3l4p - Revision history

OCA at 16:20, 1 November 2023

OCA — Wed, 01 Nov 2023 16:20:50 GMT

←Older revision		Revision as of 16:20, 1 November 2023
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	<StructureSection load='3l4p' size='340' side='right'caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3l4p' size='340' side='right'caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Desulfovibrio_gigas Desulfovibrio~~ gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3L4P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Megalodesulfovibrio_gigas Megalodesulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L4P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AST:ARSENITE'>AST</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.45Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AST:ARSENITE'>AST</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [https://pdbe.org/3l4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [https://www.ebi.ac.uk/pdbsum/3l4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l4p ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [~~http~~://pdbe.org/3l4p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3l4p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3l4p ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/MOP_MEGGA MOP_MEGGA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Desulfovibrio gigas]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Boer, D R~~]]	+	[[Category: Megalodesulfovibrio gigas]]
-	[[Category: ~~Romao, M J~~]]	+	[[Category: Boer DR]]
-	[[Category: ~~2fe-2]]~~	+	[[Category: Romao MJ]]
-	~~[[Category: Aldehyde oxidoreductase]]~~	+
-	~~[[Category: Arsenite inhibition]]~~	+
-	~~[[Category: Fad]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Iron-sulfur]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Molybdenum]]~~	+
-	~~[[Category: Molybdenum-containing enzyme]]~~	+
-	~~[[Category: Nad]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Reduced form]]~~	+
-	~~[[Category: Xanthine oxidase family~~]]	+

OCA at 11:20, 13 November 2019

OCA — Wed, 13 Nov 2019 11:20:12 GMT

←Older revision		Revision as of 11:20, 13 November 2019
Line 1:		Line 1:

	==Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-==		==Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-==
-	<StructureSection load='3l4p' size='340' side='right' caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>	+	<StructureSection load='3l4p' size='340' side='right'caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4P FirstGlance]. <br>		<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4P FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]	+	*[[Alcohol dehydrogenase 3D structures\|Alcohol dehydrogenase 3D structures]]
-	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]	+	*[[Aldehyde dehydrogenase 3D structures\|Aldehyde dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
		+	[[Category: Large Structures]]
	[[Category: Boer, D R]]		[[Category: Boer, D R]]
	[[Category: Romao, M J]]		[[Category: Romao, M J]]

OCA at 07:16, 2 January 2019

OCA — Wed, 02 Jan 2019 07:16:44 GMT

←Older revision		Revision as of 07:16, 2 January 2019
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l4p_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l4p_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 39:		Line 39:
	[[Category: Boer, D R]]		[[Category: Boer, D R]]
	[[Category: Romao, M J]]		[[Category: Romao, M J]]
		+	[[Category: 2fe-2]]
	[[Category: Aldehyde oxidoreductase]]		[[Category: Aldehyde oxidoreductase]]
	[[Category: Arsenite inhibition]]		[[Category: Arsenite inhibition]]

OCA at 19:25, 11 August 2016

OCA — Thu, 11 Aug 2016 19:25:24 GMT

←Older revision		Revision as of 19:25, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-==		==Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-==
	<StructureSection load='3l4p' size='340' side='right' caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>		<StructureSection load='3l4p' size='340' side='right' caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [http://www.ebi.ac.uk/pdbsum/3l4p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [http://pdbe.org/3l4p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [http://www.ebi.ac.uk/pdbsum/3l4p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l4p ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l4p ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3l4p" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:47, 20 January 2015

OCA — Tue, 20 Jan 2015 09:47:20 GMT

←Older revision		Revision as of 09:47, 20 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4P FirstGlance]. <br>		<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4P FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AST:ARSENITE'>AST</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AST:ARSENITE'>AST</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [http://www.ebi.ac.uk/pdbsum/3l4p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [http://www.ebi.ac.uk/pdbsum/3l4p PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
-	[[Category: Boer, D R.]]	+	[[Category: Boer, D R]]
-	[[Category: Romao, M J.]]	+	[[Category: Romao, M J]]
	[[Category: Aldehyde oxidoreductase]]		[[Category: Aldehyde oxidoreductase]]
	[[Category: Arsenite inhibition]]		[[Category: Arsenite inhibition]]

OCA at 13:34, 29 September 2014

OCA — Mon, 29 Sep 2014 13:34:08 GMT

←Older revision		Revision as of 13:34, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~3l4p.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-==
		+	<StructureSection load='3l4p' size='340' side='right' caption='[[3l4p]], [[Resolution\|resolution]] 1.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L4P FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AST:ARSENITE'>AST</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PCD:(MOLYBDOPTERIN-CYTOSINE+DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V)'>PCD</scene>, <scene name='pdbligand=URE:UREA'>URE</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vlb\|1vlb]], [[1dgj\|1dgj]], [[3fah\|3fah]], [[3fc4\|3fc4]], [[1sij\|1sij]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_dehydrogenase_(FAD-independent) Aldehyde dehydrogenase (FAD-independent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.7 1.2.99.7] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l4p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l4p RCSB], [http://www.ebi.ac.uk/pdbsum/3l4p PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l4p_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two arsenite-inhibited forms of each of the aldehyde oxidoreductases from Desulfovibrio gigas and Desulfovibrio desulfuricans have been studied by X-ray crystallography and electron paramagnetic resonance (EPR) spectroscopy. The molybdenum site of these enzymes shows a distorted square-pyramidal geometry in which two ligands, a hydroxyl/water molecule (the catalytic labile site) and a sulfido ligand, have been shown to be essential for catalysis. Arsenite addition to active as-prepared enzyme or to a reduced desulfo form yields two different species called A and B, respectively, which show different Mo(V) EPR signals. Both EPR signals show strong hyperfine and quadrupolar couplings with an arsenic nucleus, which suggests that arsenic interacts with molybdenum through an equatorial ligand. X-ray data of single crystals prepared from EPR-active samples show in both inhibited forms that the arsenic atom interacts with the molybdenum ion through an oxygen atom at the catalytic labile site and that the sulfido ligand is no longer present. EPR and X-ray data indicate that the main difference between both species is an equatorial ligand to molybdenum which was determined to be an oxo ligand in species A and a hydroxyl/water ligand in species B. The conclusion that the sulfido ligand is not essential to determine the EPR properties in both Mo-As complexes is achieved through EPR measurements on a substantial number of randomly oriented chemically reduced crystals immediately followed by X-ray studies on one of those crystals. EPR saturation studies show that the electron transfer pathway, which is essential for catalysis, is not modified upon inhibition.

