3glm - Revision history

OCA at 08:26, 20 March 2024

OCA — Wed, 20 Mar 2024 08:26:26 GMT

←Older revision		Revision as of 08:26, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3glm' size='340' side='right'caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3glm' size='340' side='right'caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3glm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3glm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_symbiosum Clostridium symbiosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3gf3\|3gf3]], [[3gf7\|3gf7]], [[3gma\|3gma]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>gcdA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1512~~ "~~Bacteroides symbiosus~~" ~~Stevens 1956])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [https://pdbe.org/3glm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [https://www.ebi.ac.uk/pdbsum/3glm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3glm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [https://pdbe.org/3glm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [https://www.ebi.ac.uk/pdbsum/3glm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3glm ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B7TVP1_CLOSY B7TVP1_CLOSY]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3glm ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3glm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Glutaconyl-CoA decarboxylase (Gcd) couples the biotin-dependent decarboxylation of glutaconyl-CoA with the generation of an electrochemical Na(+) gradient. Sequencing of the genes encoding all subunits of the Clostridium symbiosum decarboxylase membrane complex revealed that it comprises two distinct biotin carrier subunits, GcdC(1) and GcdC(2), which differ in the length of a central alanine- and proline-rich linker domain. Co-crystallization of the decarboxylase subunit GcdA with the substrate glutaconyl-CoA, the product crotonyl-CoA, and the substrate analogue glutaryl-CoA, respectively, resulted in a high resolution model for substrate binding and catalysis revealing remarkable structural changes upon substrate binding. Unlike the GcdA structure from Acidaminococcus fermentans, these data suggest that in intact Gcd complexes, GcdA is associated as a tetramer crisscrossed by a network of solvent-filled tunnels.
-
-	An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases.,Kress D, Brugel D, Schall I, Linder D, Buckel W, Essen LO J Biol Chem. 2009 Oct 9;284(41):28401-9. Epub 2009 Aug 4. PMID:19654317<ref>PMID:19654317</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3glm" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacteroides symbiosus stevens 1956]]
-	[[Category: Glutaconyl-CoA decarboxylase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Brugel, D]]	+	[[Category: Brugel D]]
-	[[Category: Buckel, W]]	+	[[Category: Buckel W]]
-	[[Category: Essen, L O]]	+	[[Category: Essen L-O]]
-	[[Category: Kress, D]]	+	[[Category: Kress D]]
-	~~[[Category: Biotin]]~~	+
-	~~[[Category: Glutaconyl-coa decarboxylase]]~~	+
-	~~[[Category: Glutamate fermentation]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Sodium ion transport~~]]	+

OCA at 08:08, 9 March 2022

OCA — Wed, 09 Mar 2022 08:08:03 GMT

←Older revision		Revision as of 08:08, 9 March 2022
Line 1:		Line 1:

	==Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA==		==Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA==
-	<StructureSection load='3glm' size='340' side='right' caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3glm' size='340' side='right'caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3glm]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GLM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3glm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GLM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf3\|3gf3]], [[3gf7\|3gf7]], [[3gma\|3gma]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gf3\|3gf3]], [[3gf7\|3gf7]], [[3gma\|3gma]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [~~http~~://pdbe.org/3glm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3glm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3glm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [https://pdbe.org/3glm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [https://www.ebi.ac.uk/pdbsum/3glm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3glm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	[[Category: Bacteroides symbiosus stevens 1956]]		[[Category: Bacteroides symbiosus stevens 1956]]
	[[Category: Glutaconyl-CoA decarboxylase]]		[[Category: Glutaconyl-CoA decarboxylase]]
		+	[[Category: Large Structures]]
	[[Category: Brugel, D]]		[[Category: Brugel, D]]
	[[Category: Buckel, W]]		[[Category: Buckel, W]]

OCA at 05:26, 7 December 2018

OCA — Fri, 07 Dec 2018 05:26:20 GMT

←Older revision		Revision as of 05:26, 7 December 2018
Line 1:		Line 1:
		+
	==Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA==		==Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA==
	<StructureSection load='3glm' size='340' side='right' caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3glm' size='340' side='right' caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [http://pdbe.org/3glm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [http://www.ebi.ac.uk/pdbsum/3glm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [http://pdbe.org/3glm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [http://www.ebi.ac.uk/pdbsum/3glm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3glm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3glm_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3glm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:35, 7 February 2016

OCA — Sun, 07 Feb 2016 16:35:07 GMT

←Older revision		Revision as of 16:35, 7 February 2016
Line 7:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [http://www.ebi.ac.uk/pdbsum/3glm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [http://pdbe.org/3glm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [http://www.ebi.ac.uk/pdbsum/3glm PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3glm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3glm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:06, 21 December 2014

OCA — Sun, 21 Dec 2014 18:06:01 GMT

←Older revision		Revision as of 18:06, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}~~	+	==Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA==
-	===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===	+	<StructureSection load='3glm' size='340' side='right' caption='[[3glm]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19654317}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3glm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GLM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf3\|3gf3]], [[3gf7\|3gf7]], [[3gma\|3gma]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1512 "Bacteroides symbiosus" Stevens 1956])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaconyl-CoA_decarboxylase Glutaconyl-CoA decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.70 4.1.1.70] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3glm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3glm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3glm RCSB], [http://www.ebi.ac.uk/pdbsum/3glm PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gl/3glm_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutaconyl-CoA decarboxylase (Gcd) couples the biotin-dependent decarboxylation of glutaconyl-CoA with the generation of an electrochemical Na(+) gradient. Sequencing of the genes encoding all subunits of the Clostridium symbiosum decarboxylase membrane complex revealed that it comprises two distinct biotin carrier subunits, GcdC(1) and GcdC(2), which differ in the length of a central alanine- and proline-rich linker domain. Co-crystallization of the decarboxylase subunit GcdA with the substrate glutaconyl-CoA, the product crotonyl-CoA, and the substrate analogue glutaryl-CoA, respectively, resulted in a high resolution model for substrate binding and catalysis revealing remarkable structural changes upon substrate binding. Unlike the GcdA structure from Acidaminococcus fermentans, these data suggest that in intact Gcd complexes, GcdA is associated as a tetramer crisscrossed by a network of solvent-filled tunnels.

