3jwa - Revision history

OCA at 08:04, 6 September 2023

OCA — Wed, 06 Sep 2023 08:04:30 GMT

←Older revision		Revision as of 08:04, 6 September 2023
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	<StructureSection load='3jwa' size='340' side='right'caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3jwa' size='340' side='right'caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacterium_freundii"_braak_1928 "bacterium~~ freundii~~" braak 1928~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3JWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JWA FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MPJ:(1~~-~~AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>~~, ~~<scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td>~~<td class="sblockDat">[[2rfv\|2rfv]]~~, ~~[[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]~~<~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [https://pdbe.org/3jwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [https://www.ebi.ac.uk/pdbsum/3jwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jwa ProSAT]</span></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">megL~~ (~~[http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928]~~)~~</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [~~http~~://pdbe.org/3jwa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jwa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jwa ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q84AR1_CITFR Q84AR1_CITFR]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacterium~~ freundii ~~braak 1928~~]]	+	[[Category: Citrobacter freundii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Methionine gamma-lyase]]~~	+	[[Category: Demidkina TV]]
-	[[Category: Demidkina~~, T V~~]]	+	[[Category: Morozova EA]]
-	[[Category: Morozova~~, E A~~]]	+	[[Category: Nikulin AD]]
-	[[Category: Nikulin~~, A D~~]]	+	[[Category: Revtovish SV]]
-	[[Category: Revtovish~~, S V]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Plp-dependent enzyme]]~~	+
-	~~[[Category: Pyridoxal-5'-phosphate~~]]	+

OCA at 08:20, 21 October 2020

OCA — Wed, 21 Oct 2020 08:20:13 GMT

←Older revision		Revision as of 08:20, 21 October 2020
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	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate==		==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate==
-	<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='3jwa' size='340' side='right'caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3JWA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://pdbe.org/3jwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jwa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://pdbe.org/3jwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jwa ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Methionine gamma-lyase\|Methionine gamma-lyase]]	+	*[[Methionine gamma-lyase 3D structures\|Methionine gamma-lyase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium freundii braak 1928]]		[[Category: Bacterium freundii braak 1928]]
		+	[[Category: Large Structures]]
	[[Category: Methionine gamma-lyase]]		[[Category: Methionine gamma-lyase]]
	[[Category: Demidkina, T V]]		[[Category: Demidkina, T V]]

OCA at 08:55, 26 December 2018

OCA — Wed, 26 Dec 2018 08:55:09 GMT

←Older revision		Revision as of 08:55, 26 December 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/3jwa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/3jwa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:48, 11 August 2016

OCA — Thu, 11 Aug 2016 16:48:21 GMT

←Older revision		Revision as of 16:48, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate==		==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate==
	<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JWA FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JWA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:2-~~LYSINE(~~3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-~~YLMETHANE)~~'>LLP</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://pdbe.org/3jwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jwa ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jwa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3jwa" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Methionine gamma-lyase\|Methionine gamma-lyase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:50, 25 January 2015

OCA — Sun, 25 Jan 2015 10:50:46 GMT

←Older revision		Revision as of 10:50, 25 January 2015
Line 2:		Line 2:
	<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JWA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JWA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum]</span></td></tr>
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacterium freundii braak 1928]]
	[[Category: Methionine gamma-lyase]]		[[Category: Methionine gamma-lyase]]
-	[[Category: Demidkina, T V.]]	+	[[Category: Demidkina, T V]]
-	[[Category: Morozova, E A.]]	+	[[Category: Morozova, E A]]
-	[[Category: Nikulin, A D.]]	+	[[Category: Nikulin, A D]]
-	[[Category: Revtovish, S V.]]	+	[[Category: Revtovish, S V]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]
	[[Category: Pyridoxal-5'-phosphate]]		[[Category: Pyridoxal-5'-phosphate]]

