3gng - Revision history

OCA at 15:42, 1 November 2023

OCA — Wed, 01 Nov 2023 15:42:56 GMT

←Older revision		Revision as of 15:42, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3gng' size='340' side='right'caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3gng' size='340' side='right'caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GNG FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3gf5\|3gf5]], [[3gnf\|3gnf]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">Mvp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10090 LK3 transgenic mice])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [https://pdbe.org/3gng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [https://www.ebi.ac.uk/pdbsum/3gng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gng ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [https://pdbe.org/3gng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [https://www.ebi.ac.uk/pdbsum/3gng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gng ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).	+	[https://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Casanas, A]]	+	[[Category: Casanas A]]
-	[[Category: Caston~~, J R~~]]	+	[[Category: Caston JR]]
-	[[Category: Fita, I]]	+	[[Category: Fita I]]
-	[[Category: Querol-Audi, J]]	+	[[Category: Querol-Audi J]]
-	[[Category: Uson, I]]	+	[[Category: Uson I]]
-	[[Category: Verdaguer, N]]	+	[[Category: Verdaguer N]]
-	~~[[Category: Beta sheet]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Ribonucleoprotein]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 07:49, 16 March 2022

OCA — Wed, 16 Mar 2022 07:49:45 GMT

←Older revision		Revision as of 07:49, 16 March 2022
Line 1:		Line 1:

	==P21B crystal structure of R1-R7 of Murine MVP==		==P21B crystal structure of R1-R7 of Murine MVP==
-	<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3gng' size='340' side='right'caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GNG FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gf5\|3gf5]], [[3gnf\|3gnf]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [~~http~~://pdbe.org/3gng PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gng PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gng ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [https://pdbe.org/3gng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [https://www.ebi.ac.uk/pdbsum/3gng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gng ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).	+	[[https://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Casanas, A]]		[[Category: Casanas, A]]

OCA at 05:18, 7 December 2018

OCA — Fri, 07 Dec 2018 05:18:18 GMT

←Older revision		Revision as of 05:18, 7 December 2018
Line 1:		Line 1:
		+
	==P21B crystal structure of R1-R7 of Murine MVP==		==P21B crystal structure of R1-R7 of Murine MVP==
	<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://pdbe.org/3gng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://pdbe.org/3gng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gng ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/3gng_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/3gng_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:19, 7 February 2016

OCA — Sun, 07 Feb 2016 22:19:36 GMT

←Older revision		Revision as of 22:19, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GNG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GNG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://pdbe.org/3gng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gng ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gng" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Casanas, A]]		[[Category: Casanas, A]]
	[[Category: Caston, J R]]		[[Category: Caston, J R]]

OCA at 18:35, 24 December 2014

OCA — Wed, 24 Dec 2014 18:35:03 GMT

←Older revision		Revision as of 18:35, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MVP_MOUSE MVP_MOUSE]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:51, 8 December 2014

OCA — Mon, 08 Dec 2014 08:51:29 GMT

←Older revision		Revision as of 08:51, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3gng.~~png~~\|~~left~~\|200px]]	+	==P21B crystal structure of R1-R7 of Murine MVP==
		+	<StructureSection load='3gng' size='340' side='right' caption='[[3gng]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GNG FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gf5\|3gf5]], [[3gnf\|3gnf]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Mvp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gng RCSB], [http://www.ebi.ac.uk/pdbsum/3gng PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/3gng_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Vaults are ubiquitous ribonucleoprotein complexes involved in a diversity of cellular processes, including multidrug resistance, transport mechanisms and signal transmission. The vault particle shows a barrel-shaped structure organized in two identical moieties, each consisting of 39 copies of the major vault protein MVP. Earlier data indicated that vault halves can dissociate at acidic pH. The crystal structure of the vault particle solved at 8 A resolution, together with the 2.1-A structure of the seven N-terminal domains (R1-R7) of MVP, reveal the interactions governing vault association and provide an explanation for a reversible dissociation induced by low pH. The structural comparison with the recently published 3.5 A model shows major discrepancies, both in the main chain tracing and in the side chain assignment of the two terminal domains R1 and R2.

-	~~{{STRUCTURE_3gng\| PDB=3gng \| SCENE= }}~~	+	The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP.,Querol-Audi J, Casanas A, Uson I, Luque D, Caston JR, Fita I, Verdaguer N EMBO J. 2009 Nov 4;28(21):3450-7. Epub 2009 Sep 24. PMID:19779459<ref>PMID:19779459</ref>

-	~~===P21B crystal structure~~ of ~~R1-R7 of Murine MVP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19779459}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3gng]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019779459<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Casanas, A.]]	+	[[Category: Casanas, A]]
-	[[Category: Caston, J R.]]	+	[[Category: Caston, J R]]
-	[[Category: Fita, I.]]	+	[[Category: Fita, I]]
-	[[Category: Querol-Audi, J.]]	+	[[Category: Querol-Audi, J]]
-	[[Category: Uson, I.]]	+	[[Category: Uson, I]]
-	[[Category: Verdaguer, N.]]	+	[[Category: Verdaguer, N]]
	[[Category: Beta sheet]]		[[Category: Beta sheet]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA: Protected "3gng" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2013 15:22:53 GMT

Protected "3gng" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:22, 27 February 2013

OCA at 15:22, 27 February 2013

OCA — Wed, 27 Feb 2013 15:22:51 GMT

←Older revision		Revision as of 15:22, 27 February 2013
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-	{{Seed}}
	[[Image:3gng.png\|left\|200px]]		[[Image:3gng.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gng", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_3gng\| PDB=3gng \| SCENE= }}		{{STRUCTURE_3gng\| PDB=3gng \| SCENE= }}

	===P21B crystal structure of R1-R7 of Murine MVP===		===P21B crystal structure of R1-R7 of Murine MVP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19779459}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_19779459}}		{{ABSTRACT_PUBMED_19779459}}

	==About this Structure==		==About this Structure==
-	~~3GNG~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA].	+	[[3gng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19779459~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019779459</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Casanas, A.]]		[[Category: Casanas, A.]]
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	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
	[[Category: Structural protein]]		[[Category: Structural protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:31 2010''

OCA at 06:11, 22 December 2010

OCA — Wed, 22 Dec 2010 06:11:55 GMT

←Older revision		Revision as of 06:11, 22 December 2010
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	[[Category: Uson, I.]]		[[Category: Uson, I.]]
	[[Category: Verdaguer, N.]]		[[Category: Verdaguer, N.]]
-	[[Category: Acetylation]]
	[[Category: Beta sheet]]		[[Category: Beta sheet]]
-	[[Category: Cytoplasm]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jan 28 14~~:40:37 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:31 2010''

OCA at 12:40, 28 January 2010

OCA — Thu, 28 Jan 2010 12:40:37 GMT

←Older revision		Revision as of 12:40, 28 January 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3gng.~~jpg~~\|left\|200px]]	+	[[Image:3gng.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	3GNG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA].	+	3GNG is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNG OCA].

	==Reference==		==Reference==
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	[[Category: Structural protein]]		[[Category: Structural protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Nov 11 22~~:23:~~52 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:40:37 2010''