3k1j - Revision history

OCA at 06:59, 7 October 2020

OCA — Wed, 07 Oct 2020 06:59:44 GMT

←Older revision		Revision as of 06:59, 7 October 2020
Line 1:		Line 1:

	==Crystal structure of Lon protease from Thermococcus onnurineus NA1==		==Crystal structure of Lon protease from Thermococcus onnurineus NA1==
-	<StructureSection load='3k1j' size='340' side='right' caption='[[3k1j]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3k1j' size='340' side='right'caption='[[3k1j]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3K1J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3K1J FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3k1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k1j OCA], [http://pdbe.org/3k1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k1j RCSB], [http://www.ebi.ac.uk/pdbsum/3k1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k1j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3k1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k1j OCA], [http://pdbe.org/3k1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k1j RCSB], [http://www.ebi.ac.uk/pdbsum/3k1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k1j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Theon]]		[[Category: Theon]]
	[[Category: An, Y J]]		[[Category: An, Y J]]

OCA at 09:07, 26 December 2018

OCA — Wed, 26 Dec 2018 09:07:57 GMT

←Older revision		Revision as of 09:07, 26 December 2018
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/3k1j_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/3k1j_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:55, 4 August 2016

OCA — Thu, 04 Aug 2016 15:55:06 GMT

←Older revision		Revision as of 15:55, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Lon protease from Thermococcus onnurineus NA1==		==Crystal structure of Lon protease from Thermococcus onnurineus NA1==
	<StructureSection load='3k1j' size='340' side='right' caption='[[3k1j]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3k1j' size='340' side='right' caption='[[3k1j]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K1J FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K1J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k1j RCSB], [http://www.ebi.ac.uk/pdbsum/3k1j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k1j OCA], [http://pdbe.org/3k1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k1j RCSB], [http://www.ebi.ac.uk/pdbsum/3k1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k1j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k1j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3k1j" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:47, 3 January 2015

OCA — Sat, 03 Jan 2015 22:47:30 GMT

←Older revision		Revision as of 22:47, 3 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}~~	+	==Crystal structure of Lon protease from Thermococcus onnurineus NA1==
-	===Crystal structure of Lon protease from Thermococcus onnurineus NA1===	+	<StructureSection load='3k1j' size='340' side='right' caption='[[3k1j]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	{{~~ABSTRACT_PUBMED_20834233~~}}	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K1J FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k1j RCSB], [http://www.ebi.ac.uk/pdbsum/3k1j PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/3k1j_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lon proteases are distributed in all kingdoms of life and are required for survival of cells under stress. Lon is a tandem fusion of an AAA+ molecular chaperone and a protease with a serine-lysine catalytic dyad. We report the 2.0-A resolution crystal structure of Thermococcus onnurineus NA1 Lon (TonLon). The structure is a three-tiered hexagonal cylinder with a large sequestered chamber accessible through an axial channel. Conserved loops extending from the AAA+ domain combine with an insertion domain containing the membrane anchor to form an apical domain that serves as a gate governing substrate access to an internal unfolding and degradation chamber. Alternating AAA+ domains are in tight- and weak-binding nucleotide states with different domain orientations and intersubunit contacts, reflecting intramolecular dynamics during ATP-driven protein unfolding and translocation. The bowl-shaped proteolytic chamber is contiguous with the chaperone chamber allowing internalized proteins direct access to the proteolytic sites without further gating restrictions.

-	~~==About this Structure==~~	+	Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber.,Cha SS, An YJ, Lee CR, Lee HS, Kim YG, Kim SJ, Kwon KK, De Donatis GM, Lee JH, Maurizi MR, Kang SG EMBO J. 2010 Oct 20;29(20):3520-30. Epub 2010 Sep 10. PMID:20834233<ref>PMID:20834233</ref>
-	~~[[3k1j]] is a 2 chain~~ structure ~~with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Theon Theon]. Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=3K1J OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020834233</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Theon]]		[[Category: Theon]]
-	[[Category: An, Y J.]]	+	[[Category: An, Y J]]
-	[[Category: Cha, S S.]]	+	[[Category: Cha, S S]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Atp-dependent protease]]		[[Category: Atp-dependent protease]]

