3id6 - Revision history

OCA at 15:57, 1 November 2023

OCA — Wed, 01 Nov 2023 15:57:21 GMT

←Older revision		Revision as of 15:57, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3id6' size='340' side='right'caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3id6' size='340' side='right'caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3id6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ID6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3id6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ID6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SAM:S~~-~~ADENOSYLMETHIONINE'>SAM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3id5\|3id5]]~~</~~div~~>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [https://pdbe.org/3id6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [https://www.ebi.ac.uk/pdbsum/3id6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3id6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [https://pdbe.org/3id6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [https://www.ebi.ac.uk/pdbsum/3id6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3id6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~FLPA_SULSO FLPA_SULSO~~]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>	+	[https://www.uniprot.org/uniprot/Q97ZH3_SACS2 Q97ZH3_SACS2]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35091]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Ye, K~~]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: ~~2'-o-methylation]]~~	+	[[Category: Ye K]]
-	~~[[Category: C/d guide rna]]~~	+
-	~~[[Category: Coiled-coil]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rrna processing]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Trna processing~~]]	+

OCA at 07:46, 10 November 2021

OCA — Wed, 10 Nov 2021 07:46:50 GMT

←Older revision		Revision as of 07:46, 10 November 2021
Line 1:		Line 1:

	==Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex==		==Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex==
-	<StructureSection load='3id6' size='340' side='right' caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='3id6' size='340' side='right'caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3id6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ID6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3id6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ID6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3id5\|3id5]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [~~http~~://pdbe.org/3id6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3id6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3id6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [https://pdbe.org/3id6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [https://www.ebi.ac.uk/pdbsum/3id6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3id6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>	+	[[https://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
		+	[[Category: Large Structures]]
	[[Category: Ye, K]]		[[Category: Ye, K]]
	[[Category: 2'-o-methylation]]		[[Category: 2'-o-methylation]]

OCA at 09:17, 19 December 2018

OCA — Wed, 19 Dec 2018 09:17:50 GMT

←Older revision		Revision as of 09:17, 19 December 2018
Line 1:		Line 1:
		+
	==Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex==		==Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex==
	<StructureSection load='3id6' size='340' side='right' caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='3id6' size='340' side='right' caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [http://pdbe.org/3id6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [http://www.ebi.ac.uk/pdbsum/3id6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [http://pdbe.org/3id6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [http://www.ebi.ac.uk/pdbsum/3id6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3id6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3id6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3id6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:21, 8 February 2016

OCA — Mon, 08 Feb 2016 05:21:32 GMT

←Older revision		Revision as of 05:21, 8 February 2016
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [http://www.ebi.ac.uk/pdbsum/3id6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [http://pdbe.org/3id6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [http://www.ebi.ac.uk/pdbsum/3id6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3id6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3id6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:55, 24 December 2014

OCA — Wed, 24 Dec 2014 20:55:38 GMT

←Older revision		Revision as of 20:55, 24 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3id6\| PDB=3id6 \| SCENE= }}~~	+	==Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex==
-	===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===	+	<StructureSection load='3id6' size='340' side='right' caption='[[3id6]], [[Resolution\|resolution]] 2.60Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19666563}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3id6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ID6 FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3id5\|3id5]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSO0939 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), flpA, SSO0940, C33_014 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3id6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3id6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3id6 RCSB], [http://www.ebi.ac.uk/pdbsum/3id6 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>		[[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/id/3id6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Box C/D guide RNAs are abundant noncoding RNAs that primarily function to direct the 2'-O-methylation of specific nucleotides by base-pairing with substrate RNAs. In archaea, a bipartite C/D RNA assembles with L7Ae, Nop5, and the methyltransferase fibrillarin into a modification enzyme with unique substrate specificity. Here, we determined the crystal structure of an archaeal C/D RNA-protein complex (RNP) composed of all 3 core proteins and an engineered half-guide RNA at 4 A resolution, as well as 2 protein substructures at higher resolution. The RNP structure reveals that the C-terminal domains of Nop5 in the dimeric complex provide symmetric anchoring sites for 2 L7Ae-associated kink-turn motifs of the C/D RNA. A prominent protrusion in Nop5 seems to be important for guide RNA organization and function and for discriminating the structurally related U4 snRNA. Multiple conformations of the N-terminal domain of Nop5 and its associated fibrillarin in different structures indicate the inherent flexibility of the catalytic module, suggesting that a swinging motion of the catalytic module is part of the enzyme mechanism. We also built a model of a native C/D RNP with substrate and fibrillarin in an active conformation. Our results provide insight into the overall organization and mechanism of action of C/D RNA-guided RNA methyltransferases.

