3izg - Revision history

OCA at 10:08, 21 February 2024

OCA — Wed, 21 Feb 2024 10:08:29 GMT

←Older revision		Revision as of 10:08, 21 February 2024
Line 9:		Line 9:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/CAPSA_BPT7 CAPSA_BPT7] Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.<ref>PMID:20962334</ref>		[https://www.uniprot.org/uniprot/CAPSA_BPT7 CAPSA_BPT7] Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.<ref>PMID:20962334</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Maturation of dsDNA bacteriophages involves assembling the virus prohead from a limited set of structural components, followed by rearrangements required for the stability that is necessary for infecting a host under challenging environmental conditions. Here, we determine the mature capsid structure of T7 at 1 nm resolution by cryo electron microscopy, and compare it with the prohead to reveal the molecular basis of T7 shell maturation. The mature capsid presents an expanded and thinner shell, with a drastic rearrangement of the major protein monomers that increases in their interacting surfaces, in turn resulting in a new bonding lattice. The rearrangements include tilting, in-plane rotation and radial expansion of the subunits, as well as a relative bending of the A and P-domains of each subunit. The unique features of this shell transformation, which does not employ the accessory proteins, inserted domains, or molecular interactions observed in other phages, suggest a simple capsid assembling strategy that may have appeared early in the evolution of these viruses.
-
-	Molecular rearrangements involved in the capsid shell maturation of bacteriophage T7.,Ionel A, Velazquez-Muriel JA, Luque D, Cuervo A, Caston JR, Valpuesta JM, Martin-Benito J, Carrascosa JL J Biol Chem. 2010 Oct 20. PMID:20962334<ref>PMID:20962334</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3izg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:11, 24 January 2024

OCA — Wed, 24 Jan 2024 14:11:37 GMT

←Older revision		Revision as of 14:11, 24 January 2024
Line 3:		Line 3:
	<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>		<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Enterobacteria_phage_t7 Enterobacteria~~ phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T7 Escherichia phage T7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [https://pdbe.org/3izg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [https://www.ebi.ac.uk/pdbsum/3izg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 10.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [https://pdbe.org/3izg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [https://www.ebi.ac.uk/pdbsum/3izg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CAPSA_BPT7 CAPSA_BPT7] Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.<ref>PMID:20962334</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 22:
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Enterobacteria~~ phage t7]]	+	[[Category: Escherichia phage T7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Agirrezabala, X]]	+	[[Category: Agirrezabala X]]
-	[[Category: Carrascosa~~, J L~~]]	+	[[Category: Carrascosa JL]]
-	[[Category: Caston~~, J R~~]]	+	[[Category: Caston JR]]
-	[[Category: Cuervo, A]]	+	[[Category: Cuervo A]]
-	[[Category: Ionel, A]]	+	[[Category: Ionel A]]
-	[[Category: Luque, D]]	+	[[Category: Luque D]]
-	[[Category: Martin-Benito, J]]	+	[[Category: Martin-Benito J]]
-	[[Category: Valpuesta~~, J M~~]]	+	[[Category: Valpuesta JM]]
-	[[Category: Velazquez-Muriel~~, J A]]~~	+	[[Category: Velazquez-Muriel JA]]
-	~~[[Category: Bacteriophage]]~~	+
-	~~[[Category: Capsid maturation]]~~	+
-	~~[[Category: Cryoelectron microscopy]]~~	+
-	~~[[Category: Icosahedral]]~~	+
-	~~[[Category: Morphogenetic intermediate]]~~	+
-	~~[[Category: Virus~~]]	+

OCA at 03:46, 21 April 2022

OCA — Thu, 21 Apr 2022 03:46:21 GMT

←Older revision		Revision as of 03:46, 21 April 2022
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	<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>		<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3IZG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [~~http~~://pdbe.org/3izg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3izg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [https://pdbe.org/3izg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [https://www.ebi.ac.uk/pdbsum/3izg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:32, 10 April 2020

OCA — Fri, 10 Apr 2020 17:32:54 GMT

←Older revision		Revision as of 17:32, 10 April 2020
Line 3:		Line 3:
	<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>		<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IZG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://pdbe.org/3izg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://pdbe.org/3izg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:26, 5 March 2020

OCA — Thu, 05 Mar 2020 04:26:22 GMT

←Older revision		Revision as of 04:26, 5 March 2020
Line 1:		Line 1:

	==Bacteriophage T7 prohead shell EM-derived atomic model==		==Bacteriophage T7 prohead shell EM-derived atomic model==
-	<~~StructureSection~~ load='3izg' size='340' side='right'caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>	+	<SX load='3izg' size='340' side='right' viewer='molstar' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>		<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
Line 18:		Line 18:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Enterobacteria phage t7]]		[[Category: Enterobacteria phage t7]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 07:10, 6 November 2019

OCA — Wed, 06 Nov 2019 07:10:11 GMT

←Older revision		Revision as of 07:10, 6 November 2019
Line 1:		Line 1:

	==Bacteriophage T7 prohead shell EM-derived atomic model==		==Bacteriophage T7 prohead shell EM-derived atomic model==
-	<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>	+	<StructureSection load='3izg' size='340' side='right'caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>		<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacteria phage t7]]		[[Category: Enterobacteria phage t7]]
		+	[[Category: Large Structures]]
	[[Category: Agirrezabala, X]]		[[Category: Agirrezabala, X]]
	[[Category: Carrascosa, J L]]		[[Category: Carrascosa, J L]]

