3koy - Revision history

OCA at 10:17, 21 February 2024

OCA — Wed, 21 Feb 2024 10:17:48 GMT

←Older revision		Revision as of 10:17, 21 February 2024
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	<StructureSection load='3koy' size='340' side='right'caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3koy' size='340' side='right'caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Acest Acest~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetoanaerobium_sticklandii Acetoanaerobium sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ACEST]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ACEST])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [https://pdbe.org/3koy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [https://www.ebi.ac.uk/pdbsum/3koy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3koy ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [~~http~~://pdbe.org/3koy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3koy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3koy ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~OAME_CLOSD OAME_CLOSD]~~] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:11577113</ref> [[http://www.uniprot.org/uniprot/OAMS_CLOSD OAMS_CLOSD]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4-diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:4711468</ref>	+	[https://www.uniprot.org/uniprot/OAME_ACESD OAME_ACESD] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:4711468</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3koy ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3koy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	D-ornithine 4,5-aminomutase (OAM) from Clostridium sticklandii converts D-ornithine to 2,4-diaminopentanoic acid by way of radical propagation from an adenosylcobalamin (AdoCbl) to a pyridoxal 5'-phosphate (PLP) cofactor. We have solved OAM crystal structures in different catalytic states that together demonstrate unusual stability of the AdoCbl Co-C bond and that radical catalysis is coupled to large-scale domain motion. The 2.0-A substrate-free enzyme crystal structure reveals the Rossmann domain, harboring the intact AdoCbl cofactor, is tilted toward the edge of the PLP binding triose-phosphate isomerase barrel domain. The PLP forms an internal aldimine link to the Rossmann domain through Lys(629), effectively locking the enzyme in this "open" pre-catalytic conformation. The distance between PLP and 5'-deoxyadenosyl group is 23 A, and large-scale domain movement is thus required prior to radical catalysis. The OAM crystals contain two Rossmann domains within the asymmetric unit that are unconstrained by the crystal lattice. Surprisingly, the binding of various ligands to OAM crystals (in an oxygen-free environment) leads to transimination in the absence of significant reorientation of the Rossmann domains. In contrast, when performed under aerobic conditions, this leads to extreme disorder in the latter domains correlated with the loss of the 5'-deoxyadenosyl group. Our data indicate turnover and hence formation of the "closed" conformation is occurring within OAM crystals, but that the equilibrium is poised toward the open conformation. We propose that substrate binding induces large-scale domain motion concomitant with a reconfiguration of the 5'-deoxyadenosyl group, triggering radical catalysis in OAM.
-
-	Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.,Wolthers KR, Levy C, Scrutton NS, Leys D J Biol Chem. 2010 Apr 30;285(18):13942-50. Epub 2010 Jan 27. PMID:20106986<ref>PMID:20106986</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3koy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acest~~]]	+	[[Category: Acetoanaerobium sticklandii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Levy~~, C W~~]]	+	[[Category: Levy CW]]
-	[[Category: Leys, D]]	+	[[Category: Leys D]]
-	[[Category: Scrutton~~, N S~~]]	+	[[Category: Scrutton NS]]
-	[[Category: Wolthers~~, K R]]~~	+	[[Category: Wolthers KR]]
-	~~[[Category: Aerobic]]~~	+
-	~~[[Category: D-ornithine 4]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Ornithine complex~~]]	+

OCA at 11:09, 17 July 2019

OCA — Wed, 17 Jul 2019 11:09:29 GMT

←Older revision		Revision as of 11:09, 17 July 2019
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	==Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)==		==Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)==
-	<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3koy' size='340' side='right'caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Acest Acest]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Acest Acest]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
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	==See Also==		==See Also==
-	*[[Aminomutase\|Aminomutase]]	+	*[[Aminomutase 3D structures\|Aminomutase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Acest]]		[[Category: Acest]]
		+	[[Category: Large Structures]]
	[[Category: Levy, C W]]		[[Category: Levy, C W]]
	[[Category: Leys, D]]		[[Category: Leys, D]]

OCA at 09:18, 26 December 2018

OCA — Wed, 26 Dec 2018 09:18:33 GMT

←Older revision		Revision as of 09:18, 26 December 2018
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	<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_12662 Atcc 12662~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Acest Acest]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ~~ATCC 12662~~]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ~~ATCC 12662~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ACEST]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ACEST])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://pdbe.org/3koy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3koy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://pdbe.org/3koy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3koy ProSAT]</span></td></tr>
	</table>		</table>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/3koy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/3koy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 12662~~]]	+	[[Category: Acest]]
	[[Category: Levy, C W]]		[[Category: Levy, C W]]
	[[Category: Leys, D]]		[[Category: Leys, D]]

