3kyi - Revision history

OCA at 16:18, 1 November 2023

OCA — Wed, 01 Nov 2023 16:18:23 GMT

←Older revision		Revision as of 16:18, 1 November 2023
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	<StructureSection load='3kyi' size='340' side='right'caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kyi' size='340' side='right'caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"luteovulum_sphaeroides"_(van_niel_1944)_suresh_et_al._2019 "luteovulum~~ sphaeroides~~" (van niel 1944) suresh et al. 2019~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KYI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides Cereibacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KYI FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3kyj\|3kyj]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>cheA3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1063~~ "~~Luteovulum sphaeroides~~" ~~(van Niel 1944) Suresh et al. 2019]), cheY6 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Luteovulum sphaeroides" (van Niel 1944) Suresh et al. 2019])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [https://pdbe.org/3kyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [https://www.ebi.ac.uk/pdbsum/3kyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [https://pdbe.org/3kyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [https://www.ebi.ac.uk/pdbsum/3kyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8KLS0_CERSP Q8KLS0_CERSP]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cereibacter sphaeroides]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Armitage~~, J P~~]]	+	[[Category: Armitage JP]]
-	[[Category: Bell~~, C H~~]]	+	[[Category: Bell CH]]
-	[[Category: Porter~~, S L~~]]	+	[[Category: Porter SL]]
-	[[Category: Stuart~~, D I]]~~	+	[[Category: Stuart DI]]
-	~~[[Category: Histidine kinase]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Phosphorylation]]~~	+
-	~~[[Category: Protein-protein interaction]]~~	+
-	~~[[Category: Response regulator]]~~	+
-	~~[[Category: Specificity]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:52, 10 November 2021

OCA — Wed, 10 Nov 2021 07:52:05 GMT

←Older revision		Revision as of 07:52, 10 November 2021
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	==Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides==		==Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides==
-	<StructureSection load='3kyi' size='340' side='right' caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3kyi' size='340' side='right'caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"~~rhodococcus_capsulatus~~"~~_molisch_1907~~ "~~rhodococcus capsulatus~~" ~~molisch 1907~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KYI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"luteovulum_sphaeroides"_(van_niel_1944)_suresh_et_al._2019 "luteovulum sphaeroides" (van niel 1944) suresh et al. 2019]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KYI FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3kyj\|3kyj]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "~~Rhodococcus capsulatus~~" ~~Molisch 1907~~]), cheY6 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "~~Rhodococcus capsulatus~~" ~~Molisch 1907~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Luteovulum sphaeroides" (van Niel 1944) Suresh et al. 2019]), cheY6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Luteovulum sphaeroides" (van Niel 1944) Suresh et al. 2019])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [~~http~~://pdbe.org/3kyi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3kyi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [https://pdbe.org/3kyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [https://www.ebi.ac.uk/pdbsum/3kyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyi_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyi_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhodococcus capsulatus molisch 1907~~]]	+	[[Category: Large Structures]]
	[[Category: Armitage, J P]]		[[Category: Armitage, J P]]
	[[Category: Bell, C H]]		[[Category: Bell, C H]]

OCA at 08:44, 1 November 2017

OCA — Wed, 01 Nov 2017 08:44:34 GMT

←Older revision		Revision as of 08:44, 1 November 2017
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907]), cheY6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907]), cheY6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [http://pdbe.org/3kyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [http://www.ebi.ac.uk/pdbsum/3kyi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [http://pdbe.org/3kyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [http://www.ebi.ac.uk/pdbsum/3kyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kyi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:07, 20 June 2016

OCA — Mon, 20 Jun 2016 08:07:16 GMT

←Older revision		Revision as of 08:07, 20 June 2016
Line 1:		Line 1:
		+
	==Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides==		==Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides==
	<StructureSection load='3kyi' size='340' side='right' caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3kyi' size='340' side='right' caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodobacter_sphaeroides Rhodobacter sphaeroides~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KYI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"rhodococcus_capsulatus"_molisch_1907 "rhodococcus capsulatus" molisch 1907]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KYI FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 ~~Rhodobacter sphaeroides~~]), cheY6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 ~~Rhodobacter sphaeroides~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907]), cheY6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 "Rhodococcus capsulatus" Molisch 1907])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [http://www.ebi.ac.uk/pdbsum/3kyi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [http://pdbe.org/3kyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [http://www.ebi.ac.uk/pdbsum/3kyi PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kyi ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3kyi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhodobacter sphaeroides~~]]	+	[[Category: Rhodococcus capsulatus molisch 1907]]
	[[Category: Armitage, J P]]		[[Category: Armitage, J P]]
	[[Category: Bell, C H]]		[[Category: Bell, C H]]

