3iau - Revision history

OCA at 03:27, 21 April 2022

OCA — Thu, 21 Apr 2022 03:27:53 GMT

←Older revision		Revision as of 03:27, 21 April 2022
Line 1:		Line 1:

	==The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum==		==The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum==
-	<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='3iau' size='340' side='right'caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iau]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lycopersicon_esculentum Lycopersicon esculentum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IAU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iau]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lycopersicon_esculentum Lycopersicon esculentum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IAU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Lycopersicon esculentum])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Lycopersicon esculentum])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [~~http~~://pdbe.org/3iau PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3iau PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3iau ProSAT], [~~http~~://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [https://pdbe.org/3iau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [https://www.ebi.ac.uk/pdbsum/3iau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iau ProSAT], [https://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/3iau_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/3iau_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 3iau" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3iau" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Deaminase 3D structures\|Deaminase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lycopersicon esculentum]]		[[Category: Lycopersicon esculentum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]

OCA at 08:01, 1 November 2017

OCA — Wed, 01 Nov 2017 08:01:42 GMT

←Older revision		Revision as of 08:01, 1 November 2017
Line 1:		Line 1:
		+
	==The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum==		==The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum==
	<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Lycopersicon esculentum])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Lycopersicon esculentum])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [http://pdbe.org/3iau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [http://www.ebi.ac.uk/pdbsum/3iau PDBsum], [http://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [http://pdbe.org/3iau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [http://www.ebi.ac.uk/pdbsum/3iau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iau ProSAT], [http://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 3iau" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3iau" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Deaminase\|Deaminase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:11, 9 February 2016

OCA — Tue, 09 Feb 2016 21:11:43 GMT

←Older revision		Revision as of 21:11, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Solanum_lycopersicum Solanum lycopersicum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IAU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lycopersicon_esculentum Lycopersicon esculentum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IAU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:2-~~LYSINE(~~3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-~~YLMETHANE)~~'>LLP</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 ~~Solanum lycopersicum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Lycopersicon esculentum])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [http://www.ebi.ac.uk/pdbsum/3iau PDBsum], [http://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [http://pdbe.org/3iau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [http://www.ebi.ac.uk/pdbsum/3iau PDBsum], [http://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iau ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3iau" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Solanum lycopersicum~~]]	+	[[Category: Lycopersicon esculentum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]
	[[Category: Bianchetti, C M]]		[[Category: Bianchetti, C M]]

OCA at 15:33, 18 December 2014

OCA — Thu, 18 Dec 2014 15:33:53 GMT

←Older revision		Revision as of 15:33, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3iau\| PDB=3iau \| SCENE= }}~~	+	==The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum==
-	===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===	+	<StructureSection load='3iau' size='340' side='right' caption='[[3iau]], [[Resolution\|resolution]] 2.35Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21436043}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IAU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4081 Solanum lycopersicum])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_ammonia-lyase Threonine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.19 4.3.1.19] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iau RCSB], [http://www.ebi.ac.uk/pdbsum/3iau PDBsum], [http://www.topsan.org/Proteins/CESG/3iau TOPSAN]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/3iau_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Gene duplication is a major source of plant chemical diversity that mediates plant-herbivore interactions. There is little direct evidence, however, that novel chemical traits arising from gene duplication reduce herbivory. Higher plants use threonine deaminase (TD) to catalyze the dehydration of threonine (Thr) to alpha-ketobutyrate and ammonia as the committed step in the biosynthesis of isoleucine (Ile). Cultivated tomato and related Solanum species contain a duplicated TD paralog (TD2) that is coexpressed with a suite of genes involved in herbivore resistance. Analysis of TD2-deficient tomato lines showed that TD2 has a defensive function related to Thr catabolism in the gut of lepidopteran herbivores. During herbivory, the regulatory domain of TD2 is removed by proteolysis to generate a truncated protein (pTD2) that efficiently degrades Thr without being inhibited by Ile. We show that this proteolytic activation step occurs in the gut of lepidopteran but not coleopteran herbivores, and is catalyzed by a chymotrypsin-like protease of insect origin. Analysis of purified recombinant enzymes showed that TD2 is remarkably more resistant to proteolysis and high temperature than the ancestral TD1 isoform. The crystal structure of pTD2 provided evidence that electrostatic interactions constitute a stabilizing feature associated with adaptation of TD2 to the extreme environment of the lepidopteran gut. These findings demonstrate a role for gene duplication in the evolution of a plant defense that targets and co-opts herbivore digestive physiology.

