3jtr - Revision history

OCA at 16:05, 1 November 2023

OCA — Wed, 01 Nov 2023 16:05:19 GMT

←Older revision		Revision as of 16:05, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3jtr' size='340' side='right'caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3jtr' size='340' side='right'caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp.~~_gk-16~~ Pseudomonas sp. ~~gk-16~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._GK16 Pseudomonas sp. GK16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[https://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [https://pdbe.org/3jtr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [https://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [https://pdbe.org/3jtr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [https://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A4ZVL3_PSEU7 A4ZVL3_PSEU7]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Pseudomonas sp. ~~gk-16~~]]	+	[[Category: Pseudomonas sp. GK16]]
-	[[Category: Cho~~, K J~~]]	+	[[Category: Cho KJ]]
-	[[Category: Kim~~, J K~~]]	+	[[Category: Kim JK]]
-	[[Category: Kim~~, K H~~]]	+	[[Category: Kim KH]]
-	[[Category: Lee~~, J H~~]]	+	[[Category: Lee JH]]
-	[[Category: Park~~, S S~~]]	+	[[Category: Park SS]]
-	[[Category: Shin~~, H J]]~~	+	[[Category: Shin HJ]]
-	~~[[Category: Autoproteolysis]]~~	+
-	~~[[Category: Cephalosporin acylase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:48, 10 November 2021

OCA — Wed, 10 Nov 2021 07:48:57 GMT

←Older revision		Revision as of 07:48, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='3jtr' size='340' side='right'caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3jtr' size='340' side='right'caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JTR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [~~http~~://pdbe.org/3jtr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [https://pdbe.org/3jtr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [https://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:54, 7 August 2019

OCA — Wed, 07 Aug 2019 06:54:54 GMT

←Older revision		Revision as of 06:54, 7 August 2019
Line 1:		Line 1:

	==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==		==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==
-	<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='3jtr' size='340' side='right'caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtr_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cephalosporin acylase 3D structures\|Cephalosporin acylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]		[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
		+	[[Category: Large Structures]]
	[[Category: Pseudomonas sp. gk-16]]		[[Category: Pseudomonas sp. gk-16]]
	[[Category: Cho, K J]]		[[Category: Cho, K J]]

OCA at 08:19, 1 November 2017

OCA — Wed, 01 Nov 2017 08:19:30 GMT

←Older revision		Revision as of 08:19, 1 November 2017
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Cephalosporin acylase\|Cephalosporin acylase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:23, 5 August 2016

OCA — Fri, 05 Aug 2016 00:23:15 GMT

←Older revision		Revision as of 00:23, 5 August 2016
Line 1:		Line 1:
		+
	==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==		==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==
	<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._gk-16 Pseudomonas sp. gk-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [http://www.ebi.ac.uk/pdbsum/3jtr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [http://pdbe.org/3jtr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [http://www.ebi.ac.uk/pdbsum/3jtr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtr ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jtr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3jtr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cephalosporin acylase\|Cephalosporin acylase]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]		[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
-	[[Category: Pseudomonas sp]]	+	[[Category: Pseudomonas sp. gk-16]]
	[[Category: Cho, K J]]		[[Category: Cho, K J]]
	[[Category: Kim, J K]]		[[Category: Kim, J K]]

OCA at 16:54, 18 December 2014

OCA — Thu, 18 Dec 2014 16:54:37 GMT

←Older revision		Revision as of 16:54, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3jtr\| PDB=3jtr \| SCENE= }}~~	+	==Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis==
-	===Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis===	+	<StructureSection load='3jtr' size='340' side='right' caption='[[3jtr]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_19800869}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JTR FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2adv\|2adv]], [[2ae4\|2ae4]], [[2ae3\|2ae3]], [[3jtq\|3jtq]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaryl-7-aminocephalosporanic-acid_acylase Glutaryl-7-aminocephalosporanic-acid acylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.93 3.5.1.93] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jtr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jtr RCSB], [http://www.ebi.ac.uk/pdbsum/3jtr PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/3jtr_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cephalosporin acylase (CA), a member of the N-terminal nucleophile hydrolase family, is activated through two steps of intramolecular autoproteolysis, the first mediated by a serine residue, and the second by a glutamate, which releases the pro-segment and produces an active enzyme. In this study, we have determined the crystal structures of mutants which could affect primary or secondary auto-cleavage and of sequential intermediates of a slow-processing mutant at 2.0-2.5A resolutions. The pro-segments of the mutants undergo dynamic conformational changes during activation and adopt surprisingly different loop conformations from one another. However, the autoproteolytic site was found to form a catalytically competent conformation with a solvent water molecule, which was essentially conserved in the CA mutants.

