3jqx - Revision history

OCA at 08:02, 6 September 2023

OCA — Wed, 06 Sep 2023 08:02:14 GMT

←Older revision		Revision as of 08:02, 6 September 2023
Line 1:		Line 1:

	==Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium==		==Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium==
-	<StructureSection load='3jqx' size='340' side='right' caption='[[3jqx]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='3jqx' size='340' side='right'caption='[[3jqx]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jqx]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jqx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Hathewaya_histolytica Hathewaya histolytica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JQX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nqj\|1nqj]]~~, [[~~2o8o~~\|~~2o8o]], [[3jqu\|3jqu]], [[3jqw\|3jqw~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1498~~ "~~Bacillus histolyticus~~" ~~Weinberg and Seguin 1916])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jqx OCA], [https://pdbe.org/3jqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jqx RCSB], [https://www.ebi.ac.uk/pdbsum/3jqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jqx ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Microbial_collagenase Microbial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.3 3.4.24.3]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jqx OCA], [~~http~~://pdbe.org/3jqx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jqx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jqx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jqx ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/COLH_HATHI COLH_HATHI] Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization. Has both tripeptidylcarboxypeptidase on Gly-X-Y and endopeptidase activities; the endopeptidase cuts within the triple helix region of collagen while tripeptidylcarboxypeptidase successively digests the exposed ends, thus clostridial collagenases can digest large sections of collagen (PubMed:3002446). The full-length protein has collagenase activity, while both the 116 kDa and 98 kDa forms act on gelatin (PubMed:7961400). In vitro digestion of soluble calf skin collagen fibrils requires both ColG and ColH; ColG forms missing the second collagen-binding domain is also synergistic with ColH, although their overall efficiency is decreased (PubMed:18374061, PubMed:22099748). Digestion of collagen requires Ca(2+) and is inhibited by EDTA (PubMed:9452493). The activator domain (residues 119-388) and catalytic subdomain (330-601) open and close around substrate allowing digestion when the protein is closed (PubMed:23703618).<ref>PMID:18374061</ref> <ref>PMID:18937627</ref> <ref>PMID:22099748</ref> <ref>PMID:23703618</ref> <ref>PMID:24125730</ref> <ref>PMID:28820255</ref> <ref>PMID:3002446</ref> <ref>PMID:7961400</ref> <ref>PMID:9452493</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Collagenase ~~(non-MMP)~~\|Collagenase ~~(non-MMP)~~]]	+	*[[Collagenase 3D structures\|Collagenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus histolyticus weinberg and seguin 1916~~]]	+	[[Category: Hathewaya histolytica]]
-	[[Category: ~~Microbial collagenase~~]]	+	[[Category: Large Structures]]
-	[[Category: Bauer, R]]	+	[[Category: Bauer R]]
-	[[Category: Matsushita, O]]	+	[[Category: Matsushita O]]
-	[[Category: Philominathan~~, S T.L~~]]	+	[[Category: Philominathan STL]]
-	[[Category: Sakon, J]]	+	[[Category: Sakon J]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Collagen]]~~	+
-	~~[[Category: Dual calcium-binding motif~~]]	+

OCA at 09:23, 26 December 2018

OCA — Wed, 26 Dec 2018 09:23:54 GMT

←Older revision		Revision as of 09:23, 26 December 2018
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/3jqx_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/3jqx_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:19, 9 December 2016

OCA — Fri, 09 Dec 2016 20:19:45 GMT

←Older revision		Revision as of 20:19, 9 December 2016
Line 1:		Line 1:
		+
	==Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium==		==Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium==
	<StructureSection load='3jqx' size='340' side='right' caption='[[3jqx]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3jqx' size='340' side='right' caption='[[3jqx]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_histolyticum Clostridium histolyticum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_histolyticus"_weinberg_and_seguin_1916 "bacillus histolyticus" weinberg and seguin 1916]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JQX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nqj\|1nqj]], [[2o8o\|2o8o]], [[3jqu\|3jqu]], [[3jqw\|3jqw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nqj\|1nqj]], [[2o8o\|2o8o]], [[3jqu\|3jqu]], [[3jqw\|3jqw]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 ~~Clostridium histolyticum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 "Bacillus histolyticus" Weinberg and Seguin 1916])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Microbial_collagenase Microbial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.3 3.4.24.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Microbial_collagenase Microbial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.3 3.4.24.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jqx RCSB], [http://www.ebi.ac.uk/pdbsum/3jqx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jqx OCA], [http://pdbe.org/3jqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jqx RCSB], [http://www.ebi.ac.uk/pdbsum/3jqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jqx ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jqx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3jqx" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Clostridium histolyticum~~]]	+	[[Category: Bacillus histolyticus weinberg and seguin 1916]]
	[[Category: Microbial collagenase]]		[[Category: Microbial collagenase]]
	[[Category: Bauer, R]]		[[Category: Bauer, R]]