OCA at 22:47, 5 August 2016

OCA — Fri, 05 Aug 2016 22:47:38 GMT

←Older revision		Revision as of 22:47, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)==		==Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)==
	<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~[clostridium]_sticklandii [clostridium] sticklandii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12662 Atcc 12662]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ~~[Clostridium] sticklandii~~]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ~~[Clostridium] sticklandii~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ATCC 12662]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 ATCC 12662])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://pdbe.org/3koy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3koy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~Q8VPJ5_CLOST Q8VPJ5_CLOST~~]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:~~20106986~~</ref> [[http://www.uniprot.org/uniprot/~~Q8VPJ6_CLOST Q8VPJ6_CLOST~~]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4-diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:~~20106986~~</ref>	+	[[http://www.uniprot.org/uniprot/OAME_CLOSD OAME_CLOSD]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:11577113</ref> [[http://www.uniprot.org/uniprot/OAMS_CLOSD OAMS_CLOSD]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4-diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:4711468</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3koy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3koy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Aminomutase\|Aminomutase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 12662]]
	[[Category: Levy, C W]]		[[Category: Levy, C W]]
	[[Category: Leys, D]]		[[Category: Leys, D]]

OCA at 22:35, 25 December 2014

OCA — Thu, 25 Dec 2014 22:35:57 GMT

←Older revision		Revision as of 22:35, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/[clostridium]_sticklandii [clostridium] sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/[clostridium]_sticklandii [clostridium] sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q8VPJ5_CLOST Q8VPJ5_CLOST]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:20106986</ref> [[http://www.uniprot.org/uniprot/Q8VPJ6_CLOST Q8VPJ6_CLOST]] Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4-diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.<ref>PMID:11577113</ref> <ref>PMID:4711468</ref> <ref>PMID:20106986</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Levy, C W.]]	+	[[Category: Levy, C W]]
-	[[Category: Leys, D.]]	+	[[Category: Leys, D]]
-	[[Category: Scrutton, N S.]]	+	[[Category: Scrutton, N S]]
-	[[Category: Wolthers, K R.]]	+	[[Category: Wolthers, K R]]
	[[Category: Aerobic]]		[[Category: Aerobic]]
	[[Category: D-ornithine 4]]		[[Category: D-ornithine 4]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
	[[Category: Ornithine complex]]		[[Category: Ornithine complex]]

OCA at 13:08, 29 September 2014

OCA — Mon, 29 Sep 2014 13:08:24 GMT

←Older revision		Revision as of 13:08, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3koy.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)==
		+	<StructureSection load='3koy' size='340' side='right' caption='[[3koy]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/[clostridium]_sticklandii [clostridium] sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KOY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=Z97:(E)-N~5~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)-L-ORNITHINE'>Z97</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kow\|3kow]], [[3kox\|3kox]], [[3koz\|3koz]], [[3kp0\|3kp0]], [[3kp1\|3kp1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">oraE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii]), oraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1511 [Clostridium] sticklandii])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3koy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3koy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3koy RCSB], [http://www.ebi.ac.uk/pdbsum/3koy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/3koy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	D-ornithine 4,5-aminomutase (OAM) from Clostridium sticklandii converts D-ornithine to 2,4-diaminopentanoic acid by way of radical propagation from an adenosylcobalamin (AdoCbl) to a pyridoxal 5'-phosphate (PLP) cofactor. We have solved OAM crystal structures in different catalytic states that together demonstrate unusual stability of the AdoCbl Co-C bond and that radical catalysis is coupled to large-scale domain motion. The 2.0-A substrate-free enzyme crystal structure reveals the Rossmann domain, harboring the intact AdoCbl cofactor, is tilted toward the edge of the PLP binding triose-phosphate isomerase barrel domain. The PLP forms an internal aldimine link to the Rossmann domain through Lys(629), effectively locking the enzyme in this "open" pre-catalytic conformation. The distance between PLP and 5'-deoxyadenosyl group is 23 A, and large-scale domain movement is thus required prior to radical catalysis. The OAM crystals contain two Rossmann domains within the asymmetric unit that are unconstrained by the crystal lattice. Surprisingly, the binding of various ligands to OAM crystals (in an oxygen-free environment) leads to transimination in the absence of significant reorientation of the Rossmann domains. In contrast, when performed under aerobic conditions, this leads to extreme disorder in the latter domains correlated with the loss of the 5'-deoxyadenosyl group. Our data indicate turnover and hence formation of the "closed" conformation is occurring within OAM crystals, but that the equilibrium is poised toward the open conformation. We propose that substrate binding induces large-scale domain motion concomitant with a reconfiguration of the 5'-deoxyadenosyl group, triggering radical catalysis in OAM.