-	~~{{STRUCTURE_3l4p\| PDB=3l4p \| SCENE= }}~~	+	Correlating EPR and X-ray structural analysis of arsenite-inhibited forms of aldehyde oxidoreductase.,Thapper A, Boer DR, Brondino CD, Moura JJ, Romao MJ J Biol Inorg Chem. 2007 Mar;12(3):353-66. Epub 2006 Dec 1. PMID:17139522<ref>PMID:17139522</ref>

-	~~===Crystal structure~~ of the ~~Aldehyde Dehydrogenase (a~~.k.a. ~~AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17139522}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3l4p]] is a 1 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].	+

	==See Also==		==See Also==
	*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]		*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]
	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]		*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017139522<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
	[[Category: Boer, D R.]]		[[Category: Boer, D R.]]

OCA at 17:36, 20 October 2012

OCA — Sat, 20 Oct 2012 17:36:33 GMT

←Older revision		Revision as of 17:36, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3l4p]] is a 1 chain structure ~~of [[Alcohol dehydrogenase]] and [[Aldehyde dehydrogenase]]~~ with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].	+	[[3l4p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].

	==See Also==		==See Also==

OCA: Protected "3l4p" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 01:28:14 GMT

Protected "3l4p" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:28, 27 July 2012

OCA at 01:28, 27 July 2012

OCA — Fri, 27 Jul 2012 01:28:12 GMT

←Older revision		Revision as of 01:28, 27 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3l4p.png\|left\|200px]]
-	[[Image:3l4p.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3l4p", creates the "Structure Box" on the page.
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_3l4p\| PDB=3l4p \| SCENE= }}		{{STRUCTURE_3l4p\| PDB=3l4p \| SCENE= }}

	===Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-===		===Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17139522}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17139522 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17139522}}		{{ABSTRACT_PUBMED_17139522}}

	==About this Structure==		==About this Structure==
-	~~3L4P~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].	+	[[3l4p]] is a 1 chain structure of [[Alcohol dehydrogenase]] and [[Aldehyde dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].
		+
		+	==See Also==
		+	*[[Alcohol dehydrogenase\|Alcohol dehydrogenase]]
		+	*[[Aldehyde dehydrogenase\|Aldehyde dehydrogenase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17139522~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017139522</ref><references group="xtra"/>
	[[Category: Desulfovibrio gigas]]		[[Category: Desulfovibrio gigas]]
	[[Category: Boer, D R.]]		[[Category: Boer, D R.]]
	[[Category: Romao, M J.]]		[[Category: Romao, M J.]]
-	[[Category: 2fe-2]]
	[[Category: Aldehyde oxidoreductase]]		[[Category: Aldehyde oxidoreductase]]
	[[Category: Arsenite inhibition]]		[[Category: Arsenite inhibition]]
Line 41:		Line 32:
	[[Category: Reduced form]]		[[Category: Reduced form]]
	[[Category: Xanthine oxidase family]]		[[Category: Xanthine oxidase family]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:20:27 2010''

OCA at 08:20, 17 February 2010

OCA — Wed, 17 Feb 2010 08:20:28 GMT

←Older revision		Revision as of 08:20, 17 February 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3l4p.jpg\|left\|200px]]

-	The ~~entry 3l4p~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3l4p", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3l4p\| PDB=3l4p \| SCENE= }}

-	~~Authors: Boer, D~~.R.~~, Romao, M.J~~.	+	===Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-===

-	Description: Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 30 13~~:48:~~41 2009~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_17139522}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 17139522 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_17139522}}
		+
		+	==About this Structure==
		+	3L4P is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zcs 1zcs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L4P OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:17139522</ref><references group="xtra"/>
		+	[[Category: Desulfovibrio gigas]]
		+	[[Category: Boer, D R.]]
		+	[[Category: Romao, M J.]]
		+	[[Category: 2fe-2]]
		+	[[Category: Aldehyde oxidoreductase]]
		+	[[Category: Arsenite inhibition]]
		+	[[Category: Fad]]
		+	[[Category: Flavoprotein]]
		+	[[Category: Iron]]
		+	[[Category: Iron-sulfur]]
		+	[[Category: Metal-binding]]
		+	[[Category: Molybdenum]]
		+	[[Category: Molybdenum-containing enzyme]]
		+	[[Category: Nad]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Reduced form]]
		+	[[Category: Xanthine oxidase family]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:20:27 2010''