3iky - Revision history

OCA at 10:05, 21 February 2024

OCA — Wed, 21 Feb 2024 10:05:52 GMT

←Older revision		Revision as of 10:05, 21 February 2024
Line 3:		Line 3:
	<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>		<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IKY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IKY FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3iku\|3iku]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 18Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">parM, stbA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [https://pdbe.org/3iky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [https://www.ebi.ac.uk/pdbsum/3iky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [https://pdbe.org/3iky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [https://www.ebi.ac.uk/pdbsum/3iky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.	+	[https://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iky ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iky ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Segregation of the R1 plasmid in bacteria relies on ParM, an actin homolog that segregates plasmids by switching between cycles of polymerization and depolymerization. We find similar polymerization kinetics and stability in the presence of either ATP or GTP and a 10-fold affinity preference for ATP over GTP. We used electron cryo-microscopy to evaluate the heterogeneity within ParM filaments. In addition to variable twist, ParM has variable axial rise, and both parameters are coupled. Subunits in the same ParM filaments can exist in two different structural states, with the nucleotide-binding cleft closed or open, and the bound nucleotide biases the distribution of states. The interface between protomers is different between these states, and in neither state is it similar to F-actin. Our results suggest that the closed state of the cleft is required but not sufficient for ParM polymerization, and provide a structural basis for the dynamic instability of ParM filaments.
-
-	Structural polymorphism of the ParM filament and dynamic instability.,Galkin VE, Orlova A, Rivera C, Mullins RD, Egelman EH Structure. 2009 Sep 9;17(9):1253-64. PMID:19748346<ref>PMID:19748346</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3iky" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Plasmid segregation protein ParM\|Plasmid segregation protein ParM]]		*[[Plasmid segregation protein ParM\|Plasmid segregation protein ParM]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Egelman~~, E H~~]]	+	[[Category: Egelman EH]]
-	[[Category: Galkin~~, V E~~]]	+	[[Category: Galkin VE]]
-	[[Category: Mullins~~, R D~~]]	+	[[Category: Mullins RD]]
-	[[Category: Orlova, A]]	+	[[Category: Orlova A]]
-	[[Category: Rivera, C]]	+	[[Category: Rivera C]]
-	~~[[Category: Plasmid]]~~	+
-	~~[[Category: Plasmid partition]]~~	+
-	~~[[Category: Polymorphic protein polymer]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 03:35, 21 April 2022

OCA — Thu, 21 Apr 2022 03:35:14 GMT

←Older revision		Revision as of 03:35, 21 April 2022
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	<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>		<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3IKY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IKY FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3iku\|3iku]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [~~http~~://pdbe.org/3iky PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3iky PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [https://pdbe.org/3iky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [https://www.ebi.ac.uk/pdbsum/3iky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.	+	[[https://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:22, 10 April 2020

OCA — Fri, 10 Apr 2020 17:22:58 GMT

←Older revision		Revision as of 17:22, 10 April 2020
Line 3:		Line 3:
	<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>		<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IKY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3IKY FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://pdbe.org/3iky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://pdbe.org/3iky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:08, 6 March 2020

OCA — Fri, 06 Mar 2020 17:08:44 GMT

←Older revision		Revision as of 17:08, 6 March 2020
Line 1:		Line 1:

	==Structural model of ParM filament in the open state by cryo-EM==		==Structural model of ParM filament in the open state by cryo-EM==
-	<~~StructureSection~~ load='3iky' size='340' side='right' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>	+	<SX load='3iky' size='340' side='right' viewer='molstar' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IKY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IKY FirstGlance]. <br>
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	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Egelman, E H]]		[[Category: Egelman, E H]]
	[[Category: Galkin, V E]]		[[Category: Galkin, V E]]

OCA at 10:09, 19 December 2018

OCA — Wed, 19 Dec 2018 10:09:21 GMT

←Older revision		Revision as of 10:09, 19 December 2018
Line 1:		Line 1:
		+
	==Structural model of ParM filament in the open state by cryo-EM==		==Structural model of ParM filament in the open state by cryo-EM==
	<StructureSection load='3iky' size='340' side='right' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>		<StructureSection load='3iky' size='340' side='right' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://pdbe.org/3iky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://pdbe.org/3iky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iky ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/3iky_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/3iky_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 41:		Line 42:
	[[Category: Orlova, A]]		[[Category: Orlova, A]]
	[[Category: Rivera, C]]		[[Category: Rivera, C]]
		+	[[Category: Plasmid]]
		+	[[Category: Plasmid partition]]
	[[Category: Polymorphic protein polymer]]		[[Category: Polymorphic protein polymer]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 05:12, 9 February 2016

