3gyz - Revision history

OCA at 19:21, 29 May 2024

OCA — Wed, 29 May 2024 19:21:01 GMT

←Older revision		Revision as of 19:21, 29 May 2024
Line 3:		Line 3:
	<StructureSection load='3gyz' size='340' side='right'caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3gyz' size='340' side='right'caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3gz1\|3gz1]], [[3gz2\|3gz2]]~~</~~div~~><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">ipgC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [https://pdbe.org/3gyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [https://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [https://pdbe.org/3gyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [https://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.	+	[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Shigella paradysenteriae weldin 1927]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Kolbe, M~~]]	+	[[Category: Shigella flexneri]]
-	[[Category: ~~Lokareddy, R K]]~~	+	[[Category: Kolbe M]]
-	~~[[Category: Lunelli,~~ M]]	+	[[Category: Lokareddy RK]]
-	[[Category: ~~Zychlinsky, A~~]]	+	[[Category: Lunelli M]]
-	[[Category: ~~Asymmetric homodimer~~]]	+	[[Category: Zychlinsky A]]
-	[[Category: ~~Chaperone]]~~	+
-	~~[[Category: Tetratricopeptide repeat]]~~	+
-	~~[[Category: Tpr]]~~	+
-	~~[[Category: Virulence~~]]	+

OCA at 07:42, 10 November 2021

OCA — Wed, 10 Nov 2021 07:42:45 GMT

←Older revision		Revision as of 07:42, 10 November 2021
Line 1:		Line 1:

	==Crystal structure of IpgC from Shigella flexneri==		==Crystal structure of IpgC from Shigella flexneri==
-	<StructureSection load='3gyz' size='340' side='right' caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='3gyz' size='340' side='right'caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gz1\|3gz1]], [[3gz2\|3gz2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gz1\|3gz1]], [[3gz2\|3gz2]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ipgC ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ipgC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [~~http~~://pdbe.org/3gyz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [https://pdbe.org/3gyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [https://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.	+	[[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Shigella paradysenteriae weldin 1927]]		[[Category: Shigella paradysenteriae weldin 1927]]
		+	[[Category: Large Structures]]
	[[Category: Kolbe, M]]		[[Category: Kolbe, M]]
	[[Category: Lokareddy, R K]]		[[Category: Lokareddy, R K]]

OCA at 05:58, 7 December 2018

OCA — Fri, 07 Dec 2018 05:58:25 GMT

←Older revision		Revision as of 05:58, 7 December 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:22, 4 August 2016

OCA — Thu, 04 Aug 2016 22:22:08 GMT

←Older revision		Revision as of 22:22, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of IpgC from Shigella flexneri==		==Crystal structure of IpgC from Shigella flexneri==
	<StructureSection load='3gyz' size='340' side='right' caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='3gyz' size='340' side='right' caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Shigella_flexneri Shigella flexneri~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gz1\|3gz1]], [[3gz2\|3gz2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gz1\|3gz1]], [[3gz2\|3gz2]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ipgC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 Shigella ~~flexneri~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ipgC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://pdbe.org/3gyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gyz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gyz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Shigella ~~flexneri~~]]	+	[[Category: Shigella paradysenteriae weldin 1927]]
	[[Category: Kolbe, M]]		[[Category: Kolbe, M]]
	[[Category: Lokareddy, R K]]		[[Category: Lokareddy, R K]]

OCA at 13:36, 25 December 2014

OCA — Thu, 25 Dec 2014 13:36:47 GMT

←Older revision		Revision as of 13:36, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:33, 8 December 2014

OCA — Mon, 08 Dec 2014 09:33:30 GMT

←Older revision		Revision as of 09:33, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3gyz.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of IpgC from Shigella flexneri==
		+	<StructureSection load='3gyz' size='340' side='right' caption='[[3gyz]], [[Resolution\|resolution]] 2.15Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gz1\|3gz1]], [[3gz2\|3gz2]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ipgC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 Shigella flexneri])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The delivery of virulence factors into host cells through type III secretion systems is essential for enterobacterial pathogenesis. Molecular chaperones bind specifically to virulence factors in the bacterial cytosol before secretion. Invasion plasmid gene C (IpgC) is a chaperone that binds 2 essential virulence factors of Shigella: invasion plasmid antigens (Ipa) B and C. Here, we report the crystal structure of IpgC alone and in complex with the chaperone binding domain (CBD) of IpaB. The chaperone captures the CBD in an extended conformation that is stabilized by conserved residues lining the cleft. Analysis of the cocrystal structure reveals a sequence motif that is functional in the IpaB translocator class from different bacteria as determined by isothermal titration calorimetry. Our results show how translocators are chaperoned and may allow the design of inhibitors of enterobacterial diseases.

