3hzv - Revision history

OCA at 07:34, 6 September 2023

OCA — Wed, 06 Sep 2023 07:34:25 GMT

←Older revision		Revision as of 07:34, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3hzv' size='340' side='right'caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3hzv' size='340' side='right'caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3HZV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~"><~~scene name='pdbligand=MG:MAGNESIUM+ION'~~>MG</~~scene~~>, <~~scene name~~='~~pdbligand~~=ZN:~~ZINC+ION'~~>ZN</~~scene~~>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene><~~/td~~></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<~~tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td>~~<td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [~~http~~://pdbe.org/3hzv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hzv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [https://pdbe.org/3hzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [https://www.ebi.ac.uk/pdbsum/3hzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 37:		Line 37:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Borisova~~, S N~~]]	+	[[Category: Borisova SN]]
-	[[Category: Brade, H]]	+	[[Category: Brade H]]
-	[[Category: Brade, L]]	+	[[Category: Brade L]]
-	[[Category: Brooks~~, C L~~]]	+	[[Category: Brooks CL]]
-	[[Category: Evans~~, S V~~]]	+	[[Category: Evans SV]]
-	[[Category: Hirama, T]]	+	[[Category: Hirama T]]
-	[[Category: Kosma, P]]	+	[[Category: Kosma P]]
-	[[Category: MacKenzie~~, C R~~]]	+	[[Category: MacKenzie CR]]
-	[[Category: Muller-Loennies, S]]	+	[[Category: Muller-Loennies S]]
-	~~[[Category: Antibody]]~~	+
-	~~[[Category: Carbohydrate]]~~	+
-	~~[[Category: Fab]]~~	+
-	~~[[Category: Igg]]~~	+
-	~~[[Category: Immune system~~]]	+

OCA at 10:52, 16 September 2020

OCA — Wed, 16 Sep 2020 10:52:46 GMT

←Older revision		Revision as of 10:52, 16 September 2020
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	==Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo==		==Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo==
-	<StructureSection load='3hzv' size='340' side='right' caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3hzv' size='340' side='right'caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HZV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3HZV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO~~</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://pdbe.org/3hzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://pdbe.org/3hzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	==See Also==		==See Also==
	*[[Antibody 3D structures\|Antibody 3D structures]]		*[[Antibody 3D structures\|Antibody 3D structures]]
		+	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Borisova, S N]]		[[Category: Borisova, S N]]

OCA at 08:07, 12 December 2018

OCA — Wed, 12 Dec 2018 08:07:05 GMT

←Older revision		Revision as of 08:07, 12 December 2018
Line 1:		Line 1:
		+
	==Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo==		==Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo==
	<StructureSection load='3hzv' size='340' side='right' caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3hzv' size='340' side='right' caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZV FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>,~~ <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://pdbe.org/3hzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://pdbe.org/3hzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzv ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzv_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzv_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:

	==See Also==		==See Also==
-	*[[Antibody\|Antibody]]	+	*[[Antibody 3D structures\|Antibody 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 03:07, 9 February 2016

OCA — Tue, 09 Feb 2016 03:07:17 GMT

←Older revision		Revision as of 03:07, 9 February 2016
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://pdbe.org/3hzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hzv ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3hzv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 10:38, 20 January 2015

OCA — Tue, 20 Jan 2015 10:38:15 GMT

←Older revision		Revision as of 10:38, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZV FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZV FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Borisova, S N.]]	+	[[Category: Borisova, S N]]
-	[[Category: Brade, H.]]	+	[[Category: Brade, H]]
-	[[Category: Brade, L.]]	+	[[Category: Brade, L]]
-	[[Category: Brooks, C L.]]	+	[[Category: Brooks, C L]]
-	[[Category: Evans, S V.]]	+	[[Category: Evans, S V]]
-	[[Category: Hirama, T.]]	+	[[Category: Hirama, T]]
-	[[Category: Kosma, P.]]	+	[[Category: Kosma, P]]
-	[[Category: MacKenzie, C R.]]	+	[[Category: MacKenzie, C R]]
-	[[Category: Muller-Loennies, S.]]	+	[[Category: Muller-Loennies, S]]
	[[Category: Antibody]]		[[Category: Antibody]]
	[[Category: Carbohydrate]]		[[Category: Carbohydrate]]

