3haj - Revision history

OCA at 07:19, 6 September 2023

OCA — Wed, 06 Sep 2023 07:19:10 GMT

←Older revision		Revision as of 07:19, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3haj' size='340' side='right'caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>		<StructureSection load='3haj' size='340' side='right'caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.78Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3hah\|3hah]], [[3hai\|3hai]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">PACSIN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [https://pdbe.org/3haj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [https://www.ebi.ac.uk/pdbsum/3haj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3haj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [https://pdbe.org/3haj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [https://www.ebi.ac.uk/pdbsum/3haj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3haj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PACN2_HUMAN PACN2_HUMAN]] May play a role in endocytosis.	+	[https://www.uniprot.org/uniprot/PACN2_HUMAN PACN2_HUMAN] May play a role in endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Navarro~~, M V.A S~~]]	+	[[Category: Navarro MVAS]]
-	[[Category: Peng, G]]	+	[[Category: Peng G]]
-	[[Category: Rajashankar~~, K R~~]]	+	[[Category: Rajashankar KR]]
-	[[Category: Sondermann, H]]	+	[[Category: Sondermann H]]
-	[[Category: Wang, Q]]	+	[[Category: Wang Q]]
-	~~[[Category: Alternative splicing]]~~	+
-	~~[[Category: Coiled coil]]~~	+
-	~~[[Category: Cytoplasmic vesicle]]~~	+
-	~~[[Category: Endocytosis]]~~	+
-	~~[[Category: F-bar]]~~	+
-	~~[[Category: Fap52]]~~	+
-	~~[[Category: Pacsin]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Polymorphism]]~~	+
-	~~[[Category: Sh3 domain]]~~	+
-	~~[[Category: Syndapin~~]]	+

OCA at 08:07, 16 March 2022

OCA — Wed, 16 Mar 2022 08:07:43 GMT

←Older revision		Revision as of 08:07, 16 March 2022
Line 1:		Line 1:

	==Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)==		==Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)==
-	<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>	+	<StructureSection load='3haj' size='340' side='right'caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hah\|3hah]], [[3hai\|3hai]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [~~http~~://pdbe.org/3haj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3haj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3haj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [https://pdbe.org/3haj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [https://www.ebi.ac.uk/pdbsum/3haj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3haj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PACN2_HUMAN PACN2_HUMAN]] May play a role in endocytosis.	+	[[https://www.uniprot.org/uniprot/PACN2_HUMAN PACN2_HUMAN]] May play a role in endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/3haj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/3haj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Navarro, M V.A S]]		[[Category: Navarro, M V.A S]]
	[[Category: Peng, G]]		[[Category: Peng, G]]

OCA at 07:26, 1 November 2017

OCA — Wed, 01 Nov 2017 07:26:36 GMT

←Older revision		Revision as of 07:26, 1 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)==		==Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)==
	<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>		<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://pdbe.org/3haj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://pdbe.org/3haj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3haj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 39:		Line 40:
	[[Category: Sondermann, H]]		[[Category: Sondermann, H]]
	[[Category: Wang, Q]]		[[Category: Wang, Q]]
		+	[[Category: Alternative splicing]]
		+	[[Category: Coiled coil]]
	[[Category: Cytoplasmic vesicle]]		[[Category: Cytoplasmic vesicle]]
	[[Category: Endocytosis]]		[[Category: Endocytosis]]
Line 45:		Line 48:
	[[Category: Pacsin]]		[[Category: Pacsin]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
		+	[[Category: Polymorphism]]
	[[Category: Sh3 domain]]		[[Category: Sh3 domain]]
	[[Category: Syndapin]]		[[Category: Syndapin]]

OCA at 14:36, 9 February 2016

OCA — Tue, 09 Feb 2016 14:36:22 GMT

←Older revision		Revision as of 14:36, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>		<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://pdbe.org/3haj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3haj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3haj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Navarro, M V.A S]]		[[Category: Navarro, M V.A S]]
	[[Category: Peng, G]]		[[Category: Peng, G]]

OCA at 07:25, 25 December 2014

OCA — Thu, 25 Dec 2014 07:25:48 GMT

←Older revision		Revision as of 07:25, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PACN2_HUMAN PACN2_HUMAN]] May play a role in endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:19, 18 December 2014