OCA at 08:03, 18 July 2018

OCA — Wed, 18 Jul 2018 08:03:49 GMT

←Older revision		Revision as of 08:03, 18 July 2018
Line 3:		Line 3:
	<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>		<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bpt7 Bpt7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://pdbe.org/3izg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://pdbe.org/3izg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>
	</table>		</table>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt7~~]]	+	[[Category: Enterobacteria phage t7]]
	[[Category: Agirrezabala, X]]		[[Category: Agirrezabala, X]]
	[[Category: Carrascosa, J L]]		[[Category: Carrascosa, J L]]

OCA at 07:16, 5 August 2016

OCA — Fri, 05 Aug 2016 07:16:55 GMT

←Older revision		Revision as of 07:16, 5 August 2016
Line 1:		Line 1:
		+
	==Bacteriophage T7 prohead shell EM-derived atomic model==		==Bacteriophage T7 prohead shell EM-derived atomic model==
	<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>		<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t7 Enterobacteria phage t7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt7 Bpt7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://pdbe.org/3izg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3izg ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3izg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t7~~]]	+	[[Category: Bpt7]]
	[[Category: Agirrezabala, X]]		[[Category: Agirrezabala, X]]
	[[Category: Carrascosa, J L]]		[[Category: Carrascosa, J L]]

OCA at 17:41, 18 December 2014

OCA — Thu, 18 Dec 2014 17:41:23 GMT

←Older revision		Revision as of 17:41, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3izg\| PDB=3izg \| SCENE= }}~~	+	==Bacteriophage T7 prohead shell EM-derived atomic model==
-	===Bacteriophage T7 prohead shell EM-derived atomic model===	+	<StructureSection load='3izg' size='340' side='right' caption='[[3izg]], [[Resolution\|resolution]] 10.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20962334}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3izg]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZG FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3izg RCSB], [http://www.ebi.ac.uk/pdbsum/3izg PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Maturation of dsDNA bacteriophages involves assembling the virus prohead from a limited set of structural components, followed by rearrangements required for the stability that is necessary for infecting a host under challenging environmental conditions. Here, we determine the mature capsid structure of T7 at 1 nm resolution by cryo electron microscopy, and compare it with the prohead to reveal the molecular basis of T7 shell maturation. The mature capsid presents an expanded and thinner shell, with a drastic rearrangement of the major protein monomers that increases in their interacting surfaces, in turn resulting in a new bonding lattice. The rearrangements include tilting, in-plane rotation and radial expansion of the subunits, as well as a relative bending of the A and P-domains of each subunit. The unique features of this shell transformation, which does not employ the accessory proteins, inserted domains, or molecular interactions observed in other phages, suggest a simple capsid assembling strategy that may have appeared early in the evolution of these viruses.

-	~~==About this Structure==~~	+	Molecular rearrangements involved in the capsid shell maturation of bacteriophage T7.,Ionel A, Velazquez-Muriel JA, Luque D, Cuervo A, Caston JR, Valpuesta JM, Martin-Benito J, Carrascosa JL J Biol Chem. 2010 Oct 20. PMID:20962334<ref>PMID:20962334</ref>
-	~~[[3izg]] is a 7 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3IZG OCA].~~	+

-	~~==Reference==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	<~~ref group="xtra"~~>~~PMID:020962334~~</~~ref~~>~~<ref group~~=~~"xtra">PMID:017437718</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t7]]		[[Category: Enterobacteria phage t7]]
-	[[Category: Agirrezabala, X.]]	+	[[Category: Agirrezabala, X]]
-	[[Category: Carrascosa, J L.]]	+	[[Category: Carrascosa, J L]]
-	[[Category: Caston, J R.]]	+	[[Category: Caston, J R]]
-	[[Category: Cuervo, A.]]	+	[[Category: Cuervo, A]]
-	[[Category: Ionel, A.]]	+	[[Category: Ionel, A]]
-	[[Category: Luque, D.]]	+	[[Category: Luque, D]]
-	[[Category: Martin-Benito, J.]]	+	[[Category: Martin-Benito, J]]
-	[[Category: Valpuesta, J M.]]	+	[[Category: Valpuesta, J M]]
-	[[Category: Velazquez-Muriel, J A.]]	+	[[Category: Velazquez-Muriel, J A]]
	[[Category: Bacteriophage]]		[[Category: Bacteriophage]]
	[[Category: Capsid maturation]]		[[Category: Capsid maturation]]

OCA at 09:45, 27 March 2013

OCA — Wed, 27 Mar 2013 09:45:24 GMT

←Older revision		Revision as of 09:45, 27 March 2013
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-	[[Image:3izg.png\|left\|200px]]
-
-	<!--
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	{{STRUCTURE_3izg\| PDB=3izg \| SCENE= }}		{{STRUCTURE_3izg\| PDB=3izg \| SCENE= }}
-
	===Bacteriophage T7 prohead shell EM-derived atomic model===		===Bacteriophage T7 prohead shell EM-derived atomic model===
-
-
-	<!--
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	{{ABSTRACT_PUBMED_20962334}}		{{ABSTRACT_PUBMED_20962334}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20962334~~</ref><ref group="xtra">PMID:~~17437718~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020962334</ref><ref group="xtra">PMID:017437718</ref><references group="xtra"/><references/>
	[[Category: Enterobacteria phage t7]]		[[Category: Enterobacteria phage t7]]
	[[Category: Agirrezabala, X.]]		[[Category: Agirrezabala, X.]]
Line 33:		Line 18:
	[[Category: Valpuesta, J M.]]		[[Category: Valpuesta, J M.]]
	[[Category: Velazquez-Muriel, J A.]]		[[Category: Velazquez-Muriel, J A.]]
		+	[[Category: Bacteriophage]]
		+	[[Category: Capsid maturation]]
		+	[[Category: Cryoelectron microscopy]]
		+	[[Category: Icosahedral]]
		+	[[Category: Morphogenetic intermediate]]
		+	[[Category: Virus]]