-	~~==About this Structure==~~	+	Adaptive evolution of threonine deaminase in plant defense against insect herbivores.,Gonzales-Vigil E, Bianchetti CM, Phillips GN Jr, Howe GA Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5897-902. Epub 2011 Mar 21. PMID:21436043<ref>PMID:21436043</ref>
-	~~[[3iau]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3IAU OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:021436043</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[Deaminase\|Deaminase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Solanum lycopersicum]]		[[Category: Solanum lycopersicum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]
-	[[Category: Bianchetti, C M.]]	+	[[Category: Bianchetti, C M]]
-	[[Category: Bingman, C A.]]	+	[[Category: Bingman, C A]]
-	[[Category: ~~CESG, Center for Eukaryotic~~ Structural ~~Genomics.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Phillips, G N.]]	+	[[Category: Phillips, G N]]
	[[Category: Allosteric enzyme]]		[[Category: Allosteric enzyme]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]
	[[Category: Branched-chain amino acid biosynthesis]]		[[Category: Branched-chain amino acid biosynthesis]]
-	[[Category: Center for eukaryotic structural genomic]]
	[[Category: Cesg]]		[[Category: Cesg]]
	[[Category: Chloroplast]]		[[Category: Chloroplast]]
Line 25:		Line 50:
	[[Category: Jasmonic acid pathway]]		[[Category: Jasmonic acid pathway]]
	[[Category: Lyase]]		[[Category: Lyase]]
-	[[Category: Protein structure initiative]]	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category: Psi~~]]	+
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]
-	[[Category: Structural genomic]]
	[[Category: Transit peptide]]		[[Category: Transit peptide]]

OCA at 09:34, 27 March 2013

OCA — Wed, 27 Mar 2013 09:34:19 GMT

←Older revision		Revision as of 09:34, 27 March 2013
Line 1:		Line 1:
-	[[Image:3iau.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3iau", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3iau\| PDB=3iau \| SCENE= }}		{{STRUCTURE_3iau\| PDB=3iau \| SCENE= }}
-
	===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===		===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21436043}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21436043 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21436043}}		{{ABSTRACT_PUBMED_21436043}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:021436043</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021436043</ref><references group="xtra"/><references/>
	[[Category: Solanum lycopersicum]]		[[Category: Solanum lycopersicum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]
Line 29:		Line 14:
	[[Category: CESG, Center for Eukaryotic Structural Genomics.]]		[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
	[[Category: Phillips, G N.]]		[[Category: Phillips, G N.]]
		+	[[Category: Allosteric enzyme]]
		+	[[Category: Amino-acid biosynthesis]]
		+	[[Category: Branched-chain amino acid biosynthesis]]
		+	[[Category: Center for eukaryotic structural genomic]]
		+	[[Category: Cesg]]
		+	[[Category: Chloroplast]]
		+	[[Category: Defensive protein]]
		+	[[Category: Isoleucine biosynthesis]]
		+	[[Category: Jasmonic acid]]
		+	[[Category: Jasmonic acid pathway]]
		+	[[Category: Lyase]]
		+	[[Category: Protein structure initiative]]
		+	[[Category: Psi]]
		+	[[Category: Pyridoxal phosphate]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transit peptide]]

OCA at 11:29, 26 May 2011

OCA — Thu, 26 May 2011 11:29:02 GMT

←Older revision		Revision as of 11:29, 26 May 2011
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21436043~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021436043</ref><references group="xtra"/>
	[[Category: Solanum lycopersicum]]		[[Category: Solanum lycopersicum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]

