3ju9 - Revision history

OCA at 08:03, 6 September 2023

OCA — Wed, 06 Sep 2023 08:03:50 GMT

←Older revision		Revision as of 08:03, 6 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1azd\|1azd]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [https://pdbe.org/3ju9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [https://pdbe.org/3ju9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>	+	[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 28:
	[[Category: Canavalia brasiliensis]]		[[Category: Canavalia brasiliensis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Benevides~~, R G~~]]	+	[[Category: Benevides RG]]
-	[[Category: Bezerra~~, E H.S~~]]	+	[[Category: Bezerra EHS]]
-	[[Category: Bezerra~~, G A~~]]	+	[[Category: Bezerra GA]]
-	[[Category: Bezerra~~, M J.B~~]]	+	[[Category: Bezerra MJB]]
-	[[Category: Cavada~~, B S~~]]	+	[[Category: Cavada BS]]
-	[[Category: Delatorre, P]]	+	[[Category: Delatorre P]]
-	[[Category: Marinho~~, E S~~]]	+	[[Category: Marinho ES]]
-	[[Category: Moura~~, T R~~]]	+	[[Category: Moura TR]]
-	[[Category: Nagano~~, C S~~]]	+	[[Category: Nagano CS]]
-	[[Category: Rocha~~, B A.M]]~~	+	[[Category: Rocha BAM]]
-	~~[[Category: Agglutinin]]~~	+
-	~~[[Category: Conbr]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Manganese]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 05:39, 13 July 2022

OCA — Wed, 13 Jul 2022 05:39:50 GMT

←Older revision		Revision as of 05:39, 13 July 2022
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	<StructureSection load='3ju9' size='340' side='right'caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3ju9' size='340' side='right'caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1azd\|1azd]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [~~http~~://pdbe.org/3ju9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [https://pdbe.org/3ju9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>	+	[[https://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:58, 7 October 2020

OCA — Wed, 07 Oct 2020 06:58:44 GMT

←Older revision		Revision as of 06:58, 7 October 2020
Line 1:		Line 1:

	==Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid==		==Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid==
-	<StructureSection load='3ju9' size='340' side='right' caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3ju9' size='340' side='right'caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://pdbe.org/3ju9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://pdbe.org/3ju9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[Concanavalin A\|Concanavalin A]]	+	*[[Concanavalin 3D structures\|Concanavalin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Canavalia brasiliensis]]		[[Category: Canavalia brasiliensis]]
		+	[[Category: Large Structures]]
	[[Category: Benevides, R G]]		[[Category: Benevides, R G]]
	[[Category: Bezerra, E H.S]]		[[Category: Bezerra, E H.S]]

OCA at 11:41, 5 August 2016

OCA — Fri, 05 Aug 2016 11:41:30 GMT

←Older revision		Revision as of 11:41, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid==		==Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid==
	<StructureSection load='3ju9' size='340' side='right' caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3ju9' size='340' side='right' caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://pdbe.org/3ju9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ju9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ju9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:31, 25 December 2014

OCA — Thu, 25 Dec 2014 18:31:37 GMT

←Older revision		Revision as of 18:31, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CONA_CANBR CONA_CANBR]] Glucose/D-mannose specific lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:40, 8 December 2014

OCA — Mon, 08 Dec 2014 09:40:25 GMT

←Older revision		Revision as of 09:40, 8 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3ju9.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid==
		+	<StructureSection load='3ju9' size='340' side='right' caption='[[3ju9]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ju9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JU9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1azd\|1azd]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ju9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ju9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ju9 RCSB], [http://www.ebi.ac.uk/pdbsum/3ju9 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Diocleinae lectins are highly homologous in their primary structure which features metal binding sites and a carbohydrate recognition domain (CRD). Differences in the biological activity of legume lectins have been widely investigated using hemagglutination inhibition assays, isothermal titration microcalorimetry and co-crystallization with mono- and oligosaccharides. Here we report a new lectin crystal structure (ConBr) extracted from seeds of Canavalia brasiliensis, predict dimannoside binding by docking, identify the alpha-aminobutyric acid (Abu) binding pocket and compare the CRD of ConBr to that of homologous lectins. Based on the hypothesis that the carbohydrate affinity of lectins depends on CRD configuration, the relationship between tridimensional structure and endothelial NO synthase activation was used to clarify differences in biological activity. Our study established a correlation between the position of CRD amino acid side chains and the stimulation of NO release from endothelium.

