3gzt - Revision history

OCA at 07:59, 16 March 2022

OCA — Wed, 16 Mar 2022 07:59:16 GMT

←Older revision		Revision as of 07:59, 16 March 2022
Line 3:		Line 3:
	<SX load='3gzt' size='340' side='right' viewer='molstar' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>		<SX load='3gzt' size='340' side='right' viewer='molstar' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3GZT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GZT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gzu\|3gzu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [~~http~~://pdbe.org/3gzt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gzt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gzt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [https://pdbe.org/3gzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [https://www.ebi.ac.uk/pdbsum/3gzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gzt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/VP7_ROTRH VP7_ROTRH]] Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved (By similarity).	+	[[https://www.uniprot.org/uniprot/VP7_ROTRH VP7_ROTRH]] Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:21, 10 April 2020

OCA — Fri, 10 Apr 2020 17:21:53 GMT

←Older revision		Revision as of 17:21, 10 April 2020
Line 3:		Line 3:
	<SX load='3gzt' size='340' side='right' viewer='molstar' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>		<SX load='3gzt' size='340' side='right' viewer='molstar' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GZT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3GZT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://pdbe.org/3gzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gzt ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://pdbe.org/3gzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gzt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Virus coat ~~protein~~\|Virus coat ~~protein~~]]	+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:24, 5 March 2020

OCA — Thu, 05 Mar 2020 04:24:49 GMT

←Older revision		Revision as of 04:24, 5 March 2020
Line 1:		Line 1:

	==VP7 recoated rotavirus DLP==		==VP7 recoated rotavirus DLP==
-	<~~StructureSection~~ load='3gzt' size='340' side='right' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>	+	<SX load='3gzt' size='340' side='right' viewer='molstar' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GZT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GZT FirstGlance]. <br>
Line 35:		Line 35:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Rhesus rotavirus]]		[[Category: Rhesus rotavirus]]
	[[Category: Chen, J Z]]		[[Category: Chen, J Z]]

OCA at 05:20, 7 December 2018

OCA — Fri, 07 Dec 2018 05:20:32 GMT

←Older revision		Revision as of 05:20, 7 December 2018
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/3gzt_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/3gzt_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:48, 11 August 2016

OCA — Thu, 11 Aug 2016 18:48:13 GMT

←Older revision		Revision as of 18:48, 11 August 2016
Line 1:		Line 1:
		+
	==VP7 recoated rotavirus DLP==		==VP7 recoated rotavirus DLP==
	<StructureSection load='3gzt' size='340' side='right' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>		<StructureSection load='3gzt' size='340' side='right' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://pdbe.org/3gzt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gzt ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VP7_ROTRH VP7_ROTRH]] Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 15:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gzt ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3gzt" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:01, 20 January 2015

OCA — Tue, 20 Jan 2015 09:01:33 GMT

←Older revision		Revision as of 09:01, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GZT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GZT FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Rhesus rotavirus]]		[[Category: Rhesus rotavirus]]
-	[[Category: Chen, J Z.]]	+	[[Category: Chen, J Z]]
-	[[Category: Grigorieff, N.]]	+	[[Category: Grigorieff, N]]
-	[[Category: Harrison, S C.]]	+	[[Category: Harrison, S C]]
-	[[Category: Settembre, E C~~.]]~~	+	[[Category: Settembre, E C]]
-	~~[[Category: 7rp~~]]	+
	[[Category: Capsid protein]]		[[Category: Capsid protein]]
	[[Category: Disulfide bond]]		[[Category: Disulfide bond]]

OCA at 12:52, 29 September 2014

OCA — Mon, 29 Sep 2014 12:52:39 GMT

←Older revision		Revision as of 12:52, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3gzt.~~png~~\|~~left~~\|200px]]	+	==VP7 recoated rotavirus DLP==
		+	<StructureSection load='3gzt' size='340' side='right' caption='[[3gzt]], [[Resolution\|resolution]] 3.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GZT FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gzu\|3gzu]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gzt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gzt RCSB], [http://www.ebi.ac.uk/pdbsum/3gzt PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gz/3gzt_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rotaviruses, major causes of childhood gastroenteritis, are nonenveloped, icosahedral particles with double-strand RNA genomes. By the use of electron cryomicroscopy and single-particle reconstruction, we have visualized a rotavirus particle comprising the inner capsid coated with the trimeric outer-layer protein, VP7, at a resolution (4 A) comparable with that of X-ray crystallography. We have traced the VP7 polypeptide chain, including parts not seen in its X-ray crystal structure. The 3 well-ordered, 30-residue, N-terminal "arms" of each VP7 trimer grip the underlying trimer of VP6, an inner-capsid protein. Structural differences between free and particle-bound VP7 and between free and VP7-coated inner capsids may regulate mRNA transcription and release. The Ca(2+)-stabilized VP7 intratrimer contact region, which presents important neutralizing epitopes, is unaltered upon capsid binding.

