3j0j - Revision history

OCA at 14:12, 24 January 2024

OCA — Wed, 24 Jan 2024 14:12:39 GMT

←Older revision		Revision as of 14:12, 24 January 2024
Line 3:		Line 3:
	<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>		<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thermus_thermophilus~~ Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0J FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 9.7Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[https~~:~~//en.wikipedia.org/wiki/H(+)~~-~~transporting_two~~-~~sector_ATPase H(+)-transporting two-sector ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [https://pdbe.org/3j0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [https://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [https://pdbe.org/3j0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [https://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	~~[[https://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [~~[https://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[https://www.uniprot.org/uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.	+	[https://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8] Produces ATP from ADP in the presence of a proton gradient across the membrane.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 27:
	</SX>		</SX>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Thermus thermophilus]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Lau~~, W C.Y~~]]	+	[[Category: Lau WCY]]
-	[[Category: Rubinstein~~, J L]]~~	+	[[Category: Rubinstein JL]]
-	~~[[Category: Flexible fitting]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Membrane protein complex]]~~	+
-	~~[[Category: Rigid body fitting~~]]	+

OCA at 03:47, 21 April 2022

OCA — Thu, 21 Apr 2022 03:47:19 GMT

←Older revision		Revision as of 03:47, 21 April 2022
Line 3:		Line 3:
	<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>		<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3J0J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J0J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [~~http~~://pdbe.org/3j0j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [https://pdbe.org/3j0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [https://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[~~http~~://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[~~http~~://www.uniprot.org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[~~http~~://www.uniprot.org/uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[~~http~~://www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[~~http~~://www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.	+	[[https://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[https://www.uniprot.org/uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[https://www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	==See Also==		==See Also==
	*[[ATPase 3D structures\|ATPase 3D structures]]		*[[ATPase 3D structures\|ATPase 3D structures]]
-	*[[V-ATPase\|V-ATPase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:39, 10 April 2020

OCA — Fri, 10 Apr 2020 17:39:02 GMT

←Older revision		Revision as of 17:39, 10 April 2020
Line 3:		Line 3:
	<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>		<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3J0J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3J0J FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://pdbe.org/3j0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://pdbe.org/3j0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:15, 6 March 2020

OCA — Fri, 06 Mar 2020 17:15:32 GMT

←Older revision		Revision as of 17:15, 6 March 2020
Line 1:		Line 1:

	==Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map==		==Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map==
-	<~~StructureSection~~ load='3j0j' size='340' side='right' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>	+	<SX load='3j0j' size='340' side='right' viewer='molstar' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J0J FirstGlance]. <br>		<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J0J FirstGlance]. <br>
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[ATPase\|ATPase]]	+	*[[ATPase 3D structures\|ATPase 3D structures]]
	*[[V-ATPase\|V-ATPase]]		*[[V-ATPase\|V-ATPase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
		+	[[Category: Large Structures]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Lau, W C.Y]]		[[Category: Lau, W C.Y]]

OCA at 18:59, 5 August 2016

OCA — Fri, 05 Aug 2016 18:59:07 GMT

←Older revision		Revision as of 18:59, 5 August 2016
Line 1:		Line 1:
		+
	==Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map==		==Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map==
	<StructureSection load='3j0j' size='340' side='right' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>		<StructureSection load='3j0j' size='340' side='right' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://pdbe.org/3j0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j0j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3j0j" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 05:01, 25 December 2014

OCA — Thu, 25 Dec 2014 05:01:47 GMT

←Older revision		Revision as of 05:01, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[http://www.uniprot.org/uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:17, 18 December 2014