-	~~==About this Structure==~~	+	An asymmetric model for Na+-translocating glutaconyl-CoA decarboxylases.,Kress D, Brugel D, Schall I, Linder D, Buckel W, Essen LO J Biol Chem. 2009 Oct 9;284(41):28401-9. Epub 2009 Aug 4. PMID:19654317<ref>PMID:19654317</ref>
-	~~[[3glm]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3GLM OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:019654317</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bacteroides symbiosus stevens 1956]]		[[Category: Bacteroides symbiosus stevens 1956]]
	[[Category: Glutaconyl-CoA decarboxylase]]		[[Category: Glutaconyl-CoA decarboxylase]]
-	[[Category: Brugel, D.]]	+	[[Category: Brugel, D]]
-	[[Category: Buckel, W.]]	+	[[Category: Buckel, W]]
-	[[Category: Essen, L O.]]	+	[[Category: Essen, L O]]
-	[[Category: Kress, D.]]	+	[[Category: Kress, D]]
	[[Category: Biotin]]		[[Category: Biotin]]
	[[Category: Glutaconyl-coa decarboxylase]]		[[Category: Glutaconyl-coa decarboxylase]]

OCA at 08:53, 5 February 2014

OCA — Wed, 05 Feb 2014 08:53:38 GMT

←Older revision		Revision as of 08:53, 5 February 2014
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	{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}		{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}
	===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===		===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===
-	{{~~ABSTRACT_PUBMED_019654317~~}}	+	{{ABSTRACT_PUBMED_19654317}}

	==About this Structure==		==About this Structure==
-	[[3glm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_symbiosum Clostridium symbiosum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA].	+	[[3glm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacteroides_symbiosus"_stevens_1956 "bacteroides symbiosus" stevens 1956]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:019654317</ref><references group="xtra"/><references/>		<ref group="xtra">PMID:019654317</ref><references group="xtra"/><references/>
-	[[Category: ~~Clostridium symbiosum~~]]	+	[[Category: Bacteroides symbiosus stevens 1956]]
	[[Category: Glutaconyl-CoA decarboxylase]]		[[Category: Glutaconyl-CoA decarboxylase]]
	[[Category: Brugel, D.]]		[[Category: Brugel, D.]]

OCA at 09:32, 27 March 2013

OCA — Wed, 27 Mar 2013 09:32:34 GMT

←Older revision		Revision as of 09:32, 27 March 2013
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-	[[Image:3glm.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3glm", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}		{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}
-
	===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===		===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_019654317}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 019654317 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_019654317}}		{{ABSTRACT_PUBMED_019654317}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019654317</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019654317</ref><references group="xtra"/><references/>
	[[Category: Clostridium symbiosum]]		[[Category: Clostridium symbiosum]]
	[[Category: Glutaconyl-CoA decarboxylase]]		[[Category: Glutaconyl-CoA decarboxylase]]

OCA: Protected "3glm" [edit=sysop:move=sysop]

OCA — Thu, 26 May 2011 11:25:11 GMT

Protected "3glm" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:25, 26 May 2011

OCA at 11:25, 26 May 2011

OCA — Thu, 26 May 2011 11:25:08 GMT

←Older revision		Revision as of 11:25, 26 May 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3glm.png\|left\|200px]]

-	The ~~entry 3glm~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3glm", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3glm\| PDB=3glm \| SCENE= }}

-	~~Authors: Kress, D., Bruegel, D., Schall, I., Linder, D., Buckel, W., Essen, L.~~-O.	+	===Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA===

-	Description: Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Apr 15 09~~:54:~~44 2009''~~	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_019654317}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 019654317 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_019654317}}
		+
		+	==About this Structure==
		+	[[3glm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_symbiosum Clostridium symbiosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GLM OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:019654317</ref><references group="xtra"/>
		+	[[Category: Clostridium symbiosum]]
		+	[[Category: Glutaconyl-CoA decarboxylase]]
		+	[[Category: Brugel, D.]]
		+	[[Category: Buckel, W.]]
		+	[[Category: Essen, L O.]]
		+	[[Category: Kress, D.]]
		+	[[Category: Biotin]]
		+	[[Category: Glutaconyl-coa decarboxylase]]
		+	[[Category: Glutamate fermentation]]
		+	[[Category: Lyase]]
		+	[[Category: Sodium ion transport]]

OCA at 06:54, 15 April 2009

OCA — Wed, 15 Apr 2009 06:54:45 GMT

←Older revision		Revision as of 06:54, 15 April 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3glm is ON HOLD	+	The entry 3glm is ON HOLD until Paper Publication

-	Authors: Kress, ~~Daniel~~, Bruegel, ~~Daniela~~, Buckel, ~~Wolfgang~~, Essen, ~~Lars~~-~~Oliver~~	+	Authors: Kress, D., Bruegel, D., Schall, I., Linder, D., Buckel, W., Essen, L.-O.

	Description: Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA		Description: Glutaconyl-coA decarboxylase A subunit from Clostridium symbiosum co-crystallized with crotonyl-coA

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 25 12~~:17:16 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 15 09:54:44 2009''