3j2o - Revision history

OCA at 10:09, 21 February 2024

OCA — Wed, 21 Feb 2024 10:09:49 GMT

←Older revision		Revision as of 10:09, 21 February 2024
Line 9:		Line 9:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').		[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	A hexamer of the bacteriophage T4 tail terminator protein, gp15, attaches to the top of the phage tail stabilizing the contractile sheath and forming the interface for binding of the independently assembled head. Here we report the crystal structure of the gp15 hexamer, describe its interactions in T4 virions that have either an extended tail or a contracted tail, and discuss its structural relationship to other phage proteins. The neck of T4 virions is decorated by the "collar" and "whiskers", made of fibritin molecules. Fibritin acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. The collar and whiskers are environment-sensing devices, regulating the retraction of the long tail fibers under unfavorable conditions, thus preventing infection. Cryo-electron microscopy analysis suggests that twelve fibritin molecules attach to the phage neck with six molecules forming the collar and six molecules forming the whiskers.
-
-	The Molecular Architecture of the Bacteriophage T4 Neck.,Fokine A, Zhang Z, Kanamaru S, Bowman VD, Aksyuk AA, Arisaka F, Rao VB, Rossmann MG J Mol Biol. 2013 Feb 19. pii: S0022-2836(13)00098-3. doi:, 10.1016/j.jmb.2013.02.012. PMID:23434847<ref>PMID:23434847</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3j2o" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Fibritin\|Fibritin]]		*[[Fibritin\|Fibritin]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>

OCA at 14:14, 24 January 2024

OCA — Wed, 24 Jan 2024 14:14:21 GMT

←Older revision		Revision as of 14:14, 24 January 2024
Line 3:		Line 3:
	<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>		<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 25Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">wac ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=10665 BPT4])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [https://pdbe.org/3j2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [https://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [https://pdbe.org/3j2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [https://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').	+	[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 25:
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aksyuk~~, A A~~]]	+	[[Category: Aksyuk AA]]
-	[[Category: Arisaka, F]]	+	[[Category: Arisaka F]]
-	[[Category: Bowman~~, V D~~]]	+	[[Category: Bowman VD]]
-	[[Category: Fokine, A]]	+	[[Category: Fokine A]]
-	[[Category: Kanamaru, S]]	+	[[Category: Kanamaru S]]
-	[[Category: Rao~~, V B~~]]	+	[[Category: Rao VB]]
-	[[Category: Rossmann~~, M G~~]]	+	[[Category: Rossmann MG]]
-	[[Category: Zhang, Z]]	+	[[Category: Zhang Z]]
-	~~[[Category: Bacteriophage t4]]~~	+
-	~~[[Category: Collar whisker]]~~	+
-	~~[[Category: Fibritin]]~~	+
-	~~[[Category: Gpwac]]~~	+
-	~~[[Category: Phage neck]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 03:48, 21 April 2022

OCA — Thu, 21 Apr 2022 03:48:40 GMT

←Older revision		Revision as of 03:48, 21 April 2022
Line 3:		Line 3:
	<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>		<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3J2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [~~http~~://pdbe.org/3j2o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [https://pdbe.org/3j2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [https://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').	+	[[https://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:48, 10 April 2020

OCA — Fri, 10 Apr 2020 17:48:28 GMT

←Older revision		Revision as of 17:48, 10 April 2020
Line 3:		Line 3:
	<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>		<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3J2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://pdbe.org/3j2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://pdbe.org/3j2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:19, 6 March 2020

OCA — Fri, 06 Mar 2020 17:19:43 GMT

←Older revision		Revision as of 17:19, 6 March 2020
Line 1:		Line 1:

	==Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers==		==Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers==
-	<~~StructureSection~~ load='3j2o' size='340' side='right' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>	+	<SX load='3j2o' size='340' side='right' viewer='molstar' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J2O FirstGlance]. <br>		<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
Line 25:		Line 25:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bpt4]]		[[Category: Bpt4]]
		+	[[Category: Large Structures]]
	[[Category: Aksyuk, A A]]		[[Category: Aksyuk, A A]]
	[[Category: Arisaka, F]]		[[Category: Arisaka, F]]

OCA at 19:33, 4 August 2016

OCA — Thu, 04 Aug 2016 19:33:45 GMT

←Older revision		Revision as of 19:33, 4 August 2016
Line 1:		Line 1:
		+
	==Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers==		==Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers==
	<StructureSection load='3j2o' size='340' side='right' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>		<StructureSection load='3j2o' size='340' side='right' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 ~~Enterobacteria phage T4~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://pdbe.org/3j2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3j2o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3j2o" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Aksyuk, A A]]		[[Category: Aksyuk, A A]]
	[[Category: Arisaka, F]]		[[Category: Arisaka, F]]

OCA at 12:26, 25 December 2014

OCA — Thu, 25 Dec 2014 12:26:36 GMT

←Older revision		Revision as of 12:26, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:00, 18 December 2014