OCA at 04:13, 13 February 2014

OCA — Thu, 13 Feb 2014 04:13:48 GMT

←Older revision		Revision as of 04:13, 13 February 2014
Line 1:		Line 1:
	{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}		{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}
	===Crystal structure of Lon protease from Thermococcus onnurineus NA1===		===Crystal structure of Lon protease from Thermococcus onnurineus NA1===
-	{{~~ABSTRACT_PUBMED_020834233~~}}	+	{{ABSTRACT_PUBMED_20834233}}

	==About this Structure==		==About this Structure==
-	[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermococcus_onnurineus Thermococcus onnurineus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA].	+	[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA].
-	[[Category: ~~Thermococcus onnurineus~~]]	+
		+	==Reference==
		+	<ref group="xtra">PMID:020834233</ref><references group="xtra"/><references/>
		+	[[Category: Theon]]
	[[Category: An, Y J.]]		[[Category: An, Y J.]]
	[[Category: Cha, S S.]]		[[Category: Cha, S S.]]

OCA: Protected "3k1j" [edit=sysop:move=sysop]

OCA — Wed, 27 Mar 2013 09:30:13 GMT

Protected "3k1j" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:30, 27 March 2013

OCA at 09:30, 27 March 2013

OCA — Wed, 27 Mar 2013 09:30:11 GMT

←Older revision		Revision as of 09:30, 27 March 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3k1j.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3k1j", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}		{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}
-
	===Crystal structure of Lon protease from Thermococcus onnurineus NA1===		===Crystal structure of Lon protease from Thermococcus onnurineus NA1===
-		+	{{ABSTRACT_PUBMED_020834233}}

	==About this Structure==		==About this Structure==
-	~~3K1J~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Thermococcus_onnurineus Thermococcus onnurineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA].	+	[[3k1j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_onnurineus Thermococcus onnurineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA].
	[[Category: Thermococcus onnurineus]]		[[Category: Thermococcus onnurineus]]
	[[Category: An, Y J.]]		[[Category: An, Y J.]]
Line 23:		Line 13:
	[[Category: Nucleotide-binding]]		[[Category: Nucleotide-binding]]
	[[Category: Protease]]		[[Category: Protease]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:44:15 2010''

OCA at 11:35, 22 September 2010

OCA — Wed, 22 Sep 2010 11:35:17 GMT

←Older revision		Revision as of 11:35, 22 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3k1j.jpg\|left\|200px]]

-	The ~~entry 3k1j~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3k1j", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3k1j\| PDB=3k1j \| SCENE= }}

-	~~Authors: Cha, S.S., An, Y.J.~~	+	===Crystal structure of Lon protease from Thermococcus onnurineus NA1===

-	Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 21 10~~:00:~~14 2009~~''	+	==About this Structure==
		+	3K1J is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Thermococcus_onnurineus Thermococcus onnurineus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1J OCA].
		+	[[Category: Thermococcus onnurineus]]
		+	[[Category: An, Y J.]]
		+	[[Category: Cha, S S.]]
		+	[[Category: Atp-binding]]
		+	[[Category: Atp-dependent protease]]
		+	[[Category: Hydrolase]]
		+	[[Category: Nucleotide-binding]]
		+	[[Category: Protease]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:44:15 2010''

OCA at 08:00, 21 October 2009

OCA — Wed, 21 Oct 2009 08:00:14 GMT

←Older revision		Revision as of 08:00, 21 October 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3k1j is ON HOLD	+	The entry 3k1j is ON HOLD until Paper Publication

	Authors: Cha, S.S., An, Y.J.		Authors: Cha, S.S., An, Y.J.
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	Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1		Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~7 13~~:45:01 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:00:14 2009''

OCA: New page: '''Unreleased structure''' The entry 3k1j is ON HOLD Authors: Cha, S.S., An, Y.J. Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1 ''Page seeded by [htt...

OCA — Wed, 07 Oct 2009 11:45:02 GMT

New page: '''Unreleased structure''' The entry 3k1j is ON HOLD Authors: Cha, S.S., An, Y.J. Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1 ''Page seeded by [htt...

New page

'''Unreleased structure'''

The entry 3k1j is ON HOLD

Authors: Cha, S.S., An, Y.J.

Description: Crystal structure of Lon protease from Thermococcus onnurineus NA1

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:45:01 2009''