3iyp - Revision history

OCA at 11:32, 24 January 2024

OCA — Wed, 24 Jan 2024 11:32:08 GMT

←Older revision		Revision as of 11:32, 24 January 2024
Line 3:		Line 3:
	<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/E7 E7], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] and [https://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Echovirus_E7 Echovirus E7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 7.2Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~DAF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=46018 E7])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~DAF_HUMAN DAF_HUMAN~~]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>	+	[https://www.uniprot.org/uniprot/Q9QP24_9ENTO Q9QP24_9ENTO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 27:
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: E7]]	+	[[Category: Echovirus E7]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Human echovirus 7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bator~~, C M~~]]	+	[[Category: Bator CM]]
-	[[Category: Bowman~~, V D~~]]	+	[[Category: Bowman VD]]
-	[[Category: Chipman~~, P R~~]]	+	[[Category: Chipman PR]]
-	[[Category: Cifuente~~, J O~~]]	+	[[Category: Cifuente JO]]
-	[[Category: Hafenstein, S]]	+	[[Category: Hafenstein S]]
-	[[Category: Harris~~, K G~~]]	+	[[Category: Harris KG]]
-	[[Category: Lin, F]]	+	[[Category: Lin F]]
-	[[Category: Medof~~, D E~~]]	+	[[Category: Medof DE]]
-	[[Category: Plevka, P]]	+	[[Category: Plevka P]]
-	[[Category: Rossmann~~, M G~~]]	+	[[Category: Rossmann MG]]
-	[[Category: Zhang, Y]]	+	[[Category: Zhang Y]]
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Daf]]~~	+
-	~~[[Category: Echovirus]]~~	+
-	~~[[Category: Icosahedral virus]]~~	+
-	~~[[Category: Receptor]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 03:45, 21 April 2022

OCA — Thu, 21 Apr 2022 03:45:47 GMT

←Older revision		Revision as of 03:45, 21 April 2022
Line 3:		Line 3:
	<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/E7 E7], [~~http~~://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [~~http~~://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/E7 E7], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [~~http~~://pdbe.org/3iyp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [https://pdbe.org/3iyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [https://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>	+	[[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	==See Also==		==See Also==
	*[[CD55\|CD55]]		*[[CD55\|CD55]]
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:30, 10 April 2020

OCA — Fri, 10 Apr 2020 17:30:13 GMT

←Older revision		Revision as of 17:30, 10 April 2020
Line 3:		Line 3:
	<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/E7 E7], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/E7 E7], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:11, 6 March 2020

OCA — Fri, 06 Mar 2020 17:11:42 GMT

←Older revision		Revision as of 17:11, 6 March 2020
Line 1:		Line 1:

	==The Interaction of Decay-accelerating Factor with Echovirus 7==		==The Interaction of Decay-accelerating Factor with Echovirus 7==
-	<~~StructureSection~~ load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>	+	<SX load='3iyp' size='340' side='right' viewer='molstar' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/E7 E7], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>		<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/E7 E7], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3iyp" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3iyp" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[CD55\|CD55]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: E7]]		[[Category: E7]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Human echovirus 7]]		[[Category: Human echovirus 7]]
		+	[[Category: Large Structures]]
	[[Category: Bator, C M]]		[[Category: Bator, C M]]
	[[Category: Bowman, V D]]		[[Category: Bowman, V D]]

OCA at 08:02, 18 July 2018

OCA — Wed, 18 Jul 2018 08:02:57 GMT

←Older revision		Revision as of 08:02, 18 July 2018
Line 3:		Line 3:
	<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/E7 E7], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 E7])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: E7]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Human echovirus 7]]		[[Category: Human echovirus 7]]

OCA at 20:02, 9 December 2016

OCA — Fri, 09 Dec 2016 20:02:48 GMT

←Older revision		Revision as of 20:02, 9 December 2016
Line 3:		Line 3:
	<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Echovirus_7 Echovirus 7~~] ~~and~~ [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 Echovirus 7])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Echovirus 7]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
		+	[[Category: Human echovirus 7]]
	[[Category: Bator, C M]]		[[Category: Bator, C M]]
	[[Category: Bowman, V D]]		[[Category: Bowman, V D]]

