [https://www.ebi.ac.uk/pdbsum/3g28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g28 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).	+	[[https://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Gag polyprotein\|Gag polyprotein]]	+	*[[Gag polyprotein 3D structures\|Gag polyprotein 3D structures]]
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Rsv-prc]]		[[Category: Rsv-prc]]
	[[Category: Kingston, R L]]		[[Category: Kingston, R L]]

OCA at 08:05, 5 December 2018

OCA — Wed, 05 Dec 2018 08:05:07 GMT

←Older revision		Revision as of 08:05, 5 December 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g28_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g28_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:44, 5 August 2016

OCA — Fri, 05 Aug 2016 16:44:30 GMT

←Older revision		Revision as of 16:44, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH==		==Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH==
	<StructureSection load='3g28' size='340' side='right' caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>		<StructureSection load='3g28' size='340' side='right' caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rous_sarcoma_virus Rous sarcoma virus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G28 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rsv-prc Rsv-prc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G28 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~11886 Rous sarcoma virus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11888 RSV-PrC])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [http://www.ebi.ac.uk/pdbsum/3g28 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [http://pdbe.org/3g28 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [http://www.ebi.ac.uk/pdbsum/3g28 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3g28 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g28 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3g28" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 38:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rous sarcoma virus~~]]	+	[[Category: Rsv-prc]]
	[[Category: Kingston, R L]]		[[Category: Kingston, R L]]
	[[Category: Alpha-helical bundle]]		[[Category: Alpha-helical bundle]]

OCA at 20:23, 25 December 2014

OCA — Thu, 25 Dec 2014 20:23:38 GMT

←Older revision		Revision as of 20:23, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G28 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G28 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11886 Rous sarcoma virus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11886 Rous sarcoma virus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [http://www.ebi.ac.uk/pdbsum/3g28 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [http://www.ebi.ac.uk/pdbsum/3g28 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GAG_RSVP GAG_RSVP]] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Rous sarcoma virus]]		[[Category: Rous sarcoma virus]]
-	[[Category: Kingston, R L.]]	+	[[Category: Kingston, R L]]
	[[Category: Alpha-helical bundle]]		[[Category: Alpha-helical bundle]]
	[[Category: Capsid protein]]		[[Category: Capsid protein]]

OCA at 12:39, 29 September 2014

OCA — Mon, 29 Sep 2014 12:39:42 GMT

←Older revision		Revision as of 12:39, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3g28.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH==
		+	<StructureSection load='3g28' size='340' side='right' caption='[[3g28]], [[Resolution\|resolution]] 1.64Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G28 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g0v\|3g0v]], [[3g1g\|3g1g]], [[3g1i\|3g1i]], [[3g21\|3g21]], [[3g26\|3g26]], [[3g29\|3g29]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gag ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11886 Rous sarcoma virus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g28 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g28 RCSB], [http://www.ebi.ac.uk/pdbsum/3g28 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g28_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly. In contrast, other retroviral capsid proteins, including that of Rous sarcoma virus (RSV), do not dimerize with measurable affinity. Here we show, using X-ray crystallography and other biophysical methods, that acidification causes RSV CA to dimerize in a fashion analogous to HIV CA, and that this drives capsid assembly in vitro. A pair of aspartic acid residues, located within the CTD dimer interface, explains why dimerization is linked to proton binding. Our results show that despite overarching structural similarities, the intermolecular forces responsible for forming and stabilizing the retroviral capsid differ markedly across retroviral genera. Our data further suggest that proton binding may regulate RSV capsid assembly, or modulate stability of the assembled capsid.

-	~~{{STRUCTURE_3g28\| PDB=3g28 \| SCENE= }}~~	+	Proton-linked dimerization of a retroviral capsid protein initiates capsid assembly.,Bailey GD, Hyun JK, Mitra AK, Kingston RL Structure. 2009 May 13;17(5):737-48. PMID:19446529<ref>PMID:19446529</ref>

-	~~===Crystal structure~~ of the ~~C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19446529}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3g28]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rous_sarcoma_virus Rous sarcoma virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].~~	+

	==See Also==		==See Also==
	*[[Gag polyprotein\|Gag polyprotein]]		*[[Gag polyprotein\|Gag polyprotein]]
	*[[Virus coat protein\|Virus coat protein]]		*[[Virus coat protein\|Virus coat protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019446529<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Rous sarcoma virus]]		[[Category: Rous sarcoma virus]]
	[[Category: Kingston, R L.]]		[[Category: Kingston, R L.]]

OCA at 21:04, 20 October 2012

OCA — Sat, 20 Oct 2012 21:04:25 GMT

←Older revision		Revision as of 21:04, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3g28]] is a 1 chain structure ~~of [[Gag polyprotein]]~~ with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].	+	[[3g28]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].

	==See Also==		==See Also==
	*[[Gag polyprotein\|Gag polyprotein]]		*[[Gag polyprotein\|Gag polyprotein]]
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==

OCA: Protected "3g28" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 12:30:38 GMT

Protected "3g28" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:30, 27 July 2012

OCA at 12:30, 27 July 2012

OCA — Fri, 27 Jul 2012 12:30:36 GMT

←Older revision		Revision as of 12:30, 27 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3g28.png\|left\|200px]]
-	[[Image:3g28.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3g28", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3g28\| PDB=3g28 \| SCENE= }}		{{STRUCTURE_3g28\| PDB=3g28 \| SCENE= }}

	===Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH===		===Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19446529}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19446529 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19446529}}		{{ABSTRACT_PUBMED_19446529}}

	==About this Structure==		==About this Structure==
-	~~3G28~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].	+	[[3g28]] is a 1 chain structure of [[Gag polyprotein]] with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].
		+
		+	==See Also==
		+	*[[Gag polyprotein\|Gag polyprotein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19446529~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019446529</ref><references group="xtra"/>
	[[Category: Rous sarcoma virus]]		[[Category: Rous sarcoma virus]]
	[[Category: Kingston, R L.]]		[[Category: Kingston, R L.]]
Line 31:		Line 22:
	[[Category: Viral protein]]		[[Category: Viral protein]]
	[[Category: Virion]]		[[Category: Virion]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 4 07:26:29 2009''

OCA at 04:26, 4 June 2009

OCA — Thu, 04 Jun 2009 04:26:30 GMT

←Older revision		Revision as of 04:26, 4 June 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3g28.jpg\|left\|200px]]

-	The ~~entry 3g28~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3g28", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3g28\| PDB=3g28 \| SCENE= }}

-	~~Authors~~: ~~Bailey~~, ~~G.D., Hyun, J.K., Mitra, A.K., Kingston, R.L.~~	+	===Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH===

-	Description: Crystal structure of the C-terminal domain of the Rous Sarcoma Virus capsid protein: mutant D179N, low pH

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Mar~~ 4 14:43:17 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19446529}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19446529 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19446529}}
		+
		+	==About this Structure==
		+	3G28 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G28 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19446529</ref><references group="xtra"/>
		+	[[Category: Rous sarcoma virus]]
		+	[[Category: Kingston, R L.]]
		+	[[Category: Alpha-helical bundle]]
		+	[[Category: Capsid protein]]
		+	[[Category: Retrovirus]]
		+	[[Category: Viral protein]]
		+	[[Category: Virion]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 4 07:26:29 2009''