3i5g - Revision history

OCA at 07:37, 6 September 2023

OCA — Wed, 06 Sep 2023 07:37:51 GMT

←Older revision		Revision as of 07:37, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3i5g' size='340' side='right'caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3i5g' size='340' side='right'caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Loligo_pealei Loligo pealei~~] and [~~http~~://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3I5G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [https://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~, ~~<scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[2oy6\|2oy6]]~~, ~~[[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [~~http~~://pdbe.org/3i5g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3i5g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [https://pdbe.org/3i5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [https://www.ebi.ac.uk/pdbsum/3i5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~MLE_TODPA MLE_TODPA~~]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_TODPA MLR_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.	+	[https://www.uniprot.org/uniprot/O44934_DORPE O44934_DORPE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Doryteuthis pealeii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Loligo pealei]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
-	[[Category: Brown~~, J H~~]]	+	[[Category: Brown JH]]
-	[[Category: Cohen, C]]	+	[[Category: Cohen C]]
-	[[Category: Gourinath, S]]	+	[[Category: Gourinath S]]
-	[[Category: Himmel~~, D M~~]]	+	[[Category: Himmel DM]]
-	[[Category: Kovacs, M]]	+	[[Category: Kovacs M]]
-	[[Category: ~~Neall-Hennessey, E O~~]]	+	[[Category: Nyitray L]]
-	[[Category: ~~Nyitray, L~~]]	+	[[Category: O'Neall-Hennessey E]]
-	[[Category: Reshetnikova, L]]	+	[[Category: Reshetnikova L]]
-	[[Category: Reutzel, R]]	+	[[Category: Reutzel R]]
-	[[Category: Szent-Gyorgyi~~, A G~~]]	+	[[Category: Szent-Gyorgyi AG]]
-	[[Category: Yang, Y]]	+	[[Category: Yang Y]]
-	~~[[Category: Contractile protein]]~~	+
-	~~[[Category: Muscle myosin]]~~	+
-	~~[[Category: Rigor-like]]~~	+
-	~~[[Category: Squid~~]]	+

OCA at 11:52, 23 September 2020

OCA — Wed, 23 Sep 2020 11:52:52 GMT

←Older revision		Revision as of 11:52, 23 September 2020
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	==Crystal structure of rigor-like squid myosin S1==		==Crystal structure of rigor-like squid myosin S1==
-	<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='3i5g' size='340' side='right'caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3I5G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://pdbe.org/3i5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://pdbe.org/3i5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Myosin\|Myosin]]	+	*[[Myosin 3D Structures\|Myosin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Loligo pealei]]		[[Category: Loligo pealei]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]

OCA at 10:11, 19 December 2018

OCA — Wed, 19 Dec 2018 10:11:53 GMT

←Older revision		Revision as of 10:11, 19 December 2018
Line 1:		Line 1:
		+
	==Crystal structure of rigor-like squid myosin S1==		==Crystal structure of rigor-like squid myosin S1==
	<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://pdbe.org/3i5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://pdbe.org/3i5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i5g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5g_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5g_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:17, 9 February 2016

OCA — Tue, 09 Feb 2016 05:17:43 GMT

←Older revision		Revision as of 05:17, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Doryteuthis_pealeii Doryteuthis pealeii~~] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://pdbe.org/3i5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i5g ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3i5g" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Doryteuthis pealeii~~]]	+	[[Category: Loligo pealei]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
	[[Category: Brown, J H]]		[[Category: Brown, J H]]

OCA at 04:41, 25 December 2014

OCA — Thu, 25 Dec 2014 04:41:59 GMT

←Older revision		Revision as of 04:41, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>		<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MLE_TODPA MLE_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity. [[http://www.uniprot.org/uniprot/MLR_TODPA MLR_TODPA]] In molluscan muscle, calcium regulation is associated with myosin rather than with actin. Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	[[Category: Doryteuthis pealeii]]		[[Category: Doryteuthis pealeii]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
-	[[Category: Brown, J H.]]	+	[[Category: Brown, J H]]
-	[[Category: Cohen, C.]]	+	[[Category: Cohen, C]]
-	[[Category: Gourinath, S.]]	+	[[Category: Gourinath, S]]
-	[[Category: Himmel, D M.]]	+	[[Category: Himmel, D M]]
-	[[Category: Kovacs, M.]]	+	[[Category: Kovacs, M]]
-	[[Category: Neall-Hennessey, E O.]]	+	[[Category: Neall-Hennessey, E O]]
-	[[Category: Nyitray, L.]]	+	[[Category: Nyitray, L]]
-	[[Category: Reshetnikova, L.]]	+	[[Category: Reshetnikova, L]]
-	[[Category: Reutzel, R.]]	+	[[Category: Reutzel, R]]
-	[[Category: Szent-Gyorgyi, A G.]]	+	[[Category: Szent-Gyorgyi, A G]]
-	[[Category: Yang, Y.]]	+	[[Category: Yang, Y]]
	[[Category: Contractile protein]]		[[Category: Contractile protein]]
	[[Category: Muscle myosin]]		[[Category: Muscle myosin]]
	[[Category: Rigor-like]]		[[Category: Rigor-like]]
	[[Category: Squid]]		[[Category: Squid]]