OCA at 09:17, 8 December 2014

OCA — Mon, 08 Dec 2014 09:17:08 GMT

←Older revision		Revision as of 09:17, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3jqx.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium==
		+	<StructureSection load='3jqx' size='340' side='right' caption='[[3jqx]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3jqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JQX FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nqj\|1nqj]], [[2o8o\|2o8o]], [[3jqu\|3jqu]], [[3jqw\|3jqw]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">colH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1498 Clostridium histolyticum])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Microbial_collagenase Microbial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.3 3.4.24.3] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jqx RCSB], [http://www.ebi.ac.uk/pdbsum/3jqx PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/3jqx_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Clostridium histolyticum secretes collagenases, ColG and ColH that cause extensive tissue destruction in myonecrosis. The C-terminal collagen-binding domain (CBD) of collagenase is required for insoluble collagen fibril binding and subsequent collagenolysis. The high resolution crystal structures of ColG-CBD (s3b) and ColH-CBD (s3) are reported in this paper. The new X-ray structure of s3 was solved at 2.0 A resolution (R=17.4%, R(free)=23.3%), while the resolution of the previously determined s3b was extended to 1.4 A (R=17.9%, R(free)=21.0%). Despite sharing only 30% sequence identity, the molecules resemble one another closely (r.m.s.d. C(alpha) = 1.5 A). All but one residue whose sidechain chelates with Ca(2+) are conserved. The dual Ca(2+) binding site in s3 is completed by an unconserved aspartate. Differential scanning calorimetric measurements showed that s3 gains thermal stability, comparable to s3b, by binding to Ca(2+) (holo T(M)=94.1 degrees C, apo T(M)=70.2 degrees C). Holo s3 is also stabilized against chemical denaturants, urea and guanidine HCl. The three most critical residues for collagen interaction in s3b are conserved in s3. The general shape of the binding pocket is retained by altered loop structures and side chain positions. Small angle X-ray scattering data revealed that s3 also binds asymmetrically to mini-collagen. Besides the calcium-binding sites and the collagen-binding pocket, architecturally important hydrophobic residues and hydrogen-bonding network around the cis-peptide bond are well-conserved within metallopeptidase subfamily M9B. CBDs were previously shown to bind to extracellular matrix of various tissues. Compactness and extreme stability in physiological Ca(2+) concentration possibly make both CBDs suitable for targeted growth factor delivery.

-	~~{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}~~	+	Structural comparison of ColH and ColG collagen-binding domains from Clostridium histolyticum.,Bauer R, Wilson JJ, Philominathan ST, Davis D, Matsushita O, Sakon J J Bacteriol. 2012 Nov 9. PMID:23144249<ref>PMID:23144249</ref>

-	~~===Crystal structure~~ of ~~Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in~~ the ~~presence of calcium and cadmium===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23144249}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3jqx]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Clostridium_histolyticum Clostridium histolyticum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].~~	+

	==See Also==		==See Also==
	*[[Collagenase (non-MMP)\|Collagenase (non-MMP)]]		*[[Collagenase (non-MMP)\|Collagenase (non-MMP)]]
-	*[[Tetracycline repressor protein\|Tetracycline repressor protein]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Clostridium histolyticum]]		[[Category: Clostridium histolyticum]]
	[[Category: Microbial collagenase]]		[[Category: Microbial collagenase]]
-	[[Category: Bauer, R.]]	+	[[Category: Bauer, R]]
-	[[Category: Matsushita, O.]]	+	[[Category: Matsushita, O]]
-	[[Category: Philominathan, S T.L.]]	+	[[Category: Philominathan, S T.L]]
-	[[Category: Sakon, J.]]	+	[[Category: Sakon, J]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Collagen]]		[[Category: Collagen]]
	[[Category: Dual calcium-binding motif]]		[[Category: Dual calcium-binding motif]]