OCA at 16:31, 18 December 2014

OCA — Thu, 18 Dec 2014 16:31:00 GMT

←Older revision		Revision as of 16:31, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3kyi\| PDB=3kyi \| SCENE= }}~~	+	==Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides==
-	===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===	+	<StructureSection load='3kyi' size='340' side='right' caption='[[3kyi]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20161720}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3kyi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KYI FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3kyj\|3kyj]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cheA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 Rhodobacter sphaeroides]), cheY6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1063 Rhodobacter sphaeroides])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kyi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3kyi RCSB], [http://www.ebi.ac.uk/pdbsum/3kyi PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3kyi_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two-component signal transduction pathways comprising histidine protein kinases (HPKs) and their response regulators (RRs) are widely used to control bacterial responses to environmental challenges. Some bacteria have over 150 different two-component pathways, and the specificity of the phosphotransfer reactions within these systems is tightly controlled to prevent unwanted crosstalk. One of the best understood two-component signalling pathways is the chemotaxis pathway. Here, we present the 1.40 A crystal structure of the histidine-containing phosphotransfer domain of the chemotaxis HPK, CheA(3), in complex with its cognate RR, CheY(6). A methionine finger on CheY(6) that nestles in a hydrophobic pocket in CheA(3) was shown to be important for the interaction and was found to only occur in the cognate RRs of CheA(3), CheY(6), and CheB(2). Site-directed mutagenesis of this methionine in combination with two adjacent residues abolished binding, as shown by surface plasmon resonance studies, and phosphotransfer from CheA(3)-P to CheY(6). Introduction of this methionine and an adjacent alanine residue into a range of noncognate CheYs, dramatically changed their specificity, allowing protein interaction and rapid phosphotransfer from CheA(3)-P. The structure presented here has allowed us to identify specificity determinants for the CheA-CheY interaction and subsequently to successfully reengineer phosphotransfer signalling. In summary, our results provide valuable insight into how cells mediate specificity in one of the most abundant signalling pathways in biology, two-component signal transduction.

-	~~==About this Structure==~~	+	Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex.,Bell CH, Porter SL, Strawson A, Stuart DI, Armitage JP PLoS Biol. 2010 Feb 9;8(2):e1000306. PMID:20161720<ref>PMID:20161720</ref>
-	~~[[3kyi]] is~~ a 2 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020161720</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Rhodobacter sphaeroides]]		[[Category: Rhodobacter sphaeroides]]
-	[[Category: Armitage, J P.]]	+	[[Category: Armitage, J P]]
-	[[Category: Bell, C H.]]	+	[[Category: Bell, C H]]
-	[[Category: Porter, S L.]]	+	[[Category: Porter, S L]]
-	[[Category: Stuart, D I.]]	+	[[Category: Stuart, D I]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Kinase]]		[[Category: Kinase]]

OCA: Protected "3kyi" [edit=sysop:move=sysop]

OCA — Thu, 04 Apr 2013 20:45:46 GMT

Protected "3kyi" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:45, 4 April 2013

OCA at 20:45, 4 April 2013

OCA — Thu, 04 Apr 2013 20:45:44 GMT

←Older revision		Revision as of 20:45, 4 April 2013
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-	{{Seed}}
-	[[Image:3kyi.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3kyi", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3kyi\| PDB=3kyi \| SCENE= }}		{{STRUCTURE_3kyi\| PDB=3kyi \| SCENE= }}
-
	===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===		===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20161720}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20161720 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20161720}}		{{ABSTRACT_PUBMED_20161720}}

	==About this Structure==		==About this Structure==
-	~~3KYI~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].	+	[[3kyi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20161720~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020161720</ref><references group="xtra"/><references/>
	[[Category: Rhodobacter sphaeroides]]		[[Category: Rhodobacter sphaeroides]]
	[[Category: Armitage, J P.]]		[[Category: Armitage, J P.]]
Line 36:		Line 20:
	[[Category: Specificity]]		[[Category: Specificity]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:27:31 2010''

OCA at 06:27, 24 March 2010

OCA — Wed, 24 Mar 2010 06:27:32 GMT

←Older revision		Revision as of 06:27, 24 March 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3kyi.~~jpg~~\|left\|200px]]	+	[[Image:3kyi.png\|left\|200px]]

	<!--		<!--
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	===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===		===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20161720}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20161720 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20161720}}

	==About this Structure==		==About this Structure==
	3KYI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].		3KYI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20161720</ref><references group="xtra"/>
	[[Category: Rhodobacter sphaeroides]]		[[Category: Rhodobacter sphaeroides]]
	[[Category: Armitage, J P.]]		[[Category: Armitage, J P.]]
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	[[Category: Transferase]]		[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 17 10~~:52:03 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 24 08:27:31 2010''

OCA at 08:52, 17 February 2010

OCA — Wed, 17 Feb 2010 08:52:04 GMT

←Older revision		Revision as of 08:52, 17 February 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3kyi.jpg\|left\|200px]]

-	The ~~entry 3kyi~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3kyi", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3kyi\| PDB=3kyi \| SCENE= }}

-	~~Authors: Bell, C.H., Porter, S.L., Armitage, J.P., Stuart, D.I~~.	+	===Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides===

-	Description: Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 23 09~~:24:~~41 2009~~''	+	==About this Structure==
		+	3KYI is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides Rhodobacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KYI OCA].
		+	[[Category: Rhodobacter sphaeroides]]
		+	[[Category: Armitage, J P.]]
		+	[[Category: Bell, C H.]]
		+	[[Category: Porter, S L.]]
		+	[[Category: Stuart, D I.]]
		+	[[Category: Histidine kinase]]
		+	[[Category: Kinase]]
		+	[[Category: Phosphorylation]]
		+	[[Category: Protein-protein interaction]]
		+	[[Category: Response regulator]]
		+	[[Category: Specificity]]
		+	[[Category: Transferase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:52:03 2010''

OCA at 07:24, 23 December 2009

OCA — Wed, 23 Dec 2009 07:24:42 GMT

←Older revision		Revision as of 07:24, 23 December 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3kyi is ON HOLD	+	The entry 3kyi is ON HOLD until Paper Publication

-	Authors: ~~Christian~~ H. ~~Bell~~, ~~Steven~~ L. ~~Porter~~, ~~Judith~~ P. ~~Armitage~~, ~~David~~ I. ~~Stuart~~	+	Authors: Bell, C.H., Porter, S.L., Armitage, J.P., Stuart, D.I.

	Description: Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides		Description: Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec ~~16 12~~:39:00 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 09:24:41 2009''