OCA at 13:37, 29 September 2014

OCA — Mon, 29 Sep 2014 13:37:57 GMT

←Older revision		Revision as of 13:37, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3i5g.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of rigor-like squid myosin S1==
		+	<StructureSection load='3i5g' size='340' side='right' caption='[[3i5g]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I5G FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2oy6\|2oy6]], [[3i5f\|3i5f]], [[3i5h\|3i5h]], [[3i5i\|3i5i]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i5g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i5g RCSB], [http://www.ebi.ac.uk/pdbsum/3i5g PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i5g_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Unlike processive cellular motors such as myosin V, whose structure has recently been determined in a "rigor-like" conformation, myosin II from contracting muscle filaments necessarily spends most of its time detached from actin. By using squid and sea scallop sources, however, we have now obtained similar rigor-like atomic structures for muscle myosin heads (S1). The significance of the hallmark closed actin-binding cleft in these crystal structures is supported here by actin/S1-binding studies. These structures reveal how different duty ratios, and hence cellular functions, of the myosin isoforms may be accounted for, in part, on the basis of detailed differences in interdomain contacts. Moreover, the rigor-like position of switch II turns out to be unique for myosin V. The overall arrangements of subdomains in the motor are relatively conserved in each of the known contractile states, and we explore qualitatively the energetics of these states.

-	~~{{STRUCTURE_3i5g\| PDB=3i5g \| SCENE= }}~~	+	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.,Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C Structure. 2007 May;15(5):553-64. PMID:17502101<ref>PMID:17502101</ref>

-	~~===Crystal structure~~ of ~~rigor-like squid myosin S1===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17502101}}~~	+
-		+
-	~~==About this Structure==~~	+
-	[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA].~~	+

	==See Also==		==See Also==
	*[[Myosin\|Myosin]]		*[[Myosin\|Myosin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017502101<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Doryteuthis pealeii]]		[[Category: Doryteuthis pealeii]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]

OCA at 12:46, 20 October 2012

OCA — Sat, 20 Oct 2012 12:46:12 GMT

←Older revision		Revision as of 12:46, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3i5g]] is a 3 chain structure ~~of [[Myosin]]~~ with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA].	+	[[3i5g]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA].

	==See Also==		==See Also==

OCA at 09:49, 26 July 2012

OCA — Thu, 26 Jul 2012 09:49:30 GMT

←Older revision		Revision as of 09:49, 26 July 2012
Line 1:		Line 1:
	[[Image:3i5g.png\|left\|200px]]		[[Image:3i5g.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3i5g", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3i5g\| PDB=3i5g \| SCENE= }}		{{STRUCTURE_3i5g\| PDB=3i5g \| SCENE= }}

	===Crystal structure of rigor-like squid myosin S1===		===Crystal structure of rigor-like squid myosin S1===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17502101}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17502101 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17502101}}		{{ABSTRACT_PUBMED_17502101}}

	==About this Structure==		==About this Structure==
-	[[3i5g]] is a 3 chain structure of [[Myosin]] with sequence from [http://en.wikipedia.org/wiki/~~Loligo_pealei Loligo pealei~~] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA].	+	[[3i5g]] is a 3 chain structure of [[Myosin]] with sequence from [http://en.wikipedia.org/wiki/Doryteuthis_pealeii Doryteuthis pealeii] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ovk 2ovk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5G OCA].

	==See Also==		==See Also==
-	*[[Myosin]]	+	*[[Myosin\|Myosin]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:017502101</ref><references group="xtra"/>		<ref group="xtra">PMID:017502101</ref><references group="xtra"/>
-	[[Category: ~~Loligo pealei~~]]	+	[[Category: Doryteuthis pealeii]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
	[[Category: Brown, J H.]]		[[Category: Brown, J H.]]

OCA at 11:45, 26 May 2011

OCA — Thu, 26 May 2011 11:45:18 GMT

←Older revision		Revision as of 11:45, 26 May 2011
Line 25:		Line 25:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17502101~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017502101</ref><references group="xtra"/>
	[[Category: Loligo pealei]]		[[Category: Loligo pealei]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]

OCA: Protected "3i5g" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 23:25:32 GMT

Protected "3i5g" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:25, 26 December 2010