OCA at 09:44, 5 December 2012

OCA — Wed, 05 Dec 2012 09:44:17 GMT

←Older revision		Revision as of 09:44, 5 December 2012
Line 5:		Line 5:
	===Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium===		===Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium===

		+	{{ABSTRACT_PUBMED_23144249}}

	==About this Structure==		==About this Structure==

OCA at 18:18, 20 October 2012

OCA — Sat, 20 Oct 2012 18:18:13 GMT

←Older revision		Revision as of 18:18, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3jqx]] is a 3 chain structure ~~of [[Collagenase (non-MMP)]] and [[Tetracycline repressor protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].	+	[[3jqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].

	==See Also==		==See Also==

OCA at 03:40, 27 July 2012

OCA — Fri, 27 Jul 2012 03:40:50 GMT

←Older revision		Revision as of 03:40, 27 July 2012
Line 1:		Line 1:
	[[Image:3jqx.png\|left\|200px]]		[[Image:3jqx.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3jqx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}		{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}

Line 16:		Line 10:

	==See Also==		==See Also==
-	*[[Collagenase (non-MMP)]]	+	*[[Collagenase (non-MMP)\|Collagenase (non-MMP)]]
-	*[[Tetracycline repressor protein]]	+	*[[Tetracycline repressor protein\|Tetracycline repressor protein]]
	[[Category: Clostridium histolyticum]]		[[Category: Clostridium histolyticum]]
	[[Category: Microbial collagenase]]		[[Category: Microbial collagenase]]

OCA: Protected "3jqx" [edit=sysop:move=sysop]

OCA — Wed, 11 Jan 2012 05:34:26 GMT

Protected "3jqx" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:34, 11 January 2012

OCA at 05:34, 11 January 2012

OCA — Wed, 11 Jan 2012 05:34:25 GMT

←Older revision		Revision as of 05:34, 11 January 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3jqx.png\|left\|200px]]
-	[[Image:3jqx.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 10:		Line 9:
	{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}		{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}

-	===Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and ~~cademium~~===	+	===Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cadmium===


	==About this Structure==		==About this Structure==
-	~~3JQX~~ is a 3 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].	+	[[3jqx]] is a 3 chain structure of [[Collagenase (non-MMP)]] and [[Tetracycline repressor protein]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].
		+
		+	==See Also==
		+	*[[Collagenase (non-MMP)]]
		+	*[[Tetracycline repressor protein]]
	[[Category: Clostridium histolyticum]]		[[Category: Clostridium histolyticum]]
	[[Category: Microbial collagenase]]		[[Category: Microbial collagenase]]
Line 25:		Line 28:
	[[Category: Collagen]]		[[Category: Collagen]]
	[[Category: Dual calcium-binding motif]]		[[Category: Dual calcium-binding motif]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 08:12:47 2010''

OCA at 05:03, 29 September 2010

OCA — Wed, 29 Sep 2010 05:03:32 GMT

←Older revision		Revision as of 05:03, 29 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3jqx.jpg\|left\|200px]]

-	The ~~entry 3jqx~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3jqx", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3jqx\| PDB=3jqx \| SCENE= }}

-	~~Authors: Sakon, J., Philominathan, S.T.L., Bauer, R., Matsushita, O~~.	+	===Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cademium===

-	Description: Crystal structure of Clostridium histolyticum colH collagenase collagen binding domain 3 at 2.2 Angstrom resolution in the presence of calcium and cademium

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 08:59:~~39 2009~~''	+	==About this Structure==
		+	3JQX is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Clostridium_histolyticum Clostridium histolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQX OCA].
		+	[[Category: Clostridium histolyticum]]
		+	[[Category: Microbial collagenase]]
		+	[[Category: Bauer, R.]]
		+	[[Category: Matsushita, O.]]
		+	[[Category: Philominathan, S T.L.]]
		+	[[Category: Sakon, J.]]
		+	[[Category: Beta barrel]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Collagen]]
		+	[[Category: Dual calcium-binding motif]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 08:12:47 2010''