3hos - Revision history

OCA at 15:52, 1 November 2023

OCA — Wed, 01 Nov 2023 15:52:01 GMT

←Older revision		Revision as of 15:52, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3hos' size='340' side='right'caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='3hos' size='340' side='right'caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Droma Droma~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOS FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3hot\|3hot]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">T ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 DROMA])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [https://pdbe.org/3hos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [https://www.ebi.ac.uk/pdbsum/3hos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hos ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [https://pdbe.org/3hos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [https://www.ebi.ac.uk/pdbsum/3hos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hos ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.	+	[https://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Droma~~]]	+	[[Category: Drosophila mauritiana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Richardson~~, J M~~]]	+	[[Category: Richardson JM]]
-	[[Category: Walkinshaw~~, M D]]~~	+	[[Category: Walkinshaw MD]]
-	~~[[Category: Dna binding protein-dna complex]]~~	+
-	~~[[Category: Inverted repeat dna]]~~	+
-	~~[[Category: Protein-dna complex]]~~	+
-	~~[[Category: Synaptic complex]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transposase~~]]	+

OCA at 07:44, 10 November 2021

OCA — Wed, 10 Nov 2021 07:44:51 GMT

←Older revision		Revision as of 07:44, 10 November 2021
Line 1:		Line 1:

	==Crystal structure of the mariner Mos1 paired end complex with Mg==		==Crystal structure of the mariner Mos1 paired end complex with Mg==
-	<StructureSection load='3hos' size='340' side='right' caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<StructureSection load='3hos' size='340' side='right'caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Droma Droma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Droma Droma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HOS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hot\|3hot]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hot\|3hot]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">T ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 DROMA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">T ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 DROMA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [~~http~~://pdbe.org/3hos PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hos PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hos ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [https://pdbe.org/3hos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [https://www.ebi.ac.uk/pdbsum/3hos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hos ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.	+	[[https://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Transposase\|Transposase]]	+	*[[Transposase 3D structures\|Transposase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Droma]]		[[Category: Droma]]
		+	[[Category: Large Structures]]
	[[Category: Richardson, J M]]		[[Category: Richardson, J M]]
	[[Category: Walkinshaw, M D]]		[[Category: Walkinshaw, M D]]

OCA at 07:52, 12 December 2018

OCA — Wed, 12 Dec 2018 07:52:31 GMT

←Older revision		Revision as of 07:52, 12 December 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hos_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hos_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:21, 5 August 2016

OCA — Fri, 05 Aug 2016 17:21:04 GMT

←Older revision		Revision as of 17:21, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the mariner Mos1 paired end complex with Mg==		==Crystal structure of the mariner Mos1 paired end complex with Mg==
	<StructureSection load='3hos' size='340' side='right' caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='3hos' size='340' side='right' caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_mauritiana Drosophila mauritiana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Droma Droma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hot\|3hot]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hot\|3hot]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">T ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 ~~Drosophila mauritiana~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">T ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 DROMA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [http://www.ebi.ac.uk/pdbsum/3hos PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [http://pdbe.org/3hos PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [http://www.ebi.ac.uk/pdbsum/3hos PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hos ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hos ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hos" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drosophila mauritiana~~]]	+	[[Category: Droma]]
	[[Category: Richardson, J M]]		[[Category: Richardson, J M]]
	[[Category: Walkinshaw, M D]]		[[Category: Walkinshaw, M D]]

OCA at 20:36, 25 December 2014

OCA — Thu, 25 Dec 2014 20:36:01 GMT

←Older revision		Revision as of 20:36, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [http://www.ebi.ac.uk/pdbsum/3hos PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [http://www.ebi.ac.uk/pdbsum/3hos PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:35, 18 December 2014

OCA — Thu, 18 Dec 2014 17:35:35 GMT

←Older revision		Revision as of 17:35, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3hos\| PDB=3hos \| SCENE= }}~~	+	==Crystal structure of the mariner Mos1 paired end complex with Mg==
-	===Crystal structure of the mariner Mos1 paired end complex with Mg===	+	<StructureSection load='3hos' size='340' side='right' caption='[[3hos]], [[Resolution\|resolution]] 3.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19766564}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hos]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HOS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hot\|3hot]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">T ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7226 Drosophila mauritiana])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hos OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hos RCSB], [http://www.ebi.ac.uk/pdbsum/3hos PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ho/3hos_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A key step in cut-and-paste DNA transposition is the pairing of transposon ends before the element is excised and inserted at a new site in its host genome. Crystallographic analyses of the paired-end complex (PEC) formed from precleaved transposon ends and the transposase of the eukaryotic element Mos1 reveals two parallel ends bound to a dimeric enzyme. The complex has a trans arrangement, with each transposon end recognized by the DNA binding region of one transposase monomer and by the active site of the other monomer. Two additional DNA duplexes in the crystal indicate likely binding sites for flanking DNA. Biochemical data provide support for a model of the target capture complex and identify Arg186 to be critical for target binding. Mixing experiments indicate that a transposase dimer initiates first-strand cleavage and suggest a pathway for PEC formation.

