3hmg - Revision history

OCA at 10:49, 16 September 2020

OCA — Wed, 16 Sep 2020 10:49:34 GMT

←Older revision		Revision as of 10:49, 16 September 2020
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	==REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING==		==REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING==
-	<StructureSection load='3hmg' size='340' side='right' caption='[[3hmg]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='3hmg' size='340' side='right'caption='[[3hmg]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/I68a0 I68a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HMG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/I68a0 I68a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3HMG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://pdbe.org/3hmg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://pdbe.org/3hmg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Hemagglutinin\|Hemagglutinin]]	+	*[[Hemagglutinin 3D structures\|Hemagglutinin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: I68a0]]		[[Category: I68a0]]
		+	[[Category: Large Structures]]
	[[Category: Bruenger, A T]]		[[Category: Bruenger, A T]]
	[[Category: Skehel, J J]]		[[Category: Skehel, J J]]

OCA at 07:33, 12 December 2018

OCA — Wed, 12 Dec 2018 07:33:45 GMT

←Older revision		Revision as of 07:33, 12 December 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hmg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hmg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:32, 5 August 2016

OCA — Fri, 05 Aug 2016 02:32:24 GMT

←Older revision		Revision as of 02:32, 5 August 2016
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		+
	==REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING==		==REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING==
	<StructureSection load='3hmg' size='340' side='right' caption='[[3hmg]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3hmg' size='340' side='right' caption='[[3hmg]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Influenza_a_virus Influenza a virus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HMG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/I68a0 I68a0]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HMG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://pdbe.org/3hmg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hmg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~HEMA_IAAIC HEMA_IAAIC~~]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.	+	[[http://www.uniprot.org/uniprot/HEMA_I68A0 HEMA_I68A0]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hmg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hmg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Influenza a virus~~]]	+	[[Category: I68a0]]
	[[Category: Bruenger, A T]]		[[Category: Bruenger, A T]]
	[[Category: Skehel, J J]]		[[Category: Skehel, J J]]

OCA at 15:08, 25 December 2014

OCA — Thu, 25 Dec 2014 15:08:41 GMT

←Older revision		Revision as of 15:08, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HEMA_IAAIC HEMA_IAAIC]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 05:57, 18 December 2014

OCA — Thu, 18 Dec 2014 05:57:14 GMT

←Older revision		Revision as of 05:57, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3hmg\| PDB=3hmg \| SCENE= }}~~	+	==REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING==
-	===REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING===	+	<StructureSection load='3hmg' size='340' side='right' caption='[[3hmg]], [[Resolution\|resolution]] 2.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_2329580}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HMG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hmg RCSB], [http://www.ebi.ac.uk/pdbsum/3hmg PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hm/3hmg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have applied the method of simulated annealing to the refinement of the 3 A resolution crystal structure of the influenza virus hemagglutinin glycoprotein, using the program X-PLOR. Two different methods were introduced into X-PLOR to treat the non-crystallographic symmetry present in this and in other crystal structures. In the first, only the unique protomer atoms are refined; by application of the non-crystallographic symmetry operators to the protomer atoms, the X-ray structure factor derivatives are effectively averaged, and a non-bonded energy term models the interactions of the protomer with its neighbors in the oligomer without explicit refinement of the other protomers in the crystallographic asymmetric unit. In the second method, the entire asymmetric unit is refined, but an effective energy term is added to the empirical energy that restrains symmetry-related atomic positions to their average values after least-squares superposition. Several other modifications and additions were made to previously published X-PLOR protocols, including weighting of the X-ray terms, maintenance of the temperature of the molecular dynamics simulation, treatment of charged groups, changes in the values of certain empirical energy parameters, and the use of N-linked carbohydrate empirical energy parameters. The hemagglutinin refinement proceeded in several stages. An initial round of simulated annealing of the monomer was followed by rigid-body refinement of the 3-fold non-crystallographic symmetry axis position and a second round of monomer refinement. A third round was performed on the trimer using non-crystallographic symmetry restraints in all regions except those in lattice contacts showing obvious derivations from 3-fold symmetry. The refinement was completed with several rounds of conventional positional and isotropic temperature factor refinement needed to correct bad model geometry introduced by high-temperature molecular dynamics in regions of weak electron density. This structure was then used as the basis for refinement of three crystallographically isomorphous hemagglutinin structures, including complexes with the influenza virus receptor, sialic acid. Model geometry comparable to well-refined high-resolution structures was obtained with relatively little manual intervention, demonstrating the ability of simulated annealing refinement to produce highly idealized structures at moderate resolution.