-	~~{{STRUCTURE_3gzt\| PDB=3gzt \| SCENE= }}~~	+	Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM.,Chen JZ, Settembre EC, Aoki ST, Zhang X, Bellamy AR, Dormitzer PR, Harrison SC, Grigorieff N Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10644-8. Epub 2009 Jun 1. PMID:19487668<ref>PMID:19487668</ref>

-	~~===VP7 recoated rotavirus DLP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19487668}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3gzt]] is~~ a ~~13 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rhesus_rotavirus Rhesus rotavirus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA].~~	+

	==See Also==		==See Also==
	*[[Virus coat protein\|Virus coat protein]]		*[[Virus coat protein\|Virus coat protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019487668<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Rhesus rotavirus]]		[[Category: Rhesus rotavirus]]
	[[Category: Chen, J Z.]]		[[Category: Chen, J Z.]]

OCA at 21:51, 20 October 2012

OCA — Sat, 20 Oct 2012 21:51:15 GMT

←Older revision		Revision as of 21:51, 20 October 2012
Line 1:		Line 1:
	[[Image:3gzt.png\|left\|200px]]		[[Image:3gzt.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3gzt", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3gzt\| PDB=3gzt \| SCENE= }}		{{STRUCTURE_3gzt\| PDB=3gzt \| SCENE= }}

	===VP7 recoated rotavirus DLP===		===VP7 recoated rotavirus DLP===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19487668}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19487668 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19487668}}		{{ABSTRACT_PUBMED_19487668}}

	==About this Structure==		==About this Structure==
	[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA].		[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA].
		+
		+	==See Also==
		+	*[[Virus coat protein\|Virus coat protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19487668~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019487668</ref><references group="xtra"/>
	[[Category: Rhesus rotavirus]]		[[Category: Rhesus rotavirus]]
	[[Category: Chen, J Z.]]		[[Category: Chen, J Z.]]
Line 28:		Line 20:
	[[Category: Harrison, S C.]]		[[Category: Harrison, S C.]]
	[[Category: Settembre, E C.]]		[[Category: Settembre, E C.]]
		+	[[Category: 7rp]]
		+	[[Category: Capsid protein]]
		+	[[Category: Disulfide bond]]
		+	[[Category: Dlp]]
		+	[[Category: Endoplasmic reticulum]]
		+	[[Category: Glycoprotein]]
		+	[[Category: Icosahedral virus]]
		+	[[Category: Membrane]]
		+	[[Category: Rotavirus]]
		+	[[Category: Transmembrane]]
		+	[[Category: Virion]]
		+	[[Category: Virus]]
		+	[[Category: Vp2]]
		+	[[Category: Vp6]]
		+	[[Category: Vp7]]

OCA: Protected "3gzt" [edit=sysop:move=sysop]

OCA — Wed, 12 Jan 2011 05:23:16 GMT

Protected "3gzt" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:23, 12 January 2011

OCA at 05:23, 12 January 2011

OCA — Wed, 12 Jan 2011 05:23:14 GMT

←Older revision		Revision as of 05:23, 12 January 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3gzt.png\|left\|200px]]
-	[[Image:3gzt.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~3GZT~~ is a 13 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA].	+	[[3gzt]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhesus_rotavirus Rhesus rotavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GZT OCA].

	==Reference==		==Reference==
Line 29:		Line 28:
	[[Category: Harrison, S C.]]		[[Category: Harrison, S C.]]
	[[Category: Settembre, E C.]]		[[Category: Settembre, E C.]]
-	[[Category: 7rp]]
-	[[Category: Capsid protein]]
-	[[Category: Disulfide bond]]
-	[[Category: Dlp]]
-	[[Category: Endoplasmic reticulum]]
-	[[Category: Glycoprotein]]
-	[[Category: Icosahedral virus]]
-	[[Category: Membrane]]
-	[[Category: Rotavirus]]
-	[[Category: Transmembrane]]
-	[[Category: Virion]]
-	[[Category: Vp2]]
-	[[Category: Vp6]]
-	[[Category: Vp7]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 15 08:44:16 2009''