OCA at 09:52, 21 April 2011

OCA — Thu, 21 Apr 2011 09:52:26 GMT

←Older revision		Revision as of 09:52, 21 April 2011
Line 11:		Line 11:
	===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===		===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21436043}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21436043 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21436043}}

	==About this Structure==		==About this Structure==
	[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA].		[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21436043</ref><references group="xtra"/>
	[[Category: Solanum lycopersicum]]		[[Category: Solanum lycopersicum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]

OCA: Protected "3iau" [edit=sysop:move=sysop]

OCA — Wed, 23 Mar 2011 06:18:54 GMT

Protected "3iau" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:18, 23 March 2011

OCA at 06:18, 23 March 2011

OCA — Wed, 23 Mar 2011 06:18:52 GMT

←Older revision		Revision as of 06:18, 23 March 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3iau.png\|left\|200px]]		[[Image:3iau.png\|left\|200px]]

Line 14:		Line 13:

	==About this Structure==		==About this Structure==
-	~~3IAU~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA].	+	[[3iau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA].
	[[Category: Solanum lycopersicum]]		[[Category: Solanum lycopersicum]]
	[[Category: Threonine ammonia-lyase]]		[[Category: Threonine ammonia-lyase]]
Line 21:		Line 20:
	[[Category: CESG, Center for Eukaryotic Structural Genomics.]]		[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
	[[Category: Phillips, G N.]]		[[Category: Phillips, G N.]]
-	[[Category: Allosteric enzyme]]
-	[[Category: Amino-acid biosynthesis]]
-	[[Category: Branched-chain amino acid biosynthesis]]
-	[[Category: Center for eukaryotic structural genomic]]
-	[[Category: Cesg]]
-	[[Category: Chloroplast]]
-	[[Category: Defensive protein]]
-	[[Category: Isoleucine biosynthesis]]
-	[[Category: Jasmonic acid]]
-	[[Category: Jasmonic acid pathway]]
-	[[Category: Lyase]]
-	[[Category: Protein structure initiative]]
-	[[Category: Psi]]
-	[[Category: Pyridoxal phosphate]]
-	[[Category: Structural genomic]]
-	[[Category: Transit peptide]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:17:01 2010''

OCA at 05:08, 1 September 2010

OCA — Wed, 01 Sep 2010 05:08:54 GMT

←Older revision		Revision as of 05:08, 1 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3iau.png\|left\|200px]]

-	The ~~entry 3iau~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3iau", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3iau\| PDB=3iau \| SCENE= }}

-	~~Authors: Bianchetti, C.M, Bingman, C.A., Phillips Jr., G.N., Center for Eukaryotic Structural Genomics (CESG)~~	+	===The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum===

-	Description: The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 22 20~~:36:~~12 2009~~''	+	==About this Structure==
		+	3IAU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IAU OCA].
		+	[[Category: Solanum lycopersicum]]
		+	[[Category: Threonine ammonia-lyase]]
		+	[[Category: Bianchetti, C M.]]
		+	[[Category: Bingman, C A.]]
		+	[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
		+	[[Category: Phillips, G N.]]
		+	[[Category: Allosteric enzyme]]
		+	[[Category: Amino-acid biosynthesis]]
		+	[[Category: Branched-chain amino acid biosynthesis]]
		+	[[Category: Center for eukaryotic structural genomic]]
		+	[[Category: Cesg]]
		+	[[Category: Chloroplast]]
		+	[[Category: Defensive protein]]
		+	[[Category: Isoleucine biosynthesis]]
		+	[[Category: Jasmonic acid]]
		+	[[Category: Jasmonic acid pathway]]
		+	[[Category: Lyase]]
		+	[[Category: Protein structure initiative]]
		+	[[Category: Psi]]
		+	[[Category: Pyridoxal phosphate]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transit peptide]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:17:01 2010''