3g2p - Revision history

OCA at 06:57, 6 September 2023

OCA — Wed, 06 Sep 2023 06:57:58 GMT

←Older revision		Revision as of 06:57, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3g2p' size='340' side='right'caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='3g2p' size='340' side='right'caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"streptomyces_orientalis"_pittenger_and_brigham_1956 "streptomyces~~ orientalis~~" pittenger and brigham 1956~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G2P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G2P FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SAH:S~~-~~ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.95Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]~~</~~div~~>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 "Streptomyces orientalis" Pittenger and Brigham 1956])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [https://pdbe.org/3g2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [https://www.ebi.ac.uk/pdbsum/3g2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g2p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [https://pdbe.org/3g2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [https://www.ebi.ac.uk/pdbsum/3g2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g2p ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O52805_AMYOR O52805_AMYOR]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces~~ orientalis ~~pittenger and brigham 1956~~]]	+	[[Category: Amycolatopsis orientalis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Structural genomic]]~~	+	[[Category: Cygler M]]
-	[[Category: Cygler, M]]	+	[[Category: Matte A]]
-	[[Category: Matte, A]]	+	[[Category: Shi R]]
-	[[Category: Shi, R]]	+
-	~~[[Category: Bsgi]]~~	+
-	~~[[Category: Glycopeptide antibiotics biosynthesis]]~~	+
-	~~[[Category: Sam-dependent methyltransferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:54, 9 March 2022

OCA — Wed, 09 Mar 2022 07:54:18 GMT

←Older revision		Revision as of 07:54, 9 March 2022
Line 1:		Line 1:

	==Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)==		==Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)==
-	<StructureSection load='3g2p' size='340' side='right' caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>	+	<StructureSection load='3g2p' size='340' side='right'caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"streptomyces_orientalis"_pittenger_and_brigham_1956 "streptomyces orientalis" pittenger and brigham 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3G2P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"streptomyces_orientalis"_pittenger_and_brigham_1956 "streptomyces orientalis" pittenger and brigham 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G2P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 "Streptomyces orientalis" Pittenger and Brigham 1956])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 "Streptomyces orientalis" Pittenger and Brigham 1956])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [~~http~~://pdbe.org/3g2p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3g2p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3g2p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [https://pdbe.org/3g2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [https://www.ebi.ac.uk/pdbsum/3g2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g2p ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g2p_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g2p_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Streptomyces orientalis pittenger and brigham 1956]]		[[Category: Streptomyces orientalis pittenger and brigham 1956]]
		+	[[Category: Large Structures]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Cygler, M]]		[[Category: Cygler, M]]

OCA at 20:18, 9 December 2016

OCA — Fri, 09 Dec 2016 20:18:51 GMT

←Older revision		Revision as of 20:18, 9 December 2016
Line 1:		Line 1:
		+
	==Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)==		==Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)==
	<StructureSection load='3g2p' size='340' side='right' caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='3g2p' size='340' side='right' caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Amycolatopsis_orientalis Amycolatopsis~~ orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G2P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_orientalis"_pittenger_and_brigham_1956 "streptomyces orientalis" pittenger and brigham 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G2P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 ~~Amycolatopsis~~ orientalis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 "Streptomyces orientalis" Pittenger and Brigham 1956])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [http://www.ebi.ac.uk/pdbsum/3g2p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [http://pdbe.org/3g2p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [http://www.ebi.ac.uk/pdbsum/3g2p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3g2p ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g2p ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3g2p" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Amycolatopsis~~ orientalis]]	+	[[Category: Streptomyces orientalis pittenger and brigham 1956]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Cygler, M]]		[[Category: Cygler, M]]

OCA at 10:05, 3 December 2014

OCA — Wed, 03 Dec 2014 10:05:27 GMT

←Older revision		Revision as of 10:05, 3 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3g2p.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)==
		+	<StructureSection load='3g2p' size='340' side='right' caption='[[3g2p]], [[Resolution\|resolution]] 2.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3g2p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G2P FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3g2m\|3g2m]], [[3g2o\|3g2o]], [[3g2q\|3g2q]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mtfA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31958 Amycolatopsis orientalis])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g2p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g2p RCSB], [http://www.ebi.ac.uk/pdbsum/3g2p PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/3g2p_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	There is a considerable interest in the modification of existing antibiotics to generate new antimicrobials. Glycopeptide antibiotics (GPAs) are effective against serious Gram-positive bacterial pathogens including methicillin-resistant Staphylococcus aureus. However, resistance to these antibiotics is becoming a serious problem requiring new strategies. We show that the Amycolatopsis orientalis (S)-adenosyl-L-methionine-dependent methyltransferase MtfA, from the vancomycin-class GPA chloroeremomycin biosynthetic pathway, catalyzes in vivo and in vitro methyl transfer to generate methylated GPA derivatives of the teicoplanin class. The crystal structure of MtfA complexed with (S)-adenosyl-L-methionine, (S)-adenosylhomocysteine, or sinefungin inhibitor, coupled with mutagenesis, identified His228 as a likely general base required for methyl transfer to the N terminus of the glycopeptide. Computational docking and molecular dynamics simulations were used to model binding of demethyl-vancomycin aglycone to MtfA. These results demonstrate its utility as a tool for engineering methylated analogs of GPAs.

