3hhp - Revision history

OCA at 09:59, 21 February 2024

OCA — Wed, 21 Feb 2024 09:59:58 GMT

←Older revision		Revision as of 09:59, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3hhp' size='340' side='right'caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3hhp' size='340' side='right'caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHP FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>mdh, b3236, JW3205 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id~~=83333 ECOLI])</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	~~<tr id='activity'><td class~~="~~sblockLbl~~">~~<b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>~~[~~https://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~1.~~1.1.37 1.1.1.37] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [https://pdbe.org/3hhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [https://www.ebi.ac.uk/pdbsum/3hhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [https://pdbe.org/3hhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [https://www.ebi.ac.uk/pdbsum/3hhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]	+	[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hhp ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hhp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The structure of apo malate dehydrogenase from Escherichia coli has been determined to 1.45 A resolution. The crystals belonged to space group C2, with unit-cell parameters a = 146.0, b = 52.0, c = 168.9 A, beta = 102.2 degrees. The structure was determined with the molecular-replacement pipeline program BALBES and was refined to a final R factor of 18.6% (R(free) = 21.4%). The final model has two dimers in the asymmetric unit. In each dimer one monomer contains the active-site loop in the open conformation, whereas in the opposing monomer the active-site loop is disordered.
-
-	Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution.,Zaitseva J, Meneely KM, Lamb AL Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt, 9):866-9. Epub 2009 Aug 20. PMID:19724119<ref>PMID:19724119</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3hhp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Malate Dehydrogenase 3D structures\|Malate Dehydrogenase 3D structures]]		*[[Malate Dehydrogenase 3D structures\|Malate Dehydrogenase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Malate dehydrogenase]]~~	+	[[Category: Lamb AL]]
-	[[Category: Lamb~~, A L~~]]	+	[[Category: Meneely KM]]
-	[[Category: Meneely~~, K M~~]]	+	[[Category: Zaitseva J]]
-	[[Category: Zaitseva, J]]	+
-	~~[[Category: Citric acid cycle]]~~	+
-	~~[[Category: Mdh]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Tca cycle]]~~	+
-	~~[[Category: Tricarboxylic acid cycle~~]]	+

OCA at 12:48, 23 March 2022

OCA — Wed, 23 Mar 2022 12:48:07 GMT

←Older revision		Revision as of 12:48, 23 March 2022
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	==Malate dehydrogenase open conformation==		==Malate dehydrogenase open conformation==
-	<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='3hhp' size='340' side='right'caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HHP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHP FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [~~http~~://pdbe.org/3hhp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hhp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [https://pdbe.org/3hhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [https://www.ebi.ac.uk/pdbsum/3hhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]	+	[[https://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Malate ~~dehydrogenase~~\|Malate ~~dehydrogenase~~]]	+	*[[Malate Dehydrogenase 3D structures\|Malate Dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Malate dehydrogenase]]		[[Category: Malate dehydrogenase]]
	[[Category: Lamb, A L]]		[[Category: Lamb, A L]]

OCA at 08:16, 12 December 2018

OCA — Wed, 12 Dec 2018 08:16:55 GMT

←Older revision		Revision as of 08:16, 12 December 2018
Line 1:		Line 1:
		+
	==Malate dehydrogenase open conformation==		==Malate dehydrogenase open conformation==
	<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://pdbe.org/3hhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://pdbe.org/3hhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hhp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hhp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:58, 10 February 2016

OCA — Wed, 10 Feb 2016 06:58:17 GMT

←Older revision		Revision as of 06:58, 10 February 2016
Line 2:		Line 2:
	<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HHP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HHP FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ~~Escherichia coli K-12~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://pdbe.org/3hhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hhp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hhp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Malate dehydrogenase]]		[[Category: Malate dehydrogenase]]
	[[Category: Lamb, A L]]		[[Category: Lamb, A L]]

OCA at 12:35, 25 December 2014

OCA — Thu, 25 Dec 2014 12:35:19 GMT

←Older revision		Revision as of 12:35, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MDH_ECOLI MDH_ECOLI]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01516]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:27, 21 December 2014

