3gcz - Revision history

OCA at 15:38, 1 November 2023

OCA — Wed, 01 Nov 2023 15:38:49 GMT

←Older revision		Revision as of 15:38, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3gcz' size='340' side='right'caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gcz' size='340' side='right'caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Yokase_virus Yokase~~ virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yokose_virus Yokose virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [~~http~~://pdbe.org/3gcz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gcz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gcz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [https://pdbe.org/3gcz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [https://www.ebi.ac.uk/pdbsum/3gcz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gcz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q7T918_9FLAV Q7T918_9FLAV]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Yokase~~ virus]]	+	[[Category: Yokose virus]]
-	[[Category: Bollati, M]]	+	[[Category: Bollati M]]
-	[[Category: Bolognesi, M]]	+	[[Category: Bolognesi M]]
-	[[Category: Mastrangelo, E]]	+	[[Category: Mastrangelo E]]
-	[[Category: Milani, M]]	+	[[Category: Milani M]]
-	~~[[Category: SPINE, Structural Proteomics in Europe]]~~	+
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Flavivirus]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Rna capping]]~~	+
-	~~[[Category: Rna replication]]~~	+
-	~~[[Category: Spine]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Structural proteomics in europe]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Viral enzyme structure~~]]	+

OCA at 10:38, 9 September 2020

OCA — Wed, 09 Sep 2020 10:38:46 GMT

←Older revision		Revision as of 10:38, 9 September 2020
Line 1:		Line 1:

	==Yokose virus Methyltransferase in complex with AdoMet==		==Yokose virus Methyltransferase in complex with AdoMet==
-	<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='3gcz' size='340' side='right'caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yokase_virus Yokase virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yokase_virus Yokase virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://pdbe.org/3gcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gcz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://pdbe.org/3gcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gcz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Yokase virus]]		[[Category: Yokase virus]]
	[[Category: Bollati, M]]		[[Category: Bollati, M]]

OCA at 05:36, 7 December 2018

OCA — Fri, 07 Dec 2018 05:36:01 GMT

←Older revision		Revision as of 05:36, 7 December 2018
Line 1:		Line 1:
		+
	==Yokose virus Methyltransferase in complex with AdoMet==		==Yokose virus Methyltransferase in complex with AdoMet==
	<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://pdbe.org/3gcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://pdbe.org/3gcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gcz ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gcz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gcz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:54, 7 February 2016

OCA — Sun, 07 Feb 2016 16:54:29 GMT

←Older revision		Revision as of 16:54, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Yokose_virus Yokose~~ virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yokase_virus Yokase virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O-)-methyltransferase mRNA (nucleoside-2'-O-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O)-methyltransferase mRNA (nucleoside-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://pdbe.org/3gcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gcz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gcz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Yokose~~ virus]]	+	[[Category: Yokase virus]]
	[[Category: Bollati, M]]		[[Category: Bollati, M]]
	[[Category: Bolognesi, M]]		[[Category: Bolognesi, M]]

OCA at 10:27, 3 December 2014

OCA — Wed, 03 Dec 2014 10:27:58 GMT

←Older revision		Revision as of 10:27, 3 December 2014
Line 1:		Line 1:
-	[[~~Image~~:3gcz.~~png\|left~~\|200px]]	+	==Yokose virus Methyltransferase in complex with AdoMet==
		+	<StructureSection load='3gcz' size='340' side='right' caption='[[3gcz]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yokose_virus Yokose virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GCZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/mRNA_(nucleoside-2'-O-)-methyltransferase mRNA (nucleoside-2'-O-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.57 2.1.1.57] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gcz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gcz RCSB], [http://www.ebi.ac.uk/pdbsum/3gcz PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gc/3gcz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Presently known flaviviruses belong to three major evolutionary branches: tick-borne viruses, mosquito-borne viruses and viruses with no known vector. Here we present the crystal structure of the Yokose virus methyltransferase at 1.7A resolution, the first structure of a methyltransferase of a Flavivirus with no known vector. Structural comparison of three methyltransferases representative of each of the Flavivirus branches shows that fold and structures are closely conserved, most differences being related to surface loops flexibility. Analysis of the conserved residues throughout all the sequenced flaviviral methyltransferases reveals that, besides the central cleft hosting the substrate and cofactor binding sites, a second, almost continuous, patch is conserved and points away from active site towards the back of the protein. The high level of structural conservation in this region could be functional for the methyltransferase/RNA interaction and stabilization of the ensuing complex.