-	~~{{STRUCTURE_3gyz\| PDB=3gyz \| SCENE= }}~~	+	IpaB-IpgC interaction defines binding motif for type III secretion translocator.,Lunelli M, Lokareddy RK, Zychlinsky A, Kolbe M Proc Natl Acad Sci U S A. 2009 May 28. PMID:19478065<ref>PMID:19478065</ref>

-	~~===Crystal structure~~ of ~~IpgC from Shigella flexneri===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19478065}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3gyz]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Shigella_flexneri Shigella flexneri]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019478065<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Shigella flexneri]]		[[Category: Shigella flexneri]]
-	[[Category: Kolbe, M.]]	+	[[Category: Kolbe, M]]
-	[[Category: Lokareddy, R K.]]	+	[[Category: Lokareddy, R K]]
-	[[Category: Lunelli, M.]]	+	[[Category: Lunelli, M]]
-	[[Category: Zychlinsky, A.]]	+	[[Category: Zychlinsky, A]]
	[[Category: Asymmetric homodimer]]		[[Category: Asymmetric homodimer]]
	[[Category: Chaperone]]		[[Category: Chaperone]]

OCA: Protected "3gyz" [edit=sysop:move=sysop]

OCA — Wed, 27 Feb 2013 15:36:08 GMT

Protected "3gyz" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:36, 27 February 2013

OCA at 15:36, 27 February 2013

OCA — Wed, 27 Feb 2013 15:36:06 GMT

←Older revision		Revision as of 15:36, 27 February 2013
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-	{{Seed}}
	[[Image:3gyz.png\|left\|200px]]		[[Image:3gyz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gyz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3gyz\| PDB=3gyz \| SCENE= }}		{{STRUCTURE_3gyz\| PDB=3gyz \| SCENE= }}

	===Crystal structure of IpgC from Shigella flexneri===		===Crystal structure of IpgC from Shigella flexneri===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19478065}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19478065 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19478065}}		{{ABSTRACT_PUBMED_19478065}}

	==About this Structure==		==About this Structure==
-	~~3GYZ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA].	+	[[3gyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19478065~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019478065</ref><references group="xtra"/>
	[[Category: Shigella flexneri]]		[[Category: Shigella flexneri]]
	[[Category: Kolbe, M.]]		[[Category: Kolbe, M.]]
Line 31:		Line 19:
	[[Category: Asymmetric homodimer]]		[[Category: Asymmetric homodimer]]
	[[Category: Chaperone]]		[[Category: Chaperone]]
-	[[Category: Cytoplasm]]
-	[[Category: Plasmid]]
	[[Category: Tetratricopeptide repeat]]		[[Category: Tetratricopeptide repeat]]
	[[Category: Tpr]]		[[Category: Tpr]]
	[[Category: Virulence]]		[[Category: Virulence]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 08:24:31 2009''

OCA at 05:24, 25 June 2009

OCA — Thu, 25 Jun 2009 05:24:33 GMT

←Older revision		Revision as of 05:24, 25 June 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3gyz.~~jpg~~\|left\|200px]]	+	[[Image:3gyz.png\|left\|200px]]

	<!--		<!--
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	[[Category: Virulence]]		[[Category: Virulence]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Jun ~~17 10~~:11:54 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 25 08:24:31 2009''

OCA at 07:11, 17 June 2009

OCA — Wed, 17 Jun 2009 07:11:59 GMT

←Older revision		Revision as of 07:11, 17 June 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3gyz.jpg\|left\|200px]]

-	The ~~entry 3gyz~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3gyz", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3gyz\| PDB=3gyz \| SCENE= }}

-	~~Authors: Lunelli, M., Lokareddy, R.K., Zychlinsky, A., Kolbe, M.~~	+	===Crystal structure of IpgC from Shigella flexneri===

-	Description: Crystal structure of IpgC from Shigella flexneri

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Apr 15~~ 10:00:09 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19478065}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19478065 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19478065}}
		+
		+	==About this Structure==
		+	3GYZ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19478065</ref><references group="xtra"/>
		+	[[Category: Shigella flexneri]]
		+	[[Category: Kolbe, M.]]
		+	[[Category: Lokareddy, R K.]]
		+	[[Category: Lunelli, M.]]
		+	[[Category: Zychlinsky, A.]]
		+	[[Category: Asymmetric homodimer]]
		+	[[Category: Chaperone]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Plasmid]]
		+	[[Category: Tetratricopeptide repeat]]
		+	[[Category: Tpr]]
		+	[[Category: Virulence]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 17 10:11:54 2009''