3hx0 - Revision history

OCA at 07:33, 6 September 2023

OCA — Wed, 06 Sep 2023 07:33:06 GMT

←Older revision		Revision as of 07:33, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3hx0' size='340' side='right'caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3hx0' size='340' side='right'caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=D3T:2~~,3~~-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3hw8\|3hw8]], [[3hwt\|3hwt]]~~</~~div~~><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">POLL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [https://pdbe.org/3hx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [https://www.ebi.ac.uk/pdbsum/3hx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hx0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [https://pdbe.org/3hx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [https://www.ebi.ac.uk/pdbsum/3hx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hx0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>	+	[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hx0 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hx0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bebenek, K]]	+	[[Category: Bebenek K]]
-	[[Category: Garcia-Diaz, M]]	+	[[Category: Garcia-Diaz M]]
-	[[Category: Havener~~, J M~~]]	+	[[Category: Havener JM]]
-	[[Category: Krahn~~, J M~~]]	+	[[Category: Krahn JM]]
-	[[Category: Kunkel~~, T A~~]]	+	[[Category: Kunkel TA]]
-	[[Category: Larrea~~, A A~~]]	+	[[Category: Larrea AA]]
-	[[Category: Pedersen~~, L C~~]]	+	[[Category: Pedersen LC]]
-	[[Category: Perera, L]]	+	[[Category: Perera L]]
-	[[Category: Ramsden~~, D A]]~~	+	[[Category: Ramsden DA]]
-	~~[[Category: Dna damage]]~~	+
-	~~[[Category: Dna repair]]~~	+
-	~~[[Category: Dna replication]]~~	+
-	~~[[Category: Dna synthesis]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Dna-directed dna polymerase]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Manganese]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Nucleotidyltransferase]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Polymerase lambda]]~~	+
-	~~[[Category: Polymorphism]]~~	+
-	~~[[Category: Scrunch]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-dna complex]]~~	+
-	~~[[Category: X-family~~]]	+

OCA at 12:05, 13 October 2021

OCA — Wed, 13 Oct 2021 12:05:11 GMT

←Older revision		Revision as of 12:05, 13 October 2021
Line 1:		Line 1:

	==ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA==		==ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA==
-	<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='3hx0' size='340' side='right'caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hw8\|3hw8]], [[3hwt\|3hwt]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [~~http~~://pdbe.org/3hx0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hx0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hx0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [https://pdbe.org/3hx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [https://www.ebi.ac.uk/pdbsum/3hx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hx0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>	+	[[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 21:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hx0 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hx0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Bebenek, K]]		[[Category: Bebenek, K]]
	[[Category: Garcia-Diaz, M]]		[[Category: Garcia-Diaz, M]]

OCA at 08:14, 12 December 2018

OCA — Wed, 12 Dec 2018 08:14:24 GMT

←Older revision		Revision as of 08:14, 12 December 2018
Line 1:		Line 1:
		+
	==ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA==		==ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA==
	<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://pdbe.org/3hx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://pdbe.org/3hx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hx0 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hx0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hx0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 50:		Line 51:
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Polymerase lambda]]		[[Category: Polymerase lambda]]
		+	[[Category: Polymorphism]]
	[[Category: Scrunch]]		[[Category: Scrunch]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Transferase-dna complex]]		[[Category: Transferase-dna complex]]
	[[Category: X-family]]		[[Category: X-family]]

OCA at 01:40, 9 February 2016

OCA — Tue, 09 Feb 2016 01:40:42 GMT

←Older revision		Revision as of 01:40, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://pdbe.org/3hx0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hx0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Bebenek, K]]		[[Category: Bebenek, K]]
	[[Category: Garcia-Diaz, M]]		[[Category: Garcia-Diaz, M]]

OCA at 03:33, 25 December 2014

OCA — Thu, 25 Dec 2014 03:33:13 GMT

←Older revision		Revision as of 03:33, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN]] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 23:
	==See Also==		==See Also==
	*[[DNA polymerase\|DNA polymerase]]		*[[DNA polymerase\|DNA polymerase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Bebenek, K.]]	+	[[Category: Bebenek, K]]
-	[[Category: Garcia-Diaz, M.]]	+	[[Category: Garcia-Diaz, M]]
-	[[Category: Havener, J M.]]	+	[[Category: Havener, J M]]
-	[[Category: Krahn, J M.]]	+	[[Category: Krahn, J M]]
-	[[Category: Kunkel, T A.]]	+	[[Category: Kunkel, T A]]
-	[[Category: Larrea, A A.]]	+	[[Category: Larrea, A A]]
-	[[Category: Pedersen, L C.]]	+	[[Category: Pedersen, L C]]
-	[[Category: Perera, L.]]	+	[[Category: Perera, L]]
-	[[Category: Ramsden, D A.]]	+	[[Category: Ramsden, D A]]
	[[Category: Dna damage]]		[[Category: Dna damage]]
	[[Category: Dna repair]]		[[Category: Dna repair]]

