3keg - Revision history

OCA at 16:11, 1 November 2023

OCA — Wed, 01 Nov 2023 16:11:43 GMT

←Older revision		Revision as of 16:11, 1 November 2023
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	<StructureSection load='3keg' size='340' side='right'caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3keg' size='340' side='right'caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [https://pdbe.org/3keg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [https://www.ebi.ac.uk/pdbsum/3keg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [https://pdbe.org/3keg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [https://www.ebi.ac.uk/pdbsum/3keg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).	+	[https://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Abuhammad, A]]	+	[[Category: Abuhammad A]]
-	[[Category: Laurieri, N]]	+	[[Category: Laurieri N]]
-	[[Category: Lowe, E]]	+	[[Category: Lowe E]]
-	[[Category: Ryan, A]]	+	[[Category: Ryan A]]
-	[[Category: Sim, E]]	+	[[Category: Sim E]]
-	[[Category: Wang, C J]]	+	[[Category: Wang C-J]]
-	[[Category: Westwood, I]]	+	[[Category: Westwood I]]
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Fmn]]~~	+
-	~~[[Category: Methyl red]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Y131f azoreductase~~]]	+

OCA at 07:50, 10 November 2021

OCA — Wed, 10 Nov 2021 07:50:35 GMT

←Older revision		Revision as of 07:50, 10 November 2021
Line 1:		Line 1:

	==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED==		==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED==
-	<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3keg' size='340' side='right'caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KEG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [~~http~~://pdbe.org/3keg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3keg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [https://pdbe.org/3keg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [https://www.ebi.ac.uk/pdbsum/3keg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).	+	[[https://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pseae]]		[[Category: Pseae]]
	[[Category: Abuhammad, A]]		[[Category: Abuhammad, A]]

OCA at 09:22, 26 December 2018

OCA — Wed, 26 Dec 2018 09:22:24 GMT

←Older revision		Revision as of 09:22, 26 December 2018
Line 1:		Line 1:
		+
	==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED==		==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED==
	<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://pdbe.org/3keg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://pdbe.org/3keg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3keg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/3keg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/3keg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 23:05, 7 February 2016

OCA — Sun, 07 Feb 2016 23:05:47 GMT

←Older revision		Revision as of 23:05, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KEG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KEG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~287 Pseudomonas aeruginosa~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://pdbe.org/3keg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3keg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3keg" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas aeruginosa~~]]	+	[[Category: Pseae]]
	[[Category: Abuhammad, A]]		[[Category: Abuhammad, A]]
	[[Category: Laurieri, N]]		[[Category: Laurieri, N]]

OCA at 18:49, 24 December 2014

OCA — Wed, 24 Dec 2014 18:49:23 GMT

←Older revision		Revision as of 18:49, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:00, 18 December 2014

OCA — Thu, 18 Dec 2014 17:00:02 GMT

←Older revision		Revision as of 17:00, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3keg\| PDB=3keg \| SCENE= }}~~	+	==X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED==
-	===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===	+	<StructureSection load='3keg' size='340' side='right' caption='[[3keg]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20057057}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3keg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KEG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MRE:2-(4-DIMETHYLAMINOPHENYL)DIAZENYLBENZOIC+ACID'>MRE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PA0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3keg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3keg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3keg RCSB], [http://www.ebi.ac.uk/pdbsum/3keg PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/3keg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Azoreductase 1 from Pseudomonas aeruginosa strain PAO1 (paAzoR1) catalyses the activation of the prodrug balsalazide and reduces the azo dye methyl red using reduced nicotinamide adenine dinucleotide cofactor as an electron donor. To investigate the mechanism of the enzyme, a Y131F mutation was introduced and the enzymic properties of the mutant were compared with those of the wild-type enzyme. The crystallographic structure of the mutant with methyl red bound was solved at 2.1 A resolution and compared with the wild-type structure. Tyr131 is important in the architecture of the active site but is not essential for enzymic activity.