OCA at 12:31, 29 September 2014

OCA — Mon, 29 Sep 2014 12:31:12 GMT

←Older revision		Revision as of 12:31, 29 September 2014
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-	[[~~Image:~~3hzv.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo==
		+	<StructureSection load='3hzv' size='340' side='right' caption='[[3hzv]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HZV FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=KDA:(3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID)-2-O-ALLYL'>KDA</scene>, <scene name='pdbligand=KDO:3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KDO</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3hzk\|3hzk]], [[3hzm\|3hzm]], [[3hzy\|3hzy]], [[3i02\|3i02]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hzv RCSB], [http://www.ebi.ac.uk/pdbsum/3hzv PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzv_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structures of antigen-binding fragments from two related monoclonal antibodies have been determined to high resolution in the presence of several carbohydrate antigens raised against chlamydial lipopolysaccharide. With the exception of CDR H3, antibodies S54-10 and S73-2 are both derived from the same set of germline gene segments as the previously reported structures S25-2 and S45-18. Despite this similarity, the antibodies differ in specificity and the mechanism by which they recognize their cognate antigen. S54-10 uses an unrelated CDR H3 to recognize its antigen in a fashion analogous to S45-18; however, S73-2 recognizes the same antigen as S45-18 and S54-10 in a wholly unrelated manner. Together, these antibody-antigen structures provide snapshots into how the immune system uses the same set of inherited germline gene segments to generate multiple possible specificities that allow for differential recognition of epitopes and how unrelated CDR H3 sequences can result in convergent binding of clinically relevant bacterial antigens.

-	~~{{STRUCTURE_3hzv\| PDB=3hzv \| SCENE= }}~~	+	Antibodies Raised Against Chlamydial Lipopolysaccharide Antigens Reveal Convergence in Germline Gene Usage and Differential Epitope Recognition.,Brooks CL, Muller-Loennies S, Borisova SN, Brade L, Kosma P, Hirama T, Mackenzie CR, Brade H, Evans SV Biochemistry. 2009 Dec 31. PMID:20000757<ref>PMID:20000757</ref>

-	~~===Crystal structure~~ of ~~S73-2 antibody in complex with antigen Kdo(2~~.~~8)Kdo(2~~.~~4)Kdo===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20000757}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3hzv]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].~~	+

	==See Also==		==See Also==
	*[[Antibody\|Antibody]]		*[[Antibody\|Antibody]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020000757<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Borisova, S N.]]		[[Category: Borisova, S N.]]

OCA at 12:26, 20 October 2012

OCA — Sat, 20 Oct 2012 12:26:01 GMT

←Older revision		Revision as of 12:26, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[3hzv]] is a 2 chain structure ~~of [[Antibody]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].	+	[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].

	==See Also==		==See Also==

OCA at 08:42, 26 July 2012

OCA — Thu, 26 Jul 2012 08:42:04 GMT

←Older revision		Revision as of 08:42, 26 July 2012
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	[[Image:3hzv.png\|left\|200px]]		[[Image:3hzv.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3hzv", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3hzv\| PDB=3hzv \| SCENE= }}		{{STRUCTURE_3hzv\| PDB=3hzv \| SCENE= }}

	===Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo===		===Crystal structure of S73-2 antibody in complex with antigen Kdo(2.8)Kdo(2.4)Kdo===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20000757}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20000757 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20000757}}		{{ABSTRACT_PUBMED_20000757}}

	==About this Structure==		==About this Structure==
-	[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].	+	[[3hzv]] is a 2 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].
		+
		+	==See Also==
		+	*[[Antibody\|Antibody]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20000757~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020000757</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Borisova, S N.]]		[[Category: Borisova, S N.]]
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	[[Category: MacKenzie, C R.]]		[[Category: MacKenzie, C R.]]
	[[Category: Muller-Loennies, S.]]		[[Category: Muller-Loennies, S.]]
		+	[[Category: Antibody]]
		+	[[Category: Carbohydrate]]
		+	[[Category: Fab]]
		+	[[Category: Igg]]
		+	[[Category: Immune system]]

OCA: Protected "3hzv" [edit=sysop:move=sysop]

OCA — Wed, 16 Mar 2011 07:25:39 GMT

Protected "3hzv" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:25, 16 March 2011

OCA at 07:25, 16 March 2011

OCA — Wed, 16 Mar 2011 07:25:38 GMT

←Older revision		Revision as of 07:25, 16 March 2011
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-	{{Seed}}
	[[Image:3hzv.png\|left\|200px]]		[[Image:3hzv.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3HZV~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].	+	[[3hzv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZV OCA].

	==Reference==		==Reference==
Line 34:		Line 33:
	[[Category: MacKenzie, C R.]]		[[Category: MacKenzie, C R.]]
	[[Category: Muller-Loennies, S.]]		[[Category: Muller-Loennies, S.]]
-	[[Category: Antibody]]
-	[[Category: Carbohydrate]]
-	[[Category: Fab]]
-	[[Category: Igg]]
-	[[Category: Immune system]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:02:55 2010''