-	~~==About this Structure==~~	+	Refinement of the influenza virus hemagglutinin by simulated annealing.,Weis WI, Brunger AT, Skehel JJ, Wiley DC J Mol Biol. 1990 Apr 20;212(4):737-61. PMID:2329580<ref>PMID:2329580</ref>
-	~~[[3hmg]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Influenza_a_virus Influenza a virus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3HMG OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Hemagglutinin\|Hemagglutinin]]		*[[Hemagglutinin\|Hemagglutinin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:002329580<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Influenza a virus]]		[[Category: Influenza a virus]]
-	[[Category: Bruenger, A T.]]	+	[[Category: Bruenger, A T]]
-	[[Category: Skehel, J J.]]	+	[[Category: Skehel, J J]]
-	[[Category: Weis, W I.]]	+	[[Category: Weis, W I]]
-	[[Category: Wiley, D C.]]	+	[[Category: Wiley, D C]]
	[[Category: Influenza virus hemagglutinin]]		[[Category: Influenza virus hemagglutinin]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 09:06, 11 March 2013

OCA — Mon, 11 Mar 2013 09:06:12 GMT

←Older revision		Revision as of 09:06, 11 March 2013
Line 1:		Line 1:
-	[[Image:3hmg.png\|left\|200px]]
-
	{{STRUCTURE_3hmg\| PDB=3hmg \| SCENE= }}		{{STRUCTURE_3hmg\| PDB=3hmg \| SCENE= }}
-
	===REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING===		===REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING===
-
	{{ABSTRACT_PUBMED_2329580}}		{{ABSTRACT_PUBMED_2329580}}

OCA at 18:09, 20 October 2012

OCA — Sat, 20 Oct 2012 18:09:22 GMT

←Older revision		Revision as of 18:09, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3hmg]] is a 6 chain structure ~~of [[Hemagglutinin]]~~ with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].	+	[[3hmg]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].

	==See Also==		==See Also==

OCA: Protected "3hmg" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 03:11:43 GMT

Protected "3hmg" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:11, 27 July 2012

OCA at 03:11, 27 July 2012

OCA — Fri, 27 Jul 2012 03:11:40 GMT

←Older revision		Revision as of 03:11, 27 July 2012
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-	{{Seed}}
	[[Image:3hmg.png\|left\|200px]]		[[Image:3hmg.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hmg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hmg\| PDB=3hmg \| SCENE= }}		{{STRUCTURE_3hmg\| PDB=3hmg \| SCENE= }}

	===REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING===		===REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_2329580}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 2329580 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_2329580}}		{{ABSTRACT_PUBMED_2329580}}

	==About this Structure==		==About this Structure==
-	~~3HMG~~ is a 6 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/~~Unidentified_influenza_virus Unidentified influenza~~ virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].	+	[[3hmg]] is a 6 chain structure of [[Hemagglutinin]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].
		+
		+	==See Also==
		+	*[[Hemagglutinin\|Hemagglutinin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~2329580~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:002329580</ref><references group="xtra"/>
-	[[Category: ~~Unidentified influenza~~ virus]]	+	[[Category: Influenza a virus]]
	[[Category: Bruenger, A T.]]		[[Category: Bruenger, A T.]]
	[[Category: Skehel, J J.]]		[[Category: Skehel, J J.]]
Line 30:		Line 21:
	[[Category: Wiley, D C.]]		[[Category: Wiley, D C.]]
	[[Category: Influenza virus hemagglutinin]]		[[Category: Influenza virus hemagglutinin]]
-		+	[[Category: Viral protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 19:48:40 2009''~~	+

OCA at 17:48, 17 February 2009

OCA — Tue, 17 Feb 2009 17:48:42 GMT

←Older revision		Revision as of 17:48, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	3HMG is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Unidentified_influenza_virus Unidentified influenza virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].	+	3HMG is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Unidentified_influenza_virus Unidentified influenza virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HMG OCA].

	==Reference==		==Reference==
-	~~Refinement of the influenza virus hemagglutinin by simulated annealing., Weis WI, Brunger AT, Skehel JJ, Wiley DC, J Mol Biol. 1990 Apr 20;212(4):737-61.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/2329580 2329580]~~	+	<ref group="xtra">PMID:2329580</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Unidentified influenza virus]]		[[Category: Unidentified influenza virus]]
	[[Category: Bruenger, A T.]]		[[Category: Bruenger, A T.]]
Line 32:		Line 31:
	[[Category: Influenza virus hemagglutinin]]		[[Category: Influenza virus hemagglutinin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jul 3 12~~:49:~~29 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:48:40 2009''