OCA — Sun, 21 Dec 2014 17:27:28 GMT

←Older revision		Revision as of 17:27, 21 December 2014
Line 1:		Line 1:
-	[[~~Image~~:3hhp.~~png\|left~~\|200px]]	+	==Malate dehydrogenase open conformation==
		+	<StructureSection load='3hhp' size='340' side='right' caption='[[3hhp]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hhp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HHP FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mdh, b3236, JW3205 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hhp RCSB], [http://www.ebi.ac.uk/pdbsum/3hhp PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/3hhp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of apo malate dehydrogenase from Escherichia coli has been determined to 1.45 A resolution. The crystals belonged to space group C2, with unit-cell parameters a = 146.0, b = 52.0, c = 168.9 A, beta = 102.2 degrees. The structure was determined with the molecular-replacement pipeline program BALBES and was refined to a final R factor of 18.6% (R(free) = 21.4%). The final model has two dimers in the asymmetric unit. In each dimer one monomer contains the active-site loop in the open conformation, whereas in the opposing monomer the active-site loop is disordered.

-	~~{{STRUCTURE_3hhp\| PDB=3hhp \| SCENE= }}~~	+	Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution.,Zaitseva J, Meneely KM, Lamb AL Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt, 9):866-9. Epub 2009 Aug 20. PMID:19724119<ref>PMID:19724119</ref>

-	~~===Malate dehydrogenase open conformation===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19724119}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3hhp]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].~~	+

	==See Also==		==See Also==
-	*[[Johnson sandbox 1\|Johnson sandbox 1]]
	*[[Malate dehydrogenase\|Malate dehydrogenase]]		*[[Malate dehydrogenase\|Malate dehydrogenase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019724119<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Malate dehydrogenase]]		[[Category: Malate dehydrogenase]]
-	[[Category: Lamb, A L.]]	+	[[Category: Lamb, A L]]
-	[[Category: Meneely, K M.]]	+	[[Category: Meneely, K M]]
-	[[Category: Zaitseva, J.]]	+	[[Category: Zaitseva, J]]
	[[Category: Citric acid cycle]]		[[Category: Citric acid cycle]]
-	[[Category: Malate dehydrogenase]]
	[[Category: Mdh]]		[[Category: Mdh]]
	[[Category: Nad]]		[[Category: Nad]]

OCA at 16:44, 20 October 2012

OCA — Sat, 20 Oct 2012 16:44:14 GMT

←Older revision		Revision as of 16:44, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3hhp]] is a 4 chain structure ~~of [[Johnson sandbox 1]] and [[Malate dehydrogenase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].	+	[[3hhp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].

	==See Also==		==See Also==

OCA at 22:40, 26 July 2012

OCA — Thu, 26 Jul 2012 22:40:20 GMT

←Older revision		Revision as of 22:40, 26 July 2012
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	[[Image:3hhp.png\|left\|200px]]		[[Image:3hhp.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hhp", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hhp\| PDB=3hhp \| SCENE= }}		{{STRUCTURE_3hhp\| PDB=3hhp \| SCENE= }}

	===Malate dehydrogenase open conformation===		===Malate dehydrogenase open conformation===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19724119}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19724119 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19724119}}		{{ABSTRACT_PUBMED_19724119}}

	==About this Structure==		==About this Structure==
-	[[3hhp]] is a 4 chain structure of [[Malate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].	+	[[3hhp]] is a 4 chain structure of [[Johnson sandbox 1]] and [[Malate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].

	==See Also==		==See Also==
-	*[[Malate dehydrogenase]]	+	*[[Johnson sandbox 1\|Johnson sandbox 1]]
		+	*[[Malate dehydrogenase\|Malate dehydrogenase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19724119~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019724119</ref><references group="xtra"/>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Malate dehydrogenase]]		[[Category: Malate dehydrogenase]]

OCA: Protected "3hhp" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 22:02:30 GMT

Protected "3hhp" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:02, 26 December 2010

OCA at 22:02, 26 December 2010

OCA — Sun, 26 Dec 2010 22:02:28 GMT

←Older revision		Revision as of 22:02, 26 December 2010
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3hhp.png\|left\|200px]]
-	[[Image:3hhp.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~3HHP~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].	+	[[3hhp]] is a 4 chain structure of [[Malate dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHP OCA].
		+
		+	==See Also==
		+	*[[Malate dehydrogenase]]

	==Reference==		==Reference==
Line 36:		Line 38:
	[[Category: Tca cycle]]		[[Category: Tca cycle]]
	[[Category: Tricarboxylic acid cycle]]		[[Category: Tricarboxylic acid cycle]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:43:47 2009''