OCA — Thu, 18 Dec 2014 15:17:52 GMT

←Older revision		Revision as of 15:17, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3j0j\| PDB=3j0j \| SCENE= }}~~	+	==Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map==
-	===Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map===	+	<StructureSection load='3j0j' size='340' side='right' caption='[[3j0j]], [[Resolution\|resolution]] 9.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22178924}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J0J FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j0j RCSB], [http://www.ebi.ac.uk/pdbsum/3j0j PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ion-translocating rotary ATPases serve either as ATP synthases, using energy from a transmembrane ion motive force to create the cell's supply of ATP, or as transmembrane ion pumps that are powered by ATP hydrolysis. The members of this family of enzymes each contain two rotary motors: one that couples ion translocation to rotation and one that couples rotation to ATP synthesis or hydrolysis. During ATP synthesis, ion translocation through the membrane-bound region of the complex causes rotation of a central rotor that drives conformational changes and ATP synthesis in the catalytic region of the complex. There are no structural models available for the intact membrane region of any ion-translocating rotary ATPase. Here we present a 9.7 A resolution map of the H(+)-driven ATP synthase from Thermus thermophilus obtained by electron cryomicroscopy of single particles in ice. The 600-kilodalton complex has an overall subunit composition of A(3)B(3)CDE(2)FG(2)IL(12). The membrane-bound motor consists of a ring of L subunits and the carboxy-terminal region of subunit I, which are equivalent to the c and a subunits of most other rotary ATPases, respectively. The map shows that the ring contains 12 L subunits and that the I subunit has eight transmembrane helices. The L(12) ring and I subunit have a surprisingly small contact area in the middle of the membrane, with helices from the I subunit making contacts with two different L subunits. The transmembrane helices of subunit I form bundles that could serve as half-channels across the membrane, with the first half-channel conducting protons from the periplasm to the L(12) ring and the second half-channel conducting protons from the L(12) ring to the cytoplasm. This structure therefore suggests the mechanism by which a transmembrane proton motive force is converted to rotation in rotary ATPases.

-	~~==Function==~~	+	Subnanometre-resolution structure of the intact Thermus thermophilus H(+)-driven ATP synthase.,Lau WC, Rubinstein JL Nature. 2011 Dec 18. doi: 10.1038/nature10699. PMID:22178924<ref>PMID:22178924</ref>
-	~~[[http://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence~~ of ~~a proton gradient across~~ the ~~membrane. [[http://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces~~ ATP ~~from ADP in the presence of a proton gradient across the membrane~~. ~~[[http://www~~.~~uniprot~~.~~org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[http~~:~~//www~~.~~uniprot.org~~/~~uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane~~. ~~[[http~~:~~//www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http~~:/~~/www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.~~	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3j0j]] is~~ a ~~13 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA].~~	+	</div>

	==See Also==		==See Also==
-	*[[~~ATP synthase~~\|~~ATP synthase~~]]	+	*[[ATPase\|ATPase]]
	*[[V-ATPase\|V-ATPase]]		*[[V-ATPase\|V-ATPase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:022178924</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Lau, W C.Y.]]	+	[[Category: Lau, W C.Y]]
-	[[Category: Rubinstein, J L.]]	+	[[Category: Rubinstein, J L]]
	[[Category: Flexible fitting]]		[[Category: Flexible fitting]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Membrane protein complex]]		[[Category: Membrane protein complex]]
	[[Category: Rigid body fitting]]		[[Category: Rigid body fitting]]

OCA at 04:09, 18 July 2013

OCA — Thu, 18 Jul 2013 04:09:19 GMT

←Older revision		Revision as of 04:09, 18 July 2013
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	===Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map===		===Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map===
	{{ABSTRACT_PUBMED_22178924}}		{{ABSTRACT_PUBMED_22178924}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/VATE_THET8 VATE_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATF_THET8 VATF_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATA_THET8 VATA_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. [[http://www.uniprot.org/uniprot/VATD_THET8 VATD_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATC_THET8 VATC_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. [[http://www.uniprot.org/uniprot/VATB_THET8 VATB_THET8]] Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

	==About this Structure==		==About this Structure==
Line 11:		Line 14:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:022178924</ref><references group="xtra"/>	+	<ref group="xtra">PMID:022178924</ref><references group="xtra"/><references/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Lau, W C.Y.]]		[[Category: Lau, W C.Y.]]

OCA at 09:25, 11 March 2013

OCA — Mon, 11 Mar 2013 09:25:18 GMT

←Older revision		Revision as of 09:25, 11 March 2013
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-	[[Image:3j0j.png\|left\|200px]]
-
	{{STRUCTURE_3j0j\| PDB=3j0j \| SCENE= }}		{{STRUCTURE_3j0j\| PDB=3j0j \| SCENE= }}
-
	===Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map===		===Fitted atomic models of Thermus thermophilus V-ATPase subunits into cryo-EM map===
-
	{{ABSTRACT_PUBMED_22178924}}		{{ABSTRACT_PUBMED_22178924}}

OCA at 12:57, 20 October 2012

OCA — Sat, 20 Oct 2012 12:57:31 GMT

←Older revision		Revision as of 12:57, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3j0j]] is a 13 chain structure ~~of [[ATP synthase]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA].	+	[[3j0j]] is a 13 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J0J OCA].

	==See Also==		==See Also==
	*[[ATP synthase\|ATP synthase]]		*[[ATP synthase\|ATP synthase]]
		+	*[[V-ATPase\|V-ATPase]]

	==Reference==		==Reference==