-	~~==Function==~~	+	Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.,Wang CJ, Laurieri N, Abuhammad A, Lowe E, Westwood I, Ryan A, Sim E Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):2-7., Epub 2009 Dec 25. PMID:20057057<ref>PMID:20057057</ref>
-	~~[[http://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage~~ of ~~azo bond~~ in ~~aromatic azo compounds to~~ the ~~corresponding amines. Requires NADH, but not NADPH~~, as an ~~electron donor~~ for ~~its activity~~ (~~By similarity~~).	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3keg]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:020057057</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Abuhammad, A.]]	+	[[Category: Abuhammad, A]]
-	[[Category: Laurieri, N.]]	+	[[Category: Laurieri, N]]
-	[[Category: Lowe, E.]]	+	[[Category: Lowe, E]]
-	[[Category: Ryan, A.]]	+	[[Category: Ryan, A]]
-	[[Category: Sim, E.]]	+	[[Category: Sim, E]]
-	[[Category: Wang, C J.]]	+	[[Category: Wang, C J]]
-	[[Category: Westwood, I.]]	+	[[Category: Westwood, I]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]
	[[Category: Fmn]]		[[Category: Fmn]]

OCA: Protected "3keg" [edit=sysop:move=sysop]

OCA — Thu, 04 Apr 2013 02:04:16 GMT

Protected "3keg" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:04, 4 April 2013

OCA at 02:04, 4 April 2013

OCA — Thu, 04 Apr 2013 02:04:14 GMT

←Older revision		Revision as of 02:04, 4 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3keg.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3keg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3keg\| PDB=3keg \| SCENE= }}		{{STRUCTURE_3keg\| PDB=3keg \| SCENE= }}
-
	===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===		===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===
		+	{{ABSTRACT_PUBMED_20057057}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20057057}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 20057057 is~~ the ~~PubMed ID number~~.	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_20057057}}~~	+

	==About this Structure==		==About this Structure==
-	~~3KEG~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].	+	[[3keg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20057057~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020057057</ref><references group="xtra"/><references/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Abuhammad, A.]]		[[Category: Abuhammad, A.]]
Line 38:		Line 25:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Y131f azoreductase]]		[[Category: Y131f azoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 08:44:47 2010''

OCA at 06:44, 20 January 2010

OCA — Wed, 20 Jan 2010 06:44:48 GMT

←Older revision		Revision as of 06:44, 20 January 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3keg.~~jpg~~\|left\|200px]]	+	[[Image:3keg.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===		===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20057057}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20057057 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20057057}}

	==About this Structure==		==About this Structure==
-	3KEG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].	+	3KEG is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20057057</ref><references group="xtra"/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Abuhammad, A.]]		[[Category: Abuhammad, A.]]
Line 30:		Line 39:
	[[Category: Y131f azoreductase]]		[[Category: Y131f azoreductase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan ~~13 14~~:39:12 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 08:44:47 2010''

OCA at 12:39, 13 January 2010

OCA — Wed, 13 Jan 2010 12:39:14 GMT

←Older revision		Revision as of 12:39, 13 January 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3keg.jpg\|left\|200px]]

-	The ~~entry 3keg~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3keg", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3keg\| PDB=3keg \| SCENE= }}

-	~~Authors: Wang, C.~~-~~J., Laurieri, N., Abuhammad, A., Lowe, E., Westwood, I., Ryan, A., Sim, E.~~	+	===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===

-	Description: X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 18 18~~:54:~~08 2009~~''	+	==About this Structure==
		+	3KEG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].
		+	[[Category: Pseudomonas aeruginosa]]
		+	[[Category: Abuhammad, A.]]
		+	[[Category: Laurieri, N.]]
		+	[[Category: Lowe, E.]]
		+	[[Category: Ryan, A.]]
		+	[[Category: Sim, E.]]
		+	[[Category: Wang, C J.]]
		+	[[Category: Westwood, I.]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Fmn]]
		+	[[Category: Methyl red]]
		+	[[Category: Nad]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Y131f azoreductase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:39:12 2010''