-	~~==About this Structure==~~	+	Structural organization of box C/D RNA-guided RNA methyltransferase.,Ye K, Jia R, Lin J, Ju M, Peng J, Xu A, Zhang L Proc Natl Acad Sci U S A. 2009 Aug 5. PMID:19666563<ref>PMID:19666563</ref>
-	~~[[3id6]] is a 2 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Atcc_35091 Atcc 35091]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:019666563</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
-	[[Category: Ye, K.]]	+	[[Category: Ye, K]]
	[[Category: 2'-o-methylation]]		[[Category: 2'-o-methylation]]
	[[Category: C/d guide rna]]		[[Category: C/d guide rna]]

OCA at 11:35, 20 November 2013

OCA — Wed, 20 Nov 2013 11:35:37 GMT

←Older revision		Revision as of 11:35, 20 November 2013
Line 2:		Line 2:
	===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===		===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===
	{{ABSTRACT_PUBMED_19666563}}		{{ABSTRACT_PUBMED_19666563}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/FLPA_SULSO FLPA_SULSO]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.<ref>PMID:11959980</ref> <ref>PMID:15522081</ref>

	==About this Structure==		==About this Structure==
-	[[3id6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].	+	[[3id6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019666563</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019666563</ref><references group="xtra"/><references/>
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Atcc 35091]]
	[[Category: Ye, K.]]		[[Category: Ye, K.]]
	[[Category: 2'-o-methylation]]		[[Category: 2'-o-methylation]]

OCA: Protected "3id6" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 10:39:42 GMT

Protected "3id6" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:39, 13 March 2013

OCA at 10:39, 13 March 2013

OCA — Wed, 13 Mar 2013 10:39:39 GMT

←Older revision		Revision as of 10:39, 13 March 2013
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-	{{Seed}}
-	[[Image:3id6.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3id6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3id6\| PDB=3id6 \| SCENE= }}		{{STRUCTURE_3id6\| PDB=3id6 \| SCENE= }}
-
	===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===		===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19666563}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19666563 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19666563}}		{{ABSTRACT_PUBMED_19666563}}

	==About this Structure==		==About this Structure==
-	~~3ID6~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].	+	[[3id6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19666563~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019666563</ref><references group="xtra"/>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Ye, K.]]		[[Category: Ye, K.]]
Line 34:		Line 18:
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Trna processing]]		[[Category: Trna processing]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:30:14 2009''

OCA at 16:30, 21 September 2009

OCA — Mon, 21 Sep 2009 16:30:15 GMT

←Older revision		Revision as of 16:30, 21 September 2009
Line 12:		Line 12:
	===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===		===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19666563}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19666563 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19666563}}

	==About this Structure==		==About this Structure==
Line 29:		Line 35:
	[[Category: Trna processing]]		[[Category: Trna processing]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:12:44 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:30:14 2009''

OCA at 14:12, 21 September 2009

OCA — Mon, 21 Sep 2009 14:12:45 GMT

←Older revision		Revision as of 14:12, 21 September 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3id6.png\|left\|200px]]

-	The ~~entry 3id6~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3id6", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3id6\| PDB=3id6 \| SCENE= }}

-	~~Authors: Ye, K.~~	+	===Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex===

-	Description: Crystal structure of Sulfolobus solfataricus Nop5 (1-262) and fibrillarin complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 5 09~~:50:33 2009''	+	==About this Structure==
		+	3ID6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ID6 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19666563</ref><references group="xtra"/>
		+	[[Category: Sulfolobus solfataricus]]
		+	[[Category: Ye, K.]]
		+	[[Category: 2'-o-methylation]]
		+	[[Category: C/d guide rna]]
		+	[[Category: Coiled-coil]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Rna-binding]]
		+	[[Category: Rrna processing]]
		+	[[Category: Transferase]]
		+	[[Category: Trna processing]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:12:44 2009''