3hzl - Revision history

OCA at 07:34, 6 September 2023

OCA — Wed, 06 Sep 2023 07:34:14 GMT

←Older revision		Revision as of 07:34, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3hzl' size='340' side='right'caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3hzl' size='340' side='right'caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_4.1460 As 4.1460~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2olo\|2olo]], [[2oln\|2oln]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 AS 4.1460])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [https://pdbe.org/3hzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [https://www.ebi.ac.uk/pdbsum/3hzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [https://pdbe.org/3hzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [https://www.ebi.ac.uk/pdbsum/3hzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzl ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9X9P9_STRTE Q9X9P9_STRTE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: As 4 1460]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Carrell, C J~~]]	+	[[Category: Streptomyces tendae]]
-	[[Category: ~~Jorns, M S~~]]	+	[[Category: Carrell CJ]]
-	[[Category: ~~Mathews, F S~~]]	+	[[Category: Jorns MS]]
-	[[Category: ~~Flavoprotein]]~~	+	[[Category: Mathews FS]]
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 12:06, 13 October 2021

OCA — Wed, 13 Oct 2021 12:06:14 GMT

←Older revision		Revision as of 12:06, 13 October 2021
Line 1:		Line 1:

	==Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution==		==Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution==
-	<StructureSection load='3hzl' size='340' side='right' caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='3hzl' size='340' side='right'caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_4.1460 As 4.1460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HZL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1460 As 4.1460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2olo\|2olo]], [[2oln\|2oln]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2olo\|2olo]], [[2oln\|2oln]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 AS 4.1460])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 AS 4.1460])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [~~http~~://pdbe.org/3hzl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hzl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [https://pdbe.org/3hzl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [https://www.ebi.ac.uk/pdbsum/3hzl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzl ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: As 4 1460]]		[[Category: As 4 1460]]
		+	[[Category: Large Structures]]
	[[Category: Carrell, C J]]		[[Category: Carrell, C J]]
	[[Category: Jorns, M S]]		[[Category: Jorns, M S]]

OCA at 07:42, 12 December 2018

OCA — Wed, 12 Dec 2018 07:42:20 GMT

←Older revision		Revision as of 07:42, 12 December 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzl_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzl_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:03, 5 August 2016

OCA — Fri, 05 Aug 2016 17:03:08 GMT

←Older revision		Revision as of 17:03, 5 August 2016
Line 1:		Line 1:
		+
	==Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution==		==Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution==
	<StructureSection load='3hzl' size='340' side='right' caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3hzl' size='340' side='right' caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_tendae Streptomyces tendae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1460 As 4.1460]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2olo\|2olo]], [[2oln\|2oln]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2olo\|2olo]], [[2oln\|2oln]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 ~~Streptomyces tendae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 AS 4.1460])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [http://www.ebi.ac.uk/pdbsum/3hzl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [http://pdbe.org/3hzl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [http://www.ebi.ac.uk/pdbsum/3hzl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzl ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hzl ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hzl" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces tendae~~]]	+	[[Category: As 4 1460]]
	[[Category: Carrell, C J]]		[[Category: Carrell, C J]]
	[[Category: Jorns, M S]]		[[Category: Jorns, M S]]

OCA at 06:13, 18 December 2014

OCA — Thu, 18 Dec 2014 06:13:16 GMT

←Older revision		Revision as of 06:13, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3hzl\| PDB=3hzl \| SCENE= }}~~	+	==Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution==
-	===Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution===	+	<StructureSection load='3hzl' size='340' side='right' caption='[[3hzl]], [[Resolution\|resolution]] 1.55Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19702312}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hzl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZL FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PC:PYRIDINE-2-CARBOXYLIC+ACID'>6PC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2olo\|2olo]], [[2oln\|2oln]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nikD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1932 Streptomyces tendae])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzl RCSB], [http://www.ebi.ac.uk/pdbsum/3hzl PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzl_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	NikD is a flavoprotein oxidase that catalyzes the oxidation of piperideine-2-carboxylate (P2C) to picolinate in a remarkable aromatization reaction comprising two redox cycles and at least one isomerization step. Tyr258 forms part of an "aromatic cage" that surrounds the ring in picolinate and its precursors. Mutation of Tyr258 to Phe does not perturb the structure of nikD but does affect the coupling of the two redox cycles and causes a 10-fold decrease in turnover rate. Tyr258Phe catalyzes a quantitative two-electron oxidation of P2C, but only 60% of the resulting dihydropicolinate intermediate undergoes a second redox cycle to produce picolinate. The mutation does not affect product yield with an alternate substrate (3,4-dehydro-L-proline) that is aromatized in a single two-electron oxidation step. Wild-type and mutant enzymes exhibit identical rate constants for oxidation of P2C to dihydropicolinate and isomerization of a reduced enzyme.dihydropicolinate complex. The observed rates are 200- and 10-fold faster, respectively, than the mutant turnover rate. Release of picolinate from Tyr258Phe is 100-fold faster than turnover. The presence of a bound substrate or product is a key factor in oxygen activation by wild-type nikD, as judged by the 10-75-fold faster rates observed for complexes of the reduced enzyme with picolinate, benzoate, or 1-cyclohexenoate, a 1-deaza-P2C analogue. The reduced Tyr258Phe x 1-cyclohexenoate complex is 25-fold less reactive with oxygen than the wild-type complex. We postulate that mutation of Tyr258 causes subtle changes in active site dynamics that promote release of the reactive dihydropicolinate intermediate and disrupt the efficient synchronization of oxygen activation observed with wild-type nikD.

