3h3j - Revision history

OCA at 07:15, 6 September 2023

OCA — Wed, 06 Sep 2023 07:15:36 GMT

←Older revision		Revision as of 07:15, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3h3j' size='340' side='right'caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3h3j' size='340' side='right'caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Staac Staac~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H3J FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE~~-~~ADENINE-DINUCLEOTIDE'>NAD</scene>~~, ~~<scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3d0o\|3d0o]], [[3d4p\|3d4p]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">ldh1~~, ~~SACOL0222 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])~~<~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [https://pdbe.org/3h3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [https://www.ebi.ac.uk/pdbsum/3h3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h3j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [https://pdbe.org/3h3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [https://www.ebi.ac.uk/pdbsum/3h3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h3j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC]] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>	+	[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: L-lactate dehydrogenase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staac~~]]	+	[[Category: Staphylococcus aureus subsp. aureus COL]]
-	[[Category: Almo~~, S C~~]]	+	[[Category: Almo SC]]
-	[[Category: Ho, M C]]	+	[[Category: Ho M-C]]
-	[[Category: Schramm~~, V L]]~~	+	[[Category: Schramm VL]]
-	~~[[Category: Alpha-beta motif]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Glycolysis]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Rossmann fold]]~~	+
-	~~[[Category: Stress response~~]]	+

OCA at 11:54, 13 October 2021

OCA — Wed, 13 Oct 2021 11:54:08 GMT

←Older revision		Revision as of 11:54, 13 October 2021
Line 1:		Line 1:

	==Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate==		==Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate==
-	<StructureSection load='3h3j' size='340' side='right' caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3h3j' size='340' side='right'caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3H3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H3J FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d0o\|3d0o]], [[3d4p\|3d4p]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3d0o\|3d0o]], [[3d4p\|3d4p]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [~~http~~://pdbe.org/3h3j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3h3j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3h3j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [https://pdbe.org/3h3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [https://www.ebi.ac.uk/pdbsum/3h3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h3j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC]] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>	+	[[https://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC]] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h3/3h3j_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h3/3h3j_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 22:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h3j ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h3j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Lactate dehydrogenase 3D structures\|Lactate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: L-lactate dehydrogenase]]		[[Category: L-lactate dehydrogenase]]
		+	[[Category: Large Structures]]
	[[Category: Staac]]		[[Category: Staac]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]

OCA at 07:20, 1 November 2017

OCA — Wed, 01 Nov 2017 07:20:17 GMT

←Older revision		Revision as of 07:20, 1 November 2017
Line 22:		Line 22:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h3j ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h3j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-
-	==See Also==
-	*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 32:
	[[Category: Schramm, V L]]		[[Category: Schramm, V L]]
	[[Category: Alpha-beta motif]]		[[Category: Alpha-beta motif]]
		+	[[Category: Cytoplasm]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
	[[Category: Nad]]		[[Category: Nad]]

OCA at 19:35, 4 August 2016

OCA — Thu, 04 Aug 2016 19:35:44 GMT

←Older revision		Revision as of 19:35, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate==		==Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate==
	<StructureSection load='3h3j' size='340' side='right' caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3h3j' size='340' side='right' caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H3J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H3J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d0o\|3d0o]], [[3d4p\|3d4p]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d0o\|3d0o]], [[3d4p\|3d4p]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 ~~Staphylococcus aureus subsp. aureus COL~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [http://www.ebi.ac.uk/pdbsum/3h3j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [http://pdbe.org/3h3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [http://www.ebi.ac.uk/pdbsum/3h3j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3h3j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h3j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 29:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: L-lactate dehydrogenase]]		[[Category: L-lactate dehydrogenase]]
-	[[Category: ~~Staphylococcus aureus subsp. aureus col~~]]	+	[[Category: Staac]]
	[[Category: Almo, S C]]		[[Category: Almo, S C]]
	[[Category: Ho, M C]]		[[Category: Ho, M C]]

OCA at 18:50, 24 December 2014

OCA — Wed, 24 Dec 2014 18:50:40 GMT

←Older revision		Revision as of 18:50, 24 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [http://www.ebi.ac.uk/pdbsum/3h3j PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [http://www.ebi.ac.uk/pdbsum/3h3j PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LDH1_STAAC LDH1_STAAC]] Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells.<ref>PMID:18356528</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 24:
	==See Also==		==See Also==
	*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]		*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:17, 8 December 2014