-	~~{{STRUCTURE_3g2p\| PDB=3g2p \| SCENE= }}~~	+	Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.,Shi R, Lamb SS, Zakeri B, Proteau A, Cui Q, Sulea T, Matte A, Wright GD, Cygler M Chem Biol. 2009 Apr 24;16(4):401-10. PMID:19389626<ref>PMID:19389626</ref>

-	~~===Crystal Structure~~ of the ~~Glycopeptide N-methyltransferase MtfA complexed with (~~S~~)-adenosyl-L-homocysteine (SAH)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19389626}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3g2p]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019389626<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Amycolatopsis orientalis]]		[[Category: Amycolatopsis orientalis]]
-	[[Category: ~~BSGI, Montreal-Kingston Bacterial~~ Structural ~~Genomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Cygler, M.]]	+	[[Category: Cygler, M]]
-	[[Category: Matte, A.]]	+	[[Category: Matte, A]]
-	[[Category: Shi, R.]]	+	[[Category: Shi, R]]
	[[Category: Bsgi]]		[[Category: Bsgi]]
	[[Category: Glycopeptide antibiotics biosynthesis]]		[[Category: Glycopeptide antibiotics biosynthesis]]
-	[[Category: Montreal-kingston bacterial structural genomics initiative]]
	[[Category: Sam-dependent methyltransferase]]		[[Category: Sam-dependent methyltransferase]]
-	[[Category: Structural genomic]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA: Protected "3g2p" [edit=sysop:move=sysop]

OCA — Wed, 20 Feb 2013 14:19:11 GMT

Protected "3g2p" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:19, 20 February 2013

OCA at 14:19, 20 February 2013

OCA — Wed, 20 Feb 2013 14:19:07 GMT

←Older revision		Revision as of 14:19, 20 February 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3g2p.png\|left\|200px]]
-	[[Image:3g2p.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3g2p", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3g2p\| PDB=3g2p \| SCENE= }}		{{STRUCTURE_3g2p\| PDB=3g2p \| SCENE= }}

	===Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)===		===Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19389626}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19389626 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19389626}}		{{ABSTRACT_PUBMED_19389626}}

	==About this Structure==		==About this Structure==
-	~~3G2P~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA].	+	[[3g2p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19389626~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019389626</ref><references group="xtra"/>
	[[Category: Amycolatopsis orientalis]]		[[Category: Amycolatopsis orientalis]]
	[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]		[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
Line 34:		Line 22:
	[[Category: Sam-dependent methyltransferase]]		[[Category: Sam-dependent methyltransferase]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed May 6 10:29:10 2009''~~	+

OCA at 07:29, 6 May 2009

OCA — Wed, 06 May 2009 07:29:12 GMT

←Older revision		Revision as of 07:29, 6 May 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3g2p.jpg\|left\|200px]]

-	The ~~entry 3g2p~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3g2p", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3g2p\| PDB=3g2p \| SCENE= }}

-	~~Authors: Shi, R., Matte, A., Cygler, M., Montreal~~-~~Kingston Bacterial Structural Genomics Initiative~~ (~~BSGI~~)	+	===Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)===

-	Description: Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 11 11:~~10:43 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19389626}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19389626 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19389626}}
		+
		+	==About this Structure==
		+	3G2P is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Amycolatopsis_orientalis Amycolatopsis orientalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G2P OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19389626</ref><references group="xtra"/>
		+	[[Category: Amycolatopsis orientalis]]
		+	[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
		+	[[Category: Cygler, M.]]
		+	[[Category: Matte, A.]]
		+	[[Category: Shi, R.]]
		+	[[Category: Bsgi]]
		+	[[Category: Glycopeptide antibiotics biosynthesis]]
		+	[[Category: Montreal-kingston bacterial structural genomics initiative]]
		+	[[Category: Sam-dependent methyltransferase]]
		+	[[Category: Structural genomic]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 10:29:10 2009''

OCA at 09:10, 11 March 2009

OCA — Wed, 11 Mar 2009 09:10:43 GMT

←Older revision		Revision as of 09:10, 11 March 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3g2p is ON HOLD	+	The entry 3g2p is ON HOLD until Paper Publication

	Authors: Shi, R., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)		Authors: Shi, R., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
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	Description: Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)		Description: Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 18 08~~:54:27 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 11 11:10:43 2009''

OCA: New page: '''Unreleased structure''' The entry 3g2p is ON HOLD Authors: Shi, R., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Description: Crystal Str...

OCA — Wed, 18 Feb 2009 06:54:27 GMT

New page: '''Unreleased structure''' The entry 3g2p is ON HOLD Authors: Shi, R., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Description: Crystal Str...

New page

'''Unreleased structure'''

The entry 3g2p is ON HOLD

Authors: Shi, R., Matte, A., Cygler, M., Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)

Description: Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:54:27 2009''