3gsk - Revision history

OCA at 09:56, 21 February 2024

OCA — Wed, 21 Feb 2024 09:56:26 GMT

←Older revision		Revision as of 09:56, 21 February 2024
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [https://pdbe.org/3gsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [https://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [https://pdbe.org/3gsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [https://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Two crystal structures of Delta-Rh(bpy)(2)(chrysi)(3+) (chrysi is 5,6-chrysenequinone diimine) bound to the oligonucleotide duplex 5'-CGGAAATTACCG-3' containing two adenosine-adenosine mismatches (italics) through metalloinsertion were determined. Diffraction quality crystals with two different space groups (P3(2)21 and P4(3)2(1)2) were obtained under very similar crystallization conditions. In both structures, the bulky rhodium complex inserts into the two mismatched sites from the minor groove side, ejecting the mismatched bases into the major groove. The conformational changes are localized to the mismatched site; the metal complex replaces the mismatched base pair without an increase in base pair rise. The expansive metal complex is accommodated in the duplex by a slight opening in the phosphodiester backbone; all sugars retain a C2'-endo puckering, and flanking base pairs neither stretch nor shear. The structures differ, however, in that in one of the structures, an additional metal complex is bound by intercalation from the major groove at the central 5'-AT-3' step. We conclude that this additional metal complex is intercalated into this central step because of crystal packing forces. The structures described here of Delta-Rh(bpy)(2)(chrysi)(3+) bound to thermodynamically destabilized AA mismatches share critical features with binding by metalloinsertion in two other oligonucleotides containing different single-base mismatches. These results underscore the generality of metalloinsertion as a new mode of noncovalent binding by small molecules with a DNA duplex.
-
-	A bulky rhodium complex bound to an adenosine-adenosine DNA mismatch: general architecture of the metalloinsertion binding mode.,Zeglis BM, Pierre VC, Kaiser JT, Barton JK Biochemistry. 2009 May 26;48(20):4247-53. PMID:19374348<ref>PMID:19374348</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3gsk" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:55, 20 December 2023

OCA — Wed, 20 Dec 2023 12:55:06 GMT

←Older revision		Revision as of 12:55, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GSK FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GSK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2o1i\|2o1i]], [[3gsj\|3gsj]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [https://pdbe.org/3gsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [https://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [https://pdbe.org/3gsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [https://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Barton~~, J K~~]]	+	[[Category: Barton JK]]
-	[[Category: Kaiser~~, J T~~]]	+	[[Category: Kaiser JT]]
-	[[Category: Pierre~~, V C~~]]	+	[[Category: Pierre VC]]
-	[[Category: Zeglis~~, B M]]~~	+	[[Category: Zeglis BM]]
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Dna mismatch]]~~	+
-	~~[[Category: Dna recognition]]~~	+
-	~~[[Category: Metallointercalator~~]]	+

OCA at 07:53, 16 March 2022

OCA — Wed, 16 Mar 2022 07:53:48 GMT

←Older revision		Revision as of 07:53, 16 March 2022
Line 3:		Line 3:
	<StructureSection load='3gsk' size='340' side='right'caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3gsk' size='340' side='right'caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GSK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GSK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2o1i\|2o1i]], [[3gsj\|3gsj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2o1i\|2o1i]], [[3gsj\|3gsj]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [~~http~~://pdbe.org/3gsk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [https://pdbe.org/3gsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [https://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:02, 25 December 2019

OCA — Wed, 25 Dec 2019 14:02:58 GMT

←Older revision		Revision as of 14:02, 25 December 2019
Line 1:		Line 1:

	==A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch==		==A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch==
-	<StructureSection load='3gsk' size='340' side='right' caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='3gsk' size='340' side='right'caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GSK FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GSK FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Barton, J K]]		[[Category: Barton, J K]]
	[[Category: Kaiser, J T]]		[[Category: Kaiser, J T]]

OCA at 20:24, 9 December 2016

OCA — Fri, 09 Dec 2016 20:24:37 GMT

←Older revision		Revision as of 20:24, 9 December 2016
Line 1:		Line 1:
		+
	==A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch==		==A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch==
	<StructureSection load='3gsk' size='340' side='right' caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3gsk' size='340' side='right' caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2o1i\|2o1i]], [[3gsj\|3gsj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2o1i\|2o1i]], [[3gsj\|3gsj]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [http://www.ebi.ac.uk/pdbsum/3gsk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [http://pdbe.org/3gsk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [http://www.ebi.ac.uk/pdbsum/3gsk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gsk ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gsk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:24, 8 December 2014