OCA — Thu, 18 Dec 2014 17:00:42 GMT

←Older revision		Revision as of 17:00, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3j2o\| PDB=3j2o \| SCENE= }}~~	+	==Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers==
-	===Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers===	+	<StructureSection load='3j2o' size='340' side='right' caption='[[3j2o]], [[Resolution\|resolution]] 25.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23434847}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3J2O FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ox3\|1ox3]], [[1aa0\|1aa0]], [[2bsg\|2bsg]], [[3j2m\|3j2m]], [[3j2n\|3j2n]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">wac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 Enterobacteria phage T4])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3j2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3j2o RCSB], [http://www.ebi.ac.uk/pdbsum/3j2o PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A hexamer of the bacteriophage T4 tail terminator protein, gp15, attaches to the top of the phage tail stabilizing the contractile sheath and forming the interface for binding of the independently assembled head. Here we report the crystal structure of the gp15 hexamer, describe its interactions in T4 virions that have either an extended tail or a contracted tail, and discuss its structural relationship to other phage proteins. The neck of T4 virions is decorated by the "collar" and "whiskers", made of fibritin molecules. Fibritin acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. The collar and whiskers are environment-sensing devices, regulating the retraction of the long tail fibers under unfavorable conditions, thus preventing infection. Cryo-electron microscopy analysis suggests that twelve fibritin molecules attach to the phage neck with six molecules forming the collar and six molecules forming the whiskers.

-	~~==Function==~~	+	The Molecular Architecture of the Bacteriophage T4 Neck.,Fokine A, Zhang Z, Kanamaru S, Bowman VD, Aksyuk AA, Arisaka F, Rao VB, Rossmann MG J Mol Biol. 2013 Feb 19. pii: S0022-2836(13)00098-3. doi:, 10.1016/j.jmb.2013.02.012. PMID:23434847<ref>PMID:23434847</ref>
-	~~[[http://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment~~ of ~~long tail fibers to virus particle. Forms~~ the ~~fibrous structure on the neck of the virion called whiskers~~. ~~During phage assembly~~, ~~6 fibritin molecules attach to each virion neck through their N-terminal domains~~, ~~to form a collar with six fibers~~ (~~'whiskers'~~).	+

-	==~~About this Structure~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[~~3j2o~~]] ~~is a 6 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA].~~	+	</div>
		+
		+	==See Also==
		+	*[[Fibritin\|Fibritin]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
-	[[Category: Aksyuk, A A.]]	+	[[Category: Aksyuk, A A]]
-	[[Category: Arisaka, F.]]	+	[[Category: Arisaka, F]]
-	[[Category: Bowman, V D.]]	+	[[Category: Bowman, V D]]
-	[[Category: Fokine, A.]]	+	[[Category: Fokine, A]]
-	[[Category: Kanamaru, S.]]	+	[[Category: Kanamaru, S]]
-	[[Category: Rao, V B.]]	+	[[Category: Rao, V B]]
-	[[Category: Rossmann, M G.]]	+	[[Category: Rossmann, M G]]
-	[[Category: Zhang, Z.]]	+	[[Category: Zhang, Z]]
	[[Category: Bacteriophage t4]]		[[Category: Bacteriophage t4]]
	[[Category: Collar whisker]]		[[Category: Collar whisker]]

OCA at 06:08, 16 May 2013

OCA — Thu, 16 May 2013 06:08:35 GMT

←Older revision		Revision as of 06:08, 16 May 2013
Line 1:		Line 1:
-	[[Image:3j2o.jpg\|left\|200px]]
-
	{{STRUCTURE_3j2o\| PDB=3j2o \| SCENE= }}		{{STRUCTURE_3j2o\| PDB=3j2o \| SCENE= }}
-
	===Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers===		===Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers===
		+	{{ABSTRACT_PUBMED_23434847}}

-	~~{{ABSTRACT_PUBMED_23434847}}~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/WAC_BPT4 WAC_BPT4]] Chaperone responsible for attachment of long tail fibers to virus particle. Forms the fibrous structure on the neck of the virion called whiskers. During phage assembly, 6 fibritin molecules attach to each virion neck through their N-terminal domains, to form a collar with six fibers ('whiskers').

	==About this Structure==		==About this Structure==

OCA at 14:10, 6 March 2013

OCA — Wed, 06 Mar 2013 14:10:40 GMT

←Older revision		Revision as of 14:10, 6 March 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3j2o.jpg\|left\|200px]]

-	~~The entry~~ 3j2o ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3j2o\| PDB=3j2o \| SCENE= }}

-	~~Authors: Fokine, A., Zhang, Z., Kanamaru, S., Bowman, V.D., Aksyuk, A.A., Arisaka, F., Rao, V.B., Rossmann, M.G.~~	+	===Model of the bacteriophage T4 fibritin based on the cryo-EM reconstruction of the contracted T4 tail containing the phage collar and whiskers===

-	~~Description~~: ~~Model of the bacteriophage T4 fibritin based on the cryo~~-~~EM reconstruction of the contracted T4 tail containing the~~ phage ~~collar and whiskers~~	+	{{ABSTRACT_PUBMED_23434847}}
		+
		+	==About this Structure==
		+	[[3j2o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J2O OCA].
		+	[[Category: Enterobacteria phage t4]]
		+	[[Category: Aksyuk, A A.]]
		+	[[Category: Arisaka, F.]]
		+	[[Category: Bowman, V D.]]
		+	[[Category: Fokine, A.]]
		+	[[Category: Kanamaru, S.]]
		+	[[Category: Rao, V B.]]
		+	[[Category: Rossmann, M G.]]
		+	[[Category: Zhang, Z.]]
		+	[[Category: Bacteriophage t4]]
		+	[[Category: Collar whisker]]
		+	[[Category: Fibritin]]
		+	[[Category: Gpwac]]
		+	[[Category: Phage neck]]
		+	[[Category: Viral protein]]