OCA at 16:48, 4 August 2016

OCA — Thu, 04 Aug 2016 16:48:40 GMT

←Older revision		Revision as of 16:48, 4 August 2016
Line 1:		Line 1:
		+
	==The Interaction of Decay-accelerating Factor with Echovirus 7==		==The Interaction of Decay-accelerating Factor with Echovirus 7==
	<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>		<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~] and [http://en.wikipedia.org/wiki/~~Human_echovirus_7 Human echovirus 7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Echovirus_7 Echovirus 7] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~9606 Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46018 Echovirus 7])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://pdbe.org/3iyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3iyp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3iyp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Echovirus 7]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Human echovirus 7]]
	[[Category: Bator, C M]]		[[Category: Bator, C M]]
	[[Category: Bowman, V D]]		[[Category: Bowman, V D]]

OCA at 11:06, 25 December 2014

OCA — Thu, 25 Dec 2014 11:06:56 GMT

←Older revision		Revision as of 11:06, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>		<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 15:
	The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref>		The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 23:
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Human echovirus 7]]		[[Category: Human echovirus 7]]
-	[[Category: Bator, C M.]]	+	[[Category: Bator, C M]]
-	[[Category: Bowman, V D.]]	+	[[Category: Bowman, V D]]
-	[[Category: Chipman, P R.]]	+	[[Category: Chipman, P R]]
-	[[Category: Cifuente, J O.]]	+	[[Category: Cifuente, J O]]
-	[[Category: Hafenstein, S.]]	+	[[Category: Hafenstein, S]]
-	[[Category: Harris, K G.]]	+	[[Category: Harris, K G]]
-	[[Category: Lin, F.]]	+	[[Category: Lin, F]]
-	[[Category: Medof, D E.]]	+	[[Category: Medof, D E]]
-	[[Category: Plevka, P.]]	+	[[Category: Plevka, P]]
-	[[Category: Rossmann, M G.]]	+	[[Category: Rossmann, M G]]
-	[[Category: Zhang, Y.]]	+	[[Category: Zhang, Y]]
	[[Category: Complex]]		[[Category: Complex]]
	[[Category: Daf]]		[[Category: Daf]]

OCA at 09:52, 21 May 2014

OCA — Wed, 21 May 2014 09:52:28 GMT

←Older revision		Revision as of 09:52, 21 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3iyp.~~png~~\|~~left~~\|~~200px~~]]	+	==The Interaction of Decay-accelerating Factor with Echovirus 7==
		+	<StructureSection load='3iyp' size='340' side='right' caption='[[3iyp]], [[Resolution\|resolution]] 7.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Echovirus 7 (EV7) belongs to the enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind into the viral canyon and are required to initiate viral uncoating during infection. However, in addition, some of the enteroviruses use an alternative or additional receptor that binds outside the canyon. Decay-accelerating factor (DAF) has been identified as a cellular receptor for EV7. The crystal structure of EV7 has been determined to 3.1 A resolution and used to interpret the 7.2 A resolution cryo-electron microscopy reconstruction of EV7 complexed with DAF. Each DAF binding site on EV7 is near a two-fold icosahedral symmetry axis, which differs from the binding site of DAF on the surface of coxsackievirus B3, indicating independent evolutionary processes by which DAF has been selected as a picornavirus accessory receptor. This suggests that there is an advantage for these viruses to recognize DAF during the initial process of infection.

-	~~<!--~~	+	The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref>
-	The ~~line below this paragraph~~, ~~containing "STRUCTURE_3iyp"~~, ~~creates the "Structure Box" on the page.~~	+
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded)~~,	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3iyp\| PDB=3iyp \| SCENE= }}~~	+

-	~~===The Interaction~~ of ~~Decay-accelerating Factor with Echovirus 7===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20881044}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 20881044 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_20881044}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3iyp]] is a 5 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020881044<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Human echovirus 7]]		[[Category: Human echovirus 7]]

OCA at 08:22, 30 October 2011

OCA — Sun, 30 Oct 2011 08:22:45 GMT

←Older revision		Revision as of 08:22, 30 October 2011
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20881044~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020881044</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Human echovirus 7]]		[[Category: Human echovirus 7]]
Line 36:		Line 36:
	[[Category: Rossmann, M G.]]		[[Category: Rossmann, M G.]]
	[[Category: Zhang, Y.]]		[[Category: Zhang, Y.]]
		+	[[Category: Complex]]
		+	[[Category: Daf]]
		+	[[Category: Echovirus]]
		+	[[Category: Icosahedral virus]]
		+	[[Category: Receptor]]
		+	[[Category: Virus]]