-	~~{{STRUCTURE_3ju9\| PDB=3ju9 \| SCENE= }}~~	+	Structural analysis of ConBr reveals molecular correlation between the carbohydrate recognition domain and endothelial NO synthase activation.,Bezerra EH, Rocha BA, Nagano CS, Bezerra Gde A, Moura TR, Bezerra MJ, Benevides RG, Sampaio AH, Assreuy AM, Delatorre P, Cavada BS Biochem Biophys Res Commun. 2011 May 20;408(4):566-70. Epub 2011 Apr 19. PMID:21530490<ref>PMID:21530490</ref>

-	~~===Crystal structure~~ of ~~a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21530490}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3ju9]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA].~~	+

	==See Also==		==See Also==
	*[[Concanavalin A\|Concanavalin A]]		*[[Concanavalin A\|Concanavalin A]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021530490<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Canavalia brasiliensis]]		[[Category: Canavalia brasiliensis]]
-	[[Category: Benevides, R G.]]	+	[[Category: Benevides, R G]]
-	[[Category: Bezerra, E H.S.]]	+	[[Category: Bezerra, E H.S]]
-	[[Category: Bezerra, G A.]]	+	[[Category: Bezerra, G A]]
-	[[Category: Bezerra, M J.B.]]	+	[[Category: Bezerra, M J.B]]
-	[[Category: Cavada, B S.]]	+	[[Category: Cavada, B S]]
-	[[Category: Delatorre, P.]]	+	[[Category: Delatorre, P]]
-	[[Category: Marinho, E S.]]	+	[[Category: Marinho, E S]]
-	[[Category: Moura, T R.]]	+	[[Category: Moura, T R]]
-	[[Category: Nagano, C S.]]	+	[[Category: Nagano, C S]]
-	[[Category: Rocha, B A.M.]]	+	[[Category: Rocha, B A.M]]
	[[Category: Agglutinin]]		[[Category: Agglutinin]]
-	[[Category: Canavalia brasiliensis]]
	[[Category: Conbr]]		[[Category: Conbr]]
	[[Category: Lectin]]		[[Category: Lectin]]

OCA at 20:01, 20 October 2012

OCA — Sat, 20 Oct 2012 20:01:42 GMT

←Older revision		Revision as of 20:01, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3ju9]] is a 1 chain structure ~~of [[Concanavalin A]]~~ with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA].	+	[[3ju9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA].

	==See Also==		==See Also==

OCA at 09:11, 27 July 2012

OCA — Fri, 27 Jul 2012 09:11:37 GMT

←Older revision		Revision as of 09:11, 27 July 2012
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	[[Image:3ju9.png\|left\|200px]]		[[Image:3ju9.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3ju9\| PDB=3ju9 \| SCENE= }}		{{STRUCTURE_3ju9\| PDB=3ju9 \| SCENE= }}

	===Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid===		===Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid===

-
-	<!--
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	==See Also==		==See Also==
-	*[[Concanavalin A]]	+	*[[Concanavalin A\|Concanavalin A]]

	==Reference==		==Reference==

OCA: Protected "3ju9" [edit=sysop:move=sysop]

OCA — Wed, 29 Jun 2011 05:21:37 GMT

Protected "3ju9" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:21, 29 June 2011

OCA at 05:21, 29 June 2011

OCA — Wed, 29 Jun 2011 05:21:34 GMT

←Older revision		Revision as of 05:21, 29 June 2011
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-	~~{{Seed}}~~	+	[[Image:3ju9.png\|left\|200px]]
-	[[Image:3ju9.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	===Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid===		===Crystal structure of a lectin from Canavalia brasiliensis seed (ConBr) complexed with alpha-aminobutyric acid===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21530490}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21530490 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21530490}}

	==About this Structure==		==About this Structure==
-	~~3JU9~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA].	+	[[3ju9]] is a 1 chain structure of [[Concanavalin A]] with sequence from [http://en.wikipedia.org/wiki/Canavalia_brasiliensis Canavalia brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JU9 OCA].
		+
		+	==See Also==
		+	*[[Concanavalin A]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021530490</ref><references group="xtra"/>
	[[Category: Canavalia brasiliensis]]		[[Category: Canavalia brasiliensis]]
	[[Category: Benevides, R G.]]		[[Category: Benevides, R G.]]
Line 33:		Line 44:
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:47:29 2010''