-	~~{{STRUCTURE_3gcz\| PDB=3gcz \| SCENE= }}~~	+	Crystal structure of a methyltransferase from a no-known-vector Flavivirus.,Bollati M, Milani M, Mastrangelo E, de Lamballerie X, Canard B, Bolognesi M Biochem Biophys Res Commun. 2009 Apr 24;382(1):200-4. Epub 2009 Mar 9. PMID:19275894<ref>PMID:19275894</ref>

-	~~===Yokose virus Methyltransferase in complex with AdoMet===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19275894}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3gcz]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Yokose_virus Yokose virus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019275894<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Yokose virus]]		[[Category: Yokose virus]]
-	[[Category: Bollati, M.]]	+	[[Category: Bollati, M]]
-	[[Category: Bolognesi, M.]]	+	[[Category: Bolognesi, M]]
-	[[Category: Mastrangelo, E.]]	+	[[Category: Mastrangelo, E]]
-	[[Category: Milani, M.]]	+	[[Category: Milani, M]]
-	[[Category: SPINE, Structural Proteomics in Europe.]]	+	[[Category: SPINE, Structural Proteomics in Europe]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Flavivirus]]		[[Category: Flavivirus]]

OCA: Protected "3gcz" [edit=sysop:move=sysop]

OCA — Wed, 20 Feb 2013 14:49:08 GMT

Protected "3gcz" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:49, 20 February 2013

OCA at 14:49, 20 February 2013

OCA — Wed, 20 Feb 2013 14:49:04 GMT

←Older revision		Revision as of 14:49, 20 February 2013
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-	{{Seed}}
	[[Image:3gcz.png\|left\|200px]]		[[Image:3gcz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gcz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3gcz\| PDB=3gcz \| SCENE= }}		{{STRUCTURE_3gcz\| PDB=3gcz \| SCENE= }}

	===Yokose virus Methyltransferase in complex with AdoMet===		===Yokose virus Methyltransferase in complex with AdoMet===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19275894}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19275894 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19275894}}		{{ABSTRACT_PUBMED_19275894}}

	==About this Structure==		==About this Structure==
-	~~3GCZ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Yokose_virus Yokose virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA].	+	[[3gcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yokose_virus Yokose virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19275894~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019275894</ref><references group="xtra"/>
	[[Category: Yokose virus]]		[[Category: Yokose virus]]
	[[Category: Bollati, M.]]		[[Category: Bollati, M.]]
Line 39:		Line 27:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Structural proteomics in europe]]		[[Category: Structural proteomics in europe]]
		+	[[Category: Transferase]]
	[[Category: Viral enzyme structure]]		[[Category: Viral enzyme structure]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 8 20:10:13 2009''

OCA at 17:10, 8 April 2009

OCA — Wed, 08 Apr 2009 17:10:13 GMT

←Older revision		Revision as of 17:10, 8 April 2009
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	{{Seed}}		{{Seed}}
-	[[Image:3gcz.~~jpg~~\|left\|200px]]	+	[[Image:3gcz.png\|left\|200px]]

	<!--		<!--
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	[[Category: Viral enzyme structure]]		[[Category: Viral enzyme structure]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 25 12~~:45:35 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 8 20:10:13 2009''

OCA at 10:45, 25 March 2009

OCA — Wed, 25 Mar 2009 10:45:37 GMT

←Older revision		Revision as of 10:45, 25 March 2009
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3gcz.jpg\|left\|200px]]

-	The ~~entry 3gcz~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3gcz", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3gcz\| PDB=3gcz \| SCENE= }}

-	~~Authors: Bollati, M., Milani, M., Mastrangelo, E., Selisko, B., de Lamballerie, X., Canard, B., Bolognesi, M.~~	+	===Yokose virus Methyltransferase in complex with AdoMet===

-	Description: Yokose virus Methyltransferase in complex with AdoMet

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun~~ Mar ~~22 10~~:24:18 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19275894}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19275894 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19275894}}
		+
		+	==About this Structure==
		+	3GCZ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Yokose_virus Yokose virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCZ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19275894</ref><references group="xtra"/>
		+	[[Category: Yokose virus]]
		+	[[Category: Bollati, M.]]
		+	[[Category: Bolognesi, M.]]
		+	[[Category: Mastrangelo, E.]]
		+	[[Category: Milani, M.]]
		+	[[Category: SPINE, Structural Proteomics in Europe.]]
		+	[[Category: Atp-binding]]
		+	[[Category: Flavivirus]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Nucleotide-binding]]
		+	[[Category: Rna capping]]
		+	[[Category: Rna replication]]
		+	[[Category: Spine]]
		+	[[Category: Structural genomic]]
		+	[[Category: Structural proteomics in europe]]
		+	[[Category: Viral enzyme structure]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:45:35 2009''

OCA at 08:24, 22 March 2009

OCA — Sun, 22 Mar 2009 08:24:19 GMT

←Older revision		Revision as of 08:24, 22 March 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3gcz is ON HOLD	+	The entry 3gcz is ON HOLD until Paper Publication

	Authors: Bollati, M., Milani, M., Mastrangelo, E., Selisko, B., de Lamballerie, X., Canard, B., Bolognesi, M.		Authors: Bollati, M., Milani, M., Mastrangelo, E., Selisko, B., de Lamballerie, X., Canard, B., Bolognesi, M.
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	Description: Yokose virus Methyltransferase in complex with AdoMet		Description: Yokose virus Methyltransferase in complex with AdoMet

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Mar ~~11 11~~:11:18 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:24:18 2009''