OCA — Mon, 08 Dec 2014 09:24:39 GMT

←Older revision		Revision as of 09:24, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3gsk.~~png~~\|~~left~~\|~~200px~~]]	+	==A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch==
		+	<StructureSection load='3gsk' size='340' side='right' caption='[[3gsk]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GSK FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=R1C:BIS(2,2-BIPYRIDINE-KAPPA~2~N~1~,N~1~)[CHRYSENE-5,6-DIIMINATO(2-)-KAPPA~2~N,N]RHODIUM(4+)'>R1C</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2o1i\|2o1i]], [[3gsj\|3gsj]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gsk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gsk RCSB], [http://www.ebi.ac.uk/pdbsum/3gsk PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two crystal structures of Delta-Rh(bpy)(2)(chrysi)(3+) (chrysi is 5,6-chrysenequinone diimine) bound to the oligonucleotide duplex 5'-CGGAAATTACCG-3' containing two adenosine-adenosine mismatches (italics) through metalloinsertion were determined. Diffraction quality crystals with two different space groups (P3(2)21 and P4(3)2(1)2) were obtained under very similar crystallization conditions. In both structures, the bulky rhodium complex inserts into the two mismatched sites from the minor groove side, ejecting the mismatched bases into the major groove. The conformational changes are localized to the mismatched site; the metal complex replaces the mismatched base pair without an increase in base pair rise. The expansive metal complex is accommodated in the duplex by a slight opening in the phosphodiester backbone; all sugars retain a C2'-endo puckering, and flanking base pairs neither stretch nor shear. The structures differ, however, in that in one of the structures, an additional metal complex is bound by intercalation from the major groove at the central 5'-AT-3' step. We conclude that this additional metal complex is intercalated into this central step because of crystal packing forces. The structures described here of Delta-Rh(bpy)(2)(chrysi)(3+) bound to thermodynamically destabilized AA mismatches share critical features with binding by metalloinsertion in two other oligonucleotides containing different single-base mismatches. These results underscore the generality of metalloinsertion as a new mode of noncovalent binding by small molecules with a DNA duplex.

-	~~{{STRUCTURE_3gsk\| PDB=3gsk \| SCENE= }}~~	+	A bulky rhodium complex bound to an adenosine-adenosine DNA mismatch: general architecture of the metalloinsertion binding mode.,Zeglis BM, Pierre VC, Kaiser JT, Barton JK Biochemistry. 2009 May 26;48(20):4247-53. PMID:19374348<ref>PMID:19374348</ref>

-	~~===A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19374348}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3gsk]] is~~ a ~~2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3GSK OCA].~~	+	</StructureSection>
-		+	[[Category: Barton, J K]]
-	==~~Reference~~==	+	[[Category: Kaiser, J T]]
-	<~~ref group="xtra">PMID:019374348<~~/~~ref~~><~~references group="xtra"~~/>	+	[[Category: Pierre, V C]]
-	[[Category: Barton, J K.]]	+	[[Category: Zeglis, B M]]
-	[[Category: Kaiser, J T.]]	+
-	[[Category: Pierre, V C.]]	+
-	[[Category: Zeglis, B M.]]	+
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Dna mismatch]]		[[Category: Dna mismatch]]
	[[Category: Dna recognition]]		[[Category: Dna recognition]]
	[[Category: Metallointercalator]]		[[Category: Metallointercalator]]

OCA: Protected "3gsk" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2013 15:24:34 GMT

Protected "3gsk" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:24, 27 February 2013

OCA at 15:24, 27 February 2013

OCA — Wed, 27 Feb 2013 15:24:29 GMT

←Older revision		Revision as of 15:24, 27 February 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3gsk.png\|left\|200px]]		[[Image:3gsk.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gsk", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3gsk\| PDB=3gsk \| SCENE= }}		{{STRUCTURE_3gsk\| PDB=3gsk \| SCENE= }}

	===A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch===		===A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19374348}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19374348 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19374348}}		{{ABSTRACT_PUBMED_19374348}}

	==About this Structure==		==About this Structure==
-	~~3GSK~~ is a 2 ~~chains~~ structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA].	+	[[3gsk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19374348~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019374348</ref><references group="xtra"/>
	[[Category: Barton, J K.]]		[[Category: Barton, J K.]]
	[[Category: Kaiser, J T.]]		[[Category: Kaiser, J T.]]
	[[Category: Pierre, V C.]]		[[Category: Pierre, V C.]]
	[[Category: Zeglis, B M.]]		[[Category: Zeglis, B M.]]
		+	[[Category: Dna]]
	[[Category: Dna mismatch]]		[[Category: Dna mismatch]]
	[[Category: Dna recognition]]		[[Category: Dna recognition]]
	[[Category: Metallointercalator]]		[[Category: Metallointercalator]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 3 09:10:27 2009''

OCA at 06:10, 3 June 2009

OCA — Wed, 03 Jun 2009 06:10:28 GMT

←Older revision		Revision as of 06:10, 3 June 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3gsk.~~jpg~~\|left\|200px]]	+	[[Image:3gsk.png\|left\|200px]]

	<!--		<!--
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	[[Category: Metallointercalator]]		[[Category: Metallointercalator]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 20 17~~:15:42 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 3 09:10:27 2009''

OCA at 14:15, 20 May 2009

OCA — Wed, 20 May 2009 14:15:43 GMT

←Older revision		Revision as of 14:15, 20 May 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3gsk.jpg\|left\|200px]]

-	The ~~entry 3gsk~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3gsk", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3gsk\| PDB=3gsk \| SCENE= }}

-	~~Authors: Zeglis, B.M., Pierre, V.C., Kaiser, J.T., Barton, J.K.~~	+	===A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch===

-	Description: A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Apr 15 09~~:57:01 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19374348}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19374348 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19374348}}
		+
		+	==About this Structure==
		+	3GSK is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GSK OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19374348</ref><references group="xtra"/>
		+	[[Category: Barton, J K.]]
		+	[[Category: Kaiser, J T.]]
		+	[[Category: Pierre, V C.]]
		+	[[Category: Zeglis, B M.]]
		+	[[Category: Dna mismatch]]
		+	[[Category: Dna recognition]]
		+	[[Category: Metallointercalator]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:15:42 2009''