OCA — Thu, 18 Dec 2014 06:19:30 GMT

←Older revision		Revision as of 06:19, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3haj\| PDB=3haj \| SCENE= }}~~	+	==Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)==
-	===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===	+	<StructureSection load='3haj' size='340' side='right' caption='[[3haj]], [[Resolution\|resolution]] 2.78Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19549836}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3haj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HAJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hah\|3hah]], [[3hai\|3hai]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PACSIN2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3haj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3haj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3haj RCSB], [http://www.ebi.ac.uk/pdbsum/3haj PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/3haj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Peripheral membrane proteins of the Bin/amphiphysin/Rvs (BAR) and Fer-CIP4 homology-BAR (F-BAR) family participate in cellular membrane trafficking and have been shown to generate membrane tubules. The degree of membrane bending appears to be encoded in the structure and immanent curvature of the particular protein domains, with BAR and F-BAR domains inducing high- and low-curvature tubules, respectively. In addition, oligomerization and the formation of ordered arrays influences tubule stabilization. Here, the F-BAR domain-containing protein Pacsin was found to possess a unique activity, creating small tubules and tubule constrictions, in addition to the wide tubules characteristic for this subfamily. Based on crystal structures of the F-BAR domain of Pacsin and mutagenesis studies, vesiculation could be linked to the presence of unique structural features distinguishing it from other F-BAR proteins. Tubulation was suppressed in the context of the full-length protein, suggesting that Pacsin is autoinhibited in solution. The regulated deformation of membranes and promotion of tubule constrictions by Pacsin suggests a more versatile function of these proteins in vesiculation and endocytosis beyond their role as scaffold proteins.

-	~~==About this Structure==~~	+	Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.,Wang Q, Navarro MV, Peng G, Molinelli E, Lin Goh S, Judson BL, Rajashankar KR, Sondermann H Proc Natl Acad Sci U S A. 2009 Jun 24. PMID:19549836<ref>PMID:19549836</ref>
-	~~[[3haj]] is a 2 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<~~ref group="xtra">PMID:019549836<~~/~~ref~~><~~references group="xtra"~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Navarro, M V.A S.]]	+	[[Category: Navarro, M V.A S]]
-	[[Category: Peng, G.]]	+	[[Category: Peng, G]]
-	[[Category: Rajashankar, K R.]]	+	[[Category: Rajashankar, K R]]
-	[[Category: Sondermann, H.]]	+	[[Category: Sondermann, H]]
-	[[Category: Wang, Q.]]	+	[[Category: Wang, Q]]
	[[Category: Cytoplasmic vesicle]]		[[Category: Cytoplasmic vesicle]]
	[[Category: Endocytosis]]		[[Category: Endocytosis]]

OCA: Protected "3haj" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 10:55:14 GMT

Protected "3haj" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:55, 13 March 2013

OCA at 10:55, 13 March 2013

OCA — Wed, 13 Mar 2013 10:55:11 GMT

←Older revision		Revision as of 10:55, 13 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3haj.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3haj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3haj\| PDB=3haj \| SCENE= }}		{{STRUCTURE_3haj\| PDB=3haj \| SCENE= }}
-
	===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===		===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19549836}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19549836 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19549836}}		{{ABSTRACT_PUBMED_19549836}}

	==About this Structure==		==About this Structure==
-	~~3HAJ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].	+	[[3haj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19549836~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019549836</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Navarro, M V.A S.]]		[[Category: Navarro, M V.A S.]]
Line 30:		Line 14:
	[[Category: Sondermann, H.]]		[[Category: Sondermann, H.]]
	[[Category: Wang, Q.]]		[[Category: Wang, Q.]]
-	[[Category: Alternative splicing]]
-	[[Category: Coiled coil]]
	[[Category: Cytoplasmic vesicle]]		[[Category: Cytoplasmic vesicle]]
	[[Category: Endocytosis]]		[[Category: Endocytosis]]
Line 38:		Line 20:
	[[Category: Pacsin]]		[[Category: Pacsin]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
-	[[Category: Polymorphism]]
	[[Category: Sh3 domain]]		[[Category: Sh3 domain]]
	[[Category: Syndapin]]		[[Category: Syndapin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 21:00:38 2009''

OCA at 18:00, 21 September 2009

OCA — Mon, 21 Sep 2009 18:00:40 GMT

←Older revision		Revision as of 18:00, 21 September 2009
Line 12:		Line 12:
	===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===		===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19549836}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19549836 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19549836}}

	==About this Structure==		==About this Structure==
	3HAJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].		3HAJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19549836</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Navarro, M V.A S.]]		[[Category: Navarro, M V.A S.]]
Line 33:		Line 42:
	[[Category: Syndapin]]		[[Category: Syndapin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 15 20~~:10:46 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 21:00:38 2009''

OCA at 17:05, 15 July 2009

OCA — Wed, 15 Jul 2009 17:05:27 GMT

←Older revision		Revision as of 17:05, 15 July 2009
Line 12:		Line 12:
	===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===		===Crystal structure of human PACSIN2 F-BAR domain (p212121 lattice)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19549836}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19549836 is the PubMed ID number.
-	-->
-	{{ABSTRACT_PUBMED_19549836}}

	==About this Structure==		==About this Structure==
	3HAJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].		3HAJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HAJ OCA].
-
-	==Reference==
-	<ref group="xtra">PMID:19549836</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Navarro, M V.A S.]]		[[Category: Navarro, M V.A S.]]
Line 42:		Line 33:
	[[Category: Syndapin]]		[[Category: Syndapin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 15 08:43:34 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 15 20:10:46 2009''