-	~~==About this Structure==~~	+	Structural features of cephalosporin acylase reveal the basis of autocatalytic activation.,Cho KJ, Kim JK, Lee JH, Shin HJ, Park SS, Kim KH Biochem Biophys Res Commun. 2009 Dec 11;390(2):342-8. Epub 2009 Oct 2. PMID:19800869<ref>PMID:19800869</ref>
-	~~[[3jtr]] is a~~ 2 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:019800869</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]		[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
-	[[Category: Pseudomonas sp.]]	+	[[Category: Pseudomonas sp]]
-	[[Category: Cho, K J.]]	+	[[Category: Cho, K J]]
-	[[Category: Kim, J K.]]	+	[[Category: Kim, J K]]
-	[[Category: Kim, K H.]]	+	[[Category: Kim, K H]]
-	[[Category: Lee, J H.]]	+	[[Category: Lee, J H]]
-	[[Category: Park, S S.]]	+	[[Category: Park, S S]]
-	[[Category: Shin, H J.]]	+	[[Category: Shin, H J]]
	[[Category: Autoproteolysis]]		[[Category: Autoproteolysis]]
	[[Category: Cephalosporin acylase]]		[[Category: Cephalosporin acylase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA: Protected "3jtr" [edit=sysop:move=sysop]

OCA — Wed, 27 Mar 2013 09:40:07 GMT

Protected "3jtr" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:40, 27 March 2013

OCA at 09:40, 27 March 2013

OCA — Wed, 27 Mar 2013 09:40:03 GMT

←Older revision		Revision as of 09:40, 27 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3jtr.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3jtr", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3jtr\| PDB=3jtr \| SCENE= }}		{{STRUCTURE_3jtr\| PDB=3jtr \| SCENE= }}
-
	===Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis===		===Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19800869}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19800869 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19800869}}		{{ABSTRACT_PUBMED_19800869}}

	==About this Structure==		==About this Structure==
-	~~3JTR~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA].	+	[[3jtr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19800869~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019800869</ref><references group="xtra"/><references/>
	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]		[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
	[[Category: Pseudomonas sp.]]		[[Category: Pseudomonas sp.]]
Line 35:		Line 19:
	[[Category: Cephalosporin acylase]]		[[Category: Cephalosporin acylase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:43:38 2010''

OCA at 17:43, 27 January 2010

OCA — Wed, 27 Jan 2010 17:43:39 GMT

←Older revision		Revision as of 17:43, 27 January 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3jtr.jpg\|left\|200px]]

-	The ~~entry 3jtr~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3jtr", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3jtr\| PDB=3jtr \| SCENE= }}

-	~~Authors: Cho, K.J., Kim, J.K., Lee, J.-H., Shin, H.J., Park, S.S., Kim, K.H.~~	+	===Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis===

-	Description: Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 18 18~~:48:~~49 2009~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19800869}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19800869 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19800869}}
		+
		+	==About this Structure==
		+	3JTR is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTR OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19800869</ref><references group="xtra"/>
		+	[[Category: Glutaryl-7-aminocephalosporanic-acid acylase]]
		+	[[Category: Pseudomonas sp.]]
		+	[[Category: Cho, K J.]]
		+	[[Category: Kim, J K.]]
		+	[[Category: Kim, K H.]]
		+	[[Category: Lee, J H.]]
		+	[[Category: Park, S S.]]
		+	[[Category: Shin, H J.]]
		+	[[Category: Autoproteolysis]]
		+	[[Category: Cephalosporin acylase]]
		+	[[Category: Hydrolase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:43:38 2010''

OCA at 16:48, 18 November 2009

OCA — Wed, 18 Nov 2009 16:48:50 GMT

←Older revision		Revision as of 16:48, 18 November 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3jtr is ON HOLD	+	The entry 3jtr is ON HOLD until Paper Publication

	Authors: Cho, K.J., Kim, J.K., Lee, J.-H., Shin, H.J., Park, S.S., Kim, K.H.		Authors: Cho, K.J., Kim, J.K., Lee, J.-H., Shin, H.J., Park, S.S., Kim, K.H.
Line 7:		Line 7:
	Description: Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis		Description: Mutations in Cephalosporin Acylase Affecting Stability and Autoproteolysis

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 23 08:30~~:48 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:48:49 2009''