-	~~==Function==~~	+	Molecular architecture of the Mos1 paired-end complex: the structural basis of DNA transposition in a eukaryote.,Richardson JM, Colloms SD, Finnegan DJ, Walkinshaw MD Cell. 2009 Sep 18;138(6):1096-108. PMID:19766564<ref>PMID:19766564</ref>
-	~~[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition~~ of ~~transposon~~ Mos1 ~~by a 'cut and paste' mechanism. Transposases are sequence~~-~~specific nucleases and strand transferases that catalyze transposition through an ordered series of events~~: ~~sequence-specific binding of transposase to~~ the ~~terminal inverted repeats (IR) present at each end~~ of ~~the transposon, pairing of the transposon IRs~~ in a ~~paired-end complex (PEC)~~, ~~cleavage of one or both DNA strands at each transposon end~~, ~~capture of target DNA~~, ~~and strand transfer to insert the transposon at a new site~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3hos]] is~~ a ~~8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Drosophila_mauritiana Drosophila mauritiana]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:019766564</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Transposase\|Transposase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Drosophila mauritiana]]		[[Category: Drosophila mauritiana]]
-	[[Category: Richardson, J M.]]	+	[[Category: Richardson, J M]]
-	[[Category: Walkinshaw, M D.]]	+	[[Category: Walkinshaw, M D]]
	[[Category: Dna binding protein-dna complex]]		[[Category: Dna binding protein-dna complex]]
	[[Category: Inverted repeat dna]]		[[Category: Inverted repeat dna]]

OCA at 06:50, 16 October 2013

OCA — Wed, 16 Oct 2013 06:50:54 GMT

←Older revision		Revision as of 06:50, 16 October 2013
Line 1:		Line 1:
-	[[Image:3hos.png\|left\|200px]]
-
	{{STRUCTURE_3hos\| PDB=3hos \| SCENE= }}		{{STRUCTURE_3hos\| PDB=3hos \| SCENE= }}
-
	===Crystal structure of the mariner Mos1 paired end complex with Mg===		===Crystal structure of the mariner Mos1 paired end complex with Mg===
		+	{{ABSTRACT_PUBMED_19766564}}

-	~~{{ABSTRACT_PUBMED_19766564}}~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site.

	==About this Structure==		==About this Structure==
Line 11:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019766564</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019766564</ref><references group="xtra"/><references/>
	[[Category: Drosophila mauritiana]]		[[Category: Drosophila mauritiana]]
	[[Category: Richardson, J M.]]		[[Category: Richardson, J M.]]

OCA: Protected "3hos" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2013 14:57:26 GMT

Protected "3hos" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:57, 6 March 2013

OCA at 14:57, 6 March 2013

OCA — Wed, 06 Mar 2013 14:57:24 GMT

←Older revision		Revision as of 14:57, 6 March 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3hos.png\|left\|200px]]		[[Image:3hos.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hos", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hos\| PDB=3hos \| SCENE= }}		{{STRUCTURE_3hos\| PDB=3hos \| SCENE= }}

	===Crystal structure of the mariner Mos1 paired end complex with Mg===		===Crystal structure of the mariner Mos1 paired end complex with Mg===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19766564}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19766564 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19766564}}		{{ABSTRACT_PUBMED_19766564}}

	==About this Structure==		==About this Structure==
-	~~3HOS~~ is a 8 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA].	+	[[3hos]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19766564~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019766564</ref><references group="xtra"/>
	[[Category: Drosophila mauritiana]]		[[Category: Drosophila mauritiana]]
	[[Category: Richardson, J M.]]		[[Category: Richardson, J M.]]
	[[Category: Walkinshaw, M D.]]		[[Category: Walkinshaw, M D.]]
-	[[Category: Dna binding protein/dna complex]]	+	[[Category: Dna binding protein-dna complex]]
	[[Category: Inverted repeat dna]]		[[Category: Inverted repeat dna]]
	[[Category: Protein-dna complex]]		[[Category: Protein-dna complex]]
Line 33:		Line 21:
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Transposase]]		[[Category: Transposase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:28:44 2009''

OCA at 11:28, 7 October 2009

OCA — Wed, 07 Oct 2009 11:28:44 GMT

←Older revision		Revision as of 11:28, 7 October 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3hos.~~jpg~~\|left\|200px]]	+	[[Image:3hos.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal structure of the mariner Mos1 paired end complex with Mg===		===Crystal structure of the mariner Mos1 paired end complex with Mg===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19766564}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19766564 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19766564}}

	==About this Structure==		==About this Structure==
	3HOS is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA].		3HOS is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_mauritiana Drosophila mauritiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOS OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19766564</ref><references group="xtra"/>
	[[Category: Drosophila mauritiana]]		[[Category: Drosophila mauritiana]]
	[[Category: Richardson, J M.]]		[[Category: Richardson, J M.]]
Line 25:		Line 34:
	[[Category: Transposase]]		[[Category: Transposase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 23 08~~:58:15 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:28:44 2009''