-	~~{{STRUCTURE_3koy\| PDB=3koy \| SCENE= }}~~	+	Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.,Wolthers KR, Levy C, Scrutton NS, Leys D J Biol Chem. 2010 Apr 30;285(18):13942-50. Epub 2010 Jan 27. PMID:20106986<ref>PMID:20106986</ref>

-	~~===Crystal Structure of ornithine 4~~,~~5 aminomutase in complex with ornithine (Aerobic)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20106986}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3koy]] is~~ a ~~8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/[clostridium]_sticklandii [clostridium] sticklandii]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020106986<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Levy, C W.]]		[[Category: Levy, C W.]]
	[[Category: Leys, D.]]		[[Category: Leys, D.]]

OCA: Protected "3koy" [edit=sysop:move=sysop]

OCA — Wed, 24 Oct 2012 06:42:09 GMT

Protected "3koy" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:42, 24 October 2012

OCA at 06:42, 24 October 2012

OCA — Wed, 24 Oct 2012 06:42:08 GMT

←Older revision		Revision as of 06:42, 24 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3koy.png\|left\|200px]]		[[Image:3koy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3koy", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3koy\| PDB=3koy \| SCENE= }}		{{STRUCTURE_3koy\| PDB=3koy \| SCENE= }}

	===Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)===		===Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20106986}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20106986 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20106986}}		{{ABSTRACT_PUBMED_20106986}}

	==About this Structure==		==About this Structure==
-	~~3KOY~~ is a 8 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/~~Clostridium_sticklandii Clostridium~~ sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].	+	[[3koy]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/[clostridium]_sticklandii [clostridium] sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20106986~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020106986</ref><references group="xtra"/>
-	~~[[Category: Clostridium sticklandii]]~~	+
	[[Category: Levy, C W.]]		[[Category: Levy, C W.]]
	[[Category: Leys, D.]]		[[Category: Leys, D.]]
Line 33:		Line 20:
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
	[[Category: Ornithine complex]]		[[Category: Ornithine complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:33:40 2010''

OCA at 07:33, 12 May 2010

OCA — Wed, 12 May 2010 07:33:40 GMT

←Older revision		Revision as of 07:33, 12 May 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3koy.~~jpg~~\|left\|200px]]	+	[[Image:3koy.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)===		===Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20106986}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20106986 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20106986}}

	==About this Structure==		==About this Structure==
	3KOY is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Clostridium_sticklandii Clostridium sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].		3KOY is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Clostridium_sticklandii Clostridium sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20106986</ref><references group="xtra"/>
	[[Category: Clostridium sticklandii]]		[[Category: Clostridium sticklandii]]
	[[Category: Levy, C W.]]		[[Category: Levy, C W.]]
Line 22:		Line 31:
	[[Category: Aerobic]]		[[Category: Aerobic]]
	[[Category: D-ornithine 4]]		[[Category: D-ornithine 4]]
		+	[[Category: Metal binding protein]]
	[[Category: Ornithine complex]]		[[Category: Ornithine complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 27 20~~:03:46 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:33:40 2010''

OCA at 18:03, 27 January 2010

OCA — Wed, 27 Jan 2010 18:03:46 GMT

←Older revision		Revision as of 18:03, 27 January 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3koy.jpg\|left\|200px]]

-	The ~~entry 3koy~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3koy", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3koy\| PDB=3koy \| SCENE= }}

-	~~Authors: Wolthers~~, ~~K.R., Levy, C.W., Scrutton, N.S., Leys, D.~~	+	===Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)===

-	Description: Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 16 12~~:35:~~16 2009~~''	+	==About this Structure==
		+	3KOY is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Clostridium_sticklandii Clostridium sticklandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOY OCA].
		+	[[Category: Clostridium sticklandii]]
		+	[[Category: Levy, C W.]]
		+	[[Category: Leys, D.]]
		+	[[Category: Scrutton, N S.]]
		+	[[Category: Wolthers, K R.]]
		+	[[Category: Aerobic]]
		+	[[Category: D-ornithine 4]]
		+	[[Category: Ornithine complex]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 20:03:46 2010''