OCA — Mon, 08 Dec 2014 09:17:33 GMT

←Older revision		Revision as of 09:17, 8 December 2014
Line 1:		Line 1:
-	~~[[Image:3h3j.png\|left\|200px]]~~	+	==Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate==
-		+	<StructureSection load='3h3j' size='340' side='right' caption='[[3h3j]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{STRUCTURE_3h3j\| PDB=3h3j \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3h3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H3J FirstGlance]. <br>
-	===Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate===	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3d0o\|3d0o]], [[3d4p\|3d4p]]</td></tr>
-		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ldh1, SACOL0222 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 Staphylococcus aureus subsp. aureus COL])</td></tr>
-	==~~About this Structure~~==	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
-	[[3h3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h3j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h3j RCSB], [http://www.ebi.ac.uk/pdbsum/3h3j PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h3/3h3j_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]		*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: L-lactate dehydrogenase]]		[[Category: L-lactate dehydrogenase]]
	[[Category: Staphylococcus aureus subsp. aureus col]]		[[Category: Staphylococcus aureus subsp. aureus col]]
-	[[Category: Almo, S C.]]	+	[[Category: Almo, S C]]
-	[[Category: Ho, M C.]]	+	[[Category: Ho, M C]]
-	[[Category: Schramm, V L.]]	+	[[Category: Schramm, V L]]
	[[Category: Alpha-beta motif]]		[[Category: Alpha-beta motif]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]

OCA at 08:07, 20 October 2012

OCA — Sat, 20 Oct 2012 08:07:05 GMT

←Older revision		Revision as of 08:07, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3h3j]] is a 2 chain structure ~~of [[Lactate Dehydrogenase]]~~ with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].	+	[[3h3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].

	==See Also==		==See Also==

OCA: Protected "3h3j" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 18:29:25 GMT

Protected "3h3j" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:29, 25 July 2012

OCA at 18:29, 25 July 2012

OCA — Wed, 25 Jul 2012 18:29:23 GMT

←Older revision		Revision as of 18:29, 25 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3h3j.png\|left\|200px]]
-	[[Image:3h3j.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3h3j", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3h3j\| PDB=3h3j \| SCENE= }}		{{STRUCTURE_3h3j\| PDB=3h3j \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~3H3J~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].	+	[[3h3j]] is a 2 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].
		+
		+	==See Also==
		+	*[[Lactate Dehydrogenase\|Lactate Dehydrogenase]]
	[[Category: L-lactate dehydrogenase]]		[[Category: L-lactate dehydrogenase]]
	[[Category: Staphylococcus aureus subsp. aureus col]]		[[Category: Staphylococcus aureus subsp. aureus col]]
Line 21:		Line 17:
	[[Category: Schramm, V L.]]		[[Category: Schramm, V L.]]
	[[Category: Alpha-beta motif]]		[[Category: Alpha-beta motif]]
-	[[Category: Cytoplasm]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
	[[Category: Nad]]		[[Category: Nad]]
Line 28:		Line 23:
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]
	[[Category: Stress response]]		[[Category: Stress response]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:03:26 2010''

OCA at 08:03, 28 April 2010

OCA — Wed, 28 Apr 2010 08:03:28 GMT

←Older revision		Revision as of 08:03, 28 April 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3h3j.jpg\|left\|200px]]

-	The ~~entry 3h3j~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3h3j", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3h3j\| PDB=3h3j \| SCENE= }}

-	~~Authors: Ho, M.-C., Almo, S.C., Schramm, V.L.~~	+	===Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate===

-	Description: Crystal structure of lactate dehydrogenase mutant (A85R) from staphylococcus aureus complexed with NAD and pyruvate

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 6 09~~:41:~~00 2009~~''	+	==About this Structure==
		+	3H3J is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_col Staphylococcus aureus subsp. aureus col]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3J OCA].
		+	[[Category: L-lactate dehydrogenase]]
		+	[[Category: Staphylococcus aureus subsp. aureus col]]
		+	[[Category: Almo, S C.]]
		+	[[Category: Ho, M C.]]
		+	[[Category: Schramm, V L.]]
		+	[[Category: Alpha-beta motif]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Glycolysis]]
		+	[[Category: Nad]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Phosphoprotein]]
		+	[[Category: Rossmann fold]]
		+	[[Category: Stress response]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:03:26 2010''