-	~~==About this Structure==~~	+	Factors that affect oxygen activation and coupling of the two redox cycles in the aromatization reaction catalyzed by NikD, an unusual amino acid oxidase.,Kommoju PR, Bruckner RC, Ferreira P, Carrell CJ, Mathews FS, Jorns MS Biochemistry. 2009 Oct 13;48(40):9542-55. PMID:19702312<ref>PMID:19702312</ref>
-	~~[[3hzl]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_tendae Streptomyces tendae]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<~~ref group="xtra">PMID:019702312<~~/~~ref~~><~~references group="xtra"~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces tendae]]		[[Category: Streptomyces tendae]]
-	[[Category: Carrell, C J.]]	+	[[Category: Carrell, C J]]
-	[[Category: Jorns, M S.]]	+	[[Category: Jorns, M S]]
-	[[Category: Mathews, F S.]]	+	[[Category: Mathews, F S]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]

OCA: Protected "3hzl" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 10:48:59 GMT

Protected "3hzl" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:48, 13 March 2013

OCA at 10:48, 13 March 2013

OCA — Wed, 13 Mar 2013 10:48:56 GMT

←Older revision		Revision as of 10:48, 13 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3hzl.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hzl", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hzl\| PDB=3hzl \| SCENE= }}		{{STRUCTURE_3hzl\| PDB=3hzl \| SCENE= }}
-
	===Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution===		===Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19702312}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19702312 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19702312}}		{{ABSTRACT_PUBMED_19702312}}

	==About this Structure==		==About this Structure==
-	~~3HZL~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA].	+	[[3hzl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19702312~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019702312</ref><references group="xtra"/>
	[[Category: Streptomyces tendae]]		[[Category: Streptomyces tendae]]
	[[Category: Carrell, C J.]]		[[Category: Carrell, C J.]]
Line 31:		Line 15:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:19:29 2009''

OCA at 08:19, 21 October 2009

OCA — Wed, 21 Oct 2009 08:19:31 GMT

←Older revision		Revision as of 08:19, 21 October 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3hzl.jpg\|left\|200px]]

-	The ~~entry 3hzl~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3hzl", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3hzl\| PDB=3hzl \| SCENE= }}

-	~~Authors~~: ~~Mathews, F.S., Jorns, M.S., Carrell, C.J~~.	+	===Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution===

-	Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 22 20~~:33:47 2009''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19702312}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19702312 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19702312}}
		+
		+	==About this Structure==
		+	3HZL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_tendae Streptomyces tendae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZL OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19702312</ref><references group="xtra"/>
		+	[[Category: Streptomyces tendae]]
		+	[[Category: Carrell, C J.]]
		+	[[Category: Jorns, M S.]]
		+	[[Category: Mathews, F S.]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Rossmann fold]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:19:29 2009''

OCA at 17:33, 22 July 2009

OCA — Wed, 22 Jul 2009 17:33:47 GMT

←Older revision		Revision as of 17:33, 22 July 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3hzl is ON HOLD	+	The entry 3hzl is ON HOLD until Paper Publication

	Authors: Mathews, F.S., Jorns, M.S., Carrell, C.J.		Authors: Mathews, F.S., Jorns, M.S., Carrell, C.J.
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	Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution		Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul ~~1 08~~:57:55 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:33:47 2009''

OCA: New page: '''Unreleased structure''' The entry 3hzl is ON HOLD Authors: Mathews, F.S., Jorns, M.S., Carrell, C.J. Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential f...

OCA — Wed, 01 Jul 2009 05:57:55 GMT

New page: '''Unreleased structure''' The entry 3hzl is ON HOLD Authors: Mathews, F.S., Jorns, M.S., Carrell, C.J. Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential f...

New page

'''Unreleased structure'''

The entry 3hzl is ON HOLD

Authors: Mathews, F.S., Jorns, M.S., Carrell, C.J.

Description: Tyr258Phe mutant of NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.55A resolution

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 08:57:55 2009''