OCA — Tue, 09 Feb 2016 05:12:59 GMT

←Older revision		Revision as of 05:12, 9 February 2016
Line 5:		Line 5:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://pdbe.org/3iky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iky ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3iky" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Plasmid segregation protein ParM\|Plasmid segregation protein ParM]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:40, 25 December 2014

OCA — Thu, 25 Dec 2014 04:40:10 GMT

←Older revision		Revision as of 04:40, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3iky\| PDB=3iky \| SCENE= }}~~	+	==Structural model of ParM filament in the open state by cryo-EM==
-	===Structural model of ParM filament in the open state by cryo-EM===	+	<StructureSection load='3iky' size='340' side='right' caption='[[3iky]], [[Resolution\|resolution]] 18.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19748346}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IKY FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iku\|3iku]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">parM, stbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iky RCSB], [http://www.ebi.ac.uk/pdbsum/3iky PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.		[[http://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/3iky_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Segregation of the R1 plasmid in bacteria relies on ParM, an actin homolog that segregates plasmids by switching between cycles of polymerization and depolymerization. We find similar polymerization kinetics and stability in the presence of either ATP or GTP and a 10-fold affinity preference for ATP over GTP. We used electron cryo-microscopy to evaluate the heterogeneity within ParM filaments. In addition to variable twist, ParM has variable axial rise, and both parameters are coupled. Subunits in the same ParM filaments can exist in two different structural states, with the nucleotide-binding cleft closed or open, and the bound nucleotide biases the distribution of states. The interface between protomers is different between these states, and in neither state is it similar to F-actin. Our results suggest that the closed state of the cleft is required but not sufficient for ParM polymerization, and provide a structural basis for the dynamic instability of ParM filaments.

-	~~==About this~~ Structure==	+	Structural polymorphism of the ParM filament and dynamic instability.,Galkin VE, Orlova A, Rivera C, Mullins RD, Egelman EH Structure. 2009 Sep 9;17(9):1253-64. PMID:19748346<ref>PMID:19748346</ref>
-	~~[[3iky]] is a 12 chain structure with sequence from [http~~:~~//en~~.~~wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:019748346</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
-	[[Category: Egelman, E H.]]	+	[[Category: Egelman, E H]]
-	[[Category: Galkin, V E.]]	+	[[Category: Galkin, V E]]
-	[[Category: Mullins, R D.]]	+	[[Category: Mullins, R D]]
-	[[Category: Orlova, A.]]	+	[[Category: Orlova, A]]
-	[[Category: Rivera, C.]]	+	[[Category: Rivera, C]]
	[[Category: Polymorphic protein polymer]]		[[Category: Polymorphic protein polymer]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 07:27, 2 April 2014

OCA — Wed, 02 Apr 2014 07:27:01 GMT

←Older revision		Revision as of 07:27, 2 April 2014
Line 2:		Line 2:
	===Structural model of ParM filament in the open state by cryo-EM===		===Structural model of ParM filament in the open state by cryo-EM===
	{{ABSTRACT_PUBMED_19748346}}		{{ABSTRACT_PUBMED_19748346}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/PARM_ECOLX PARM_ECOLX]] Involved in the control of plasmid partition. Required for the accurate segregation of the plasmid.

	==About this Structure==		==About this Structure==
-	[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA].	+	[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:019748346</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019748346</ref><references group="xtra"/><references/>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Egelman, E H.]]		[[Category: Egelman, E H.]]
	[[Category: Galkin, V E.]]		[[Category: Galkin, V E.]]

OCA: Protected "3iky" [edit=sysop:move=sysop]

OCA — Wed, 13 Mar 2013 11:06:19 GMT

Protected "3iky" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:06, 13 March 2013

OCA at 11:06, 13 March 2013

OCA — Wed, 13 Mar 2013 11:06:15 GMT

←Older revision		Revision as of 11:06, 13 March 2013
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-	{{Seed}}
-	[[Image:3iky.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3iky", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3iky\| PDB=3iky \| SCENE= }}		{{STRUCTURE_3iky\| PDB=3iky \| SCENE= }}
-
	===Structural model of ParM filament in the open state by cryo-EM===		===Structural model of ParM filament in the open state by cryo-EM===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19748346}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19748346 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19748346}}		{{ABSTRACT_PUBMED_19748346}}

	==About this Structure==		==About this Structure==
-	~~3IKY~~ is a 12 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA].	+	[[3iky]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19748346~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019748346</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Egelman, E H.]]		[[Category: Egelman, E H.]]
Line 30:		Line 14:
	[[Category: Orlova, A.]]		[[Category: Orlova, A.]]
	[[Category: Rivera, C.]]		[[Category: Rivera, C.]]
-	[[Category: Plasmid]]
-	[[Category: Plasmid partition]]
	[[Category: Polymorphic protein polymer]]		[[Category: Polymorphic protein polymer]]
	[[Category: Structural protein]]		[[Category: Structural protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:16:15 2009''