OCA at 06:41, 5 November 2014

OCA — Wed, 05 Nov 2014 06:41:23 GMT

←Older revision		Revision as of 06:41, 5 November 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3jwa\| PDB=3jwa \| SCENE= }}~~	+	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate==
-	===Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate===	+	<StructureSection load='3jwa' size='340' side='right' caption='[[3jwa]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3jwa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JWA FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPJ:(1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC+ACID'>MPJ</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[1y4i\|1y4i]], [[2o7c\|2o7c]], [[1ukj\|1ukj]], [[1e5e\|1e5e]], [[3jw9\|3jw9]], [[3jwb\|3jwb]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jwa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jwa RCSB], [http://www.ebi.ac.uk/pdbsum/3jwa PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/3jwa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of Citrobacter freundii methionine gamma-lyase complexes with the substrates of gamma- (L-1-amino-3-methylthiopropylphosphinic acid) and beta- (S-ethyl-L-cysteine) elimination reactions and the competitive inhibitor L-norleucine have been determined at 1.45, 1.8, and 1.63 A resolution, respectively. All three amino acids occupy the active site of the enzyme but do not form a covalent bond with pyridoxal 5'-phosphate. Hydrophobic interactions between the active site residues and the side groups of the substrates and the inhibitor are supposed to cause noncovalent binding. Arg374 and Ser339 are involved in the binding of carboxyl groups of the substrates and the inhibitor. The hydroxyl of Tyr113 is a potential acceptor of a proton from the amino groups of the amino acids.

-	~~==About this Structure==~~	+	Three-dimensional structures of noncovalent complexes of Citrobacter freundii methionine gamma-lyase with substrates.,Revtovich SV, Morozova EA, Khurs EN, Zakomirdina LN, Nikulin AD, Demidkina TV, Khomutov RM Biochemistry (Mosc). 2011 May;76(5):564-70. doi: 10.1134/S0006297911050063. PMID:21639836<ref>PMID:21639836</ref>
-	~~[[3jwa]] is a 1 chain structure~~ with ~~sequence from [http~~:~~//en~~.~~wikipedia~~.~~org~~/~~wiki/Citrobacter_freundii Citrobacter freundii]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id~~=~~3JWA OCA].~~	+
-	~~[[Category: Citrobacter freundii]]~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Methionine gamma-lyase]]		[[Category: Methionine gamma-lyase]]
	[[Category: Demidkina, T V.]]		[[Category: Demidkina, T V.]]

OCA: Protected "3jwa" [edit=sysop:move=sysop]

OCA — Wed, 27 Mar 2013 09:12:48 GMT

Protected "3jwa" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:12, 27 March 2013

OCA at 09:12, 27 March 2013

OCA — Wed, 27 Mar 2013 09:12:46 GMT

←Older revision		Revision as of 09:12, 27 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3jwa.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3jwa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3jwa\| PDB=3jwa \| SCENE= }}		{{STRUCTURE_3jwa\| PDB=3jwa \| SCENE= }}
-
	===Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate===		===Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate===
-

	==About this Structure==		==About this Structure==
-	~~3JWA~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA].	+	[[3jwa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA].
	[[Category: Citrobacter freundii]]		[[Category: Citrobacter freundii]]
	[[Category: Methionine gamma-lyase]]		[[Category: Methionine gamma-lyase]]
Line 24:		Line 13:
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]
	[[Category: Pyridoxal-5'-phosphate]]		[[Category: Pyridoxal-5'-phosphate]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:57:25 2010''

OCA at 09:48, 10 September 2010

OCA — Fri, 10 Sep 2010 09:48:57 GMT

←Older revision		Revision as of 09:48, 10 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3jwa.jpg\|left\|200px]]

-	The ~~entry 3jwa~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3jwa", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3jwa\| PDB=3jwa \| SCENE= }}

-	~~Authors: Revtovish, S.V., Nikulin, A.D., Morozova, E.A., Demidkina, T.V.~~	+	===Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate===

-	Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 14~~ 10:06:~~24 2009~~''	+	==About this Structure==
		+	3JWA is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWA OCA].
		+	[[Category: Citrobacter freundii]]
		+	[[Category: Methionine gamma-lyase]]
		+	[[Category: Demidkina, T V.]]
		+	[[Category: Morozova, E A.]]
		+	[[Category: Nikulin, A D.]]
		+	[[Category: Revtovish, S V.]]
		+	[[Category: Lyase]]
		+	[[Category: Plp-dependent enzyme]]
		+	[[Category: Pyridoxal-5'-phosphate]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:57:25 2010''

OCA at 08:06, 14 October 2009

OCA — Wed, 14 Oct 2009 08:06:25 GMT

←Older revision		Revision as of 08:06, 14 October 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3jwa is ON HOLD	+	The entry 3jwa is ON HOLD until Paper Publication

	Authors: Revtovish, S.V., Nikulin, A.D., Morozova, E.A., Demidkina, T.V.		Authors: Revtovish, S.V., Nikulin, A.D., Morozova, E.A., Demidkina, T.V.
Line 7:		Line 7:
	Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate		Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii with methionine phosphinate

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 30 09~~:00:24 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:06:24 2009''