OCA at 13:27, 29 September 2014

OCA — Mon, 29 Sep 2014 13:27:23 GMT

←Older revision		Revision as of 13:27, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:3hx0.png\|left\|200px]]~~	+	==ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA==
-		+	<StructureSection load='3hx0' size='340' side='right' caption='[[3hx0]], [[Resolution\|resolution]] 3.00Å' scene=''>
-	~~{{STRUCTURE_3hx0\| PDB=3hx0 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HX0 FirstGlance]. <br>
-	===ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D3T:2,3-DIDEOXY-THYMIDINE-5-TRIPHOSPHATE'>D3T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hw8\|3hw8]], [[3hwt\|3hwt]]</td></tr>
-	~~{{ABSTRACT_PUBMED_019701199}}~~	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">POLL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hx0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hx0 RCSB], [http://www.ebi.ac.uk/pdbsum/3hx0 PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	<table>
-	[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].	+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hx0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[DNA polymerase\|DNA polymerase]]		*[[DNA polymerase\|DNA polymerase]]
-		+	__TOC__
-	~~==Reference==~~	+	</StructureSection>
-	~~<ref group="xtra">PMID:019701199</ref>~~<~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bebenek, K.]]		[[Category: Bebenek, K.]]

OCA at 12:12, 20 October 2012

OCA — Sat, 20 Oct 2012 12:12:11 GMT

←Older revision		Revision as of 12:12, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3hx0]] is a 16 chain structure ~~of [[DNA polymerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].	+	[[3hx0]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].

	==See Also==		==See Also==

OCA: Protected "3hx0" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 07:56:40 GMT

Protected "3hx0" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:56, 26 July 2012

OCA at 07:56, 26 July 2012

OCA — Thu, 26 Jul 2012 07:56:38 GMT

←Older revision		Revision as of 07:56, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3hx0.png\|left\|200px]]		[[Image:3hx0.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hx0", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hx0\| PDB=3hx0 \| SCENE= }}		{{STRUCTURE_3hx0\| PDB=3hx0 \| SCENE= }}

	===ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA===		===ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA===

		+	{{ABSTRACT_PUBMED_019701199}}

	==About this Structure==		==About this Structure==
-	~~3HX0~~ is a 16 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].	+	[[3hx0]] is a 16 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].
		+
		+	==See Also==
		+	*[[DNA polymerase\|DNA polymerase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:019701199</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bebenek, K.]]		[[Category: Bebenek, K.]]
Line 38:		Line 38:
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Polymerase lambda]]		[[Category: Polymerase lambda]]
-	[[Category: Polymorphism]]
	[[Category: Scrunch]]		[[Category: Scrunch]]
	[[Category: Transferase]]		[[Category: Transferase]]
-	[[Category: Transferase/dna complex]]	+	[[Category: Transferase-dna complex]]
	[[Category: X-family]]		[[Category: X-family]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:05:48 2009''

OCA at 14:05, 21 September 2009

OCA — Mon, 21 Sep 2009 14:05:49 GMT

←Older revision		Revision as of 14:05, 21 September 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3hx0.png\|left\|200px]]

-	The ~~entry 3hx0~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3hx0", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3hx0\| PDB=3hx0 \| SCENE= }}

-	~~Authors: Garcia-Diaz~~, M., ~~Bebenek, K., Larrea, A.A., Havener, J.M., Perera, L., Krahn, J.M., Pedersen, L.C., Ramsden, D.A., Kunkel, T.A.~~	+	===ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA===

-	Description: ternary complex of L277A, H511A, R514 mutant pol lambda bound to a 2 nucleotide gapped DNA substrate with a scrunched dA

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 5 09~~:46:07 2009''	+	==About this Structure==
		+	3HX0 is a 16 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX0 OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Bebenek, K.]]
		+	[[Category: Garcia-Diaz, M.]]
		+	[[Category: Havener, J M.]]
		+	[[Category: Krahn, J M.]]
		+	[[Category: Kunkel, T A.]]
		+	[[Category: Larrea, A A.]]
		+	[[Category: Pedersen, L C.]]
		+	[[Category: Perera, L.]]
		+	[[Category: Ramsden, D A.]]
		+	[[Category: Dna damage]]
		+	[[Category: Dna repair]]
		+	[[Category: Dna replication]]
		+	[[Category: Dna synthesis]]
		+	[[Category: Dna-binding]]
		+	[[Category: Dna-directed dna polymerase]]
		+	[[Category: Lyase]]
		+	[[Category: Manganese]]
		+	[[Category: Metal-binding]]
		+	[[Category: Nucleotidyltransferase]]
		+	[[Category: Nucleus]]
		+	[[Category: Phosphoprotein]]
		+	[[Category: Polymerase lambda]]
		+	[[Category: Polymorphism]]
		+	[[Category: Scrunch]]
		+	[[Category: Transferase]]
		+	[[Category: Transferase/dna complex]]
		+	[[Category: X-family]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:05:48 2009''